After nearly two years of debate about its possible benefits and risks, the gene editing technique is now here to stay. An article in the December 27, 2015 edition of the Sunday Observer told of the first recorded use of the inexpensive CASPR-Cas9 gene editing technology to cut and ‘splice out’ bad genes and replace them with healthy genes.
Category: Stem Cell Research
How zebrafish recover from blinding injuries
Researchers at Vanderbilt University in Nashville, Tennessee, have discovered that in zebrafish, decreased levels of the neurotransmitter gamma-aminobutyric acid cue the retina, the light-sensing tissue in the back of the eye, to produce stem cells. The finding sheds light on how the zebrafish regenerates its retina after injury and informs efforts to restore vision in people who are blind.
Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities.
To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document. Autophagy is a conserved pathway that delivers cytoplasmic contents to the lysosome for degradation.
Hart to Heart: The fight to save Nicholas’ life
The battle against B Cell High Risk Acute Lymphoblastic Leukemia has been beyond challenging for 12-year-old Nicholas Childers of Savannah. The Hancock Day School seventh-grader has endured multiple medical complications during rigorous treatment since being diagnosed with B-ALL in 2015.
The skinny on the benefits of brown fat
As a young man, Olivier Boss’s idea of a good time was to spend a summer day cycling a few hundred miles through the mountains of Switzerland or France. La Marmotte, he says, was an especially fun day: a 108-mile road race with nearly 17,000 feet of climbing.
Neuroscientists pinpoint key gene controlling tumor growth in brain cancers
A microscope image of brain cancer cells, a glioma tumor type known as anaplastic astrocytoma. Credit: Wikimedia/ CC BY-SA 3.0 Cedars-Sinai investigators have identified a stem cell-regulating gene that affects tumor growth in patients with brain cancer and can strongly influence survival rates of patients.
Canada continues to punch above its weight in the field of regenerative medicine
IMAGE: A new workshop report, Building on Canada’s Strengths in Regenerative Medicine, released today by the Council of Canadian Academies , confirms that Canadian researchers continue to be recognized as scientific… view more A new workshop report, Building on Canada’s Strengths in Regenerative Medicine, released today by the Council of Canadian Academies , confirms that Canadian researchers continue to be recognized as scientific leaders in the field of regenerative medicine and stem cell science. “Overall, the evidence shows that Canadian research in regenerative medicine continues to be strong,” said Dr. Janet Rossant, FRSC, Chair of the Workshop Steering Committee and President and Scientific Director of the Gairdner Foundation.
Unmet Demands Create Opportunity for Blockbuster Products for Treating Myelofibrosis
MarketResearchReports.biz has added a new market study to its repository, titled “Opportunity Analyzer: Myelofibrosis – Opportunity Analysis And Forecasts To 2025.” Myelofibrosis is a rare and serious blood disorder, which is characterized by bone marrow fibrosis.
Global Stem Cell Banking Market 2016: Manufacturers, Regions, Type and Application, Forecast
Latest industry research report on: Global Stem Cell Banking Market 2016: Industry Research, Size, Shares, Key Trends, Demand, Analysis, Performance, Growth, Segmentation, Parameters, Consumption and Prospects to 2021 Stem Cell Banking refers to the human stem cell transplantation for the purpose, with acquisition, processing, preservation and provides the ability to differentiate stem cell storage bank, has been called the “life bank”. Scope of the Report: This report focuses on the Stem Cell Banking in Global market, especially in North America, Europe and Asia-Pacific, Latin America, Middle East and Africa.
Stem cell treatment may restore vision to patients with damaged corneas
James Lauderdale is an associate professor of cellular biology in UGA’s Franklin College of Arts and Sciences . Researchers working as part of the University of Georgia’s Regenerative Bioscience Center have developed a new way to identify and sort stem cells that may one day allow clinicians to restore vision to people with damaged corneas using the patient’s own eye tissue.
New gene therapy allows French teen to dodge sickle cell disease
A French teen who was given gene therapy for sickle cell disease more than two years ago now has enough properly working red blood cells to dodge the effects of the disorder, researchers report. About 90,000 people in the U.S., mostly blacks, have sickle cell, the first disease for which a molecular cause was found.
Gene therapy lets a French teen dodge sickle cell disease
A French teen who was given gene therapy for sickle cell disease more than two years ago now has enough properly working red blood cells to dodge the effects of the disorder, researchers report. This 2009 colorized microscope image made available by the Sickle Cell Foundation of Georgia via the Centers for Disease Control and Prevention shows a sickle cell, left, and normal red blood cells of a patient with sickle cell anemia.
