Scientist who edited babies’ genes says he acted ‘too quickly’

Exclusive: He Jiankui stops short of apologising for procedure that shocked the world of science in 2018

The scientist at the heart of the scandal involving the world’s first gene-edited babies has said he moved “too quickly” by pressing ahead with the procedure.

He Jiankui sent shock waves across the world of science when he announced in 2018 that he had edited the genes of twin girls, Lulu and Nana, before birth. He was subsequently sacked by his university in Shenzhen, received a three-year prison sentence, and was broadly condemned for having gone ahead with the risky, ethically contentious and medically unjustified procedure with inadequate consent from the families involved.

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Bear-clawed cavern discovered in Spain ‘opens new door on prehistory’

Researchers hail ‘world-class discovery’ that suggests cave bears may have lived farther south than thought

Researchers exploring a cave system in south-east Spain have discovered a huge cavern, sealed off for millennia, hung with huge stalactites and gouged by the claws of long-extinct cave bears, which, they claim, “opens a new door on prehistory”.

The find was made at the Cueva del Arco, a collection of caves in the Almadenes gorge near the Murcian town of Cieza. Although the site had already yielded evidence of settlements stretching back 50,000 years – making it one of the few places in the eastern Iberian peninsula where the transition from Neanderthals to modern humans can be documented – experts digging there suspected it harboured further discoveries.

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Blobs of human brain planted in rats offer new treatment hope

Scientists suggest patient’s own cells could be grown in the lab and used to repair stroke or trauma injuries

Blobs of human brain tissue have been transplanted into the brains of rats in work that could pave the way for new treatments for devastating brain injuries.

The groundbreaking study showed that the “human brain organoids” – sesame seed-sized balls of neurons – were able to integrate into the rat brain, linking up with their blood supplies and communicating with the rat neurons.

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NSW irrigator hit with $350,000 fine for water theft offences

Moree Plains company found guilty of knowingly taking water with faulty metering equipment for crops such as cotton

A Moree Plains irrigator has been ordered to pay a record $350,000 in fines after pleading guilty to knowingly taking water, using an under-recording meter system and constructing an unlawful dam.

It is the first time a “tier one” offence has been successfully prosecuted by the Natural Resources Access Regulator (NRAR).

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‘Charmouth crocodile’ identified as new genus of croc-like creature

Remains of 2-metre-long animal were discovered in 2017 by two fossil hunters for whom it has been named

Scientists have identified a new genus of fearsome crocodile-like creature that once hunted off what is now Dorset’s Jurassic Coast.

The remains of the 2-metre-long animal were discovered by fossil hunters after a series of landslips on to a beach in 2017, and the newly recognised beast has been named Turnersuchus hingleyae in honour of the finders, Paul Turner and Lizzie Hingley.

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Bizarre ‘whirlpool’ appears in night sky above Hawaii

Phenomenon believed to have origins in launch of military GPS satellite from SpaceX in Florida

A camera on top of Hawaii’s tallest mountain has captured what looks like a spiral swirling through the night sky.

Researchers believe the strange phenomenon is linked to a military GPS satellite that launched from a SpaceX rocket in Florida.

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Three or more concussions add up to long-term cognitive problems, study suggests

Multiple concussions in a lifetime were shown to affect the ability to plan and pay attention, though research also underlined health benefits of playing sport

Experiencing multiple concussions may be linked to worse brain function in later life, suggests a study of nearly 16,000 people.

Among 15,764 people aged 50 to 90, those who reported three or more concussions had worse complex planning and attention scores on a range of cognitive tests.

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Plant toxin hailed as ‘new weapon’ in antibiotic war against bacteria

Scientists say albicidin has allowed them to take a giant step forward to creating a powerful new range of antibacterial drugs

Scientists have discovered a plant toxin whose unique method of dispatching bacteria could be used to create a powerful new range of antibiotics. The prospect of developing new antibacterial drugs this way has been hailed by doctors, who have been warning for many years that the steady rise of multidrug-resistant pathogens such as E coli now presents a dangerous threat to healthcare across the planet.

The new antibiotic – albicidin – attacks bacteria in a completely different way to existing drugs, a group of British, German and Polish scientists have revealed in a paper recently published in the journal Nature Catalysis. This suggests a new route could be exploited to tackle bacterial disease, they say.

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‘Remarkable’: Eastbourne shipwreck identified as 17th-century Dutch warship

Klein Hollandia discovery ‘opens up fascinating chapter in rich, shared maritime history between UK and Netherlands’

Shipwrecked: how tech is revealing world of 3m lost vessels

A remarkably preserved shipwreck known only as the “unknown wreck off Eastbourne” has finally been identified as the 17th-century Dutch warship Klein Hollandia which was involved in all the big battles in the second Anglo-Dutch war.

Its identity has been confirmed after painstaking research by archeologists and scientists after its initial discovery in 2019, having lain 32 metres (105ft) underwater on the seabed since 1672.

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US moves to simplify Covid vaccines into yearly dose to target variants

The FDA asked its scientific advisers on Thursday to help chalk out plan to move to a flu shot-like schedule for coronavirus

The US is poised to make Covid-19 vaccinations more like a yearly flu shot, a major shift in strategy despite a long list of questions about how to best protect against a still rapidly mutating virus.

The Food and Drug Administration asked its scientific advisers on Thursday to help lay the groundwork for switching to once-a-year boosters for most Americans – and how and when to periodically update the shots’ recipe.

