Trump administration’s embattled FDA vaccine chief ousted for the second time

Vinay Prasad to leave in April after decisions involving vaccine reviews and specialty drugs for rare diseases

The top vaccine official at the Food and Drug Administration, Dr Vinay Prasad, is once again leaving the agency – the second time in less than a year that he’s departed after decisions involving the review of vaccinations and specialty drugs for rare diseases.

FDA commissioner Marty Makary announced the news to FDA staff in an email late Friday, saying Prasad would depart at the end of April. Makary said Prasad would return to his academic job at the University of California, San Francisco.

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Minneapolis killings and deportation outrage: Kristi Noem’s scandal-plagued DHS tenure

Backlash grew against homeland security secretary after slew of controversies from Trump’s immigration crackdown

Kristi Noem’s year-long tenure as homeland security secretary has been plagued by controversies as she led an aggressive immigration crackdown that hasprompted protests and lawsuits.

There have been scandals, legally dubious deportations condemned by human rights groups, taxpayer-funded publicity campaigns, and false claims about US citizens.

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Trump ousts DHS secretary Kristi Noem and replaces her with Republican senator

Noem’s tenure was marked by killings of US citizens by federal agents, a rumored affair and $220m spent on ads

Donald Trump on Thursday announced he was replacing Kristi Noem as the homeland security secretary, capping weeks of bipartisan complaints about her leadership after immigration agents killed two US citizens and reports emerged that she was involved in a personal relationship with a top deputy.

Noem’s firing was the first major personnel shake-up of Trump’s second term. The president made it public in a post on Truth Social, in which he said Markwayne Mullin, a Republican Oklahoma senator, would take over from Noem starting on 31 March – though Congress would need to vote to confirm the choice first. The secretary, who he said “has served us well, and has had numerous and spectacular results (especially on the Border!)”, would become special envoy for “the Shield of the Americas”, a security initiative Trump said he planned to announce over the weekend.

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RFK Jr urges medical schools to increase nutrition education training

As part of his Maha agenda, health secretary wants schools to incorporate 40 hours of instruction

Health secretary Robert F Kennedy Jr unveiled a new effort on Thursday aimed at increasing the amount of nutrition education taught in medical schools.

For months, Kennedy has urged medical schools to expand their nutrition curriculum and warned that institutions refusing to do so could face cuts to federal funding, while those that adopt the changes may receive public acknowledgment.

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Vanuatu moves forward with UN climate resolution despite Trump opposition

Pacific island says the US weakened its proposal to advance a key climate ruling but vows to hold major polluters accountable

The Trump administration’s attempt to sink a UN resolution demanding countries act on the climate crisis has caused cuts to the proposal but hasn’t entirely killed it, according to the tiny Pacific island country spearheading the effort.

The US has demanded that Vanuatu, an archipelago in the south Pacific, drop its UN draft resolution that calls on the world to implement a landmark international court of justice (ICJ) ruling from last year that countries could face paying reparations if they fail to stem the climate crisis.

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Pete Hegseth says US is ‘investigating’ deadly strike on girls’ school in Iran

US defense secretary was evasive when asked about the airstrike that Iranian officials say killed at least 165 students

Pete Hegseth, the US defense secretary, offered few details and was evasive when asked about the deadly strike on a girls’ school in Iran, saying only that the US was “investigating” the incident.

Iranian officials say the attack, which happened on Saturday, killed at least 165 students.

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Israel strikes Tehran and Beirut as Iran vows ‘complete destruction’ in region

Rapidly escalating war enters fifth day and spreads as far as Indian Ocean with sinking of Iranian vessel off Sri Lanka

Israel has carried out a wave of airstrikes on Iranian security targets and Hezbollah in Beirut as Tehran threatened the “complete destruction of the region’s military and economic infrastructure” as the rapidly escalating war entered its fifth day and reached as far as the Indian Ocean off Sri Lanka.

