Possible link between J&J Covid vaccine and rare blood clots, EU regulator finds

Watchdog says benefits outweigh risks but that warning should be added to product information

Europe’s medicines regulator has found a possible link between Johnson & Johnson’s coronavirus vaccine and rare cases of unusual blood clotting disorders it said were “very similar” to those that had occurred with the AstraZeneca shot.

The European Medicines Agency (EMA) on Tuesday recommended a warning should be added to the vaccine’s product information, but stressed that the benefits of the shot – whose rollout was paused last week in Europe and the US – outweighed its risks.

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UK in drive to develop drugs to take at home to ‘stop Covid in its tracks’

Ministers announce taskforce to ‘supercharge’ search for antiviral treatments to roll out as soon as autumn

People with mild Covid-19 could take a pill or capsule at home to prevent the illness turning serious and requiring hospital treatment, under government plans to fast-track development of treatments for the disease.

The government is launching an antivirals taskforce to find at least two drugs by the autumn that people can take to stop coronavirus in its tracks and speed up recovery from it.

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Add India to UK travel ban list to stop Covid variant, urges scientist

Indian coronavirus variant has potential to ‘scupper’ lockdown easing, says professor of immunology

India should be placed on the UK’s “red list” for travel after the discovery of a new coronavirus variant, according to a leading scientist.

Prof Danny Altmann, from Imperial College London, said it was “mystifying” and “confounding” that those flying in from the country were not required to stay in a hotel.

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UK church leaders warn against ‘dangerous’ vaccine passport plans

Hundreds of Christian clergy say proposal could ‘bring about the end of liberal democracy’

Hundreds of UK church leaders have told the prime minister that plans to use vaccine passports for entry into venues is “one of the most dangerous policy proposals ever to be made in the history of British politics” with the “potential to bring about the end of liberal democracy as we know it”.

An open letter to Boris Johnson signed by more than 1,250 clergy from different Christian denominations across the UK says the “introduction of vaccine passports would constitute an unethical form of coercion and violation of the principle of informed consent”.

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What are the new Covid variants and what do they mean for the pandemic?

From Doug to Nelly and Eeek, we look at how mutations are affecting the battle against the virus

From the moment public health officials started to track new variants of coronavirus, it became clear that the same mutations were cropping up time and again and making the virus more troublesome. What are these mutations, what do they do, and what do they mean for the pandemic?

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Brazil warns women to delay pregnancy amid Covid-19 surge

Advice comes as country’s clinicians claim P1 Covid variant more aggressive during pregnancy

Brazil has warned women to delay getting pregnant until the worst of the pandemic passes, saying the virus variant that is devastating the South American country appears to affect expectant mothers more than earlier versions of the coronavirus.

The recommendation comes as Brazil continues to be one of the global epicenters of the pandemic, with more Brazilians dying of the virus each day than anywhere else in the world.

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Handwashing and hot tea: Eswatini celebrates roll out of solar-heated water

New stations at health clinics improve hygiene in locations where warm water seen as ‘an absolute luxury’, helping to tackle Covid

In Eswatini, the southern African country which lost a prime minister to Covid-19 in December and where most people have no access to hot water, handwashing – a key weapon in the fight against the pandemic – has been a problem.

No government health clinic in the kingdom, formerly known as Swaziland, had hot running water for patients. Nine out of 10 didn’t have hot water for operations and cleaning instruments.

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Malawi to bin 16,000 AstraZeneca doses amid fears of rise in vaccine hesitancy

Authorities act to counter rumours out-of-date shots are being used as people drag their heels over being vaccinated

More than 16,000 expired AstraZeneca Covid-19 doses are to be destroyed in Malawi as concerns over vaccine hesitancy increase.

The vaccines are among 102,000 doses donated by the African Union (AU) to the Malawian government last month.

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Rapid Covid testing in England may be scaled back over false positives

Exclusive: In leaked emails, Matt Hancock’s adviser says there is ‘urgent need for decisions’ on asymptomatic testing

Senior government officials have raised “urgent” concerns about the mass expansion of rapid coronavirus testing, estimating that as few as 2% to 10% of positive results may be accurate in places with low Covid rates, such as London.

