Scientists win Nobel chemistry prize for ‘genetic scissors’

Emmanuelle Charpentier and Jennifer A Doudna will share the prize for genome editing method

Two women have been awarded the 2020 Nobel prize in chemistry for the discovery of the CRISPR genetic scissors used to edit the DNA of animals, plants and microorganisms with extremely high precision.

Emmanuelle Charpentier and Jennifer A Doudna will share the 10m Swedish kronor (£870,000) prize announced on Wednesday by the Royal Swedish Academy of Sciences in Stockholm – the first time that two women have shared the prize.

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Scientists call for Covid herd immunity strategy for young

Critics describe proposal to isolate vulnerable, disabled and older people as ‘grotesque’

An international group of scientists has called on governments to overturn their coronavirus strategies and allow young and healthy people to return to normal life while protecting the most vulnerable.

The proposal, drawn up by three researchers but signed by many more, argues for letting the virus spread in low-risk groups in the hope of achieving “herd immunity”, where enough of the population is resistant to the virus to quell the pandemic.

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Three scientists share Nobel prize in physics for work on black holes

Roger Penrose says win, shared with Reinhard Genzel and Andrea Ghez, ‘is in some ways a distraction’

Three scientists have won the 2020 Nobel prize in physics for their work on black hole formation and the discovery of a supermassive black hole at the centre of our galaxy.

Sir Roger Penrose, Reinhard Genzel and Andrea Ghez together scooped the 114th Nobel prize in physics.

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Europe must go beyond science to survive Covid crisis, says WHO

Authorities urged to develop policies to tackle ‘virus fatigue’ as Finland, Poland and Russia join nations with rapidly rising cases

The World Health Organization has said European countries will need to “move beyond biomedical science” to overcome Covid-19 as “pandemic fatigue” and new infections rapidly rise across the continent.

Hans Kluge, the WHO’s Europe director, said that while fatigue from months of uncertainty and disruption was measured differently in different countries, aggregated survey data from across the region suggested that in some cases it it had reached levels of over 60%.

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Coronavirus live news: Belgium limits gatherings to four people; Italy set to make masks mandatory outdoors

‘People are tired, we know,’ says Belgian PM of new measures; Lazio and Campania already enforcing face-covering rules

Reuters reports that US cruise operator Royal Caribbean Cruises Ltd has extended suspension of sailings until 30 November, excluding those originating from Hong Kong, as the Covid-19 crisis continues to hurt the demand for voyages.

The company said its cruise brand Celebrity Cruises will suspend its 2020-21 winter program in Australia and Asia, while its Azamara cruises will suspend winter sailings throughout Australia and New Zealand, South Africa and South America.

The US Democratic presidential nominee Joe Biden tested negative for Covid-19 in a test conducted on Tuesday, his campaign said in a statement.

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Dogs’ brains ‘not hardwired’ to respond to human faces

Study of brain activity shows no difference when dogs see back or front of a head

Dog owners might love their pet’s endearing puppy dog eyes and cute furry features, but it turns out the doggy brain is just as excited by the back of our heads as the front.

For despite having evolved facial expressions that tug on the heartstrings of owners, researchers have found that unlike humans, dogs do not have brain regions that respond specifically to faces.

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Lana Del Rey criticised for wearing mesh mask to poetry reading

Musician posed with fans at a Los Angeles bookshop wearing a glittery mesh mask that did not fully cover her nose and mouth

Fans of Lana Del Rey have criticised her for wearing a glittery mesh mask that did not appear to fully cover her nose and mouth at a surprise poetry reading and book signing event.

The musician read from her new collection, Violet Bent Backwards Over the Grass, and posed with fans at a Barnes and Noble store in Los Angeles at the weekend, wearing a net facial covering that did not seem to assist in preventing the spread of the coronavirus.

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Did early focus on hand washing and not masks aid spread of Covid-19?

Increasing number of scientists believe risk from contaminated surfaces may have been overplayed

From the moment coronavirus reached UK shores, public health advice stressed the importance of washing hands and deep-cleaning surfaces to reduce the risk of becoming infected.

The advice was informed by mountains of research into the transmission of other respiratory viruses: it was the best scientists could do with such a new pathogen.

