Cell Therapy Report 2017-2026: Focus on Technologies, Markets and Companies – Profiles of 303 Companies with Tabulation of 292 Alliances Dublin, Feb. 03, 2017 — Research and Markets has announced the addition of Jain PharmaBiotech’s new report “Cell Therapy – Technologies, Markets and Companies” to their offering. This report describes and evaluates cell therapy technologies and methods, which have already started to play an important role in the practice of medicine.
Category: Stem Cell Research
Global Stem Cell Therapy Market to Showcase a CAGR of 37% Through 2021: Technavio
The research study covers the present scenario and growth prospects of the global stem cell therapy market for 2017-2021. To determine the market size, the study considers revenue generated from allogenic and autogenic stem cell therapies.
Human-pig hybrids might be unsettling. But they could save lives.
Scientists inject human stem cells into a pig blastocyst. A laser beam was used to perforate an opening to the outer membrane of the pig blastocyst to allow easy access of an injection needle delivering human iPS cells.
In vivo and in vitro stem cell function of c-kit- and Sca-1-positive murine hematopoietic cells.
To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document. c-kit is expressed on hematopoietic stem cells and progenitor cells, but not on lymphohematopoietic differentiated cells.
World’s First Stem-Cell Study for Cystic Fibrosis
A 39-year-old man with cystic fibrosis has made history by becoming the first person in the world to receive human adult stem cells in a new study that researchers hope will some day lead to the development of a therapy to reduce the inflammation and infection caused by CF. The study is being conducted at University Hospitals Rainbow Babies & Children’s Hospital in Cleveland, Ohio.
First stem cell study could lead to development of therapy to reduce inflammation caused by CF
A 39-year-old man with cystic fibrosis made history by becoming the first person to receive human adult stem cells in a new research study that researchers hope will someday lead to the development of a therapy to reduce the inflammation and infection caused by CF. The pioneering subject in the study is Bob Held from Alliance, Ohio, who on Jan. 26 received an infusion of cells called allogeneic human mesenchymal stem cells , adult stem cells collected from the bone marrow of healthy volunteers.
Louisville walks in solidarity with national March for Life
The pro-life prayer walk went through downtown Louisville and stopped for prayer at various locations before ending at the Cathedral of the Assumption. “I think everybody deserves a right to life,” said Amanda Ball, who drove three hours from Jackson County to be at the prayer walk.
Stem cell secretions may protect against glaucoma
A new study in rats shows that stem cell secretions, called exosomes, appear to protect cells in the retina, the light-sensitive tissue in the back of the eye. The findings, published in Stem Cells Translational Medicine , point to potential therapies for glaucoma, a leading cause of blindness in the United States.
Johns Hopkins researchers create mature cardiomyocytes in the laboratory from stem cells
Generating mature and viable heart muscle cells from human or other animal stem cells has proven difficult for biologists. Now, Johns Hopkins researchers report success in creating them in the laboratory by implanting stem cells taken from a healthy adult or one with a type of heart disease into newborn rat hearts.
Scientists create mature heart muscle cells from stem cells
The mature heart muscle cells were created by implanting stem cells from a healthy adult or one with a type of heart disease into newborn rat hearts. The host hearts then give biological signals and chemistry necessary for the implanted immature heart muscle cells to overcome a developmental blockage that usually stops growth.
Scientists create mature heart muscle cells from stem cells
The mature heart muscle cells were created by implanting stem cells from a healthy adult or one with a type of heart disease into newborn rat hearts. The host hearts then give biological signals and chemistry necessary for the implanted immature heart muscle cells to overcome a developmental blockage that usually stops growth.
Study of Gap Junctions in Human Embryonic Stem Cells.
To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document. Gap junctional intercellular communication has been described in different cell types including stem cells and has been involved in different biological events.
Gene expression of pluripotency determinants is conserved between mammalian and planarian stem cells.
Freshwater planaria possess extreme regeneration capabilities mediated by abundant, pluripotent stem cells in adult animals. Although planaria emerged as an attractive in vivo model system for stem cell biology, gene expression in neoblasts has not been profiled comprehensively and it is unknown how molecular mechanisms for pluripotency in neoblasts relate to those in mammalian embryonic stem cells .
Researcher’s bid to stop child-killing syndrome
An Auckland-based doctor’s ground-breaking research, involving lab-cultivated, living, beating heart cells, could land a blow against a major killer of Kiwi children. A new effort has been launched to keep Swedish paediatric cardiology expert Dr Annika Winbo’s pioneering work here in New Zealand.
Rat-grown mouse pancreases help reverse diabetes in mice
Mouse pancreases grown in rats generate functional, insulin-producing cells that can reverse diabetes when transplanted into mice with the disease, according to researchers at the Stanford University School of Medicine and the Institute of Medical Science at the University of Tokyo. The recipient animals required only days of immunosuppressive therapy to prevent rejection of the genetically matched rather than lifelong treatment.
