Weight-loss drugs may prevent thousands of knee replacements, study suggests

Patients with knee arthritis who took medications for at least three years at reduced risk of needing surgery

Taking weight-loss drugs for at least three years could prevent thousands of knee replacements a year, research suggests.

Globally, more than 500 million people have osteoarthritis. Knee arthritis is the most common form, affecting about 14 million people in the US and more than 5 million in the UK. Many will require knee surgery. In the UK more than 120,000 knee replacements are carried out every year.

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Knee surgery for cartilage damage does not benefit patients, study suggests

People with meniscus tears who underwent surgery had poorer knee function and worse osteoarthritis after 10 years than those who did not

A common knee surgery for cartilage damage does not benefit patients and may lead to worse outcomes, a 10-year trial suggests.

The study tracked outcomes for patients treated for a meniscus tear, who were given a partial meniscectomy, one of the most common orthopaedic surgeries. Their trajectories were compared with patients who had randomly been assigned to receive “sham surgery”, in which no procedure was carried out.

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Autoimmune disease may almost double risk of mental ill health, study suggests

Chronic exposure to inflammation may explain link to conditions including depression, anxiety and bipolar disorder, researchers say

Living with an autoimmune disease may almost double the risk of mental health conditions including depression, anxiety and bipolar disorder, a study suggests.

The link may be explained by the chronic exposure to systemic inflammation that the autoimmune disease causes, researchers at the University of Edinburgh said.

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Children living near green spaces ‘have stronger bones’

Bone strength is set in childhood so better park access could prevent fractures in older people, study finds

Children with more green space near their homes have significantly stronger bones, a study has found, potentially leading to lifelong health benefits.

Scientists found that the children living in places with 20-25% more natural areas had increased bone strength that was equivalent to half a year’s natural growth.

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Our ‘inner salamander’ could help treat arthritis, study finds

Research links human ability to regrow cartilage to molecules that help amphibians sprout new limbs

Contrary to popular opinion, humans can regrow cartilage in their joints, researchers have found. Experts hope the research could lead to new treatments for a common type of arthritis.

Osteoarthritis, in which joints become painful and stiff, is the most common form of arthritis and is thought to cause pain in about 8.5 million people in the UK alone. It is caused by a breakdown in the cartilage that protects the ends of the bones, as well as the growth of new bone around the joint as the body tries to repair the damage.

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