Covid vaccines should not be seen as ‘unicorn’ solution, says WHO chief – video

Michael Ryan, the head of the World Health Organization’s emergencies programme, has said that while vaccines are effective tools, they are not the lone solution to ending the coronavirus pandemic.

‘Some people think that vaccines will be, in a sense, the solution, the unicorn we’ve all been chasing,’ he said during a virtual briefing in Geneva on Wednesday, warning other measures such as social distancing needed to be maintained.

It comes after positive efficacy results from late-stage trials of two potential Covid-19 vaccines

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New York City public schools to close again as coronavirus cases rise

  • Closure plan after city reaches 3% Covid test positivity rate
  • Mayor Bill de Blasio: ‘We must fight the second wave’

Public schools in New York City will close again on Thursday, officials announced, after the city reached a 3% Covid test positivity rate.

Related: Covid deaths near 250,000 as US urged to act to stop 'unrelenting' spread

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Norwegian Air files for bankruptcy protection in Ireland

Low-cost airline to continue reduced flight schedule and shares will still be traded in Oslo

Low-cost airline Norwegian Air has filed for bankruptcy protection in Ireland, becoming the biggest casualty of the coronavirus pandemic in the aviation sector to date.

The troubled carrier has asked an Irish court to carry out a process of examinership. This should protect the group’s assets while it tries to slash debt levels and find new funding as part of a restructuring. It is expected to take as long as five months.

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Mayo Clinic: 900 employees at top US hospital catch Covid-19 in two weeks

More than 900 employees at Mayo Clinic, a top research hospital that is based in Rochester, Minnesota, have contracted Covid-19 in the last two weeks.

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Covid-19 mink variants discovered in humans in seven countries

Denmark has already launched a nationwide cull of its farmed mink herd after concerns for vaccine efficacy

Seven countries are now reporting mink-related Sars-CoV-2 mutations in humans, according to new scientific analysis.

The mutations are identified as Covid-19 mink variants as they have repeatedly been found in mink and now in humans as well.

Uncertainty around the implications of the discovery of a Covid-19 mink variant in humans led Denmark, the world’s largest mink fur producer, to launch a nationwide cull earlier this month.

The cull was sparked by research from Denmark’s public health body, the Statens Serum Institut (SSI), which showed that a mink variant called C5 was harder for antibodies to neutralise and posed a potential threat to vaccine efficacy.

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Democratic Republic of Congo declares end to Ebola outbreak

End of 11th outbreak is first time for nearly three years country has been free of Ebola

The Democratic Republic of the Congo has declared an end to its 11th Ebola outbreak, nearly six months after cases were reported.

The end of the outbreak in the western province of Équateur marks the first time that the vast central African nation has been Ebola-free in about two and a half years.

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UK health experts discuss relaxing Covid rules for Christmas – video

Government adviser Dr Susan Hopkins said that community transmission of Covid-19 would have to be low to guarantee a Christmas 'as close to normal as possible'.

The deputy director of Public Health England a said Sage scientific advice indicated that 'for every day that we release (measures) we will need two days of tighter restrictions'

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Covid-19 antibodies reduce faster in men than women – study

Finding has implications for one-size-fits-all approach to vaccine development

Antibody levels against the virus that causes Covid-19 appear to fall faster in men than in women, a study suggests – a finding that could have implications for vaccine research.

Historically, medical research has often taken a one-size-fits-all approach, lumping women and men together despite growing evidence that the sexes differ in how they catch and fight disease. Covid-19 seems to be a case in point, with women more likely to be infected but men thought to be up to twice as likely to die from the virus.

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South Australia to shut down to contain Covid cluster as new national hotel quarantine worker testing rules announced – live news

SA introduces ‘wide-ranging restrictions’ from midnight on Wednesday; $200 vouchers for Victorians to spend in regional areas. Follow the latest news

Insurance companies have lost a crucial test case on whether they have to pay businesses who shut their doors due to the coronavirus pandemic under business interruption policies.

The NSW Court of Appeal says they do, and has thrown out arguments from insurers that coronavirus is excluded from policies.

Meanwhile, a huge chunk of Darwin and surrounds is experiencing a blackout, with the temperature expected to climb to 35C.

Wide spread power outages affecting Darwin and surrounding areas. #DarwinNT Crew responding.

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Coronavirus live news: US doctors urge Trump to share Covid data; record cases in Tokyo

Medical establishment says cooperation can save lives; UK pressed to open transatlantic travel corridors; South Australia locks down for 6 days

I am handing over the blog to my colleague Alexandra Topping in the UK.

Thanks for reading but if you’re just joining, here are the main developments of the past few hours:

Businesses in the Japanese capital, Tokyo, could be asked to shorten their opening hours in order to contain an outbreak of the virus that has seen cases in the city reach a record daily high of 472 on Wednesday.

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How Amazon became a pandemic giant – and why that could be a threat to us all

Online retail grew massively in lockdown, and Amazon reaped huge profits. But where is the company’s relentless innovation and automation heading – and is it time to clip its wings?

For the last year, Anna (not her real name) has been working as an Amazon “associate”, in the kind of vast warehouse the company calls a fulfilment centre. For £10.50 an hour, she works four days a week, though, during busy periods, this sometimes goes up to five. Her shift begins at 7.15am and ends at 5.45pm. “When I get home,” she says, “it’s about 6.30. And I just go in, take a shower and go to bed. I’m always exhausted.”

