A 39-year-old man with cystic fibrosis made history by becoming the first person to receive human adult stem cells in a new research study that researchers hope will someday lead to the development of a therapy to reduce the inflammation and infection caused by CF. The pioneering subject in the study is Bob Held from Alliance, Ohio, who on Jan. 26 received an infusion of cells called allogeneic human mesenchymal stem cells , adult stem cells collected from the bone marrow of healthy volunteers.
Category: Health
Chair, Department of Medical Biophysics, University of Toronto
Applications are invited for the position of Chair of the Department of Medical Biophysics in the Faculty of Medicine at the University of Toronto. The successful candidate must be eligible for a status-only appointment at the rank of Full Professor.
Hypoxia in primary tumors influences dormant DTCs that evade cancer therapy, study shows
In a first of its kind study, Mount Sinai researchers have discovered the conditions by which specific signals in primary tumors of head and neck and breast cancers, pre-program cancer cells to become dormant and evade chemotherapy after spreading. Their findings, published in the January 31, 2017 issue of Nature Cell Biology and featured on the cover, could lead to new drug development, treatment options and transform the way doctors care for cancer patients to treat metastatic disease.
Thata s not true: Stand guard against interneta s fake news virus
“Fear of foreigners” headlines from the 1920s warned Americans about the peril of alien invaders from Europe. During 1941, our country declared war against Japan and hysteria swept across the nation; truth became the first casualty of war and anyone who “looked” like the enemy became the enemy with sightings of “Jap” planes over our Valley.
Life in the slow lane: Why supermarkets should rethink the need for speed
As a full-time parent to two young children, Aaron Saltzman’s ‘real’ day job provides practical, hands-on experience for the position of CBC’s Senior Reporter, Consumer Affairs. Nearly 20 years experience in television, radio and online news also helps.
Space-age inventions we use daily
Gordon Ramsay is not someone you usually associate with the space age. But there he was last week, pictured working out on a Nasa-inspired 30 000 treadmill.
Johns Hopkins researchers create mature cardiomyocytes in the laboratory from stem cells
Generating mature and viable heart muscle cells from human or other animal stem cells has proven difficult for biologists. Now, Johns Hopkins researchers report success in creating them in the laboratory by implanting stem cells taken from a healthy adult or one with a type of heart disease into newborn rat hearts.
Scientists create mature heart muscle cells from stem cells
The mature heart muscle cells were created by implanting stem cells from a healthy adult or one with a type of heart disease into newborn rat hearts. The host hearts then give biological signals and chemistry necessary for the implanted immature heart muscle cells to overcome a developmental blockage that usually stops growth.
Scientists create mature heart muscle cells from stem cells
The mature heart muscle cells were created by implanting stem cells from a healthy adult or one with a type of heart disease into newborn rat hearts. The host hearts then give biological signals and chemistry necessary for the implanted immature heart muscle cells to overcome a developmental blockage that usually stops growth.
Scientists Cure Mice of Diabetes Using Cells Grown Inside Rats
In a process that could transform organ transplantation, scientists in Japan and the U.S. have reportedly cured mice of diabetes by transplanting mouse cells grown in rats . The study has been published in the journal Nature .
Rat-grown mouse pancreases help reverse diabetes in mice
Mouse pancreases grown in rats generate functional, insulin-producing cells that can reverse diabetes when transplanted into mice with the disease, according to researchers at the Stanford University School of Medicine and the Institute of Medical Science at the University of Tokyo. The recipient animals required only days of immunosuppressive therapy to prevent rejection of the genetically matched rather than lifelong treatment.
Researchers reveal ‘alien’ life using synthetic DNA
Researchers at the Scripps Research Institute in La Jolla, California, introduced DNA molecules not found in nature to a common bacterium The E. coli bugs are able to grow and reproduce as normal despite containing two extra letters in their genetic code In the future the research could lead to creation of microbes capable of manufacturing entirely new proteins that could be used in medicine Some people are worried that the rapid advance of ‘synthetic biology’ could lead to the worrying prospect of new life-forms escaping from labs The modified E.coli bacteria was made by scientists who introduced DNA molecules not found in nature to a common bacterium.
What Makes The IPhone Special
When you want to uncover your iPhone, there are a few methods to move about doing so. If you’ve been faithful to your contract, you could be able to do so by way of your carrier network or perhaps by way of a network-authorized service.
Samsung Pills
Consumer Intelligence Research Companions released analysis associated with the results of its study on cellular phone operating techniques and brands for the work schedule quarter that ended Summer 30, 2015. Overall, with ANDROID OS and Microsoft Exchange Server hosting from a credit card applicatoin service company, companies can add the Android Program to their worker marketing communications options confidently.
Protein-Induced Pluripotent Stem Cells Ameliorate Cognitive…
Protein-Induced Pluripotent Stem Cells Ameliorate Cognitive Dysfunction and Reduce AI2 Deposition in a Mouse Model of Alzheimer’s Disease. : Transplantation of stem cells into the brain attenuates functional deficits in the central nervous system via cell replacement, the release of specific neurotransmitters, and the production of neurotrophic factors.