Gene therapy lets a French teen dodge sickle cell disease
A French teen who was given gene therapy for sickle cell disease more than two years ago now has enough properly working red blood cells to dodge the effects of the disorder, researchers report. About 90,000 people in the U.S., mostly blacks, have sickle cell, the first disease for which a molecular cause was found.
Monoclonal antibody drug superior to chemotherapy for advanced acute lymphoblastic leukemia
A Phase III clinical trial involving 101 centers in 21 countries revealed the monoclonal antibody blinatumomab to be more effective than standard chemotherapy for treatment of advanced acute lymphoblastic leukemia . Study findings were published in the March 1 online issue of the New England Journal of Medicine .
20 Years After Dolly the Sheep, Potential of Cloning Remains Unclear
On February 22, 1997, the world learned about a secret project that scientists at the Roslin Institute in Scotland had been working on. More than seven months earlier, on July 5, 1996, they had aided a Scottish Blackface sheep in giving birth to a Finn Dorset lamb codenamed 6LL3.
Caroline Wyatt: MS ‘brain fog’ lifted after stem cell treatment
BBC journalist Caroline Wyatt has spoken of how the “brain fog began to lift” after she had pioneering treatment for multiple sclerosis . The former BBC defence correspondent was deemed unsuitable for an NHS trial and paid $60,000 for a stem cell transplant in Mexico in January.
20 years after Dolly the sheep, potential of cloning remains unclear
JULY 05: Sophie Goggins from the National Museums Scotland views Dolly the Sheep during the opening of a major new development at the National Museum of Scotland on July 5, 2016 in Edinburgh,Scotland. On February 22, 1997, the world learned about a secret project that scientists at the Roslin Institute in Scotland had been working on.
20 years after Dolly
Everything you always wanted to know about the Dolly the cloned sheep and what came next, from a biomedical researcher and cloning expert. It’s been 20 years since scientists in Scotland told the world about Dolly the sheep , the first mammal successfully cloned from an adult body cell .
Strongsville man attemps stem cell treatment for MS Read Story Monica Robins
One Strongsville man is willing to take a chance, in the hopes he’ll get back some of what the disease has stolen from him. To look at him, Gary LaBuda appears to be the picture of health.
Study shows how old blood stem cells can be rejuvenated
When we are young, our blood stem cells produce an even and well-balanced number of red and white blood cells according to need. As we age, however, the capacity of the blood stem cells to produce the number of blood cells we need declines.
Study shows how old blood stem cells can be rejuvenated
When we are young, our blood stem cells produce an even and well-balanced number of red and white blood cells according to need. As we age, however, the capacity of the blood stem cells to produce the number of blood cells we need declines.
Nonalcoholicsteatohepatitis (NASH) Treatment Pipeline Review 2017
PUNE, INDIA, February 22, 2017 / EINPresswire.com / — Description: Non-alcoholic steatohepataitis Pipeline Analysis” gives comprehensive insights on the various drugs being developed for the treatment of NASH. The report covers all the drugs that are in various phases of development .
IQ4I Research released a new drug pipeline report on “Non-alcoholic…
This pipeline analysis gives comprehensive insights on drugs being developed for treatment of NASH & their various stages of development in 144 slide decks. BOSTON, MASSACHUSETTS, U.S., February 22, 2017 / EINPresswire.com / — ” Non-alcoholic steatohepataitis Pipeline Analysis ” gives comprehensive insights on the various drugs being developed for the treatment of NASH.
20 Years After Dolly the Sheep, What Have We Learned About Cloning?
Today marks the 20th anniversary of the announcement of Dolly the sheep , the first mammal cloned from an adult cell . Her creation left a lasting impact on both the public and the field of developmental biology, experts say.
Scientists use Deep Learning to predict development of hematopoietic stem cells
Autonomous driving, automatic speech recognition, and the game Go: Deep Learning is generating more and more public awareness. Scientists at the Helmholtz Zentrum MA1 4nchen and their partners at ETH Zurich and the Technical University of Munich have now used it to determine the development of hematopoietic stem cells in advance.
Stem cell transplants may help some with multiple sclerosis
Stem cell transplants may halt the progression of aggressive multiple sclerosis in nearly half of those with the debilitating disease, but picking the right patients for the treatment is key, a new study suggests. Specifically, younger patients with a relapsing form of MS who were not severely disabled and who hadn’t found relief with other treatments fared better than others over five years, the international team of researchers found.
Mayo doc’s stem cell experiment blasts into space
The SpaceX Falcon rocket launches from the Kennedy Space Center in Florida on Sunday. In addition to supplies for the International Space Station, the payload included a Mayo Clinic experiment involving stem cells.
