US decision to pause J&J jabs is another blow to global Covid fight

Analysis: rare side-effects mean that confidence in both the Johnson & Johnson and Oxford/AstraZeneca vaccines is now shaken

The call in the US for a pause in the use of the single-shot Johnson & Johnson Covid vaccine is another blow to hopes of vaccinating the whole world as fast as possible.

Health agencies recommended that US states pause use of the jab while investigations take place into six cases of women who have experienced rare blood clotting events combined with low platelets in the days following vaccination.

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How UK doctor linked rare blood-clotting to AstraZeneca Covid jab

Prof Marie Scully developed a diagnostic test at University College London hospital after seeing rare side-effect in patient

Marie Scully was alarmed and puzzled. “It didn’t make sense,” she said. The consultant haematologist at University College London hospital (UCLH) had seen patients with blood clots in the brain and low platelets before and, although it was unusual, she always knew why. But there was no reason for the condition of the young woman in her 30s she was treating in early March.

“Now when you have blood clots in the brain like that there’s always a cause, and it was difficult to pinpoint the cause,” said Prof Scully. “It didn’t fit our normal diagnostic boxes, let’s say. She was a young woman with cerebral venous sinus thrombosis, and she had a low platelet count.”

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Scotland to lift Covid restrictions ahead of schedule

Nicola Sturgeon says ‘Covid is in retreat in Scotland’ as travel and outdoor rules eased

Nicola Sturgeon has accelerated the relaxation of restrictions on travel and outdoor meetings as she said Covid was “in retreat” in Scotland.

Announcing the changes, which will allow Scots to meet up with family and friends across the country outside in larger groups, the first minister said that from this Friday:

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‘We will lose more doctors’: Sudan’s health workers plead for Covid jabs

Country has struggled to get vaccines to frontline medical staff, while Covid toll remains under-reported

More than 200 Sudanese doctors, nurses and medical workers have died from Covid-19, according to sources close to the health ministry – more than three times the official figure.

Like other countries across sub-Saharan Africa, Sudan has struggled to obtain vaccines and distribute them to frontline medical staff. Many of the doctors who have died were senior consultants in their 50s and 60s or older, and so were in high-risk categories.

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African health workers left without Covid jabs as paltry supplies dwindle

Fear of third wave and new variants as sub-Saharan vaccine distribution is dogged by supply disruption

Millions of healthcare workers in sub-Saharan Africa continue to risk their lives to fight Covid-19 as authorities across the continent struggle to obtain and distribute vaccines to frontline medical staff.

Though hundreds of millions of people in western nations are now protected from the virus, doctors, nurses and others on the frontline of the fight against Covid in Africa will have to wait months, or even years, for a vaccine.

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Australia news live: Christine Holgate says she was ‘bullied’ and Australia Post chairman fabricated evidence

Holgate says she was ‘humiliated’ by prime minister Scott Morrison; man dies of coronavirus in Queensland. Follow all the latest news and updates, live
• Australia won’t purchase Johnson & Johnson jab
AstraZeneca blood clotting: what is this rare syndrome?
• Andrew Laming blocked from recontesting next election
More than half of Australians think vaccine rollout is too slow

Wow, it’s been a busy few hours! With that, I’m going to hand you over to Michael McGowan to take you through the rest of the afternoon.

Christine Holgate gave some evidence about executive bonuses. It is a little confusing and we’ll come back to it, because even the senators seem a little confused about what is being said. And it’s important we get it right, so I’ll head back over the transcript to see what she was saying there.

Liberal senator Sarah Henderson has the question call now. She says she has been very moved by Holgate, and what she went through. She asks whether she thinks the questioning on the 22 October estimates hearing was fair.

Holgate:

In all honesty, I didn’t consider whether it was fair or not fair. I absolutely respect and Senator Carr, forgive me but you’ve asked me many tough questions over my time with you (“that’s my job,” Carr says)...and I was about to say ‘that’s your job’.

