Two more UK mpox cases found in household contacts of first case

Total of three cases of Clade Ib strain now detected in UK but health security agency says risk to population still low

Two more UK cases of a strain of mpox that is thought to spread more easily have been detected in household contacts of the first case, the Health Security Agency (UKHSA) has said.

This brings the total number of confirmed cases of the Clade Ib mpox strain in the country to three.

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Pathogenic microbes blown vast distances by winds, scientists discover

Living microbes that cause disease in humans and host antibiotic-resistance genes carried 1,200 miles

Microbes that cause disease in humans can travel thousands of miles on high-level winds, scientists have revealed for the first time.

The winds studied carried a surprising diversity of bacteria and fungi, including known pathogens and, some with genes for resistance to multiple antibiotics. Some of the microbes were shown to be alive – in other words, they had survived the long journey and were able to replicate.

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African nations hit by mpox still waiting for vaccines – despite promises by the west

Last week’s planned rollout of doses faces further delays as campaigners complain of greed and inequality

None of the African countries affected by the outbreak of a new variant of mpox have received any of the promised vaccine, pushing back a rollout that had been planned for last week.

The Democratic Republic of the Congo (DRC) has been at the centre of an outbreak of the new clade 1b variant, with 18,000 suspected cases and 629 deaths this year, according to the World Health Organization (WHO).

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Africa to finally receive first batch of vaccines for deadly mpox virus

The continent will belatedly get 10,000 shots amid criticism of delays to the process caused by WHO red tape

Africa’s first batch of mpox vaccines will this week finally reach the continent, weeks after they have been made available in other parts of the world.

The 10,000 shots, donated by the US, will be used to tackle a dangerous new variant of the virus, formerly known as monkeypox, after a 2022 outbreak triggered global alarm.

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African health officials call for solidarity not travel bans over mpox outbreak

Head of Africa CDC Jean Kaseya urges international community to support rollout of testing and vaccinations

African health officials have appealed to the international community not to impose travel bans on countries dealing with an outbreak of mpox, but instead to support the continent in rolling out testing and vaccinations.

There have been about 1,400 new cases and 24 deaths linked to a new variant of mpox over the past week, according to the Africa Centres for Disease Control and Prevention.

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Mpox outbreak in Africa is public health emergency, declares WHO

Outbreak resembles early days of HIV, say experts, urging accelerated access to vaccines and testing

An outbreak in Africa of mpox, the disease formerly known as monkeypox, resembles the early days of HIV, scientists have said, as the World Health Organization declared it a public health emergency.

The declaration must accelerate access to testing, vaccines and therapeutic drugs in the affected areas, medical experts urged, and kickstart campaigns to reduce stigma surrounding the virus.

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Warnings over lethal and contagious strain of mpox as children in DRC die

Alarm over high mortality and miscarriage rates as mutated virus spreads in eastern Democratic Republic of the Congo

A dangerous strain of mpox that is killing children and causing miscarriages in the Democratic Republic of the Congo is the most transmissible yet and could spread internationally, scientists have warned.

The virus appears to be spreading from person to person via both sexual and non-sexual contact, in places ranging from brothels to schools.

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Huge number of deaths linked to superbugs can be avoided, say experts

Models suggest deaths in poorer countries could be cut by 18% – or about 750,000 a year – with preventive measures

Every year 750,000 deaths linked to drug-resistant superbugs could be prevented through better access to clean water and sanitation, infection control and childhood vaccinations, research suggests.

Antimicrobial resistance, or AMR, is a huge global challenge, with the evolution of drug-resistant superbugs, driven by factors including inappropriate and excessive antibiotic use, raising the prospect of a future where modern medicine fails.

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First scientist to publish Covid sequence in China protests over lab ‘eviction’

Zhang Yongzhen stages sit-in protest, as government attempts to avoid scrutiny over handling of outbreak

The first Chinese scientist to publish a genomic sequence of the Covid-19 virus, in defiance of government orders, has been staging a sit-in protest after claiming he was locked out of his laboratory.

Zhang Yongzhen, a virologist, said in an online post on Monday that he and his team had been given a sudden eviction notice from their lab, and guards had barred him from entering it over the weekend. The post, published on Weibo, was later deleted, Associated Press (AP) reported.

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‘Edible meadow’ for improved gut health to feature at Chelsea flower show

Flowers used in the ‘microbiome garden’ can enhance gut health by being eaten or just walked past

An “edible meadow” designed to improve gut health is to be displayed at the Chelsea flower show this year.

The two gardeners behind the “microbiome garden” say it will be filled with flowers that can enhance gut health by being eaten or just walked past.

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Patrick Vallance contradicts Rishi Sunak’s evidence to Covid inquiry

PM would almost certainly have known concerns over ‘eat out to help out’ scheme, says former chief scientific adviser

Rishi Sunak would almost certainly have known scientists were worried about his “eat out to help out” scheme during the pandemic, Sir Patrick Vallance has said, directly contradicting the prime minister’s evidence to the Covid inquiry.

In potentially damaging testimony, Vallance, the UK government’s chief scientific adviser during the pandemic, said he would be “very surprised” if Sunak had not learned about objections to his plan to help the hospitality industry.

