Research may show new ways to repress inflammation at outset

Researchers at the University of Tubingen, working with colleagues in other parts of Germany and in the United States, have identified an enzyme as a kind of biological gauge regulating inflammation in the human body. Professor Alexander Weber of the Interfaculty Institute of Cell Biology says the enzyme – Bruton’s tyrosine kinase or BTK – is switched on when an inflammation occurs in the body, playing a key role in the inflammation’s subsequent development.

Research findings could lead to effective repair therapies for peripheral nerve damage

Research published today, 30th January 2017 online in the Journal of Cell Biology , has for the first time identified how a bodily protein allows nerves of the peripheral nervous system to repair following injury. The findings, discovered by research neuroscientists at Plymouth University Peninsula Schools of Medicine and Dentistry and funded by the Medical Research Council, could lead to effective repair therapies for those who have suffered peripheral nerve damage in trauma cases or perhaps via battlefield injuries.

Murine Study Finds Potential Boost for Ovarian Cancer Drug Olaparib

Researchers from the Chinese Academy of Sciences have discovered that the metabolic enzyme phosphoglycerate mutase 1 helps cancer cells repair their DNA and found that inhibiting PGAM1 sensitizes tumors to the cancer drug Olaparib . Their findings in the study ” Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells ,” which has been published in The Journal of Cell Biology , suggest that this FDA-approved ovarian cancer medicine has the potential to treat a wider range of cancer types than currently indicated.

Postdoctoral Fellow Positions Available

Postdoctoral fellow positions in neuroscience are available at the Department of Neurosurgery in the State University of New York Upstate Medical University in the . We are looking for highly motivated postdocs with experience in both in vivo and in vitro to join our research team for performing US federal government funded research projects.