‘A tsunami of cases’: desperation as Covid second wave batters India

Doctors speak of a new variant of the virus that appears to be spreading faster than ever before

Dr K Senthil had feared it was coming.

He had feared it as he saw the reckless crush of hundreds of people taking part in large wedding parties over the past months, feared it as he saw the maskless faces of shoppers at the market, feared it as he witnessed thousands come together for political rallies in the ongoing elections in the Indian state of Tamil Nadu, where he is the president of the state medical council.

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Coronavirus live news: Johnson & Johnson to ‘proactively delay’ vaccine rollout in Europe over blood clot reports

Move to delay vaccine deployment in Europe comes after six blood clot cases detected among Johnson & Johnson jab recipients in US

South Africa has temporarily suspended the rollout of Johnson & Johnson’s Covid-19 vaccine, its health minister said on Tuesday, after US federal health agencies recommended pausing its use because of rare cases of blood clots.

Health minister Zweli Mkhize told reporters:

I had urgent consultations with our scientists, who advised that we cannot take the decision by the FDA lightly. Based on their advice, we have determined to voluntarily suspend our rollout until the causal relationship between the development of clots and the Johnson & Johnson vaccine is sufficiently interrogated.

The European Medicines Agency (EMA) said on Tuesday it was reviewing cases of rare blood clots in women who had taken Johnson & Johnson’s Covid-19 vaccine after US federal health authorities recommended pausing the use of the shot.

In a statement to Reuters, the EMA said it was “currently not clear whether there is a causal association between vaccination” and the conditions.

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US decision to pause J&J jabs is another blow to global Covid fight

Analysis: rare side-effects mean that confidence in both the Johnson & Johnson and Oxford/AstraZeneca vaccines is now shaken

The call in the US for a pause in the use of the single-shot Johnson & Johnson Covid vaccine is another blow to hopes of vaccinating the whole world as fast as possible.

Health agencies recommended that US states pause use of the jab while investigations take place into six cases of women who have experienced rare blood clotting events combined with low platelets in the days following vaccination.

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How UK doctor linked rare blood-clotting to AstraZeneca Covid jab

Prof Marie Scully developed a diagnostic test at University College London hospital after seeing rare side-effect in patient

Marie Scully was alarmed and puzzled. “It didn’t make sense,” she said. The consultant haematologist at University College London hospital (UCLH) had seen patients with blood clots in the brain and low platelets before and, although it was unusual, she always knew why. But there was no reason for the condition of the young woman in her 30s she was treating in early March.

“Now when you have blood clots in the brain like that there’s always a cause, and it was difficult to pinpoint the cause,” said Prof Scully. “It didn’t fit our normal diagnostic boxes, let’s say. She was a young woman with cerebral venous sinus thrombosis, and she had a low platelet count.”

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African health workers left without Covid jabs as paltry supplies dwindle

Fear of third wave and new variants as sub-Saharan vaccine distribution is dogged by supply disruption

Millions of healthcare workers in sub-Saharan Africa continue to risk their lives to fight Covid-19 as authorities across the continent struggle to obtain and distribute vaccines to frontline medical staff.

Though hundreds of millions of people in western nations are now protected from the virus, doctors, nurses and others on the frontline of the fight against Covid in Africa will have to wait months, or even years, for a vaccine.

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Australia news live: Christine Holgate says she was ‘bullied’ and Australia Post chairman fabricated evidence

Holgate says she was ‘humiliated’ by prime minister Scott Morrison; man dies of coronavirus in Queensland. Follow all the latest news and updates, live
• Australia won’t purchase Johnson & Johnson jab
AstraZeneca blood clotting: what is this rare syndrome?
• Andrew Laming blocked from recontesting next election
More than half of Australians think vaccine rollout is too slow

Wow, it’s been a busy few hours! With that, I’m going to hand you over to Michael McGowan to take you through the rest of the afternoon.

Christine Holgate gave some evidence about executive bonuses. It is a little confusing and we’ll come back to it, because even the senators seem a little confused about what is being said. And it’s important we get it right, so I’ll head back over the transcript to see what she was saying there.

Liberal senator Sarah Henderson has the question call now. She says she has been very moved by Holgate, and what she went through. She asks whether she thinks the questioning on the 22 October estimates hearing was fair.

Holgate:

In all honesty, I didn’t consider whether it was fair or not fair. I absolutely respect and Senator Carr, forgive me but you’ve asked me many tough questions over my time with you (“that’s my job,” Carr says)...and I was about to say ‘that’s your job’.