The proliferative and chronotropic effects of Brillantaisia nitens…
Brillantaisia nitens Lindau leaves are commonly used in traditional medicine in Africa for the treatment of many disorders including heart diseases and malaria. In this study, we therefore evaluated the effect of the methylene chloride/methanol leaf extract of Brillantaisia nitens on the proliferation of mouse pluripotent stem cells and their cardiomyocyte derivatives.
Why are Canadians over 35 barred from signing up to donate bone marrow?
Bone marrow is the body’s production plant for blood, and donated marrow is sometimes the only treatment for patients with leukemia. A few years ago, Yael Heffer wanted to get on the Canadian bone marrow donor list.
Cell-Free Embryonic Stem Cell Extract-Mediated Derivation of…
The oocyte-independent source for the generation of pluripotent stem cells is among the ultimate goals in regenerative medicine. We report that on exposure to mouse embryonic stem cell extracts, reversibly permeabilized NIH3T3 cells undergo dedifferentiation followed by stimulus-induced redifferentiation into multiple lineage cell types.
UC San Diego researchers receive CIRM grants to advance studies on Zika virus and cancer
The Independent Citizens Oversight Committee of the California Institute for Regenerative Medicine has approved a pair of $2 million awards to University of California San Diego School of Medicine researchers to advance studies of new treatments for Zika virus infections and the use of stem cell-derived natural killer cells to target ovarian cancer and other malignancies. The Zika virus is linked to increased birth defects, most notably microcephaly – newborns with smaller than expected heads and abnormal brain development.
Soft Robot Helps the Heart Beat
Harvard University and Boston Children’s Hospital researchers have developed a customizable soft robot that fits around a heart and helps it beat, potentially opening new treatment options for people suffering from heart failure. The soft robotic sleeve twists and compresses in synch with a beating heart, augmenting cardiovascular functions weakened by heart failure.
#Biotech #Stock Additions: $INVA, $KTOV, $MSTX, $NK, $OPNT, $HSGX
January 20, 2017 Investorideas.com, a global news source and investor resource covering actively traded sectors announces this week’s additions to its membership global stock directories in biotech, marijuana-hemp, mining, tech and water. Biotech stock additions cover stem cell, life sciences, and biotech companies focused on pain management related to osteoarthritis & hypertension, respiratory disease, HFpEF , cancer, musculoskeletal diseases and addiction and substance abuse, including an inhalable overdose treatment.
p62/SQSTM1 enhances breast cancer stem-like properties by stabilizing MYC mRNA
467 Zhongshan Road, Shahekou District, Dalian, Liaoning 116000, China. E-mail: dlzhaozw@163.com Aberrant p62 overexpression has been implicated in breast cancer development.
Teaching Computers to Recognize Sick Guts: Machine-Learning and the Microbiome
A new proof-of-concept study by researchers from the University of California San Diego succeeded in training computers to “learn” what a healthy versus an unhealthy gut microbiome looks like based on its genetic makeup. Since this can be done by genetically sequencing fecal samples, the research suggests there is great promise for new diagnostic tools that are, unlike blood draws, non-invasive.
Diabetes: Stimulating bone stem cells may improve fracture repair
Researchers have discovered a protein that stimulates bone stem cells in mice with diabetes so that the animals heal better after a fracture. They suggest that this could lead to a new treatment to improve bone repair in people with diabetes.
Biden’s Cancer Moonshot Draws on Aussie Nobel-Winning Expertise
U.S. Vice President Joe Biden arrived in Melbourne last July with his granddaughters in tow. Bypassing sporting stadiums and race-car tracks, Biden’s first official stop in the world’s sporting capital was to open a A$1 billion cancer center.
Stem cells could one day replace the work of dental fillings, study shows
The stem cells in our teeth can be energized to fill in chips, cracks, and cavities, researchers say, and the findings could one day make dental cement obsolete. The work has been conducted just in mice so far, but the research , published Monday in the journal Scientific Reports , highlights a way to motivate stem cells to repair tooth defects at a scale they normally can’t, with a drug that already has some safety testing behind it.
Secretive Biotech Unicorn Moderna Unveils Pipeline, Financials
Moderna Therapeutics Inc., one of the best-funded private biotechnology companies in the U.S., unveiled its long-secret research and development pipeline on Monday, including experimental vaccines, cancer treatments and a cardiovascular therapy. The Cambridge, Massachusetts-based startup has about $1.3 billion in cash on hand from investors, pharmaceutical partners and government grants, according to a presentation Monday at the J.P.Morgan Chase & Co.
IBM sets US patent record with cognitive computing, cloud and AI inventions
Inventions in AI, cloud and cyber security saw IBM best the likes of Samsung and Google to take the top patent spot in 2016. Pushes in AI, cognitive computing, cloud and cyber security saw IBM notch up 8,088 US patents, which works out to 22 patents per day in 2016.
