Head of US FDA’s advisory group: ‘We never expected Covid vaccines to be so good, so effective’

Dr Arnold Monto says he watched as a vaccine was developed both faster and more effectively than any dared to hope – but says it’s unlikely to give ‘permanent protection’

It is likely that in the “before times”, few Americans knew that independent experts advised the US Food and Drug Administration (FDA) on the safety and efficacy of vaccines, and that the FDA usually took their advice.

Less than a year into the Covid-19 pandemic, that quickly changed.

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Covid live news: 1.7 million people in UK had coronavirus last week; hundreds of Christmas flights cancelled

ONS figures are highest on record so far; Christmas for many in disarray as US and Australian airlines say flight crews hit by Covid

Here’s a story that echoes the cancellation of flights happening over the US.

Thousands of Australians have had their domestic flights cancelled in the hours leading up to Christmas, as frontline staff were ordered to test and isolate amid a rise in Covid cases.

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More options for Covid treatments in January as FDA approves two antiviral pills

The approval comes as reports of shortages in monoclonal antibody treatment arise and cases spike

People at greater risk of becoming seriously ill from Covid-19 will likely have more treatment options in January.

That’s the forecast in the wake of the US Food and Drug Administration’s approval this week of the first two antiviral pills used to treat Covid-19 and reports of shortages of a monoclonal antibody treatment used against the Omicron variant.

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Airport chaos as Christmas flights cancelled over Covid surge – as it happened

Labor MP Jim Chalmers was up and about on breakfast television earlier today, expressing shock at NSW premier Dominic Perrottet’s slow limp to reintroducing mask mandates.

He said mask mandates were just “common sense” right now:

It’s a bit strange frankly that they held out for so long and in that period we probably lost a bit of ground when it came to tracing and tracking outbreaks of the virus, particularly the new strain.

It’s an interesting thought but it’s not a thought which I think should turn into practice. We have a universal health system ... we care for people who need that care. We should encourage people to get vaccinated, it’s the best thing we can do to protect our health, but I don’t think our health system should discriminate.

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Anti-vaxxers serving ‘legal papers’ to Alan Shearer go to wrong address

Protest at property near Newcastle follows video of former England football captain urging people to get Covid booster

Anti-vaccination protesters who attempted to serve spurious legal papers to the former England football captain Alan Shearer delivered the documents to the wrong house, it has emerged.

The former Newcastle United and Blackburn Rovers striker had encouraged people to get a Covid booster jab in a video promoted by the Premier League last week.

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Australia Covid news live: Chant says roughly 80% of NSW cases are Omicron; WA to introduce mask mandate after community case

WA to introduce mask mandate after community case; SA records 484 new Covid cases; fires break out at Melbourne hotel housing refugees; NSW records 5,715 cases and one death; Victoria records 2,005 cases and 10 death; Queensland reports record 369 casess. Follow all the day’s news live

Covid-19 testing clinics are reducing their openings hours during the Christmas period despite “unprecedented demand” and reports of hours-long wait times in several states.

Guardian Australia analysis shows 77% of the 490 testing sites listed on the NSW Health website on Wednesday will either close or operate on reduced hours through the Christmas and new year period.

Novavax is still going through the approval process. I know they’re getting closer. We’re looking forward to get Novavax into the mix of available vaccines as well. It won’t be until the new year. I don’t know exactly when.

As soon as Novavax is ready to go, we’ll be delighted to get it out there. I know some people have been holding out for Novavax specifically. It will be part of our arsenal and we look forward to helping people access that vaccine if that’s what they want.

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Mandatory Covid jabs in Malawi ‘violate human rights’, say civil society groups

Measure aimed at frontline workers to reduce spread of Omicron variant may increase unrest in country with low vaccine take-up, critics warn

Civil rights groups in Malawi have cautioned the government on its decision to make the Covid-19 vaccination mandatory for frontline workers.

From January, it will be compulsory for public sector workers, including healthcare staff, police and teachers, as well as journalists, to be vaccinated, after an announcement by Malawi’s health minister, Khumbize Kandodo Chiponda, last week.