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Feline uncertain? Cats do give clues if the fur’s about to fly, study finds

Study of 105 pairs of interacting felines decodes the cat behaviour that puzzles humans – and flags up the unsubtle battle cry of claws and yowling

When cats get together it can be difficult to tell rough and tumble play from a full-blown scrap. Now researchers say they have decoded feline behaviour to help owners spot when the fur might be about to fly.

Dr Noema Gajdoš‑Kmecová, first author of the research from the University of Veterinary Medicine and Pharmacy, in Košice, Slovakia – a cat owner herself – said understanding feline interactions could be difficult.

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Archaeologist hails possibly oldest mummy yet found in Egypt

The 4,300-year-old mummy was found at the bottom of a 15-metre shaft near the Step Pyramid at Saqqara

Egyptologists have uncovered a Pharaonic tomb near the capital, Cairo, containing what may be the oldest and most complete mummy yet to be discovered in the country, the excavation team leader has said.

The 4,300-year-old mummy was found at the bottom of a 15-metre shaft in a recently uncovered group of fifth and sixth dynasty tombs near the Step Pyramid at Saqqara, Zahi Hawass, director of the team, told reporters.

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Dark energy ‘chameleon trap’ wins £100,000 prize for Nottingham scientist

Ingeniously simple lab experiment led by Prof Clare Burrage recognised by Blavatnik awards

Dark energy is the enigma at the heart of modern physics: the universe is supposed to be awash with the stuff, but it has never been seen and its nature is unknown.

When faced with a mystery of such epic proportions, simply eliminating certain options is considered a success. This week such an advance, using an ingeniously simple desktop experiment, was recognised by the prestigious Blavatnik award for young scientists.

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Xi’s authority dented by sudden Covid U-turn but iron grip on power is undimmed

Analysts say Xi has consolidated power so successfully that he is in effect the Communist party. With no opposition, it doesn’t matter if he makes mistakes

Just a few months ago, the thought of questioning the strength of Xi Jinping’s leadership was inconceivable. He had just secured his third term, conducted a brutal purge of factional rivals and ensured he and his beliefs were inextricably and existentially tied with the Chinese Communist party. The zero-Covid policy – despite some societal grumblings – had been enshrined as the best and only way out of the pandemic.

But zero Covid was already growing unpopular in China in the latter half of 2022. It was playing havoc with people’s lives with increasing lockdowns and quarantines, and a string of tragedies had been linked to the policy’s enforcement. Then in early December, after protests in major Chinese cities and rising cases of Omicron, the government suddenly ended the policy. Travel restrictions, quarantines, mandatory tests and other restrictions were drastically scaled back or dropped altogether.

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Thousands at risk of heart attacks due to Covid disruption, experts warn

Patients in England, Scotland and Wales missed out on starting blood pressure-lowering drugs, British Heart Foundation says

Thousands of people are at risk of avoidable heart attacks and strokes, experts have warned, after nearly 500,000 people in England, Scotland and Wales missed out on starting blood pressure-lowering drugs during the pandemic.

Researchers said that thousands of people could suffer a preventable cardiovascular event because they did not start taking vital medications known to stave off deadly heart and circulatory diseases amid the Covid related disruption to healthcare.

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England’s PCR Covid testing network drops one of three labs as demand falls

Rosalind Franklin laboratory in Leamington Spa no longer to be part of laboratory network processing Covid tests

England’s PCR testing network for Covid is to be scaled back due to a fall in demand, public health officials have said.

The UK Health Security Agency (UKHSA) said that the Rosalind Franklin laboratory in Leamington Spa – which at its peak was processing about 75,000 Covid PCR tests a day – will cease to operate as part of the processing network.

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US government logs more than 500 UFO reports with hundreds unexplained

Although many are attributed to drones or balloons, others point to the spying capabilities of rival nations

The US government is examining 510 UFO reports, more than triple the number in its 2021 file. While many were caused by drones or balloons, hundreds remain unexplained, according to a report released on Thursday.

The 2022 report (pdf) by the Director of National Intelligence (DNI) said that 247 “unidentified anomalous phenomena” or UAP reports have been filed with it since June 2021, when it revealed that it had records of 144 sightings of suspicious aerial objects under examination.

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Researchers warn of potentially fatal condition for open-water swimmers

Swimming-induced pulmonary oedema involves the accumulation of fluid in the lungs of swimmers without it having been inhaled

A potentially life-threatening condition that can affect fit and healthy open-water swimmers causing them to “drown from the inside” may involve a buildup of fluid in the heart muscle, researchers have suggested.

Swimming-induced pulmonary oedema – SIPE – is a form of immersion pulmonary oedema and involves the accumulation of fluid in the lungs of swimmers without it having been inhaled. The condition is thought to be a result of increased pressure on the body’s blood vessels as a result of exertion, immersion and cold.

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UK’s first orbital rocket mission takes off from Cornwall

Virgin Orbit’s Start Me Up mission heralded as start of new space era as Boeing 747 to deliver rocket carrying satellites into orbit

A historic rocket mission has set off from Cornwall as a specially converted Boeing 747 heads out over the Atlantic carrying a payload of nine satellites that it will propel into orbit.

Virgin Orbit’s Start Me Up mission is the first launch of satellites from European soil and is being heralded as the start of a new space era for the UK.

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Thousands expected in Cornwall for Europe’s first satellite launch

Start Me Up mission will send nine civil and defence satellites into orbit from Newquay spaceport on Monday

Thousands of people are expected to descend on Cornwall to witness the first orbital rocket launch from UK soil in what is being heralded as the start of a “new era” for the British space industry.

As long as there are no last-minute technical hitches – and the Cornish weather does not spoil the party – the historic Start Me Up mission will take off on Monday night from Spaceport Cornwall, blasting nine satellites into orbit.

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