Although Irvington is still a suburban “bedroom community”, with a large number of people commuting into New York City to work, there are also several notable businesses and institutions located in the village, such as:
- Columbia University‘s Nevis Laboratories is a research center specializing in the preparation, design, and construction of high-energy particle and nuclear experiments and equipment which are transported to accelerators such as Fermilab, CERN and Brookhaven National Laboratory. The resulting data is analyzed at Nevis using their extensive computer systems. Twelve faculty members, fourteen postdoctoral research scientists and twenty graduate students work at the lab, along with an engineering and technical staff of twenty. The grounds also accommodate an agricultural research center. “Nevis” was the estate of Alexander Hamilton’s son, and was named after Hamilton’s birthplace in Jamaica.
- Eileen Fisher, a clothing design company, has corporate offices and a retail shop at Bridge Street Properties by the Hudson. In addition, in 2017, it opened in Irvington its first company-owned factory.
- Flat World Knowledge is an online publisher of college-level open textbooks.
- House Party, Inc., an experimental marketing firm which specializes in arranging parties to promote their clients’ products, has its offices at 50 South Buckhout Street.
- Hudson Loft – In August 2016 it was announced that a 9,000 square feet event space on the top floor of a three=story warehouse at 2 Astor Place in Irvington would be available beginning at the end of September for weddings, parties and other events. The space features panoramic views of the Hudson River and a 6,000 square foot main space.
- Lockard & Wechsler, a direct marketing agency located at Bridge Street Properties.
- Monte Nido Treatment Center, a residential treatment center for eating disorders, was announced in May 2014 to be planned for Irvington. It would be located in a 10,000 square foot, 20-room mansion at 100 South Broadway near Clinton Avenue. The organization has residential facilities in Malibu and Agoura Hills in California and in Boston, as well as a day-clinic in New York City.
- Natural Market Food Group, the parent company of the “Mrs. Green’s Natural Market” supermarket chain, which operates primarily in the Hudson Valley area, has its offices in Irvington.
- PECO Pallet, a pooled pallet provider headquartered in Irvington
- STRATA Skin Sciences, formerly MELA Sciences, is a medical device company that focuses on the design and development of a non-invasive, point-of-care instruments to assist in the early diagnosis of melanoma. In 2015, the company acquired XTRAC and PhotoMedex.
- The Student Center, a community website for teenagers and college students, has offices on Main Street.
- BrightFarms, a company that grows salad greens, is headquartered in Irvington.[