Boris Johnson last week urged everyone in England to take two rapid-turnaround tests a week in the biggest expansion of the multibillion-pound testing programme to date.

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Covid-status certificate scheme could be unlawful discrimination, says EHRC

Exclusive: Equalities watchdog tells government documents could create ‘two-tier society’

Covid-status certificates being considered by ministers to help open up society could amount to unlawful indirect discrimination, the government’s independent equalities watchdog has advised.

As ministers decide whether the documents should be introduced as passports to certain events later this year, the Equality and Human Rights Commission has told the Cabinet Office they risk creating a “two-tier society”.

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Welcome to the new colonialism: rich countries sitting on surplus vaccines | Akin Olla

Last month, 130 countries had yet to administer a single dose of vaccine. Meanwhile the US has enough for three times its population

Old colonial lines are being reinforced. As western nations edge closer to effectively vaccinating their populations, much of the rest of the planet languishes in fear of new Covid variants and the long-term impacts of the pandemic and its economic consequences. The US has acquired enough vaccines for three times its population. At the same time, according to Unicef, 130 countries had yet to administer a single dose of vaccine as of mid-February. Some countries aren’t poised to see widespread vaccine access until 2023. While there are questions of unequal distribution within western countries like the US and UK, the larger problem is how the greed of governments – and the corporations that bully them – has caused a new and dangerous form of global inequality.

The US is, for lack of a better term, hoarding vaccines. It began with Donald Trump and his refusal to participate in Covax, a global initiative that aims to ensure the distribution of 2bn vaccines to countries in need. Joe Biden joined Covax but has for the most part deprioritized the organization for the sake of ensuring that Americans are vaccinated first and foremost – even if that means scores of vaccines go unused. After some criticism, Biden agreed to distribute some superfluous vaccines to Mexico and Canada. This is less an act of generosity than an act of self-interest, intended to ensure that the US vaccination process isn’t undone by having unvaccinated nations at its borders. In true American fashion, these vaccines are essentially loans.

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Hope, humour and zero-hours contracts: what four months as a vaccinator has taught me

After sitting alone in my flat for most of last year, I jumped at the chance to deliver Covid vaccines. This is what I’ve learned

Pushing a needle through fake skin is not much like the real thing. So I discovered when I vaccinated my first patient at a mass vaccination centre in north London. You feel for a person’s shoulder blade and give the injection two finger-widths below the tip of the shoulder, in the middle of the deltoid muscle. In training, you’re given a salmon-coloured “arm” of silicone sponge to practise on. In reality, arms – like the people they belong to – are unique; it takes a little while to confidently feel your way with each new person you close the NHS regulation blue curtain behind.

When I saw an advert for people willing to train as vaccinators in early January, I applied at once. The idea of being an active part of a historic vaccination rollout was thrilling. I have clinical experience as an assistant psychologist, can put people at ease and was very ready for a meaningful break from spending 10 hours a day looking at a screen alone in my flat. The training was delivered by a group of witty, absolutely zero-bullshit female clinicians wearing Crocs. The conversation was sharp; I adored them immediately. We covered infection control (including a sobering experiment with UV gel; trust me, you need to clean your thumbs), PPE, life support and, of course, learning to inject. I remember a surreal moment, looking around a room full of lawyers, medical students, psychotherapists, cycling instructors and shop managers in full PPE, all bound by the shared purpose of wanting to do something.

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Neglected tropical diseases are the landmines of global health | Albert Picado and John H Amuasi

They are 20 disparate diseases that, like mines, unduly affect the world’s poorest people. Now there’s a plan to eradicate them by 2030

In January the World Health Organization launched a new strategy for eradicating neglected tropical diseases, boldly setting targets to eliminate 20 of them by 2030.

But what are neglected tropical diseases (NTDs)? There is no easy answer. The concept was first proposed in the early 2000s to bring to light a group of diseases that disproportionately affect poor people yet, despite their collective impact, do not attract as much attention as diseases such as HIV/Aids, malaria or tuberculosis.