Anna is a picker in one of the company’s most technologically advanced workplaces, in the south of England. This means she works in a metal enclosure in front of a screen that flashes up images of the products she has to put in the “totes” destined for the part of the warehouse where customer orders are made ready for posting out. Everything from DVDs to gardening equipment is brought to her by robot “drives”: squat, droid-like devices that endlessly lift “pods” – tall fabric towers full of pockets that contain everything from DVDs to toys – and then speed them to the pickers.

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South Australia announces six-day Covid lockdown as ‘circuit breaker’ to avoid second wave

Schools, cafes and pubs to be closed and people asked to stay at home from midnight Wednesday as state’s confirmed cases reach 22

The South Australian government has announced an immediate six-day lockdown followed by a further week of tough restrictions as the state scrambles to avoid a second wave of coronavirus infections.

The lockdown will take effect from midnight on Wednesday after the Parafield cluster, which started from a hotel quarantine breach, grew by two overnight to reach 22 confirmed cases.

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Philippine tradition of ‘long Christmas’ survives Covid and typhoons

Festive season usually last four months but this year as well as the pandemic there have been three strong storms

The strains of Rudolph the Red Nosed Reindeer echo around a popular shopping mall in Quezon City, Manila. A band of mechanical snowmen, dressed in Santa hats, sway back and forth to the music, as shoppers – socially distanced – browse stacks of baubles and Christmas lights.

In the Philippines, a majority Catholic country, festive preparations are well and truly under way already. The country has one of the longest Christmas periods in the world, with celebrations beginning at the start of September and, for some, lasting as late as Valentine’s Day.

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UK music industry will halve in size due to Covid, says report

Growth of 11% in 2019 predicted to reverse this year with collapse of live sector

The UK music industry is set to halve in size this year as issues including an effective shutdown of concerts, gigs and festivals strip £3bn from its contribution to the economy.

UK Music, the umbrella organisation representing the commercial music industry from artists and record labels to the live music sector, has revealed that the industry grew by 11% last year to be worth £5.8bn to the UK economy.

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UK urged to open up transatlantic corridors as ‘Covid-free’ flight arrives

Airlines hope testing passengers pre-departure can remove need for quarantine

Airlines have piled more pressure on the UK government to open up transatlantic air corridors after the first confirmed “Covid-free flight” arrived at Heathrow and the launch of a pre-departure testing trial by British Airways.

A United Airlines flight from Newark arrived at London Heathrow on Tuesday morning having tested all of the passengers onboard to certify them free from coronavirus before departure.

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Covid: near-lockdown curbs imposed on west of Scotland

Eleven local authorities to enter level 4 – highest of Scotland’s five-tier system of virus controls

More than 2.7 million Scots will face near-lockdown restrictions for three weeks after Nicola Sturgeon imposed the country’s highest level of Covid restrictions across the west of Scotland.

Following a cabinet meeting on Tuesday morning, Scotland’s first minister told MSPs that 11 local authority areas would enter level 4 – the highest of Scotland’s five-tier system of virus controls – from 6pm this Friday for a limited period.

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Dolly Parton partly funded Moderna Covid vaccine research

The country music icon’s $1m donation supported the latest breakthrough by Moderna and several research papers

It’s truly the greatest gift of all: a $1m donation by Dolly Parton to coronavirus vaccine research supported the development of the Moderna vaccine, which shows 95% protection from the virus.

In April, Parton donated £800,000 to research after her friend Dr Naji Abumrad of the Vanderbilt Institute for Infection, Immunology and Inflammation at Vanderbilt University in Tennessee told her that they were making “some exciting advancements” in the search for a cure for the virus. Abumrad and Parton became friends in 2014 after the singer was involved in a car accident and treated at Vanderbilt.

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Trump Pennsylvania court hearing due as Biden sharpens criticism of concession refusal – live updates

Gary Younge writes for us today a typically eloquent long read on Donald Trump’s desperate fight to stop the minority vote in 2020 – and how he still lost.

According to Trump, votes were illegitimate by dint of where they were cast. “Detroit and Philadelphia are known as two of the most corrupt political places anywhere in our country – easily,” he said. “They cannot be responsible for engineering the outcome of a presidential race.”

This was a new twist in the racial logic of the American right, which has gone from blocking Black people from voting to allowing them to vote as long as their votes don’t all get counted.

Related: Counted out: Trump's desperate fight to stop the minority vote

In his report on the situation with Iran just now, Patrick Wintour mentioned those reports that Donald Trump is intending to make a significant troop withdrawal from Afghanistan before vacating the White House in January. Nato secretary-general Jens Stoltenberg has issued a warning about that this morning.

Associated Press report him saying “We now face a difficult decision. We have been in Afghanistan for almost 20 years, and no Nato ally wants to stay any longer than necessary. But at the same time, the price for leaving too soon or in an uncoordinated way could be very high,” in a statement.

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UK, Italy and Spain record highest daily death totals since spring – as it happened

This blog is closing now but you can follow our continuing live coverage here. Thanks for reading.

Related: Coronavirus live news: senator Chuck Grassley tests positive; airlines offer Covid testing

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Covid: chemicals found in everyday products could hinder vaccine

Researchers worry PFAS, commonly found in the bodies of Americans, will reduce the immunization’s effectiveness

The successful uptake of any vaccine for Covid-19, a crucial step in returning a sense of normalcy after a year ravaged by the coronavirus pandemic, could be hindered by widespread contamination from a range of chemicals used in everyday products.

Small amounts of per- and polyfluoroalkyl (or PFAS) chemicals are commonly found in the bodies of people in the US, as well as several other countries. These man-made chemicals, used in everything from non-stick pans to waterproof clothes to pizza boxes, have been linked to an elevated risk of liver damage, decreased fertility and even cancer.

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