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‘This is all we could get’: Dutch tourists arrive in Rhodes for locked-down holiday

In experiment organised by Dutch government, travellers will have to take regular Covid tests and are barred from leaving resort

A regime that might, in more normal times, resemble a boot camp has been happily embraced by 189 Dutch tourists who traded lockdown in the Netherlands for eight days of voluntary confinement at a Greek beach resort.

In an experiment devised by travel industry experts determined not to lose another season to Covid-19, the tourists arrived on the Aegean island of Rhodes on Monday as part of a test run to see if safe holidays can be arranged during the pandemic.

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AstraZeneca blood clotting: what is this rare syndrome and how is it caused?

Evidence is growing of a link between the Covid-19 vaccine and a deadly thrombosis – and theories are emerging as to why

Since rare but severe clotting was seen in some people following vaccination with AstraZeneca’s Covid-19 vaccine, researchers worldwide have been grappling to understand why the clotting syndrome, known as “thrombosis with thrombocytopenia” (clotting with a low platelet count), occurs.

Most cases of these clots occurred in veins in the brain (a condition called cerebral venous sinus thrombosis, or CVST), though some occurred in other veins, including those to the abdomen (splanchnic vein thrombosis). It has a high death rate.

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All over-50s and high-risk groups in UK offered vaccine ahead of target date

Achievement hailed by PM as ‘hugely significant milestone’ means people in late 40s should be next to be immunised

All over-50s and high-risk groups in the UK have been offered a coronavirus vaccine a few days before the mid-April deadline set by the government – meaning the second phase of the rollout to younger cohorts can now begin.

Despite fears of a supply slowdown and possible knock in confidence after a change in advice on who could get the Oxford/AstraZeneca jab, Boris Johnson hailed the passing of “another hugely significant milestone”.

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Berlin police investigate possible breach of Covid rules at Soho House party

Video of star-studded event apparently held by Bottega Veneta after Berghain fashion launch shows crowded party and no masks

Berlin police are investigating a possible breach of social distancing rules at an illegal star-studded party said to have been held by luxury fashion label Bottega Veneta, after leaked footage apparently of the event inside private members club Soho House caused outrage in a city whose cherished nightlife has been on hold for ordinary clubbers for over a year.

A presentation of the Italian fashion house’s latest collection at Berlin’s famous and exclusive Berghain nightclub last Friday was reportedly attended by a host of celebrity guests including Nigerian singer Burna Boy.

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A wistful yearning for home and family | Brief letters

Nesrine Malik’s columns | Ex-leaders compared | Love for Guardian letters | A mother’s place

Your columnist Nesrine Malik writes (11 April) that the pandemic has made her reflect wistfully on the bargain she made when she left Sudan to find success far from home. Nesrine’s columns, expressing subtle thoughts with admirable lucidity, have been something I’ve looked forward to reading all during lockdown. Perhaps we in her adopted country are not the audience she most longs for, but her eloquence has surely touched many readers.
Susan Tomes
Edinburgh

• It’s been suggested that there’s little to distinguish between the main parties. But what former leaders do with their time may be instructive: David Cameron’s delayed self-justification for his use of networks to lobby for a company (Report, 12 April) should be weighed against Gordon Brown’s call for the G7 to develop a vaccination plan for the poorest countries (Opinion, 12 April).
Les Bright
Exeter

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Covid pandemic still growing exponentially, WHO says

World Health Organization says ‘confusion and complacency’ prolonging global situation

The global coronavirus pandemic is still growing exponentially, the World Health Organization said on Monday, as it reported 4.4m cases in the last week, the seventh straight week of rising numbers.

The latest global figures represent a 9% increase in infections on last week and a 5% rise in deaths.

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Coronavirus live news: India overtakes Brazil in cases; Italy row over plans for ‘Covid-free’ holiday islands

India now second-worst affected country after US; Sicily and Sardinia criticise plans to prioritise small tourist islands for vaccination

Spain will initially prioritise people aged between 70 and 79 for coronavirus vaccines produced by Johnson & Johnson’s Janssen unit, which are due to start arriving this week.