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Surge testing may not be enough to curb Covid variants in UK, say scientists

Local restrictions may be needed, specialists warn, as South Africa strain is identified in London

Local restrictions should be imposed to curb the spread of coronavirus variants when clusters emerge to avoid local or national lockdowns, scientists have said after the UK’s biggest surge testing operation got under way.

In south London, dozens of cases of the South Africa variant of Covid-19 have been detected, chiefly in the boroughs of Wandsworth and Lambeth, leading to what the Department of Health and Social Care (DHSC) has said is the “largest surge testing operation to date”.

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How UK doctor linked rare blood-clotting to AstraZeneca Covid jab

Prof Marie Scully developed a diagnostic test at University College London hospital after seeing rare side-effect in patient

Marie Scully was alarmed and puzzled. “It didn’t make sense,” she said. The consultant haematologist at University College London hospital (UCLH) had seen patients with blood clots in the brain and low platelets before and, although it was unusual, she always knew why. But there was no reason for the condition of the young woman in her 30s she was treating in early March.

“Now when you have blood clots in the brain like that there’s always a cause, and it was difficult to pinpoint the cause,” said Prof Scully. “It didn’t fit our normal diagnostic boxes, let’s say. She was a young woman with cerebral venous sinus thrombosis, and she had a low platelet count.”

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African health workers left without Covid jabs as paltry supplies dwindle

Fear of third wave and new variants as sub-Saharan vaccine distribution is dogged by supply disruption

Millions of healthcare workers in sub-Saharan Africa continue to risk their lives to fight Covid-19 as authorities across the continent struggle to obtain and distribute vaccines to frontline medical staff.

Though hundreds of millions of people in western nations are now protected from the virus, doctors, nurses and others on the frontline of the fight against Covid in Africa will have to wait months, or even years, for a vaccine.

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AstraZeneca blood clotting: what is this rare syndrome and how is it caused?

Evidence is growing of a link between the Covid-19 vaccine and a deadly thrombosis – and theories are emerging as to why

Since rare but severe clotting was seen in some people following vaccination with AstraZeneca’s Covid-19 vaccine, researchers worldwide have been grappling to understand why the clotting syndrome, known as “thrombosis with thrombocytopenia” (clotting with a low platelet count), occurs.

Most cases of these clots occurred in veins in the brain (a condition called cerebral venous sinus thrombosis, or CVST), though some occurred in other veins, including those to the abdomen (splanchnic vein thrombosis). It has a high death rate.

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Covid pandemic still growing exponentially, WHO says

World Health Organization says ‘confusion and complacency’ prolonging global situation

The global coronavirus pandemic is still growing exponentially, the World Health Organization said on Monday, as it reported 4.4m cases in the last week, the seventh straight week of rising numbers.

The latest global figures represent a 9% increase in infections on last week and a 5% rise in deaths.

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Covid-status certificates could lead to deliberate infections, scientists warn

Immunity certification could foster ‘an erroneous sense of no risk’ in people’s behaviour, according to analysts

Covid-status certificates – to allow those who have been vaccinated, recovered from the virus or have tested negative to attend an event or holiday abroad – could do harm as well as good, UK government science advisers have warned.

While they could encourage some people to get vaccinated, the scientists say others may deliberately go out to get infected, in order to test positive for antibodies and get a certificate enabling them to mix more freely.

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Is vaccinating against Covid enough? What we can learn from Chile and Israel

Contrasting lessons from the two countries, both with high rates of inoculation against the virus, show the danger is not past

A trio of countries stand out for the effectiveness of their Covid-19 vaccination programmes: Israel, Chile and the UK. All have managed to inoculate an impressively high percentage of their people but each has fared very differently in controlling the disease.

Israel has done so well it is resuming university lectures, concerts and other mass gatherings and has opened up its restaurants and bars. By contrast, Chile is experiencing soaring levels of Covid cases and faces new lockdown restrictions.

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