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Category: Stem Cell Research
New research identifies signal that appears to trigger retinal regeneration in zebrafish
If you were a fish and your retina was damaged, it could repair itself and your vision would be restored in a few weeks. Sadly, human eyes don’t have this beneficial ability.
Diabetes drug may be effective against deadly form of breast cancer, study suggests
Researchers in China have discovered that a metabolic enzyme called AKR1B1 drives an aggressive type of breast cancer . The study, “AKR1B1 promotes basal-like breast cancer progression by a positive feedback loop that activates the EMT program,” which has been published in The Journal of Experimental Medicine , suggests that an inhibitor of this enzyme currently used to treat diabetes patients could be an effective therapy for this frequently deadly form of cancer .
Stem cell treatment changed the life of one guest at Trump’s speech
… congressional speech Tuesday night. She credits an experimental stem cell treatment with giving her new hope for her health and her future – a newfound hope that also caught attention of Republican Rep. Pete Olson. Olson, who represents Texas’ 22nd …
First Cancer Patient Treated In Phase I/II Trial of ApoGrafta
Cellect Biotechnology Ltd. , a developer of stem cells selection technology, today announces that it has treated the first blood cancer patient in the recently initiated Phase I/II trial of its stem cell technology ApoGraftTM. The trial is intended to assess the Cellect ApoGraftTM process which is designed to prevent Graft-versus-Host Disease , a common complication associated with stem cell transplant in which the transplanted immune cells attack the recipient’s body cells and organs.
BioRestorative Therapies Receives FDA Clearance to Initiate Phase 2…
BioRestorative Therapies, Inc. , a life sciences company focused on stem cell-based therapies, today announced that it has received clearance by the U.S. Food and Drug Administration to commence a Phase 2 clinical trial using its lead cell therapy candidate, BRTX-100, to treat chronic lower back pain due to degenerative disc disease related to protruding/bulging discs. The Phase 2 clinical trial is a 72 patient, randomized, double-blind, controlled, multi-center study designed to evaluate safety and efficacy of a single dose of BRTX-100 in treating chronic lower lumbar disc disease.
Kiadis Pharma issues clinical and regulatory progress update on ATIR101a and ATIR201a
… cell transplantation (HSCT) in blood cancer. Following regulatory approval from the national authority in Canada (Health Canada), the Company is pleased to announce the initiation of its randomized, controlled, transatlantic Phase III trial with …
Global Stem Cell Therapy Market to Showcase a CAGR of 37% Through 2021: Technavio
… organizations, due to the realization of the importance of regenerative medicine .” The US National Institute of Health , a major funding government organization invested approximately USD 1.5 billion in stem cell research projects in 2016. …
Cyclophosphamide vs salvage chemotherapy plus G-CSF as…
Autologous hematopoietic stem cell transplantation is the standard treatment option for multiple myeloma and relapsed non-Hodgkin’s lymphoma patients. 2 Chemo-mobilization success depends on the patient’s age, apheresis timing, chemotherapy and immunomodulatory regimens as well as chemotherapy-related adverse events .
First stem cell study could lead to development of therapy to reduce inflammation caused by CF
A 39-year-old man with cystic fibrosis made history by becoming the first person to receive human adult stem cells in a new research study that researchers hope will someday lead to the development of a therapy to reduce the inflammation and infection caused by CF. The pioneering subject in the study is Bob Held from Alliance, Ohio, who on Jan. 26 received an infusion of cells called allogeneic human mesenchymal stem cells , adult stem cells collected from the bone marrow of healthy volunteers.
Islets from rat-grown mouse pancreases can help reverse disease in diabetic mice
Mouse pancreases grown in rats generate functional, insulin-producing cells that can reverse diabetes when transplanted into mice with the disease, according to researchers at the Stanford University School of Medicine and the Institute of Medical Science at the University of Tokyo. The recipient animals required only days of immunosuppressive therapy to prevent rejection of the genetically matched rather than lifelong treatment.
Islets from rat-grown mouse pancreases can help reverse disease in diabetic mice
Mouse pancreases grown in rats generate functional, insulin-producing cells that can reverse diabetes when transplanted into mice with the disease, according to researchers at the Stanford University School of Medicine and the Institute of Medical Science at the University of Tokyo. The recipient animals required only days of immunosuppressive therapy to prevent rejection of the genetically matched rather than lifelong treatment.
