At least three companies close to revealing results of phase three trials, but to be approved for use safety has to be ensured
The race for a Covid vaccine is reaching a crucial stage, with the glimmer of a possibility that one of the leading contenders will be approved by Christmas.
In an interview with the Guardian, Kate Bingham, who heads the UK’s vaccine taskforce, said the UK was in “a very good place”.
Continue reading...Italy also records 199 further deaths; US record surge killing nearly 1,000 Americans a day; Moscow creates vaccination network
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Merkel said populists who call coronavirus harmless are dangerous; UK furlough scheme to end on Saturday; France reimposes national lockdown
As the row over the discharge of Covid-positive patients into Scotland’s care homes during the early days of the pandemic deepens, health secretary Jeane Freeman has insisted that a new report does not diminish government accountability, writes Libby Brookes, the Guardian’s Scotland correspondent.
The report – which concluded the risk of an outbreak linked to discharge of positive or untested patients was “not statistically significant” - prompted anger from opposition parties, care chiefs and unions, who argued that it failed to properly explain why dozens of patients who tested positive for coronavirus, along with thousands who went untested, were discharged from Scottish hospitals into care homes in April and May.
For relatives and families of people who have died in care homes during this pandemic, I want them to know really clearly that I am not saying that this report says there is no accountability here or that I think that report in any way offers them comfort. It’s a very technical report and it comes to a statistical conclusion but that doesn’t take away from the human impact of this virus…
Angela Merkel faced shouts and heckles in Germany’s parliament this morning as she outlined her government’s plans for a “soft” second lockdown, writes Philip Oltermann, the Guardian’s Berlin bureau chief.
From Monday, bars, restaurants, theatres, swimming pools and fitness studios will close for a month, and public gatherings be limited to two households or up to ten people. Unnecessary travel is discouraged and hotels advised not to host tourists. Schools, nurseries and shops will stay open, however.
Continue reading...Exclusive: expedition discovers new source of greenhouse gas off East Siberian coast has been triggered
Scientists have found evidence that frozen methane deposits in the Arctic Ocean – known as the “sleeping giants of the carbon cycle” – have started to be released over a large area of the continental slope off the East Siberian coast, the Guardian can reveal.
High levels of the potent greenhouse gas have been detected down to a depth of 350 metres in the Laptev Sea near Russia, prompting concern among researchers that a new climate feedback loop may have been triggered that could accelerate the pace of global heating.
Continue reading...German minister warns about exponential rise in new cases; protests against Covid restrictions turn violent in Milan and Turin
One of the world’s leading Covid-19 experimental vaccines produces an immune response in older adults as well as the young, its developers say, raising hopes of protection for those most vulnerable to the coronavirus that has caused social and economic chaos around the world.
Neither Oxford University nor its commercial partner AstraZeneca would release the data from the early trials showing the positive effects, which are being submitted to a peer-reviewed journal. But AstraZeneca confirmed the basic findings about the vaccine it calls AZD1222, which were shared at a closed academic meeting.
Related: Oxford Covid vaccine works in all ages, trials suggest
Structural racism led to the disproportionate impact of the coronavirus pandemic on black, Asian and minority ethnic (BAME) communities in the UK, a review by Dame Doreen Lawrence has concluded.
The report, commissioned by Labour, contradicts the government’s adviser on ethnicity, Dr Raghib Ali, who last week dismissed claims that inequalities within government, health, employment and the education system help to explain why Covid-19 killed disproportionately more people from minority ethnic communities.
Related: Structural racism led to worse Covid impact on BAME groups – report
Continue reading...Chancellor says country is on verge of losing control as Europe death toll passes 250k
The German chancellor, Angela Merkel, has said her country is on the verge of losing control of its fight against the coronavirus pandemic, telling colleagues from her Christian Democratic Union party “the situation is threatening” and “every day counts”.
In leaked comments to an internal party meeting, she told those attending of “very, very difficult months ahead” and added that “every day [would] count” in tackling the virus’s spread.
Continue reading...Proof of significant amounts of H2O has implications for future lunar missions
Scientists have gathered some of the most compelling evidence yet for the existence of water on the moon – and it may be relatively accessible. The discovery has implications for future missions to the moon and deeper space exploration.
With no significant atmosphere insulating it from the sun’s rays, it had been assumed that the moon’s surface was dry – until the 1990s, when orbiting spacecraft found indications of ice in large and inaccessible craters near the moon’s poles.
Continue reading...Restrictions eased in Australian state of Victoria; WHO warns against ‘vaccine nationalism’; Israel to begin first vaccine clinical trials next month. Follow the latest updates
South Korea urged citizens to get vaccinated against influenza and reduce the chances of an outbreak that coincides with the battle against the coronavirus, as it kicked off free inoculations for the last eligible group, Reuters reports.