The Israeli military said it had hit buildings in Iran belonging to the Basij, the volunteer police arm of the Iranian Revolutionary Guards Corps (IRGC), and buildings belonging to internal security forces. Police stations and IRGC headquarters in the Kurdish regions of north-western Iran were also razed by strikes, Kurdish media reported.

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Cuba charges six exiles with terrorism in wake of deadly speedboat attack

Detainees accused of coming from the US with intent to sow chaos and attack military units on Communist-ruled island

Cuban prosecutors have formally charged six people with crimes of terrorism after a US-flagged speedboat was involved in a deadly shootout with Cuba’s coast guard last week.

The US-based Cuban defendants are accused of packing a boat with weapons and heading toward Cuba in hopes of destabilising the government in Havana.

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Democrats thrown into disarray as US offensive on Iran creates cracks

Lawmakers from Sanders to Mark Kelly offer mixed feelings on Trump’s action and killing of Iranian supreme leader

As Republicans celebrated the death of Iran’s supreme leader, Ayatollah Ali Khamenei, with praise for Donald Trump’s decisive action, Democrats faced their own divisions and a reckoning over how to present a united front.

Most were quick to condemn the US president for sidelining Congress to launch an illegal and unconstitutional war and demanded a swift vote on a war powers resolution that would restrain his military onslaught.

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Lack of a clear Iran plan could suck US into a long conflict: ‘Where does this go?’

Fears that decision to strike could be open-ended as Trump comes under pressure to spell out his vision for the country

Donald Trump is under pressure to spell out his vision for Iran amid the ongoing attacks on the country and reports of the first American casualties since the launch of unprovoked US and Israeli military strikes.

Trump’s critics are demanding that the White House provide greater clarity about what comes next. Opponents and analysts say the lack of a clear plan outlined so far has created a danger of the US being sucked into a long-lasting conflict of the sort that Trump repeatedly vowed to avoid.

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Starmer faces greater quandary over ‘special relationship’ after Iran attack

PM is in diplomatically precarious position of declining to endorse US strikes while also refusing to condemn them

It was perhaps naive of No 10 ever to position Keir Starmer as a “Donald Trump whisperer” capable of persuading the unpredictable US president to step back from reckless decisions.

The “special relationship” has been under severe strain in recent months over the UK’s decision to give up sovereignty of the Chagos Islands and the refusal of European countries to back Trump’s play for Greenland.

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Trump says Iran leadership agrees to talks after US and Israel strike Tehran

‘They should have done it sooner, they waited too long,’ says Trump but he doesn’t say when talks would take place

Donald Trump said on Sunday that Iran’s political leadership have agreed to talks, a day after the US and Israel began to target the country’s military and political infrastructure, killing the supreme leader Ayatollah Ali Khamenei and several top officials.

“They want to talk, and I have agreed to talk, so I will be talking to them,” Trump told a reporter for the Atlantic magazine on Sunday. “They should have done it sooner. They should have given what was very practical and easy to do sooner. They waited too long.”

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Protesters rally across US after strikes on Iran that killed Khamenei

Crowds gather in DC, New York and beyond to denounce Trump’s Iran strikes as an illegal act of war

As news circulated that Iran’s supreme leader, Ali Khamenei, had been killed in US and Israeli airstrikes on Tehran, anti-war protesters gathered across the United States, including outside the White House and in New York’s Times Square to voice opposition to US military involvement in the region.

“It wasn’t sanctioned by Congress, so what Trump is doing is on his own terms, it’s making him a fascist and it’s making the country into a fascist state,” said Sue Johnson, a protester.

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‘Viruses don’t know borders’: US anti-vaccine rhetoric could impact global measles crisis

Experts say global measles vaccination rates are falling as Trump officials signal a deprioritization of the virus

The US government has amplified anti-vaccine rhetoric and signaled that it does not consider measles to be a priority, which could have global ramifications as countries around the world have lost or are on the brink of losing measles elimination status.

