Trump announces reforms to accelerate access to psychedelic drug treatments

President signed executive order directing FDA to expedite review of psychedelic drugs including ibogaine

Donald Trump on Saturday announced reforms intended to speed up access to medical research and treatment based on psychedelic drugs.

The president signed an executive order directing the federal Food and Drug Administration (FDA) to expedite review of drugs such as ibogaine, which US military veteran groups have said can help treat post-traumatic stress disorder.

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GSK reports promising early results in ovarian and womb cancer drug trial

Mo-Rez reduced or eliminated tumours in over 60% of patients and is expected to be a blockbuster drug

GSK has revealed positive results for a treatment for gynaecological cancers as its chief executive, Luke Miels, seeks to speed up drug development at the group.

The company said that in an early-stage trial Mocertatug Rezetecan, known as Mo-Rez, shrank or eliminated tumours in 62% of patients with ovarian cancer where chemotherapy had failed, and in 67% of those with endometrial cancer.

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Medicines watchdog to investigate UK peptide clinics over health claims

Exclusive: Guardian investigation finds several clinics making potentially unlawful claims about benefits of unregulated therapies

The medicines regulator is investigating whether UK clinics are breaking the law by making claims about the benefits of unregulated, experimental peptide therapies, the Guardian can reveal.

Interest in experimental peptides has boomed in recent years. The substances are delivered by injection and are touted by sellers, influencers and even some medics as aiding everything from anti-ageing to recovery from injury.

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What are peptides, are they safe and is there evidence to back up the hype?

Influencers and athletes are among those claiming substances can help with injury repair, weight loss and angi-ageing

From influencers to athletes, high-profile figures are hailing peptides as the route to wellness, claiming they help with injury repair, weight loss, anti-ageing and mood. We take a look at what these substances are, and the murky industry surrounding them.

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Nine charged over alleged conspiracy to import tonnes of cocaine and meth via ‘mother ship’ in Australian waters

Police allege drugs were to be collected from a drop zone in Bass Strait and distributed across the nation using trucking connections

When a commercial trawler sank off Victoria with four crew members needing rescuing, police became suspicious about an alleged drug trafficking operation.

Nine men are accused over a conspiracy to import tonnes of cocaine and methamphetamine before distributing the drugs across Australia using trucking connections.

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High times or low blows? Experts fail to clear air over German drug legalisation

Cannabis policy still divisive two years in, with SPD hailing it while CDU minister says it is risk to young people’s health

It was a landmark piece of legislation passed by Germany’s previous, centre-left-led government: a measure that legalised the personal recreational use of cannabis for over-18s despite warnings from critics it would cause a steep rise in the drug’s use, including by teenagers, and boost criminal gangs.

Two years on, controversy over the move has still not been stubbed out, with critics and proponents at odds over its impact on consumption, youth welfare and organised crime.

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Cannabis is not an effective treatment for common mental health conditions, says review

International researchers find ‘very little evidence’ medical form of the drug can treat anxiety, anorexia and other disorders

Cannabis is not an effective treatment for common mental health conditions despite the global surge in patients using it for that purpose, a review has found.

Researchers concluded there was “very little evidence for its efficacy” in treating anxiety, anorexia nervosa, psychotic disorders, post-traumatic stress disorder or opioid use disorder.

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Binge drinking rises sharply among gen Z in their early 20s

Research challenges idea of ‘generation sensible’ as alcohol and drug use increase after teenage years

Binge drinking rates among gen Z have risen sharply since their teenage years, according to research that challenges their reputation as “generation sensible”.

Almost seven in 10 (68%) 23-year-olds reported binge drinking in the past year, while nearly a third (29%) said they did so at least monthly, up from 10% at age 17.

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US military strike kills three in second alleged drug boat attack this week

Move brings total number of people killed in US strikes on suspected boats since September to at least 148

The US military launched a strike on an alleged drug smuggling boat in the eastern Pacific on Friday, killing three men in its second strike this week.

“Intelligence confirmed the vessel was transiting along known narco-trafficking routes in the Eastern Pacific and was engaged in narco-trafficking operations,” US Southern Command, which oversees operations in Latin America and the Caribbean, said on Twitter/X.

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Mexican authorities kill one of country’s top fentanyl traffickers

Pedro Inzunza Coronel, alias ‘El Pichón’, was killed during an anti-drug operation by the Mexican navy in Sinaloa

Mexican authorities have killed one of the country’s top fentanyl traffickers, accused of importing tens of thousands of kilos of the drug into the US and wanted by the US authorities on narco-terrorism charges.

Pedro Inzunza Coronel, alias “El Pichón”, (The Pigeon) was killed on Sunday during an anti-drug operation by the Mexican navy in the north-western state of Sinaloa.