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Coronavirus live news: global cases pass 35m as Walter Reed physician calls Trump drive ‘insanity’

UK reports 22,961 new cases, says figure ‘artificially high’; nine New York neighbourhoods headed for lockdown; Ireland health experts recommend moving to highest level. Follow the latest updates

In non-coronavirus news, the number of confirmed coronavirus cases in Germany increased by 1,382 to 300,619, data from the Robert Koch Institute (RKI) for infectious diseases showed on Monday.

The reported death toll rose by five to 9,534, the tally showed.

The New York Times, citing medical experts, reported on Sunday that Trump’s medical treatments suggest that the president has a “severe” case of Covid-19.

The times report, which asks several doctors to decipher how ill Trump may be – amid confusing and contradictory reports from his medical staff and the White House – based on the treatments he is taking.

Some experts raised an additional possibility: that the president is directing his own care, and demanding intense treatment despite risks he may not fully understand. The pattern even has a name: V.I.P. syndrome, which describes prominent figures who receive poor medical care because doctors are too zealous in treating them — or defer too readily to their instructions.

Regeneron’s monoclonal antibody therapy: On Friday afternoon, the White House said in a letter that Trump was treated with an 8-gram dose of the experimental antibody therapy cocktail made by the biotechnology company Regeneron. The investigational cocktail, known by its investigational name REGN-COV2, has been in clinical trials since June.

Remdesivir: President Trump is being given a five-day course of the antiviral drug remdesivir, one of the doctors treating him said during a briefing on Saturday. The treatment is intended to shorten recovery time for Covid-19 patients. In a Phase 3 clinical trial, remdesivir was found to speed recovery in moderately ill patients with pneumonia from Covid-19, according to results published in the medical journal JAMA in August.

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Coronavirus live news: Irish government ‘to reject new lockdown recommendation’; Paris bars to close

Ireland’s health chiefs called for highest level of restrictions late on Sunday; restaurants in Paris can stay open but bars cannot

French health authorities have reported that the number of patients being treated in intensive care units (ICUs) for Covid-19 has gone beyond the 1,400 threshold for the first time since 28 May.

The latest figure comes the day before Paris is to be placed on maximum Covid-19 alert, meaning bars will be forced to close for two weeks, partly because of the sharp rise of the number of people in ICUs.

Argentine soccer legend Diego Maradona has been tested for the coronavirus, his lawyer said on Twitter on Monday.

The results of the former striker’s test are expected within 24 hours, his lawyer Matias Morla said. Morla shared a photo of a medical worker swabbing Maradona at his home.

Cumpliendo con los protocolos y para tranquilidad de Diego y de su familia, Maradona fue hisopado este mediodia en su domicilio. Los resultados estarán en las próximas 24 horas. pic.twitter.com/BTCLVgyc0c

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Trump’s steroid Covid treatment adds to confusion over health

Dexamethasone ‘normally reserved for people going into respiratory failure’, says expert

The latest intervention from Donald Trump’s medical team has been to put the president on dexamethasone, a steroid that is proven, thanks to the UK’s Recovery trial, to benefit Covid-19 patients who are having breathing difficulties.

But the decision to administer the steroid now has only added to the confusion surrounding the president’s state of health. Normally, dexamethasone is reserved for patients who have been ill for at least a week and whose oxygen levels are low.

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Trump will come through Covid well, says Boris Johnson – live news

Attention has turned to the White House ceremony where Donald Trump named his supreme court nominee as a potential super spreader event

China’s president, Xi Jinping, has joined world leaders in sending a message of sympathy to Donald and Melania Trump following their coronavirus diagnosis.

“My wife, Peng Liyuan, and I express our sympathies to you and your wife and wish you a fast recovery,” Chinese state media cited the message as saying.

North Korea’s leader, Kim Jong-un, has sent a message of sympathy to Donald Trump and his wife, Melania, expressing his hope that they will recover from coronavirus, state media reported.

“He sincerely hoped that they would recover as soon as possible. He hoped they will surely overcome it,” the Korean Central News Agency reported. “He sent warm greetings to them.”

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Malaria campaigns fight off Covid disruptions to deliver programmes

Almost all planned work against the disease has gone ahead this year, delivering nets, drugs and the world’s first malaria vaccine

More than 90% of anti-malaria campaigns planned this year across four continents are on track, despite disruptions caused by the coronavirus pandemic, according to new research.

The delivery of insecticide-treated nets and provision of antimalarial medicines in the majority of malaria-affected countries across Africa, Asia and the Americas were still going ahead, a high-level meeting organised by the RBM Partnership to End Malaria heard on Thursday.

