A graduate of Fox Lane High School, Di Guglielmo also attended Union College before joining the family business, the Bedford Nursery in Bedford, working alongside his parents. He is survived by his parents Michael and Rosa Di Guglielmo, his brother Anthony Di Guglielmo; sister Rina Di Guglielmo Krone; nieces Daniella, Alissa, Ariana and Alexa, and extended family and friends.