Covid-19 virus does not infect human brain cells, study suggests

Exclusive: study raises hopes that Covid-related damage to sense of smell may be more superficial than previously feared

The virus that causes Covid-19 does not infect human brain cells, according to a study published in the journal Cell. The findings will raise hopes that the damage caused by Sars-CoV-2 might be more superficial and reversible than previously feared.

The study contradicts earlier research that suggested the virus infects neurons in the membrane that lines the upper recesses of the nose.

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Europe’s record summer ‘impossible’ without global heating

Cop26 countries must take action to stop record heat becoming an annual event, say experts

The heatwaves and wildfires that caused devastation in Europe this summer would not have happened without global heating, new analysis shows.

The summer of 2021 was the hottest on record in the continent, with average temperatures about 1C above normal. The elevated heat caused wildfires and premature deaths.

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Flu, cancer, HIV: after Covid success, what next for mRNA vaccines?

The technology was viewed with scepticism before the pandemic but there is now growing confidence about its use

It is one of the most remarkable success stories of the pandemic: the unproven technology that delivered the Moderna and Pfizer/BioNTech vaccines in record time, helping to turn the tide on Covid-19. The vaccines are based on mRNA, the molecule that instructs our cells to make specific proteins. By injecting synthetic mRNA, our cells are turned into on-demand vaccine factories, pumping out any protein we want our immune system to learn to recognise and destroy.

Pre-pandemic, the technology was viewed with scepticism – a clever concept, but not guaranteed to deliver. Now there is growing confidence that mRNA vaccines could have far-reaching applications in tackling diseases from flu to malaria.

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‘We are protected by prayers’: the sects hampering southern Africa’s vaccine rollout

With millions of followers, the stance of some Apostolic church leaders threatens to undermine fight against Covid

Hymnal melodies reverberate around the hillside in Kuwadzana, a Harare suburb. On a blisteringly hot Saturday, members of the Apostolic church, dressed in white, hum and sing together.

Songs, long prayers and a little Bible reading punctuate the outdoor service. It’s a spectacle for passersby.

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‘Vax’ chosen as word of the year by Oxford English Dictionary firm

Accolade reflects how use of the short form of ‘vaccine’ rose by 72 times in a year and spread across society

In a year when talk over the virtual garden fence has focused on whether you have been jabbed, jagged or had both doses yet, and whether it was Pfizer, AstraZeneca or Moderna you were injected with, Oxford Languages has chosen vax as its word of the year.

After deciding last year that it was impossible to sum up 2020 in one word, the company that produces the Oxford English Dictionary said the shorthand for vaccine had “injected itself into the bloodstream of the English language” this year during the Covid pandemic.

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New evidence suggests Vikings – and their mice – beat Portugal to the Azores

Evidence from animal remains shows Norse seafarers settled on the islands centuries before Portuguese explorers

They came from the land of the ice and snow and the midnight sun – but still ended up in some balmy destinations. This is the conclusion of researchers who have discovered evidence to support the idea that the Vikings settled on the clement shores of the Azores several hundred years before the Portuguese arrived in 1427.

Given that the Vikings are usually associated with the frozen north, the claim is startling. Nevertheless, it is based on solid science, says a group of international researchers who recently analysed lakebed sediments in the Azores, an archipelago in the mid-Atlantic.

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Burn, baby, burn: the new science of metabolism

Losing weight may be tough, but keeping it off, research tells us, is tougher – just not for the reasons you might think

As the director of the Energy Metabolism Laboratory at Tufts University, Massachusetts, Susan Roberts has spent much of the past two decades studying ways to fight the obesity epidemic that continues to plague much of the western world.

But time and again, Roberts and other obesity experts around the globe have found themselves faced with a recurring problem. While getting overweight individuals to commit to shedding pounds is often relatively straightforward in the short term, preventing them from regaining the lost weight is much more challenging.

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Prof Peter Stott: ‘Denialists question the cost of climate action … doing nothing costs far more’

The veteran scientist on Trump’s limited impact, Russia’s ruthless climate stance and on the urgency of COP26 in Glasgow

Prof Peter Stott is a forensic climate detective who examines the human fingerprint on extreme weather. A specialist in mathematics, he leads the climate monitoring and attribution team of the Hadley Centre for Climate Science and Services at the Met Office in Exeter and was part of the UN Intergovernmental Panel on Climate Change team that won the Nobel peace prize in 2007. Since he started in the field more than 25 years ago, Stott has often found himself on the frontline of the battle against the fossil fuel lobby, petrostates and sceptical rightwing US politicians, which he details in his new book. Hot Air: The Inside Story of the Battle Against Climate Change Denial. He is also exploring new forms of scientific expression and is co-founder, with his wife, of the Climate Stories initiative, which brings artists, scientists and members of the public together to respond to the climate emergency by creating new poems, songs and pictures.

