Malaria vaccine a step closer as experts urge Truss not to ‘turn off the tap’ on funding

Chance to eradicate diseases such as malaria could be lost and UK innovation squandered if global health investment is cut, jab co-creator tells PM

The co-inventor of a groundbreaking vaccine that could eradicate malaria has implored Liz Truss not to squander cutting-edge UK innovation by “turning off the taps” on global health funding.

Speaking as successful results from the latest trials of the R21 vaccine were revealed, Prof Adrian Hill, director of Oxford University’s Jenner Institute, said it would be tragic if Britain cut funding just as scientists were poised to make “a real impact” against malaria.

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Togo achieves ‘major feat’ of eradicating four neglected tropical diseases

WHO hails west African country as first in world to stamp out Guinea worm, lymphatic filariasis, sleeping sickness and trachoma

Togo has been praised by the World Health Organization for becoming the first country in the world to eliminate four neglected tropical diseases.

The WHO presented the west African country with an outstanding achievement award this week for eliminating Guinea worm, lymphatic filariasis, sleeping sickness and trachoma in just 11 years.

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India’s HIV patients say shortages leaving hundreds of thousands without drugs

Campaigners say many people have had to stop or switch antiretroviral medication regimes – but the government denies supply crisis

Hundreds of thousands of people living with HIV in India are struggling to access treatment because of a shortage of antiretroviral (ARV) drugs, according to campaigners.

Up to 500,000 people have not been able to get hold of free ARVs from government health centres and hospitals over the past five months, they say, as the country experiences stock shortages of key drugs.

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Leading figures urge drugs firm to lower price of ‘game-changing’ HIV prevention drug

Signatories including Olly Alexander, Stephen Fry and Joseph Stiglitz issue a letter asking ViiV to make cabotegravir affordable to low- and middle-income countries

Nobel laureates, business leaders, former premiers and celebrities have urged a UK pharmaceutical company to lower the price of its groundbreaking HIV prevention drug and ensure it is not kept “out of reach” of the world’s poor.

In a letter signed by dozens of high-profile figures, including Sir Richard Branson, the singer Olly Alexander, the economist Joseph Stiglitz and Helen Clark, the former prime minister of New Zealand, the pharmaceutical company ViiV Healthcare is praised for having developed the first of a new kind of HIV prevention drug.

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‘I saw an oncologist cry’: Tigray cancer patients sent home to die for lack of drugs

Doctors call for international help as Ethiopia civil war leaves terminally ill being treated with paracetamol in Mekelle hospital

Doctors caring for cancer patients at the main hospital in Tigray say they have only two chemotherapy drugs left in date and are treating terminally ill people with expired medication and paracetamol. Eighteen months of war have left the sickest in society suffering agonising deaths, they say.

For the first time in 11 months, doctors at the Ayder referral hospital in Mekelle took receipt of an oral chemotherapy drug earlier this month as part of an airlift by the International Committee of the Red Cross (ICRC). Until then, they had had only one, Doxorubicin, still in date.

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Médecins Sans Frontières suspends operations in parts of Cameroon over detained staff

Health charity in an ‘untenable position’ in anglophone parts of the country as it is accused of taking sides in internal strife

Medical charity Médecins Sans Frontières (MSF) has suspended its work in Cameroon’s south-west region and demanded the release of four staff members who have been detained for months, accused of helping secessionists.

Two MSF staff were detained at a checkpoint in December when they were transferring a patient with gunshot wounds. Another two were held by Cameroonian gendarmerie in January.

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UK Foreign Office rushed £4.2bn of aid cuts, official audit finds

Support slashed despite warnings about impact, with offices told not to discuss plans with local partners, says National Audit Office report

The British government forced through £4.2bn in aid cuts so quickly it had little time to plan the impact they would have, or consult partners, according to an official audit.

The National Audit Office (NAO) said bilateral spendingaid given directly to another governmentfaced some of the harshest cuts by the Foreign, Commonwealth and Development Office (FCDO) – 53% compared with less than a third of the overall aid budget – because of political and legal commitments to multilateral spending.