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All over-50s and high-risk groups in UK offered vaccine ahead of target date

Achievement hailed by PM as ‘hugely significant milestone’ means people in late 40s should be next to be immunised

All over-50s and high-risk groups in the UK have been offered a coronavirus vaccine a few days before the mid-April deadline set by the government – meaning the second phase of the rollout to younger cohorts can now begin.

Despite fears of a supply slowdown and possible knock in confidence after a change in advice on who could get the Oxford/AstraZeneca jab, Boris Johnson hailed the passing of “another hugely significant milestone”.

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Covid vaccine passports: what can we learn from Israel? – video explainer

Israel became the first country in the world to test vaccine passports when it announced the 'green pass' scheme in February. The passes allow people who have had two doses of a Covid-19 vaccine to return to restaurants, theatres and sport events.  With many countries planning to reopen after their vaccination campaigns, the Guardian's Jerusalem correspondent, Oliver Holmes, examines the lessons that could be learned from Israel's rollout

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Gordon Brown calls for G7 to act on Covid vaccine ‘apartheid’

Former prime minister says group should commit to global vaccine drive and slams UK’s foreign aid cut

Preventing poor countries suffering from vaccine “apartheid” will require the G7 group of rich nations to commit $30bn (£22bn) a year to a global immunisation drive, Gordon Brown has said.

The former Labour prime minister said the UK should use June’s G7 summit in Cornwall to rekindle the moral purpose of the Make Poverty History campaign of 2005, paying for its share of the new fund by reversing the government’s “misguided” cut to the foreign aid budget.

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Is vaccinating against Covid enough? What we can learn from Chile and Israel

Contrasting lessons from the two countries, both with high rates of inoculation against the virus, show the danger is not past

A trio of countries stand out for the effectiveness of their Covid-19 vaccination programmes: Israel, Chile and the UK. All have managed to inoculate an impressively high percentage of their people but each has fared very differently in controlling the disease.

Israel has done so well it is resuming university lectures, concerts and other mass gatherings and has opened up its restaurants and bars. By contrast, Chile is experiencing soaring levels of Covid cases and faces new lockdown restrictions.

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Australia’s Covid vaccination relying on opaque private contracts worth millions

Lack of transparency over deals with private consultants, logistics companies and healthcare contractors adding to ‘layers of confusion’ over rollout

The Australian government is funnelling millions of dollars to private contractors for its beleaguered Covid vaccine rollout using opaque deals – some of which are hidden from the public and ignore transparency standards.

The government is relying heavily on contractors to aid its vaccine rollout, including multinational consultants PwC and Accenture, logistics companies DHL and Linfox, and healthcare contractors Healthcare Australia, International SOS, Sonic Clinical Services and Aspen.

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France and Germany’s Covid vaccination programmes pick up speed

As daily inoculations hit record figures, warning comes of new delays

Vaccine rollouts in France and Germany have finally begun to pick up speed, after a slow start and problems with supplies and bureaucracy.

France continues to struggle to contain a third Covid-19 wave, but announced it had hit its 10 million inoculations target a week earlier than expected, while Germany doubled the number of vaccinations, administering a record 720,000 doses on Thursday after the rollout was extended to family doctors.

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EU agency examines reports of blood clots with J&J Covid vaccine

EMA says four serious cases reported, one fatal, and also expands inquiry into AstraZeneca vaccine

The EU’s drug regulator is reviewing reports of rare blood clots in four people who received Johnson & Johnson’s Covid-19 vaccine and has expanded its inquiry into AstraZeneca’s shot to include reports of a bleeding condition.

Of the four serious cases of clotting and low platelets, three occurred in the US during the rollout of J&J’s vaccine from its Janssen pharmaceuticals unit, the European Medicines Agency (EMA) said on Friday, adding that one person had died and one case was reported in a clinical trial. It was the first news of EMA’s inquiry into the J&J vaccine.

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Merkel sets out plan to take control of Germany’s Covid response

Bill would give national government power to impose restrictions in states with high infection rates

The German chancellor, Angela Merkel, plans to take control over the Covid-19 response from federal states to impose restrictions on regions with high numbers of new infections, as the head of the country’s disease control agency said Germany needed a two- to four-week lockdown to prevent hospitals from being overwhelmed.

“Germany is in the middle of a third wave, so the federal government and the states have agreed to add to the national legislation,” a spokesperson for the German chancellor told reporters on Friday.