Cell Expansion Market Is Worth USD 7.96 Billion in 2016 and Is…
According to the new market research report, ” Cell Expansion Market , by Products , Cells Types , Applications , End-users – Global Revenue, Trends, Growth, Share, Size and Forecast to 2022″, published by Scalar Market Research, the global cell expansion market is expected to reach USD 18.74 billion by 2022, growing at a CAGR of 15.30% from 2016 to 2022. According to the report, the market is expected to be worth USD 7.96 billion in the year 2016.
20 years after Dolly: Everything you always wanted to know about the cloned sheep and what came next
It’s been 20 years since scientists in Scotland told the world about Dolly the sheep, the first mammal successfully cloned from an adult body cell. What was special about Dolly is that her “parents” were actually a single cell originating from mammary tissue of an adult ewe.
Researchers create novel model that reveals cellular, molecular events driving leukemia progression
Mount Sinai researchers have created a novel model that shows the step-by-step progression from normal blood cells to leukemia and its precursor diseases, creating replicas of the stages of the disease to test the efficacy of therapeutic interventions at each stage, according to a study to be published in Cell Stem Cell. This research marked the first time scientists have been able to transplant leukemia from humans to a test tube and then into mice for study, a landmark feat that will allow for valuable research to help find therapies for blood cancer patients in the future.
Biological Safety Testing Market Is Expecting Worldwide Growth by…
Biologics are substance or products extracted or manufactured from biological sources such as living organisms, proteins, nucleic acid, or a complex combination of these substances. It includes a wide range of products such as gene therapy, somatic cells, tissues, recombinant therapeutic proteins, and blood components.
Scientists discover an unexpected influence on dividing stem cells’ fate
When most cells divide, they simply make more of themselves. But stem cells, which are responsible for repairing or making new tissue, have a choice: They can generate more stem cells or differentiate into skin cells, liver cells, or virtually any of the body’s specialized cell types.
Can banking baby teeth treat diabetes?
When she was just 11 months old, Billie Sue Wozniak’s daughter Juno was diagnosed with type 1 diabetes, an autoimmune disease that affects 1.25 million people and approximately 200,000 children under age 20 in the United States. The disease had affected several members of Billie Sue’s family, including her uncle, who passed away at the age of 30. “My first thought was, ‘Her life is going to be short,'” the 38-year-old from Reno, Nevada recalled.
Exhausting alloreactivity of donor-derived Car T cells
To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document. A study in mouse models of allogeneic stem cell transplantation with donor-derived CD19 chimeric antigen receptor T cells for the treatment of relapsed B cell malignancies indicates that T cell exhaustion might have a role in preventing allogeneic reactivity of CD19 CAR T cells.
Stem-cell-derived cells flag a possible new treatment for rare blood disorder
Researchers at Boston Children’s Hospital’s Stem Cell Research Program were able, for the first time, to use patients’ own cells to create cells similar to those in bone marrow, and then use them to identify potential treatments for a blood disorder. The work was published today by Science Translational Medicine .
New study uncovers important links between glioblastoma and epileptic seizures
Detecting brain tumors at the earliest possible stage and eliminating them before seizures begin might be possible one day, according to research by scientists at Baylor College of Medicine and Texas Children’s Hospital. In the study, which is published in the journal Nature Neuroscience , the scientists report that the emergence of specific brain cells during brain tumor progression in a mouse model marked the onset of seizures and brain tumor invasion.
Somatic cell transformation into stem cell-like cells induced by different microenvironments
Development of induced pluripotent stem cell technology introduced a novel way to derive pluripotent stem cells, but the genetic manipulation required to generate iPSCs may lead to uncontrolled tumorigenesis of the established cells and thus limit clinical feasibility of the technology. Numerous attempts have been made to date, and alternative reprogramming of somatic cells to reactivate cellular plasticity after differentiation has been suggested.
Search goes on for bone marrow match for Alastair
ANDREW and Judy Kim are still searching the globe for a donor for their two-year-old son after he was diagnosed with a rare genetic condition. Mr and Mrs Kim launched an appeal for help in September but the search is still on for a matching donor and their son still needs hospital treatment.
Induced pluripotent stem cell technology: a decade of progress
Nature Reviews Drug Discovery , Vol. 16, No. 2. , pp. 115-130, doi:10.1038/nrd.2016.245 To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document.
Induced pluripotent stem cell technology: a decade of progress
Nature Reviews Drug Discovery , Vol. 16, No. 2. , pp. 115-130, doi:10.1038/nrd.2016.245 To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document.