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Princess of Wales calls for end to ‘stigma’ around addiction

Forward Trust patron says ‘compassion and love’ is needed to end fear and shame felt by those affected

The Princess of Wales has called for an end to the “stigma” surrounding addictions, saying the experiences of those dependent on drugs, alcohol or gambling are “shaped by fear, shame and judgment”.

Catherine, who is a patron of the charity Forward Trust supporting recovering addicts, said more open conversations were needed to bring the issue “out of the shadows” and for society to show “compassion and love” to those affected.

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US charges ex-Olympic snowboarder turned drug kingpin with murder of witness

Unsealed indictment says Ryan Wedding tracked down witness who was then murdered before he could testify

US authorities have charged a fugitive former Canadian Olympic snowboarder turned drug kingpin with the murder of a witness who was prepared to testify against him.

The attorney general, Pam Bondi, said on Wednesday that Ryan Wedding was accused in a newly unsealed indictment of tracking down a witness in Colombia who was then murdered before he could give evidence.

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Sheinbaum again dismisses Trump’s threat of sending troops to Mexico: ‘We do not want intervention’

Mexico’s president responds to Trump’s latest warning that he could authorize strikes against drug cartels in country

Mexico’s president, Claudia Sheinbaum, has again dismissed Donald Trump’s threat of military action against drug cartels inside her country, telling reporters: “It’s not going to happen.”

Sheinbaum made the comments on Tuesday morning in response to the US president’s latest warning that he could authorise strikes in Mexico.

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Drug dealer granted clemency by Trump sent back to prison for violating terms of release

Man accused of groping family’s nanny, evading bridge tolls and swinging IV pole at nurse and threatening to kill her

A convicted drug dealer who had been granted clemency by Donald Trump was sent back to federal prison on Monday for violating the terms of his release after being charged with several new crimes.

Jonathan Braun was sentenced to 27 months behind bars.

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Sheinbaum denies reports US will send troops to Mexico: ‘It’s not going to happen’

President says she’s repeatedly rejected such offers from Trump for US to confront Mexico’s powerful drug cartels

Mexico’s President Claudia Sheinbaum has flatly denied reports that the United States is planning to send troops into Mexico to confront the country’s powerful cartels, noting that she had repeatedly rejected such offers from Donald Trump.

“It’s not going to happen,” Sheinbaum said during her daily morning news conference on Tuesday. “We do not agree with any process of interference or interventionism.”

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UK must reform drug pricing to become life sciences superpower, says GSK boss

Shares jump on higher profits as Emma Walmsley is ‘hopeful’ standoff with NHS can be resolved

GSK’s outgoing chief executive, Emma Walmsley, has said Britain will struggle to be a “life sciences superpower” unless it overhauls drug pricing.

As ministers draw up proposals to increase the amount the NHS spends on new medicines by up to 25%, Walmsley said she was “hopeful and ambitious” that the standoff with the pharma industry could be resolved.

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Pentagon chief announces another US military strike on alleged drug boat in Caribbean

Pete Hegseth claimed that six ‘narco-terrorists’ onboard craft were killed in night strike in international waters

The US has carried out another military strike against what it claimed was a vessel carrying illegal drugs in the Caribbean, killing six people onboard, the Pentagon chief, Pete Hegseth, said.

In a social media post, Hegseth stated: “The vessel was known by our intelligence to be involved in illicit narcotics smuggling, was transiting along a known narco-trafficking route, and carrying narcotics.”

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Survivors reported after latest US attack on alleged drug boat in Caribbean

It is unknown whether US military rendered aid to survivors after attack on suspected ‘narcoterrorist’ vessel

The US military carried out a new strike on Thursday against a suspected drug vessel in the Caribbean, and in what is believed to be the first such case, there were survivors among the crew, a US official told Reuters.

The official, who spoke on condition of anonymity, did not offer additional details about the incident, which has not been previously reported. But it raises new questions, including whether the US military rendered aid to the survivors and whether they are now in US military custody.

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Highly potent synthetic opioids found in teddy bear-shaped pills linked to a death in Queensland

Public health warning issued after drugs known as nitazenes detected amid move to ban pill testing

Teddy bear-shaped pills laced with synthetic opioids have been linked to a death in Queensland, triggering a public health warning about a group of highly potent illicit drugs called nitazenes.

N-pyrrolidino-protonitazene and protonitazene were detected in toxicology and samples taken from pale yellow pills marked with the letter “Y” in the state’s south-east.

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Senate Republicans vote against check on Trump using deadly force against cartels

First vote in Congress on military campaign that White House says has hit four vessels and killed at least 21 people

Senate Republicans voted down legislation Wednesday that would have put a check on Donald Trump’s ability to use deadly military force against drug cartels after Democrats tried to counter the administration’s extraordinary assertion of presidential war powers to destroy vessels in the Caribbean.

The vote fell mostly along party lines, 48-51, with two Republicans, Rand Paul and Lisa Murkowski, voting in favor and the Democrat John Fetterman voting against.

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