Pitt researchers uncover genetic marker that may predict drug response in many cancer types

Researchers at the University of Pittsburgh School of Medicine have uncovered a novel genetic mechanism of thyroid cancer, as well as a marker that may predict response to a particular class of drugs, not just in patients with thyroid cancer, but in those with many other types of cancer as well. The new findings were published in Proceedings of the National Academy of Sciences .

Scientists identify novel mutations in bacteria that promote evolution of antibiotic resistance

Scientists from the Broad Institute of MIT and Harvard in Cambridge, Massachusetts, have identified novel mutations in bacteria that promote the evolution of high-level antibiotic resistance. The findings, published in eLife , add to our understanding of how antibiotic resistance develops, which the team says is crucial for maintaining the effectiveness of both existing and future drugs.

Research may show new ways to repress inflammation at outset

Researchers at the University of Tubingen, working with colleagues in other parts of Germany and in the United States, have identified an enzyme as a kind of biological gauge regulating inflammation in the human body. Professor Alexander Weber of the Interfaculty Institute of Cell Biology says the enzyme – Bruton’s tyrosine kinase or BTK – is switched on when an inflammation occurs in the body, playing a key role in the inflammation’s subsequent development.

Change of mammographic density predicts the risk of contralateral…

IntroductionMammographic density is a strong risk factor for breast cancer, but it is unknown whether density at first breast cancer diagnosis and changes during follow-up influence risk of non-simultaneous contralateral breast cancer . Methods: We collected mammograms for CBC-patients and unilateral breast cancer patients , individually matched on age and calendar period of first breast cancer diagnosis, type of adjuvant therapy and length of follow-up .

Healthy Homes Happy Families Expo offers practical ideas for families from local experts

L to R: Children’s health advocate Kim Spencer has invited Dr. Ramon Ramos, Dr. Tassie Hargrove and Chelsea Dye along with other local wellness experts to share their wisdom at the Healthy Homes Happy Families Expo on Saturday, Feb. 25. ASTHMA, behavior issues, depression, diabetes, eczema, food allergies, obesity…there’s an alphabet soup of negative health conditions that are becoming increasingly more common in childhood. The Journal of American Medicine reports that chronic illness in American kids and teens has more than doubled since the 1990s, adding higher numbers to the pot: One in six has a developmental disability.

Dental Elevator and Luxator Market: Industry Analysis, Trend, Demand and Global Forecast to 2024

PUNE, MAHARASHTRA , INDIA , February 21, 2017 / EINPresswire.com / — Dental Luxator and Elevator Market: Dental luxator Periotome are specially designed periodontal ligament knifes with a fine tapering blade that compresses the aveolar, cuts the membrane to enable the dentist to gently ease the tooth from its socket. The extraction operation may be performed with the minimum amount of tissue damage.

Cell Medica: Lead Cancer Immunotherapy Candidate Receives FDA Fast Track Designation

Cell Medica, a leader in developing cellular immunotherapy for the treatment of cancer, today announced the U.S. Food and Drug Administration has granted Fast Track designation to its lead oncology product CMD-003 for patients with relapsed/refractory lymphoma and post-transplant lymphoproliferative disease associated with the oncogenic Epstein Barr virus . CMD-003, also known as baltaleucel-T, is an investigational therapy in which the patient’s T cells are activated to kill malignant cells expressing EBV antigens.

Keighley Town Council issues warning to fend off bird flu threat

OUTBREAKS of avian flu creeping closer to Keighley have prompted Keighley Town Council’s allotments officer to issue a warning to allotment holders who keep poultry or other captive birds. Lee Senior said the council is aware of instances of this disease as close as Gargrave and Addingham , adding that the town council is continuing to take advice from the Government’s Department for Environment, Food & Rural Affairs.

Teenager, 18, with Tourette’s films himself using a hose

Teenager, 18, with Tourette’s films himself swearing constantly while using a hose to highlight his struggle with physical and verbal tics A teenager with Tourette’s has revealed footage showing how the syndrome makes him struggle with simple everyday tasks like using a hose. Lewis Nickell, 18, asked his brother to film him using the water jet in their garden in Bangor, Northern Ireland, to highlight his struggle with physical and vocal tics.

France to cull 600,000 ducks

Paris: French authorities will cull 600,000 ducks in the Landes region due to bird flu, the Agriculture Minister said on Tuesday. Speaking about the radical measure in an interview, Stephane Le Foll said the virus had spread from the east to the west of Landes and the goal was to try and stabilise the situation, Efe news reported.

SW China province reports two H7N9 cases

Two human H7N9 avian flu cases were reported Tuesday in southwest China’s Sichuan Province, bringing the number of infections in the province this year to eight, including two fatalities. Both patients had contact with live poultry and no symptoms have been observed among those in close contact with them, according to the provincial health and family planning commission.

Story of Courage: The Update on Brittney Beadle

She’s the courageous young cancer patient who stuck in the hearts of many in our area when she first shared her journey nearly two years ago. Brittney Beadle of Taylor first talked with Newswatch 16’s Ryan Leckey shortly after being diagnosed with breast cancer and had a double mastectomy at the age of 18. A year later , in 2016, Ryan visited Brittney again when she got the good news that her cancer was in remission.

Antiviral Therapeutics Technologies, Markets and Companies Report…

Dublin, Feb. 21, 2017 — Research and Markets has announced the addition of Jain PharmaBiotech’s new report “Antiviral Therapeutics – Technologies, Markets and Companies” to their offering. This report reviews the current state-of-art of antiviral approaches including vaccines, pharmaceuticals and innovative technologies for delivery of therapeutics.

Cardiovascular Drug Delivery Report 2017-2026: Focus on Technologies, …

Dublin, Feb. 21, 2017 — Research and Markets has announced the addition of Jain PharmaBiotech’s new report “Cardiovascular Drug Delivery – Technologies, Markets and Companies” to their offering. Drug delivery to the cardiovascular system is different from delivery to other systems because of the anatomy and physiology of the vascular system; it supplies blood and nutrients to all organs of the body.

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A BLIND World War Two veteran from Stafford has been formally presented with France’s highest honour for his part in the liberation of France. Rowland Edwards, 93, received the Chevalier de l’Ordre National de la Legion d’Honneur during a special ceremony at the National Memorial Arboretum.

Obamacare has staying power

… the trigger? That’s a rhetorical question, of course. Republicans see that they have two choices: They can snatch health insurance away from millions of people, or they can replace Obamacare with something that looks suspiciously like …

Mum shares heartbreaking photo of son in nappy

Drake’s mother knows people will question her decision to share the powerful picture of her 10-year-old son in a nappy. Picture: Facebook FOR many people, their first reaction when looking at this gut-wrenching photo would be: “Why would on earth any parent in their right mind share this image to the world?” The powerful picture, as featured on Kidspot , shows Drake, 10, in the bathroom wearing a pull-up nappy.