The Life Sciences Report Asks If It Is Time to Go Long on BrainStorm Cell Therapeutics
BrainStorm Cell Therapeutics is a biopharmaceutical company developing adult stem cell-based therapies for a variety of neurodegenerative diseases such as amyotrophic lateral sclerosis , multiple sclerosis and Parkinson’s disease . The company’s NurOwnA technology is based on the use of mesenchymal stem cells , engineered ex vivo, to express increased amount of neurotrophic factors .
Protein-Induced Pluripotent Stem Cells Ameliorate Cognitive…
Protein-Induced Pluripotent Stem Cells Ameliorate Cognitive Dysfunction and Reduce AI2 Deposition in a Mouse Model of Alzheimer’s Disease. : Transplantation of stem cells into the brain attenuates functional deficits in the central nervous system via cell replacement, the release of specific neurotransmitters, and the production of neurotrophic factors.
The proliferative and chronotropic effects of Brillantaisia nitens…
Brillantaisia nitens Lindau leaves are commonly used in traditional medicine in Africa for the treatment of many disorders including heart diseases and malaria. In this study, we therefore evaluated the effect of the methylene chloride/methanol leaf extract of Brillantaisia nitens on the proliferation of mouse pluripotent stem cells and their cardiomyocyte derivatives.
Why are Canadians over 35 barred from signing up to donate bone marrow?
Bone marrow is the body’s production plant for blood, and donated marrow is sometimes the only treatment for patients with leukemia. A few years ago, Yael Heffer wanted to get on the Canadian bone marrow donor list.
Cell-Free Embryonic Stem Cell Extract-Mediated Derivation of…
The oocyte-independent source for the generation of pluripotent stem cells is among the ultimate goals in regenerative medicine. We report that on exposure to mouse embryonic stem cell extracts, reversibly permeabilized NIH3T3 cells undergo dedifferentiation followed by stimulus-induced redifferentiation into multiple lineage cell types.
Reprogramming mediated by stem cell fusion
Journal of Cellular and Molecular Medicine , Vol. 9, No. 2. , pp. 320-330, doi:10.1111/j.1582-4934.2005.tb00358.x To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document.
Dedifferentiation derived cells exhibit phenotypic and functional…
Journal of Cellular and Molecular Medicine , Vol. 14, No. 5. , pp. 1135-1145, doi:10.1111/j.1582-4934.2009.00765.x Differentiated epidermal cells can dedifferentiate into stem cells or stem cell-like cells in vivo.
UC San Diego researchers receive CIRM grants to advance studies on Zika virus and cancer
The Independent Citizens Oversight Committee of the California Institute for Regenerative Medicine has approved a pair of $2 million awards to University of California San Diego School of Medicine researchers to advance studies of new treatments for Zika virus infections and the use of stem cell-derived natural killer cells to target ovarian cancer and other malignancies. The Zika virus is linked to increased birth defects, most notably microcephaly – newborns with smaller than expected heads and abnormal brain development.
#Biotech #Stock Additions: $INVA, $KTOV, $MSTX, $NK, $OPNT, $HSGX
January 20, 2017 Investorideas.com, a global news source and investor resource covering actively traded sectors announces this week’s additions to its membership global stock directories in biotech, marijuana-hemp, mining, tech and water. Biotech stock additions cover stem cell, life sciences, and biotech companies focused on pain management related to osteoarthritis & hypertension, respiratory disease, HFpEF , cancer, musculoskeletal diseases and addiction and substance abuse, including an inhalable overdose treatment.
p62/SQSTM1 enhances breast cancer stem-like properties by stabilizing MYC mRNA
467 Zhongshan Road, Shahekou District, Dalian, Liaoning 116000, China. E-mail: dlzhaozw@163.com Aberrant p62 overexpression has been implicated in breast cancer development.
Athersys Subsidiary and Leading Animal Health Company Enter Into…
Athersys, Inc. announced today that through its Belgian subsidiary, ReGenesys BVBA , it has entered into an agreement with a global leader in the animal health business segment to evaluate the cell therapy technology for application in a non-disclosed animal health area. Under the terms of the agreement, ReGenesys will receive an initial payment in exchange for an exclusive period to evaluate the cell therapy technology with an option to negotiate for a license for the development and commercialization of the technology for this area.
Korea to invest W98.2b in upgrading biopharma evaluation guidelines
The South Korean government said Tuesday that it would invest 98.2 billion won in improving its evaluation guidelines for new biopharmaceutical products over the next 10 years. The plans came as part of the latest agenda set by a special pan-government biotechnology committee led by the Ministry of Science, ICT and Future Planning.
