Antony Blinken says US has been ‘engaged in intense diplomacy’ as the region braces for attacks from Iran and its allies

It has just gone 2pm in Jerusalem. If you’re just joining us, here are the day’s developments:

The United States has communicated to Iran and Israel that conflict in the Middle East must not escalate, secretary of state Antony Blinken said. The Middle East is bracing for a possible new wave of attacks by Iran and its allies after last week’s killing of senior members of militant groups Hamas and Hezbollah.

The Israeli military has issued new evacuation orders for an area in northern Gaza that was heavily bombed at the start of the war some 10 months ago. The IDF said it would respond to a Hamas rocket attack from the Beit Hanoun area the day before and urged residents to relocate to Gaza City, large areas of which have been destroyed.

More than 39,677 Palestinians have been killed and 91,645 have been injured in Israel’s military offensive in Gaza since Oct. 7, the health ministry in Hamas-run Gaza said in a statement on Wednesday.

Protesters have disrupted an Israeli supreme court hearing about a shadowy military facility where Israel has held Palestinian detainees throughout the war in Gaza. The protesters yelled “Shame!” as the attorney for a number of Israeli human rights groups argued that the Sde Teiman facility should be closed permanently over repeated allegations of detainee abuse. An Associated Press investigation into the facility, as well as others by rights groups, found detainees endured abysmal conditions there.

The assassination of a Hamas leader in Tehran humiliated Iran’s leaders, dashed hopes of a ceasefire and left the heavily armed nations of the Middle East moving inexorably closer to an all-out war they all claim not to want

If Iran’s newly elected president, Masoud Pezeshkian, was hoping for a honeymoon period after his inauguration last week, he must be sadly disappointed. Less than 12 hours after Pezeshkian was sworn in, an explosion, reportedly caused by a remotely controlled bomb, shook an Islamic Revolutionary Guard Corps (IRGC) compound in central Tehran. The target: Ismail Haniyeh, Hamas’s political leader, an honoured guest at the inauguration, and one of the Middle East’s most wanted. The bomb under the bed killed Haniyeh instantly. Honeymoon over.

Pezeshkian was the surprise winner of last month’s presidential election. Edging out a conservative hardliner favoured by Ayatollah Ali Khamenei, Iran’s supreme leader, he promised to repair tattered ties with the US and Europe. Many hoped his victory would herald a more open, more progressive era and defuse social tensions, especially over the enforced wearing of the hijab, which triggered huge unrest under his predecessor, Ebrahim Raisi.