Scientist Alan Mackay-Sim is Australian of the Year 2017
Australian of the Year 2017 is Alan Mackay-Sim: Scientist whose stem cell research is helping to repair damaged spinal cords wins national award Biomedical scientist Alan Mackay-Sim, whose research has been hailed ‘more impressive than man walking on the moon’, has been named the 2017 Australian of the Year. The Queensland-based professor has dedicated his life to pioneering stem cell research and its use in repairing damaged spinal cords, including helping to restore mobility in a quadriplegic man.
Study finds cutting calories may help monkeys live longer
A 2009 image of rhesus monkeys in a landmark study of the benefits of caloric restriction. The then 27-year-old monkey on the left was given a diet with fewer calories while the 29-year-old monkey on the right was allowed to eat as much as it liked.A new study of the effects of a restricted diet reinforces the idea that reducing caloric intake has health benefits that can extend lifespan.
Cell-Free Embryonic Stem Cell Extract-Mediated Derivation of…
The oocyte-independent source for the generation of pluripotent stem cells is among the ultimate goals in regenerative medicine. We report that on exposure to mouse embryonic stem cell extracts, reversibly permeabilized NIH3T3 cells undergo dedifferentiation followed by stimulus-induced redifferentiation into multiple lineage cell types.
Flood of News Presents Buying Opportunity
… 5 million and 6 million patients. Beyond the FDA, word just came in from the Paul Ehrlich Institute, Germany’s health regulator, that the same trial could begin enrollment there. Though the trial will be enrolling 250 patients globally, approval is …
Cellect Receives Patent Notice of Allowance from US Patent &…
Cellect Biotechnology Ltd. , a developer of stem cells isolation technology, announces today that it has received a formal notice of allowance around a key method of treatment patent from the United States Patent & Trademark Office. The allowed claims relate to the engineering of regulatory immune cells with enhanced apoptotic activity to be used for immunomodulation for treating or preventing immune related disorders.
Research suggests the stem cells in our teeth can be energized to fill in chips, cracks, and cavities
The stem cells in our teeth can be energized to fill in chips, cracks, and cavities, researchers say, and the findings could one day possibly make dental cement obsolete. The work has been conducted just in mice so far, but the research , published Monday in the journal Scientific Reports, highlights a way to motivate stem cells to repair tooth defects at a scale they normally can’t, with a drug that already has some safety testing behind it.
All my children call the centre ‘Our Maggie’s’
But last year the father-of-five discovered that he is also one in 500, after being diagnosed with a rare blood cancer called mantle cell lymphoma. Before his diagnosis in November, Andrew was the fittest he had been in years, after giving up booze and losing three stone through his passion for cycling.
Postdoctoral Fellow Positions Available
Postdoctoral fellow positions in neuroscience are available at the Department of Neurosurgery in the State University of New York Upstate Medical University in the . We are looking for highly motivated postdocs with experience in both in vivo and in vitro to join our research team for performing US federal government funded research projects.
Stem cell transplant is next challenge for Maine toddler fighting cancer
… has missed at work during the past five months, expenses are adding up even though the Arndts are covered by health insurance. To help offset the lost income, as well as trips back and forth to Portland and Boston, parking, meals and other expenses, …
Stem cell ‘mini-brain’ very similar to real brain, study finds
… as schizophrenia . Ecker and team compared their results to age-matched real tissue from the National Institutes of Health (NIH) NeuroBioBank and other 2-D brain model data. Although COs have been grown in laboratories for three years now, it was …
Stem cells give scientists a new window into the biology of a rare disease
Today, Stanford pediatric cardiologist Marlene Rabinovitch , MD, and her team published new research that advances their quest to understand a serious – and very puzzling – lung disease. They’re studying pulmonary arterial hypertension , which frequently leads to heart failure.
Scientists use stem cells to restore testosterone
… and deep vein thrombosis . In fact, in 2014, the United States Food and Drug Administration, in collaboration with Health Canada, mandated that manufacturers add a warning of these risks on all testosterone products. New stem cell research suggests …
Local nonprofit makes $100,000 commitment to Advocate Children’s Hospital
Andrew Smialek was just 14 years old when he was diagnosed with Hodgkin lymphoma. He spent his high school years and first year of college undergoing chemotherapy, as well as stem cell and bone marrow transplants.
Three parents, 1 baby – how does that work, in theory and practice?
This decision was taken 2 weeks after an independent expert scientific panel convened by HFEA published its fourth review of the safety and efficacy of mitochondrial donation. A “three-parent baby” is born after faulty bits of the mother’s DNA are replaced by those taken from a healthy donor.