Reuters reports:

Spain will take a first delivery of 300,000 doses of the single-shot vaccine on Wednesday morning, Carolina Darias told reporters at Gran Canaria airport after a visit to the Spanish Canary Islands.

Johnson & Johnson began delivering its vaccine to EU countries on Monday after some delays due to production issues, European Union officials and the company said.

South Africa’s president Cyril Ramaphosa believes Africa must expand its medical manufacturing capacity and forge partnerships to boost expertise and investment to combat the Covid-19 pandemic and future health emergencies.

Reuters reports:

The continent has struggled to acquire vaccines to fight Covid-19 and imports the vast majority of its medicines and medical equipment, leaving it at the mercy of overseas supplies.

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Spring cold snap hits as England relaxes Covid lockdown restrictions

Snowfall in some areas dampens hopes of businesses reopening their doors for first time in months

The lifting of lockdown restrictions to allow people in England to use pub beer gardens and dine in the outdoor areas of restaurants is being met by snowfall, as a spring cold snap hits.

The inclement weather will come as a blow to thousands of businesses that were hoping to welcome back customers on Monday after months of restrictions.

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Covid vaccine passports: what can we learn from Israel? – video explainer

Israel became the first country in the world to test vaccine passports when it announced the 'green pass' scheme in February. The passes allow people who have had two doses of a Covid-19 vaccine to return to restaurants, theatres and sport events.  With many countries planning to reopen after their vaccination campaigns, the Guardian's Jerusalem correspondent, Oliver Holmes, examines the lessons that could be learned from Israel's rollout

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Ardern tells New Zealand border staff: get Covid vaccine now or be redeployed

Prime minister’s comments come after border worker diagnosed last week said to have missed two vaccine appointments

Border workers have until the end of April to be vaccinated before being moved to lower risk roles, the prime minister, Jacinda Ardern, has said after a third worker from Auckland’s Grand Millenium managed isolation facility tested positive for Covid-19.

“We want everyone to be vaccinated on our frontline,” she told TVNZ’s Breakfast on Monday.

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Covid live: UK nears 40m total coronavirus vaccine doses; Iran records its highest daily death toll this year

UK has now given 32.12 million people a first dose of the vaccine and 7.47 million a second dose; Iran reports 258 further Covid-19 deaths

Gretchen Whitmer, the governor of Michigan, vowed on Sunday to push the Biden administration for more Covid-19 vaccines as her state experiences a worrying spike in cases.

Joe Biden has said Washington will give Michigan more federal resources to support vaccinations and testing, but not additional vaccines.

Related: Michigan governor vows to push Biden for more vaccines as Covid cases surge

China’s top disease control official has admitted that the efficacy of the country’s domestically produced vaccines is low as it emerged the authorities are considering mixing them to try to offer greater protection against coronavirus.

The rare admission of weakness on the part of Beijing’s pandemic approach came from the director of the China Center for Disease Control and Prevention, Gao Fu, who said Chinese vaccines “don’t have very high protection rates”.

Related: Top Beijing official admits efficacy of China’s Covid vaccines is low

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Covid-status certificates could lead to deliberate infections, scientists warn

Immunity certification could foster ‘an erroneous sense of no risk’ in people’s behaviour, according to analysts

Covid-status certificates – to allow those who have been vaccinated, recovered from the virus or have tested negative to attend an event or holiday abroad – could do harm as well as good, UK government science advisers have warned.

While they could encourage some people to get vaccinated, the scientists say others may deliberately go out to get infected, in order to test positive for antibodies and get a certificate enabling them to mix more freely.

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When I was young, I left Sudan in search of ‘success’. Now I yearn for family and home | Nesrine Malik

In the stillness of lockdown, I now see that the costs of globalisation have come to outweigh its benefits

For as long as I have been able to remember, I have known that I would not always live where I was born. I knew that at some point, I would have to leave my country of Sudan if I wanted to secure work that would provide a meaningful living.

At the time, it wasn’t a sad realisation but more an exciting prospect, one that promised a shot at a “modern” life. To me, that modernity meant social mobility, the loosening of oppressive family ties and economic prosperity.

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