Public anxiety over the safety of flu vaccines has surged after at least 48 people died this month following vaccinations.
Authorities have said they found no direct link between the deaths and the flu shots and have sought to reassure South Koreans about the safety of the vaccines against flu, a disease that kills at least 3,000 each year.
However, last month, about 5 million doses had to be disposed of after not being stored at recommended temperatures.
Singapore has temporarily halted the use of two influenza vaccines as a precaution after these deaths, becoming among the first countries to publicly announce a halt of the vaccines’ usage. Singapore has reported no deaths linked to flu vaccinations.
India’s total coronavirus infections stood at 7.91 million on Monday, having risen by 45,148 cases in the last 24 hours, health ministry data showed.
The world’s second-most populous country also has the second-highest number of infections after the United States, which has around 8.1 million.
However, India recorded its lowest death toll in about four months on Monday with 480 deaths reported in the last 24 hours, taking total fatalities to 119,014.
Authorities test 2.84 million people after 137 asymptomatic cases found - the first local infections in China since 14 October
China has detected 137 new asymptomatic coronavirus cases in Kashgar in the north-western region of Xinjiang after one person was found to have the virus the previous day – the first new local cases for 10 days in mainland China.
All the cases detected on Sunday were linked to a garment factory where the parents of a 17-year-old girl who was found on Saturday to have the virus – but showed no symptoms – worked, a Xinjiang health commission official told a press briefing.
Continue reading...US expert Dr Anthony Fauci says it should be known by early December if vaccine is safe to roll out
Hopes are rising that a coronavirus vaccine will be approved by the end of the year, with healthcare workers receiving their first dose in early 2021.
Dr Anthony Fauci, the US’s leading expert in infectious diseases, said on Sunday it should be known by the end of November or early December if a vaccine was safe and effective.
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Indonesia reported 4,070 new coronavirus infections on Saturday, taking the total number of cases to 385,980, official data from the country’s Covid-19 taskforce shows.
It also reported 128 new deaths, taking the total to 13,205, and 4,119 people recovered from the virus on Saturday, bringing the total to 309,219.
Wales’ firebreak lockdown should bring the R value - the number of people each coronavirus case infects - below one, health minister Vaughan Gething has said.
Gething told BBC Breakfast the 17-day period would be followed by a set of national measures to control the spread of Covid-19.
Continue reading...After an asteroid encounter, scientists scrambled to minimize the loss of space rocks as the craft belched rubble
A Nasa spacecraft is stuffed with so much asteroid rubble from this week’s grab that it’s jammed open and precious particles are drifting away in space, scientists said on Friday.
Related: Nasa Osiris-Rex spacecraft lands on asteroid Bennu in mission to collect dust
Continue reading...Experts explain the best way to wash masks, how to handle them – and how to prevent ‘maskne’
We hook them on to our faces, laugh, sneeze and sputter into them, then crumple them into our bags or pockets only to retrieve them and do it all again. Yet despite official advice that we should be wearing a fresh face covering each time we enter an enclosed public space, a YouGov poll revealed many people are going several wears between washes – and 15% of Brits don’t wash their reusable masks at all. Similarly, more than half of those opting for disposable masks are rewearing them – 7% of them indefinitely so.
Face coverings are designed to catch the respiratory droplets we emit from our mouths and noses, but given that they’re our own respiratory droplets, is this really so bad? We examine the evidence.
Continue reading...Pedro Sanchez stops short of curfew; Belgium bans fans from sports matches; remdesivir approved by FDA for US
More than half a million people in the US could die from Covid-19 by the end of February next year, but around 130,000 of those lives could be saved if everybody were to wear masks, according to estimates from a modelling study.
The estimates, from a study by researchers at the University of Washington’s Institute for Health Metrics and Evaluation, show that with few effective Covid-19 treatment options and no vaccines yet available, the U.S. faces “a continued COVID-19 public health challenge through the winter”.
Large, populous states such as California, Texas and Florida will likely face particularly high levels of illness, deaths and demands on hospital resources, the study found.
US president Donald Trump’s handling of the coronavirus pandemic, which has killed more than 221,000 Americans so far, has become the top election issue for him and Democratic candidate Joe Biden. Polls have shown that Americans trust Biden more than Trump to handle the crisis.
Filming in Venice of Mission Impossible 7 with Tom Cruise has been temporarily suspended due to a suspected case of Covid among the film crew.
Officially, a reason has not yet been given by the film’s production company, but, according to Italian media reports, the over 100 extras were told there was a suspected case of Covid-19 among the Americans and that, as a result, filming would be postponed to a later date.
