Cancer signs could be spotted years before symptoms, says new research institute

Tests that can identify early changes in cells would give doctors more time to offer treatment, say Cambridge researchers

Scientists at a recently opened cancer institute at Cambridge University have begun work that is pinpointing changes in cells many years before they develop into tumours. The research should help design radically new ways to treat cancer, they say.

The Early Cancer Institute – which has just received £11m from an anonymous donor – is focused on finding ways to tackle tumours before they produce symptoms. The research will exploit recent discoveries which have shown that many people develop precancerous conditions that lie in abeyance for long periods.

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Nearly 1,000 pharmacies in England closed since 2017, with poorer areas more affected

Exclusive: Millions more GP appointments potentially created as a result of closures

Almost 1,000 pharmacies in England have closed since 2017, potentially leading to millions of extra GP appointments, the Guardian can exclusively reveal.

There are more than 11,000 pharmacies in England. Guardian analysis of the official register of these chemists has found that parts of the country have lost more than one in five pharmacies in the last six years, with poorer areas experiencing proportionally more closures.

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Junior doctors in England vote to continue striking until mid-September

BMA members overwhelmingly back further stoppages and overtime bans in long-running pay dispute

Junior doctors in England have voted to keep on striking until the middle of September in their long-running pay dispute, bringing a fresh wave of disruption to the NHS.

Those belonging to the British Medical Association voted overwhelmingly to stage further stoppages in addition to the 41 days of strikes held since last March.

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Government urged to tackle poverty to help the NHS

Healthcare delays in deprived communities mean greater need for expensive emergency treatment, research finds

People living in poverty find it harder to live a healthy life and face barriers to accessing timely treatment, new research suggests.

A report by the King’s Fund, commissioned by the Joseph Rowntree Foundation, finds that the delays people living in deprived communities face for healthcare mean they are more likely to need expensive emergency treatment.

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Europe’s champion sitters: Even the sporty Dutch are falling victim to ‘chair-use disorder’

Long hours spent at desks and sofas leads to 21,000 deaths a year in the Netherlands from cardiovascular disease, diabetes and cancer

The Dutch are perceived as a nation of healthy giants, leaping on their bikes to cycle energetically across flat lands. But new research suggests they are in fact the “sitting champions of Europe”, with a sedentary lifestyle that causes thousands of early deaths.

Health experts are calling for urgent action to stop so-called “chair-use disorder” spreading across western countries. A report by the research organisation TNO, published on Friday, found too much sitting costs the Netherlands €1.2bn (£1bn) annually and leads to 21,000 premature deaths a year from cardiovascular disease, type 2 diabetes and cancer. It is riskier, researchers found, to be a lawyer than a lorry driver.

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‘Martha’s rule’ granting urgent second opinion to be adopted in 100 English hospitals

Initiative before national rollout will allow review of care for patients whose condition is deteriorating

Patients whose health is failing will be granted the right to obtain an urgent second opinion about their care, as “Martha’s rule” is initially adopted in 100 English hospitals from April at the start of a national rollout.

The initiative will allow patients and their loved ones to get a review of their condition and treatment directly from doctors and nurses not involved in the medical team treating them.

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More than 1.5m patients in England waited at least 12 hours in A&E in past year

Lib Dems say last month an average of 5,735 people a day faced waits of 12 hours or more to be seen

More than 1.5 million patients in England had to wait 12 hours or longer in A&E in the past year, according to figures that MPs say lay bare the impact of the government’s neglect of the NHS.

Last month 177,805 patients faced waits of 12 hours or more to be seen in emergency departments, an average of 5,735 a day. It means one in 10 patients (12.4%) arriving at A&E waited 12 hours before being admitted, transferred or discharged.

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Why does the UK lag behind on cancer care? – podcast

Britain’s cancer survival rates are improving but the UK still lags behind comparable countries. The Guardian’s health editor, Andrew Gregory, reports

The announcement last week that King Charles had been diagnosed with cancer has been met with sympathy and support for the 75-year-old. But alongside the focus on what it means for his future role as monarch, it has also led to a closer examination of what cancer care looks like in the UK in 2024.

For many, such as 37-year-old Nathaniel Dye, it has meant a diagnosis that has come too late. He has stage 4 bowel cancer, which has spread to other parts of his body. Dye has been told that in similar cases only 10% of people survive five years.

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Junior doctors in England to strike again after pay talks break down

BMA votes for further five days of action after meeting with health secretary fails to resolve grievances

Junior doctors are to stage fresh strike action in England for a 10th time after talks between their union and the government broke down again.

Ministers, health officials and representatives from the British Medical Association (BMA) had been locked in negotiations for weeks since last month’s record six-day stoppage, trying to find a resolution to the pay dispute.

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Primodos patients ‘betrayed’ after being left out of health scandals redress report

Families who may have been affected by hormone pregnancy tests not included in patient safety commissioner’s review

Campaigners have accused the UK government of betraying them after a review of redress for victims of health scandals excluded families who may have been affected by the hormone pregnancy test Primodos.

A report published on Wednesday by the patient safety commissioner, Dr Henrietta Hughes, found a “clear case for redress” for thousands of women and children who suffered “avoidable harm” from the epilepsy treatment sodium valproate and from vaginal mesh implants.