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Australian gardener becomes first person to survive deadly flesh-eating bacteria

Woman treated with antibiotics and hyperbaric oxygen therapy to survive infection by pathogen that causes blackleg disease in cattle and sheep

An Australian woman has became the first documented person in the world to survive a pathogen that is usually the cause of the deadly “blackleg” disease in cattle and sheep.

The woman’s doctors this week published the case in the Medical Journal of Australia, detailing the successful treatment of the pathogen, after the only other two known cases in humans – one in the US and the other in Japan – had proved fatal.

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Nose-picking healthcare workers more likely to catch Covid, data suggests

Rhinotillexis may be underestimated cause of transmission between staff, say researchers

Nose-picking should be given greater consideration as a potential health hazard, researchers have said, after finding healthcare workers who engaged in rhinotillexis were more likely to catch Covid than those who refrained.

Scientists in the Netherlands say research has previously found healthcare workers who had direct contact with Covid patients were more likely to catch Covid than those who did not.

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Typhoid outbreak on refugee ship in Netherlands traced to raw sewage

Report finds that 72 cases of the disease on the vessel, which was housing asylum seekers, were caused by a wastewater leak

A major outbreak of typhoid among asylum seekers living on a ship in the Netherlands has been traced to raw sewage which was allowed to mix with tanks of freshwater for drinking and cooking.

A total of 72 cases of the highly contagious disease were confirmed during the spring 2022 outbreak on the Liberty Ann, an old cruise ship which was being used as emergency accommodation in Haarlem.

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Newly released Chinese Covid data points to infected animals in Wuhan

Previously unseen genomic samples suggest animals at Huanan market were potential source

Newly released data from early in the Covid-19 pandemic has offered a crucial insight into the outbreak’s origins, suggesting that Covid-infected animals were present at a market in Wuhan and could have been a “potential source of human infections”.

A pre-print report on Monday by a team of international researchers fleshed out analysis of previously unseen genomic samples collected by Chinese scientists at the Huanan market in Wuhan in the early days of the pandemic.

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Virus outbreak in West Bengal leaves 19 children dead and thousands in hospital

Indian state in crisis after adenovirus hits 12,000 people this year and families with sick children camp outside Kolkata hospital

Nineteen children have died of acute respiratory infections in West Bengal this year, and thousands more are in hospital as India grapples with an adenovirus outbreak.

More than 12,000 cases of adenovirus have been recorded in the state since January. More than 3,000 children have been admitted to hospital with severe flu-like symptoms.

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Plant toxin hailed as ‘new weapon’ in antibiotic war against bacteria

Scientists say albicidin has allowed them to take a giant step forward to creating a powerful new range of antibacterial drugs

Scientists have discovered a plant toxin whose unique method of dispatching bacteria could be used to create a powerful new range of antibiotics. The prospect of developing new antibacterial drugs this way has been hailed by doctors, who have been warning for many years that the steady rise of multidrug-resistant pathogens such as E coli now presents a dangerous threat to healthcare across the planet.

The new antibiotic – albicidin – attacks bacteria in a completely different way to existing drugs, a group of British, German and Polish scientists have revealed in a paper recently published in the journal Nature Catalysis. This suggests a new route could be exploited to tackle bacterial disease, they say.

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China rushes to boost intensive care beds, doctors and stocks of medicine as Covid surges

State media reports on increased efforts to boost health infrastructure, staffing and supplies

Chinese authorities are rushing to boost the number of intensive care beds and health workers and increase medication supplies as Covid-19 surges through the country.

Since the abrupt dismantling of the stringent zero-Covid regime, cases have skyrocketed in China. A full picture of the impact is difficult to gauge. Authorities have conceded it is “impossible” for the testing system to keep track, and the narrow parameters for attributing deaths to the virus mean the official count – fewer than 10 this week – is at odds with widespread anecdotal reports of fatalities and high traffic at funeral homes.

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Australia gives world-first approval for faecal transplants to restore gut health

BiomeBank in Adelaide collects healthy genetic material from the microbiomes of donors to treat potentially deadly bacterial condition

Australia has given regulatory approval for faecal transplants, the first country in the world to do so.

For such a transplant, poo donors – who have to meet a list of conditions – provide healthy genetic material from their microbiomes. The microbes are collected and delivered into the gastrointestinal tract of an unhealthy person, where they have been shown to treat conditions such as the potentially deadly bacteria Clostridium difficile colitis (C diff).

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Invasive mosquito could disrupt Africa’s ‘landscape of malaria’ after cases rise

Insecticide-resistant newcomer caused unprecedented urban outbreak in Ethiopia and can survive the dry season, scientists say

Scientists are warning that the invasion of an insecticide-resistant mosquito could change Africa’s “landscape of malaria” after research showed it caused an unprecedented urban outbreak in Ethiopia.

An investigation into a steep rise in cases in the Ethiopian city of Dire Dawa during a dry season this year identified the mosquito as the cause of the outbreak. Scientists say it is the strongest evidence to date that it could prompt surges of malaria in areas typically less affected by the disease.

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