What to expect at work in 2017: Fewer raises, different perks
Like so many things for the year ahead, many changes coming to the workplace are surrounded by questions. If Congress repeals or replaces the Affordable Care Act, what will that mean for employee health insurance? Will companies still have to publish the potentially embarrassing CEO-to-worker pay ratio, or will that part of the Dodd-Frank act be repealed, too? Will my employer or state join the bandwagon of those who have recently expanded paid parental leave? The answers to many of these questions are unknown.
US cancer deaths down 25 percent since 1991
Fewer Americans are dying from the second biggest killer in the U.S.: cancer. New numbers from the American Cancer Society show from 1991 to 2014, the cancer death rate has dropped by a quarter.
US cancer deaths down 25 percent since 1991
Winter Weather Advisory issued January 6 at 11:01AM CST expiring January 6 at 5:00PM CST in effect for: Choctaw, Haskell, Latimer, LeFlore, Pittsburg, Pushmataha Winter Weather Advisory issued January 6 at 9:59AM CST expiring January 6 at 6:00PM CST in effect for: McCurtain Hard Freeze Warning issued January 6 at 4:50AM CST expiring January 7 at 9:00AM CST in effect for: McCurtain Fewer Americans are dying from the second biggest killer in the U.S.: cancer. New numbers from the American Cancer Society show from 1991 to 2014, the cancer death rate has dropped by a quarter.
Miniature brain and skull found inside 16-year-old girl’s ovary
A tumour containing a miniature brain has been found growing on the ovary of a 16-year-old girl in Japan. The 10-centimetre-wide tumour was discovered when the girl had surgery to remove her appendix.
Skin Cancer Breakthrough 2017: Melanoma Spread Reduced By Up To 90% With New Man-Made Compound
Skin cancer is the most common form of cancer is the world, and although melanoma is a more rare form, it is also the most deadly . New research from Michigan State University may soon change this.
Researchers develop first non-human primate X-SCID models using genome editing techniques
Researchers affiliated with the K awasaki IN novation G ateway at SKYFRONT, have successfully generated the first ever non-human primate X-SCID models by using two genome editing techniques. The findings were published in Cell Stem Cell, July 2016.
First interactive 3D video hologram displays live footage of internal organs
UK scientists are developing an interactive holographic video created from an MRI or CT scan that can display live footage of internal organs in front of a user where features can be rotated, enlarged, and isolated, delivering a breakthrough in medical imaging and education. Popping in to your local hospital may be much more revealing in as little as three years thanks to engineers at Holoxica Limited, who have invented a moving 3D video hologram.
Demonetization as Indian tragedy: Modi silent on specifics of black money : The Canadian National Newspaper
For several months, we, at The Canadian, have been documenting complaints against Dr. Jerry Tenenbaum which subvert the integrity of OHIP specifically and Canada’s public healthcare system in general. On 30 December 2016, the Toronto Star further documented how the province’s 12 top-billing doctors – who received payments of between $2 million and $7 million in one year – are overcharging the Ontario Health Insurance Plan.
CES 2017: From new smart TVs to sleep tech, here’s what to expect
The eyes of the tech world will be firmly fixed on Las Vegas when the Consumer Electronics Show kicks off next week. CES 2017 also marks the event’s 50th anniversary and news.com.au ‘s technology editor Matthew Dunn will be there to take in all the action, and there’s plenty to look forward to.
Rats and cockroaches among thousands of pests found in NHS hospitals
Thousands of pests including cockroaches and rats have been found in NHS hospitals in each of the last five years as the cost of tackling them has spiralled, new figures show. Data obtained by the Press Association under Freedom of Information laws shows there were nearly 5,000 pest control call-outs by NHS trusts to hospitals in England in 2015/16 – equivalent to around 13 a day.
Pluristem Therapeutics And New York Blood Center To Collaborate In…
Pluristem Therapeutics And New York Blood Center To Collaborate In Evaluating PLX-R18 As An Adjuvant Therapy To Umbilical Cord Blood Transplantation, Winning $900,000 Funding From BIRD Prior research has suggested that PLX-R18 helps cord blood cells to engraft more rapidly and effectively Grant of $900,000 from Israel-U.S. Binational Industrial Research and Development Foundation to fund the research Constitutes a 3rd potential hematologic indication for PLX-R18 HAIFA, Israel, Dec. 27, 2016 — Pluristem Therapeutics Inc. , a leading developer of placenta-based cell therapy products, today announced that it will collaborate with the New York Blood Center on preclinical studies of its Placental eXpanded -R18 cells to enhance the efficacy of umbilical cord blood transplantation.
Stem cells give Stanford scientists a new window into the biology of a rare disease
Today, Stanford pediatric cardiologist Marlene Rabinovitch , MD, and her team published new research that advances their quest to understand a serious – and very puzzling – lung disease. They’re studying pulmonary arterial hypertension , which frequently leads to heart failure.