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WHO boss: western countries’ Covid booster drives likely to prolong pandemic

Dr Tedros Adhanom Ghebreyesus says there will be enough vaccines for world’s adults – if they are not hoarded

The world will have enough doses of Covid vaccines early next year to inoculate all of the global adult population – if western countries do not hoard those vaccines to use in blanket booster programmes, the head of the World Health Organization (WHO) has said.

Dr Tedros Adhanom Ghebreyesus said on Wednesday there would be sufficient vaccine supplies in global circulation in the first quarter of 2022.

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Israeli PM announces fourth Covid jab for over-60s to tackle Omicron

Booster will also be available to medical teams and immunodeficient people four months after third dose

Israel is set to become the first country in the world to offer a fourth dose of Covid-19 vaccines in an effort to protect against the Omicron variant.

People over the age of 60 and healthcare workers will be eligible for a second booster shot, the prime minister, Naftali Bennett, said on Tuesday night, following a recommendation made by Israel’s panel of pandemic experts.

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Data appears to support claims that Omicron is less severe in South Africa

Scientists warn, however, that lower severity of cases is not fully understood and may not occur elsewhere

South Africa has reported data on Covid cases driven by the Omicron variant that appears to give added impetus to claims the country is experiencing a lower severity of disease.

“In South Africa, this is the epidemiology: Omicron is behaving in a way that is less severe,” said Prof Cheryl Cohen of the country’s National Institute for Communicable Diseases (NICD), one of the authors of the study.

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Omicron is exploding – but scientists are better prepared than for any past variant | Manon Ragonnet-Cronin

We’re making progress in the arms race against the virus, but work in the lab must be supported by public health measures

It’s beginning to feel a lot like last Christmas. Case numbers of a new Covid variant are exploding across the UK, and the prime minister is cautioning that restrictions may be called for. But while the threat of Omicron likely surpasses that of previous variants, our tools to track and combat the virus have also advanced since last year.

The world was alerted to Omicron by the Botswanan and South African scientists who first sequenced the novel variant on 24 November, and it was designated as a variant of concern by the World Health Organization two days later. It was immediately obvious to them that they had something alarming on their hands when they saw the large number of mutations in the Omicron genome.

Dr Manon Ragonnet-Cronin is an MRC Fellow at Imperial College London and a member of the Imperial College Covid-19 response team

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Covid live news update: Australia Covid live news update: national cabinet to meet as testing centres overwhelmed; NSW records 3,763 new cases, Victoria 1,503 cases

PM says mask guidelines up to states; NSW records 3,763 new cases and two deaths; Victoria records 1,503 cases and six deaths; ACT records 58 cases; Tasmania records 12 cases; national cabinet to meet as confidence in interstate travel plummets. Follow all the day’s news

More than 300 doctors around the world have written to deputy prime minister Barnaby Joyce today urging him to seek Julian Assange’s immediate release from prison in the UK on medical grounds.

The letter cites concern over Assange’s apparent mini stroke, warning it may be “the tip of a medical iceberg”:

Indeed his symptoms suggest as much. It is therefore imperative that Mr Assange be released from prison, where his health will otherwise continue to deteriorate and where his complex medical needs cannot be met.

Perhaps our concerns were previously dismissed by your colleagues as hyperbolic. They are not. On the issue of cardiovascular pathology, we have been proven right. We do not wish to be proven right on the issue of Mr Assange’s survival.

We implore you, as Deputy Prime Minister, to intervene with the UK Government to seek Mr Assange’s immediate release on urgent medical grounds. We reiterate that he is an Australian citizen innocent in the eyes of the law, and guilty of and charged with nothing in the UK.

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Covid self-isolation cut to seven days with negative test in England

Public health bosses say move for those who test negative on days six and seven will help support essential services

The Covid self-isolation period has been cut to seven days in a move that could save Christmas for thousands of people and ease mounting staff shortages.

From Tuesday, new guidance will enable the 10-day self-isolation period for vaccinated people in England who have tested positive for coronavirus to be reduced by three days if they get the all-clear from lateral flow tests.