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Coronavirus Australia live update: Scott Morrison announces 20m more Pfizer vaccine doses after problems with AstraZeneca-led rollout

Vaccine rollout faces delays as authorities scramble to secure alternatives to AstraZeneca such as Pfizer for under-50s over blood clot fears. Follow updates live

Labor MP Josh Burns has criticised the government for failing to deliver vaccines to aged care staff and residents, noting the issue is unrelated to fresh concerns about the AstraZeneca vaccine causing blood clotting in those under 50.

Burns’ comments follow reports in the Guardian this morning that the federal government is expected to miss a self-imposed target on delivering “pop-up” hubs to vaccinate critical aged care staff and has given no details on the proposal to workers, despite multiple requests for information and meetings from the nursing union.

We’ve not had any federal aged care providers in Macnamara receive their vaccinations or have any indication on what day they are going to be having them, not to mention the staff that are still vulnerable and haven’t been vaccinated.

The frustration that Australians rightly have is that the promises that have been made have not been made by the Labor Party, they’ve been made by Greg Hunt, they’ve been made by Scott Morrison, they’ve been telling Australians that they’ve got it under control, that all is well, they are going to be vaccinating Australians and they haven’t been.

Related: Australia’s aged care nurses still in the dark about promised ‘pop-up’ vaccination hubs

Women need more information about contraceptive options, experts said, after concerns over rare blood clots linked to the AstraZeneca Covid jab prompted a debate over side-effects caused by certain forms of the pill.

On Wednesday the UK’s Medicines and Healthcare products Regulatory Agency (MHRA) said that evidence that the jab could be causing a rare blood clotting syndrome was growing stronger. As a result the UK’s Joint Committee on Vaccination and Immunisation (JCVI) recommended that healthy people under the age of 30 who were at low risk of Covid should be offered a different vaccine if possible.

Related: Contraception blood-clot risk: ‘public need better access to advice’

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Tens of thousands of Australians left in the lurch as AstraZeneca Covid vaccine advice changes

Doctors say their phones have been ‘running hot’ and some states bar anyone under 50 getting the AstraZeneca jab

States and territories have been left scrambling to respond to government advice recommending against vaccinating anyone under 50 with the AstraZeneca Covid-19 vaccine, leaving tens of thousands of people in the lurch.

On Friday, New South Wales halted its AstraZeneca rollout entirely for several hours while patient consent forms with the latest information about the rare risk of severe clotting associated with the vaccine were added. The state’s rollout for people aged 50 and over has since resumed.

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UK recognition of EU’s vaccine effort would not go amiss, says Brussels

Europe could have fully vaccinated 70% of adults before UK reaches its target, says head of EU taskforce

The UK will be reliant on the EU to complete its vaccine rollout and a little recognition of that would not go amiss, the European commissioner leading Brussels’ vaccine taskforce has said – adding that Europe could have fully vaccinated 70% of adults before the UK reaches its own target of one dose for all over-18s by the end of July.

Thierry Breton also said AstraZeneca had agreed that almost all the Covid vaccine doses made in the Netherlands over which the UK has made a claim will stay in the EU.

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Germany seeks Russia talks over possible supply of Sputnik V

Germany could act independently of EU but would require regulator’s approval of Covid vaccine

Germany’s health minister has said he wants to hold talks with Moscow about obtaining supplies of the Russian vaccine Sputnik V, in an effort to boost the country’s inoculation campaign.

Jens Spahn said Germany would have no hesitation in acting independently of the European Union, indicating his frustration over the bloc’s refusal to engage with the Russian jab’s manufacturers, but he stressed that the vaccine would only be used if it was approved by the European Medicines Agency (EMA).

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UK ministers silent on AstraZeneca vaccine shipment to Australia

Downing Street will not confirm or deny report that more than 700,000 Covid jabs were sent after EU blocked export

British ministers and officials did not deny that more than 700,000 shots of the AstraZeneca vaccine were secretly dispatched from the UK to Australia a few weeks ago as the EU blocked the drug’s export.

The Sydney Morning Herald reported that 717,000 AstraZeneca doses were dispatched in late February and March from the company’s British operations – also during a period when the EU was demanding the vaccine from the UK.

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Brazilian Covid variant: what do we know about P1?

What threat does variant that is causing devastation in Brazil pose, and how is it different?

The P1 variant is causing devastation in Brazil, where an uncontrolled Covid pandemic is raging. P1, behind the terrible scenes of hospital overload in Manaus with patients’ relatives pleading for oxygen cylinders, is now the dominant form of coronavirus in many of Brazil’s cities and partly responsible for the high death toll. Other Latin American countries have closed their borders and restricted travel to and from Brazil but P1 is now in at least 15 countries in the Americas, according to the Pan American Health Organization (PAHO).

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