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NHS dentistry ‘recovery plan’ not worthy of the title, dentists say

British Dental Association says government’s plan does not offer hope to millions struggling to access care

Rishi Sunak has been accused of making a U-turn on his pledge to restore NHS dentistry as experts say his “recovery plan” does not offer enough money to incentivise dentists to take on extra NHS patients.

The prime minister’s long-awaited proposals have been criticised for failing to ringfence funding for the dental sector and reform the NHS dentistry contract, which means millions across the country will continue to struggle to access care.

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Rishi Sunak accused of personally holding up deal to end doctors’ strikes

Exclusive: Sources say PM has blocked talks due to concerns about knock-on effect of more generous pay offer

Rishi Sunak has been accused of personally holding up a deal to end doctors’ strikes in England despite warnings from the health department and NHS England that waiting lists will continue to soar unless the industrial dispute is resolved.

Sources told the Guardian it had been made “abundantly and repeatedly” clear to the prime minister that there would be no progress on his pledge to drive down NHS waiting lists until a deal was struck.

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New federal US rules to curb use of prior approval by private health insurances

Providers working in federal programs will be required to expedite patients’ prior authorizations for medications and/or surgery

A new set of rules from the Biden administration seeks to rein in private health insurance companies’ use of prior authorization – a byzantine practice that requires people to seek insurance company permission before obtaining medication or having a procedure.

The cost-containment strategy often delays care and forces patients, or their doctors, to navigate opaque and labyrinthine appeals.

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Disposable vapes to be banned in UK as part of drive to curb youth vaping

Plans to make vaping less appealing also to include restricting fruity flavours and introducing plain packaging

Ministers are to ban disposable vapes as part of a UK-wide drive to curb youth vaping.

The government is also seeking to make vaping less appealing to children by restricting sweet and fruity flavours, introducing plain packaging and making displays less visible in shops, under newly announced powers. The changes are expected to come into effect towards the end of this year or early 2025.

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EU plan for medicine stockpile could worsen UK’s record shortages

Bloc plans to bulk-buy key drugs for all 27 countries, potentially leaving Britain ‘behind in the queue’

The EU is to stockpile key medicines that will worsen the record drug shortages in the UK, with experts warning that the country could be left “behind in the queue”.

The EU is seeking to safeguard its supplies by switching to a system in which its 27 members work together to secure reliable supplies of 200 commonly used medications, such as antibiotics, painkillers and vaccines.

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Older people urged to get Covid jab as UK study shows avoidable deaths

More than 7,000 hospital admissions and deaths could have been avoided if people had been fully vaccinated

Older people are being urged to become fully vaccinated against Covid as a world-first study shows thousands of hospital admissions and deaths in the UK could have been avoided if everyone had had all of their doses.

The rollout began strongly in the UK, with 90% of the population over the age of 12 vaccinated with at least one dose by January 2022. However, rates of subsequent doses fell sharply, a study shows, with less than half the population fully jabbed by June 2022.

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Starmer to embrace ‘nanny state’ with plan for toothbrushing in schools

Labour leader hits out at perceived criticism as he attacks Tory record on child health

Keir Starmer has said he is “up for the fight” of defending the “nanny state” as he announced plans to improve child health under a Labour government, including supervised toothbrushing in schools.

The Labour leader said that children were “probably the biggest casualty” of the Tories’ sticking-plaster approach to politics over the past 14 years, adding that, if the government were a parent, they could be charged with neglect.

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Health inequalities ‘caused 1m early deaths in England in last decade’

Exclusive: Review by Michael Marmot decries 'shocking political failure’ behind differing life expectancies across country

More than 1 million people in England died prematurely in the decade after 2011 owing to a combination of poverty, austerity and Covid, according to “shocking” new research by one of the UK’s leading public health experts.

The figures are revealed in a study by the Institute of Health Equity at University College London led by Sir Michael Marmot. They demonstrate the extent to which stark economic and social inequalities are leading to poorer people dying early from cancer, heart problems and other diseases.

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Cancer and maternity patients at risk if junior doctors strike in January, NHS bosses warn

NHS Employers writes to British Medical Association warning of dangers of proposed six-day stoppage

Patients have been harmed as a result of doctors striking this year, and others needing time-critical treatment will be at risk during next month’s walkout in England, hospital bosses have said.

Cancer patients and women having induced or caesarean section births will be in danger of damage to their health unless junior doctors in those areas of care abandon their plans to strike for six days in January, they said.

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‘They all knew’: Michelle Mone hits out at Rishi Sunak over PPE deals

Former Tory peer says government was aware of her involvement in PPE Medpro ‘from the very beginning’

Michelle Mone has condemned Rishi Sunak after he expressed concern at her admission she lied about involvement in a company that won lucrative deals during Covid, saying the government “knew about my involvement from the very beginning”.

After the former Conservative peer admitted in a BBC interview on Sunday that she had been untruthful in denying a connection to PPE Medpro, which made millions of pounds in profits over a contract to provide personal protective equipment, Sunak said No 10 was taking the case “incredibly seriously”.

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