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Australia Covid live update: AMA calls for mask mandate and density limits for Christmas; NSW reports record 3,057 cases, Victoria 1,245

AMA calls for mask mandate and density limits for Christmas; South Australia records 154 new Covid cases, Queensland 86; RACP calls on state and territory governments to reintroduce restrictions as PM says ‘we’re not going back to lockdowns’; Victoria records 1,245 cases; NSW records 3,057 cases; national cabinet to discuss vaccination timeframes and mask mandates – follow all the day’s news live

According to Seven News Scott Morrison is supportive of an indoor mask mandate in light of the Omicron variant spreading throughout Australia, but not further lockdowns.

Thousands of customers are still without power on Sydney’s northern beaches after the brief but cyclonic weekend storm that felled power lines, leaving a trail of destruction, reports AAP.

It’s a very difficult time of year to be without power, and we apologise for the delays. We are doing everything we can to turn the lights back on as soon as possible. Where we can, we are progressively turning power back on, and as always the safety of our customers and staff remains our number one priority.

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Global Covid vaccination failure will harm Britain, Gordon Brown warns

Exclusive: Ex-PM says virus will have ‘free rein to mutate’ unless richer countries fund $23bn vaccine drive

The failure to vaccinate the world against coronavirus will come back to haunt even fully vaccinated Britons in 2022, Gordon Brown has warned.

The former prime minister said the emergence of Omicron was “not Africa’s fault”, and added that new variants would continue to wreak havoc because richer countries such as the UK had “stockpiled” hundreds of millions of vaccines.

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Covid live: Thailand to consider ending quarantine-free travel; EU set to back Novavax vaccine

Bangkok considering reinstating mandatory quarantine due to spread of Omicron; EU’s drug regulator will decide on whether to approve Novavax

Thailand’s public health minister said on Monday that his ministry will propose reinstating mandatory quarantine for foreign visitors due to concerns over the spread of the Omicron variant.

The proposal would scrap the current quarantine waiver for vaccinated visitors and revert to hotel quarantine and the “sandbox” programme, which allows free movement within a specific location, Anutin Charnvirakul told the Inside Thailand television show.

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Moderna says booster produces strong antibody response to Omicron

Pharmaceuticals firm says third dose of its Covid vaccine increases antibodies against variant by 37-fold

The pharmaceuticals company Moderna has said a booster dose of its Covid vaccine appeared to protect against the fast-spreading Omicron variant in laboratory testing and that the current version will continue to beits “first line of defence against Omicron”.

The decision to focus on the current vaccine, mRNA-1273, was driven in part by how quickly the variant is spreading. The company plans to develop a vaccine specifically to protect against Omicron, which it hopes to advance into clinical trials early next year.

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Fauci: Omicron ‘raging through the world’ and travel increases Covid risks

The Omicron variant of Covid-19 has “extraordinary spreading capabilities”, the top US infectious diseases expert said on Sunday, and promises to bring a bleak winter as it continues “raging through the world”.

Dr Anthony Fauci’s warning came ahead of the busy holiday travel period, which he said would elevate the risk of infection even in vaccinated people.

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Kamala Harris concedes White House ‘didn’t see’ Delta and Omicron coming

Vice-president’s candid admission on Covid variants came in wide-ranging interview with the Los Angeles Times

Kamala Harris has conceded that the Biden administration was blind to the emergence of the Delta and Omicron variants of Covid-19, and said she fears “misinformation” over vaccines will prolong the pandemic well into a third year.

The candid admission came in a wide-ranging interview with the Los Angeles Times, which followed reports that the vice-president was “struggling” to make a mark as Joe Biden’s No 2 and was keen for a more prominent role.

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Guests urged to be vaccinated at anti-vaxxer Robert F Kennedy Jr’s party

Kennedy said his wife, Cheryl Hines, was behind it and that he is ‘not always the boss at my own house’

Guests invited to a holiday party at the home of the leading anti-vaxxer Robert F Kennedy Jr were urged to be vaccinated or tested for Covid-19 because, Kennedy said, he is “not always the boss at my own house”.

Speaking to Politico, which reported the request before the party in California last week, Kennedy said his wife, the actor Cheryl Hines, was behind it.

The Associated Press contributed to this report

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