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‘Africa must be self-sufficient’: John Nkengasong on learning the deadly lessons of pandemics

The outgoing director of Africa Centres for Disease Control has seen Ebola, Aids and now Covid – and warns complacency is dangerous

The past five years have been “like going from one fire to the next, with barely any time to catch your breath”, says John Nkengasong, the outgoing head of the body charged with responding to health emergencies in Africa.

A relentless term as the first director of the Africa Centres for Disease Control and Prevention (Africa CDC) saw Nkengasong manage the response to Ebola and Lassa fever outbreaks. But nothing compared to the formidable test brought by Covid-19.

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Millions of children to be vaccinated for polio in Africa after Malawi detects case

First case of wild polio detected in Malawi for 30 years prompts emergency rollout of vaccinations in five African countries

More than 23 million young children across southern Africa will be offered vaccinations against wild polio after an outbreak of the virus was detected in Malawi for the first time since 1992.

Children under five in Lilongwe, Malawi’s capital, began to be immunised on Sunday as part of a mass drive against the disease.

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Global powers inch closer to agreement to waive Covid vaccine patents

The move would allow for cheaper generic versions to be manufactured and distributed among developing nations faster

Global powers have inched closer to an agreement to waive patents for Covid-19 vaccines, a move that would allow for cheaper generic versions to be manufactured and distributed among developing nations faster.

A leaked document, seen by the Guardian, reveals details of a compromise struck between the United States, the European Union, India and South Africa that would end a deadlock over an intellectual property waiver, 18 months after the proposal was first taken to the World Trade Organization.

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Harry and Meghan add voices to fierce critique of west’s Covid vaccine policies

Pair join Gordon Brown and 126 others in attack on ‘self-defeating nationalism, pharmaceutical monopolies and inequality’

Prince Harry and Meghan, the actor Charlize Theron and the former British prime minister Gordon Brown are among 130 signatories to a letter lambasting wealthy countries’ approach to the Covid-19 pandemic, labelling it “immoral, entirely self-defeating and also an ethical, economic and epidemiological failure”.

In a strongly worded open letter published on Friday, the signatories warned “the pandemic is not over”, and said the failure to vaccinate the world was down to “self-defeating nationalism, pharmaceutical monopolies and inequality”.

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Patients dying as conflict prevents supplies reaching Tigray hospitals

Medics unable to keep babies alive, says doctor, as Ethiopia’s civil war creates desperate shortages of drugs, oxygen, fuel and food

People in Tigray are dying due to a lack of oxygen and medicines, a doctor at the region’s largest hospital has said, as medics struggle to care for the sick amid frequent electricity blackouts and fuel shortages.

As the 16-month conflict between Tigrayan forces and Ethiopian government forces drags on, the isolated northern region of 5.5 million people continues to suffer under what the UN has called a de facto blockade.

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Increase funding or abandon hope of ending malaria, TB and Aids, UK warned

Global Fund urges UK and other donors to pledge billions to get efforts to end diseases by 2030 ‘back on track’ after catastrophic impact of Covid

Britain is being urged to pledge billions of dollars to get the fight against malaria, tuberculosis and Aids “back on track” after efforts were ravaged by the Covid-19 pandemic.

The UK has historically been one of the main donors to the Global Fund, an international financing organisation aimed at ending the three deadly epidemics by 2030. Now it is warning that, unless donors make an unprecedented total funding pledge of $18bn (£13.25bn) this year, that goal will be missed.

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Dr Paul Farmer, healthcare advocate for some of world’s poorest, dies aged 62

Farmer defied skeptics to create healthcare systems for the most vulnerable in places like Haiti, Rwanda and Peru.

Dr Paul Farmer, a physician, humanitarian and author renowned for providing healthcare to millions of impoverished people worldwide and who co-founded the global non-profit Partners in Health, has died. He was 62.