Blood stem cell donor meets the man whose life he helped save
The Oregon resident wasn’t improving despite regular chemotherapy treatments and instead was reliant on finding a perfect match to fight his blood cancer called myelodysplastic syndrome. More than 2,000 miles away, at Ohio University, Ethan Krafft had his cheek swabbed with a group of fellow business fraternity members for community service credit.
Way found to reprogram mouse embryonic stem cells
This undated photo provided by animal clone scientist Zhou Qi of the Institute of Zoology in Beijing shows the mouse Xiao Xiao or “Tiny” from the induced pluripotent stem cells in its three-month old. Two teams of Chinese researchers have created live mice from IPS cells, answering a lingering question about the developmental potential of the cells, according to a press release published online by Nature on July 23, 2009.
Scientists reprogram embryonic stem cells to expand their potential
Researchers from UC Berkeley have found a way to reprogram mouse embryonic stem cells so that they exhibit developmental characteristics resembling those of fertilized eggs, or zygotes. While typical embryonic stem cells are unable to make tissues like the placenta, which allow the embryo to communicate with the mother, blocking a microRNA unleashes the potential to make these extra-embryonic tissues .
Cell signalling pathways underlying induced pluripotent stem cell reprogramming.
Induced pluripotent stem cells, somatic cells reprogrammed to the pluripotent state by forced expression of defined factors, represent a uniquely valuable resource for research and regenerative medicine. However, this methodology remains inefficient due to incomplete mechanistic understanding of the reprogramming process.
Stem cells could one day replace the work of dental fillings, study shows
The stem cells in our teeth can be energized to fill in chips, cracks, and cavities, researchers say, and the findings could one day make dental cement obsolete. The work has been conducted just in mice so far, but the research , published Monday in the journal Scientific Reports , highlights a way to motivate stem cells to repair tooth defects at a scale they normally can’t, with a drug that already has some safety testing behind it.
The ethics of ‘Snowflake babies’: Is adoption the answer to unused frozen embryos?
They’re sometimes called “Snowflake” babies – children who were once frozen as embryos in a thin cane of liquid nitrogen. They were created when their biological parents used in vitro fertilization in their quest to conceive a child, and these embryos were the leftovers, the ones that didn’t get used.
OncoMed Announces Year-End Cash Balance and 2017 Outlook
OncoMed Pharmaceuticals Inc. , a clinical-stage company focused on discovering and developing novel anti-cancer stem cell and immuno-oncology therapeutics, today pre-announced its 2016 year-end cash balance and reviewed key anticipated events for 2017. OncoMed ended 2016 with approximately $184.6 million in cash.
Researchers develop first non-human primate X-SCID models using genome editing techniques
Researchers affiliated with the K awasaki IN novation G ateway at SKYFRONT, have successfully generated the first ever non-human primate X-SCID models by using two genome editing techniques. The findings were published in Cell Stem Cell, July 2016.
Dodeca-CLE Peptides as Suppressors of Plant Stem Cell Differentiation
To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document. In plants and animals, small peptide ligands that signal in cell-cell communication have been suggested to be a crucial component of development.
a Plant Peptide Encoded by CLV3 Identified by in Situ Maldi-Tof MS Analysis
To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document. The Arabidopsis CLAVATA3 gene encodes a stem cell-specific protein presumed to be a precursor of a secreted peptide hormone.
Postdoctoral Fellow Positions Available
Postdoctoral fellow positions in neuroscience are available at the Department of Neurosurgery in the State University of New York Upstate Medical University in the . We are looking for highly motivated postdocs with experience in both in vivo and in vitro to join our research team for performing US federal government funded research projects.
Zacks Investment Research Lowers ImmunoCellular Therapeutics Ltd. (IMUC) to Sell
According to Zacks, “ImmunoCellular Therapeutics, Ltd. operates as a development stage company with primary focus on the development and commercialization of new therapeutics to fight cancer using the immune system. Its product candidate portfolio includes cellular immunotherapies targeting cancer and cancer stem cell antigens, peptide based immunotherapies targeting cancer stem cells, and monoclonal antibodies to diagnose and treat several different cancers.
Pluristem Therapeutics And New York Blood Center To Collaborate In…
Pluristem Therapeutics And New York Blood Center To Collaborate In Evaluating PLX-R18 As An Adjuvant Therapy To Umbilical Cord Blood Transplantation, Winning $900,000 Funding From BIRD Prior research has suggested that PLX-R18 helps cord blood cells to engraft more rapidly and effectively Grant of $900,000 from Israel-U.S. Binational Industrial Research and Development Foundation to fund the research Constitutes a 3rd potential hematologic indication for PLX-R18 HAIFA, Israel, Dec. 27, 2016 — Pluristem Therapeutics Inc. , a leading developer of placenta-based cell therapy products, today announced that it will collaborate with the New York Blood Center on preclinical studies of its Placental eXpanded -R18 cells to enhance the efficacy of umbilical cord blood transplantation.