The World Health Organization announced in late January that six European countries: the United Kingdom, Spain, Austria, Armenia, Azerbaijan and Uzbekistan had all officially lost their measles elimination status, which means the virus has been circulating continuously in those countries for more than 12 months. In order to contain measles, at least 95% of children should be fully vaccinated against it, according to health recommendations, but vaccination rates have been falling across Europe.

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Trump’s unprovoked attack on Iran has no mandate – or legal basis

US president violates UN charter just days into his Board of Peace era, and chooses to take the biggest gamble of his administration

The first war of Donald Trump’s Board of Peace era has begun – an unprovoked attempt at regime change in collaboration with Israel, with no legal foundation, launched in the midst of diplomatic efforts to avert conflict, and with minimal consultation with Congress or the American public.

Trump’s recorded eight-minute address after the first bombs had fallen, made clear that this would be no limited strike aimed at cajoling Tehran into concessions at the negotiating table. He warned that if Iran’s Islamic Revolutionary Guard Corps (IRGC) did not surrender they would be killed, and the country’s armed forces, its missile and navy would be smashed.

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US backs Pakistan’s ‘right to defend itself’ against Taliban after strikes on Afghanistan

Taliban offer to resolve dispute via dialogue after Pakistan bombed cities in Afghanistan in latest escalation with its neighbour

Washington endorsed Pakistan’s “right to defend itself” after it bombed major cities across Afghanistan amid heightened tensions between the two hostile neighbours.

The Taliban government in Kabul stressed it was ready to negotiate on Friday as violence intensified between the two countries.

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Renee Good’s family says Trump hasn’t contacted them after her death

Neither president nor anyone in administration has reached out after Good was killed by immigration officer, says family

The family of Renee Good, an unarmed US citizen and mother who was killed by a federal immigration officer in Minneapolis last month, said in an interview with NBC News that neither Donald Trump nor anyone in his administration has contacted them since her death.

“There’s a reason that we hired our own investigators – to make sure that the truth is transparent and available, to make sure that this is really taken seriously, and to make sure that we know what occurred,” Brent Ganger, Good’s brother, told NBC News.

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Trump advisers scramble to justify US military intervention in Iran

Tehran’s ICBMs cannot currently reach the US, experts say, and White House has claimed its nuclear programme has been destroyed

Donald Trump’s likely casus belli for an attack on Iran – which would be the largest US intervention since the Iraq war – is fraught with contradictions, and his top advisers have been left to cover for him as the White House makes the case for intervention.

In his State of the Union address this week, Trump alleged that Iran posed a direct threat to the US and that the country was “working to build missiles that will soon reach the United States of America”. But that claim has not been backed up with evidence by the White House or the Pentagon, and US intelligence reports from just last year say that it would take Iran 10 years to develop an intercontinental ballistic missile that could reach the US.

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Marco Rubio orders US officials to stop commentary that could strain Iran talks

Exclusive: memo came after Mike Huckabee’s remarks about Israel sparked alarm inside White House

The US secretary of state Marco Rubio told ambassadors in the Middle East to stop making public comments that could inflame tensions and undermine Donald Trump’s pressure on Iran to relinquish its capacity to produce a nuclear weapon, according to a memo obtained by the Guardian.

“Given rising tensions in the region, Chiefs of Mission and embassies at addressee posts must refrain from public statements, interviews, or social media activity that could in any way inflame regional audiences, prejudice sensitive political issues, or complicate US relationships,” the cable said.

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Democrats outraged at US military’s downing of CBP drone near Mexico border

Second time in two weeks military used laser to attack what it mistakenly thought was a threat, disrupting air traffic

Democratic members of Congress have expressed astonishment and anger at what they claim is the incompetence of the Trump administration after the US military used a laser on Thursday to shoot down what it thought was a threatening drone on the US-Mexico border in Texas but later turned out to belong to US Customs and Border Protection (CBP).

The apparent confusion between two entities in the US government led to airspace being closed around Fort Hancock, right along the border. It was the second time in two weeks that air traffic was disrupted in the region as a result of a high-energy laser being deployed against drones.

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