The Boston-based organization confirmed Farmer’s death on Monday, calling it “devastating” and noting he unexpectedly died in his sleep from an acute cardiac event while in Rwanda, where he had been teaching.

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My dying grandmother’s pain inspired me to challenge Zimbabwe’s pharmacy system | Dudzai Mureyi

Finding the right medicine at the right price was once a lottery – now the crowdsourcing service I set up is bringing down the cost of illness

In July 2015, as my 82-year-old grandmother, Sophie Mafuku, lay dying of a terminal illness in Zimbabwe, I spent a day speaking to fellow pharmacists as I tried to fill her morphine prescription. If it takes 24 hours for the grandmother of a well-connected medical professional to access scarce drugs, I thought, how long is it taking people with no connections? It set me off on a journey.

In Zimbabwe, systemic shortages are common. Sometimes, only a handful of pharmacies have particular drugs in stock. The shortages are caused by well-documented economic challenges, which affect Zimbabwe’s capacity to manufacture or import medicines.

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‘Babies here are born sick’: are Bolivia’s gold mines poisoning its indigenous people?

The government has been criticised for apparent inaction as evidence mounts that mercury contamination is causing illness in fishing communities

Outside a small brick house shared by four families, Daniela Prada, who is heavily pregnant, gathers guava leaves to make a tea for her two-year-old son.

“My baby gets sick a lot,” she says, boiling a pot of water in her outdoor kitchen. “He always has diarrhoea and last night he had a fever. Most of the time I give him natural medicine.”

In an identical house nearby, town leader Oscar Lurici says fevers are a part of life in Eyiyo Quibo village on the Beni River in northern Bolivia. People of all ages suffer from debilitating head and body aches, bouts of vomiting and diarrhoea, memory loss and tiredness. Some children show signs of cognitive development delays.

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Mandatory Covid jabs in Malawi ‘violate human rights’, say civil society groups

Measure aimed at frontline workers to reduce spread of Omicron variant may increase unrest in country with low vaccine take-up, critics warn

Civil rights groups in Malawi have cautioned the government on its decision to make the Covid-19 vaccination mandatory for frontline workers.

From January, it will be compulsory for public sector workers, including healthcare staff, police and teachers, as well as journalists, to be vaccinated, after an announcement by Malawi’s health minister, Khumbize Kandodo Chiponda, last week.

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Malaria kills 180,000 more people annually than previously thought, says WHO

UN agency says world must support urgent rollout of new vaccine as it reveals new figures for malaria deaths

The World Health Organization has called for a “massive, urgent” effort to get the new malaria vaccine into the arms of African children, as it warned that about 180,000 more people were dying annually from the disease than had previously been thought.

Dr Pedro Alonso, director of the WHO’s global malaria programme, said the RTS,S vaccine, recommended for widespread rollout in October, represented a historic opportunity to save tens of thousands of lives, mostly those of under-fives in sub-Saharan Africa.

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Activists call for revolution in ‘dated and colonial’ aid funding

Aspen Institute’s New Voices want donors to exercise humility and trust those receiving grants to know what their communities need

Aid donors are being urged to revolutionise the way money is spent to move away from colonial ideas and create meaningful change.

Ahead of a two-day conference this week, activists from Africa, Asia and Latin America have called on public and private global health donors – including governments, the United Nations, private philanthropists and international organisations – to prioritise funding for programmes driven by the needs of the community involved, rather than dictated by preconceived objectives.

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Warning on tackling HIV as WHO finds rise in resistance to antiretroviral drugs

Nearly half of newly diagnosed infants in 10 countries have drug-resistant HIV, study finds, underlining need for new alternatives

HIV drug resistance is on the rise, according to a new report, which found that the number of people with the virus being treated with antiretrovirals had risen to 27.5 million – an annual increase of 2 million.

Four out of five countries with high rates had seen success in suppressing the virus with antiretroviral treatments, according to the World Health Organization’s HIV drug-resistance report.

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