IMAGE: Stem Cells and Development is dedicated to communication and objective analysis of developments in the biology, characteristics, and therapeutic utility of stem cells, especially those of the hematopoietic system.... view New Rochelle, NY, July 3, 2018-The promise of generating truly pluripotent stem cells from terminally differentiated adult cell types continues to captivate scientists who envision great potential for therapeutic interventions. The two primary methods involve either the replacement of oocyte nuclei with adult somatic cell nuclei--a process known as somatic cell nuclear transfer --or the introduction, typically by viruses, of a cocktail of specific transcription factors to create induced pluripotent stem cells .