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Trump’s positive Covid test was a surprise that many saw coming

The president has been cavalier throughout the coronavirus pandemic. Now, a month before the election, this changes everything

It is likely to go down as the biggest “October surprise” in the history of US presidential elections. Yet anyone who was paying attention could have seen it coming.

Donald Trump tested positive for the coronavirus after claiming “it will disappear”, telling the journalist Bob Woodward he was downplaying it deliberately, failing to develop a national testing strategy, refusing to wear a face mask for months, floating the idea of injecting patients with bleach, insisting to one of his many crowded campaign rallies that “it affects virtually nobody” and, at Tuesday’s debate, mocking his rival, Joe Biden: “He could be speaking 200 feet away and he shows up with the biggest mask I’ve ever seen.”

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Coronavirus live news: Paris faces being placed on ‘maximum alert’ as India nears 100,000 deaths

Bars and restaurants in Paris face closure from Monday; Turkey condemned for underreporting cases; Scottish National Party lawmaker suspended after travelling by train despite positive test. Follow the latest updates

In the UK, strictly Come Dancing contestant HRVY has tested positive for coronavirus, just over two weeks before the launch of the new series.

The singer and YouTube star, whose real name is Harvey Leigh Cantwell, announced the news on social media, telling fans he does not have any symptoms and is now isolating for 10 days.

Related: Strictly Come Dancing contestant HRVY tests positive for Covid-19

The death toll in India, which has the second-highest number of cases worldwide, is nearing the grim milestone of 100,000. There are currently 98,678 deaths confirmed on the Johns Hopkins University tracker.

India’s deaths are the third-highest worldwide, after Brazil with 143,952 and the US with 207,651.

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Coronavirus live news: WHO approves new rapid Covid test; Madrid to enter partial lockdown

Health body gives green light to second test that gives results in up to 30 minutes; Spanish capital is Europe’s worst hotspot

France reported 12,148 new Covid-19 infections over the past 24 hours, the French health ministry said.

Friday’s figure is lower than Thursday’s 13,970 and well below highs of over 16,000 seen last week.

The Democratic presidential candidate, Joe Biden, and his wife, Jill, have tested negative for coronavirus, their doctor said in a statement on Friday.

“Vice-president Joe Biden and Dr Jill Biden underwent PCR testing for Covid-19 today and Covid-19 was not detected,” Dr Kevin O’Connor said in a statement.

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Covid-19 vaccine alone won’t defeat spread of virus, report warns

Issues over production, efficacy and public trust mean restrictions may be needed for some time

A successful vaccine for Covid-19 will not conquer the spread of the virus alone, with restrictions on daily life likely to continue for some time, a team of experts have said.

Hundreds of teams of researchers around the world are working to produce a vaccine against the coronavirus, with 11 currently in phase three human trials. The UK government has reserved access to six potential vaccines and has raised hopes that a vaccine could be on the cards by spring next year.

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Covid-19 live news: Madrid lockdown looms; Italy’s PM proposes extending state of emergency

Africa approaching 1.5m cases across its 54 countries; Italy could extend government powers to January; record cases high in Ukraine

Sweden has registered its highest daily Covid caseload since June, with 752 new infections recorded on Thursday, though no new related deaths have been recorded.

The Scandinavian country has shunned lockdowns, leaving most schools, restaurants and businesses open throughout the pandemic. Thursday’s rise was the highest since 30 June, when the health agency recorded just over 800 new cases.

The mayor of Moscow, Sergei Sobyanin, has said infections in Russia’s capital are rising by about 2,000 a day, and ordered employers to transfer at least 30% of staff to remote work.

Writing on his blog, Sobyanin said the rate of Covid-19 hospitalisations was also rising by around 5,000 per week.

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Neanderthal genes increase risk of serious Covid-19, study claims

Strand of DNA inherited by modern humans is linked to likelihood of falling severely ill

Modern humans and Neanderthals could be forgiven for having other issues on their minds when they interbred in the stone age. But according to researchers, those ancient couplings laid a grim foundation for deaths around the world today.

Scientists have claimed that a strand of DNA that triples the risk of developing severe Covid-19 was passed on from Neanderthals to modern humans. The genetic endowment, a legacy from more than 50,000 years ago, has left about 16% of Europeans and half of South Asians today carrying these genes.

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