Continue reading...Antiviral treatment is first to treat coronavirus approved by FDA; France extends curfew; Study finds between 130,000 and 210,000 US deaths could have been avoided. Follow the latest
Australia’s Victoria state - the epicentre of the country’s Covid-19 outbreak - on Friday reported that active coronavirus cases have fallen to a four-month low, paving the way for an acceleration in the easing of social distancing curbs, Reuters reports.
The nation’s second-most populous state, which recorded just one new infection in the past 24 hours, said there are now 100 active cases - the lowest since 19 June.
“This is a good number. This is a very clear sign that the strategy is working,” Victoria state Premier Daniel Andrews told reporters in Melbourne.
The active infections are a relief to state authorities amid heightened fears of a fresh cluster after a case in a school in Melbourne’s northern suburbs prompted authorities to order 800 people to self-isolate.
However, with new case numbers in single digits for nine consecutive days, Andrews is expected to announce on Sunday an accelerated timetable for easing restrictions in a boost to Australia’s ailing economy.
Melbourne’s roughly 5 million residents were granted more freedom to move about on Monday after a months-long lockdown, but public gatherings remain tightly limited and retailers and restaurants must operate only on take-away or delivery orders.
Australia has recorded just over 27,400 Covid-19 infections, far fewer than many other developed countries. Victoria accounts for more than 90% of the 905 deaths nationally.
Mexico’s health ministry reported on Thursday 6,612 additional cases of the novel coronavirus and 479 more deaths in the country, bringing the official number of cases to 874,171 and the death toll to 87,894.
Health officials have said the real number of infected people is likely significantly higher than the confirmed cases.
Sector calls for compromise to ensure UK researchers stay in Horizon Europe
The UK’s post-Brexit collaboration with European scientists hangs in the balance after it emerged that the EU offer of staying in the Horizon research programme could leave London with a £3bn deficit.
“The financial negotiations are not in a good position and the offer that the [European] commission has made to the UK is not appealing,” Vivienne Stern, the director of Universities UK International, told a Lords Brexit committee on Thursday.
Continue reading...German daily cases rise by 11,287; Wilmès ‘is conscious and can communicate’; France follows Spain in passing 1m infections
The Indian state of West Bengal has reported its biggest daily tally of new Covid-19 infections as thousands of people thronged the streets for a major Hindu festival that began last week, Reuters reports.
India has seen a sharp drop in infections since a September peak, but experts have warned it could see a resurgence during Durga Puja this week, and Diwali, the festival of light, in mid-November.
Croatia, Slovenia and Bosnia have all reported their highest one-day rise in cases, Reuters reports.
Croatia reported its biggest rise in daily new Covid-19 infections on Thursday with 1,563 new cases, nearly half of which were in Zagreb, where they more than doubled. The capital recorded a high of 705 new infections compared with the previous day’s 337 infections. So far, Croatia, a country of some 4 million people, has recorded 29,850 cases with 406 deaths. There are currently 7,380 active cases.
Continue reading...Study links age and number of symptoms to lasting health problems from coronavirus
Women aged 50-60 are at greatest risk of developing “long Covid”, analysis suggests. Older age and experiencing five or more symptoms within the first week of illness were also associated with a heightened risk of lasting health problems.
The study, led by Dr Claire Steves and Prof Tim Spector at King’s College London, analysed data from 4,182 COVID Symptom Study app users who had been consistently logging their health and had tested positive for the virus.
Continue reading...Tiered lockdown system not adequate for preventing high rate of virus infections daily, epidemiologist tells MPs
Tens of thousands of deaths are now inevitable in a second wave of coronavirus infections sweeping across England because of the failure to contain the virus, a government scientific adviser has warned.
John Edmunds, a professor at the London School of Hygiene & Tropical Medicine, told MPs on Wednesday that without further measures England’s tiered Covid-19 strategy would lead to high numbers of new infections every day, putting the NHS under strain and driving up the death toll.
Continue reading...Spain is first western European country to pass milestone; Rome among latest to bring in curfew; German health minister has Covid-19
Four US states reported a record one-day increase in Covid-19 deaths on Wednesday including Wisconsin, a hotly contested state in the 3 November election, as infections keep rising across the Midwest and beyond.
Coronavirus deaths hit daily records in Iowa, Minnesota, Montana and Wisconsin, according to a Reuters analysis. Wisconsin also reported a record daily increase in new cases together with Illinois and Ohio, the analysis showed.
The US is likely to have enough safe and effective Covid-19 vaccines available to inoculate the most vulnerable Americans by the end of 2020, health and human services secretary Alex Azar said.
The US government is “cautiously optimistic” that one or two vaccines, likely from Pfizer or Moderna, will be available by the end of the year and can begin to be distributed to Americans, officials said during a news conference.
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