WHO issues warning over superbugs

Superbugs which cause sepsis, pneumonia, and salmonella will soon be resistant to antibiotics, the World Health Organisation has warned as it called on governments to stop relying on pharmaceutical companies to solve the crisis. Health officials have drawn up a list of 12 types of bacteria which pose the “greatest threat to human health” because soon no drugs will be able to fight them off.

Cempra shares tumble 28% premarket after FDA says it can’t approve pneumonia drug application

The letter says that the FDA cannot approve the NDAs in their current form and says the company must provide additional safety data and resolve unspecified issues with its manufacturing facility. “Based on their review of the NDAs, the CRL stated that the FDA determined the risk of hepatotoxicity had not been adequately characterized,” the company said in a statement.