When author Niki Kapsambelis met Lori DeMoe in 2009, Lori already had some early symptoms of the disease that had already claimed the lives of her grandmother, dad, older brother and several extended relatives. But, Kapsambelis said, unless you knew the odds Lori faced as the member of a family predisposed to early onset Alzheimer’s, you would never believe she was destined to lose her battle with the fatal disease.