You have spent a quarter of a century in climate science. On a personal level, how does that feel?
At times I have felt exhilarated about the progress of our science and hopeful that it will be acted on. In other moments, I felt dispirited that our warnings were ignored, such as at Copenhagen in 2009, or worried when we were attacked as in Moscow in 2004, or in the US and UK after Climategate. At those times, I felt I was uncovering an uncomfortable truth and there were people who were literally trying to stop me from saying it. Now I feel anxious that the clock is ticking on the whole issue. Another very hot year has gone by and there is no sign of action that is sufficient to change the data trends. That makes me concerned about the science I have spent 26 years doing. I hoped this work would make the world a better place, but I am increasingly anxious that this will not happen in time.

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‘Yeah, we’re spooked’: AI starting to have big real-world impact, says expert

Prof Stuart Russell says field of artificial intelligence needs to grow up quickly to ensure humans remain in control

A scientist who wrote a leading textbook on artificial intelligence has said experts are “spooked” by their own success in the field, comparing the advance of AI to the development of the atom bomb.

Prof Stuart Russell, the founder of the Center for Human-Compatible Artificial Intelligence at the University of California, Berkeley, said most experts believed that machines more intelligent than humans would be developed this century, and he called for international treaties to regulate the development of the technology.

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Fresh air or foul odour? How Covid can distort the sense of smell

Coronavirus-induced parosmia is surprisingly common and the sensory confusion can have profound effects

Deirdre likens her body odour to raw onions; Deepak says his favourite aftershave smells foul, and coffee like cleaning products; Julie thinks coffee and chocolate both smell like burnt ashes.

Most people are aware that a cardinal symptom of Covid-19 is loss of smell, or anosmia. It may last for weeks or even months. Increasingly though, those who have recovered subsequently develop another disorienting symptom, parosmia, or a distorted sense of smell. This typically results in things that once smelled pleasant smelling bad or rotten.

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Call for action on TB as deaths rise for first time in decade

Tuberculosis campaigners tell G20 leaders $1bn is needed annually for vaccine research to reverse decades of underfunding

A group of tuberculosis survivors are calling for more funding and action to find new vaccines, after the numbers dying of the infection rose for the first time in 10 years.

In 2020, 1.5 million were killed by TB and 10 million infected, according to the World Health Organization. Campaigners want world leaders to invest $1bn (£730m) every year into vaccine research, spurred on by the momentum from the Covid jab development.

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‘I’m scared I’ve left it too late to have kids’: the men haunted by their biological clocks

It’s certainly not just women who worry about ageing and procreation – and now men have begun speaking about their own deep anxieties

It was when Connor woke up in the middle of the night to go to the bathroom that he started thinking about it. The 38-year-old civil servant from London got back into bed and couldn’t sleep: he was spiralling. “I thought: ‘Shit, I might not be able to have children. It actually might not happen,’” he says.

“It started with me thinking about how I’m looking to buy a house, and everything is happening too late in my life,” Connor says. “Then I started worrying about how long it would take me to save again to get married, after I buy the house. I was doing the maths on that – when will I be able to afford to be married, own a house and start having kids? Probably in my 40s. Then I started freaking out about what the quality of my sperm will be like by then. What if something’s wrong with the child? And then I thought, oh no, what if me and my girlfriend don’t work out? I’ll be in an even worse scenario in a few years.”

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Why pregnant women need clearer messaging on Covid vaccine safety

Analysis: early uncertainty around vaccination advice for expectant mothers has left them confused and hesitant

In the early stages of the coronavirus pandemic, there was uncertainty around almost everything, from who was more adversely affected by Covid-19 to who should get vaccinated first – or at all.

But as awareness about the illness and vaccine safety has grown, one group in particular remains confused and torn about the risk of immunisation: expectant mothers.

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Astronomers spot first possible exoplanet outside our galaxy

Saturn-sized planet candidate has been identified in Whirlpool Galaxy 28m light years away

A possible Saturn-sized planet identified in the distant Whirlpool Galaxy could be the first exoplanet to be detected outside the Milky Way.

The exoplanet candidate appears to be orbiting an X-ray binary – made up of a normal star and a collapsed star or black hole – with its distance from this binary roughly equivalent to the distance of Uranus from the sun.

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The psychology of masks: why have so many people stopped covering their faces?

In England, masks are expected and recommended in crowded and enclosed spaces – but not legally required. Many have abandoned them altogether. What would convince everyone to put them back on?

Dave stopped wearing his face mask “the second I didn’t have to. I grudgingly wore it, because it was the right thing to do and because it was mandatory,” says the teacher from East Sussex. “But I felt, and still do, that the reason we were told to wear masks was to make scared people feel less scared.” He didn’t feel awkward abandoning his mask, he says, as “hardly anybody bothers”, but he will put one on when visiting the vet, pharmacist or doctor, because he knows they want him to. “I feel it’s the respectful thing to do, but it’s a bit of theatre.”

Every month since July, when the legal requirement to wear face masks – along with other restrictions – ended in England, the number of mask-wearers has dropped. In figures released by the Office for National Statistics (ONS) last week, 82% of adults reported they had worn a mask outside their home in the previous seven days – a drop from 86% the previous month. But that seems high to me. In my own highly unscientific survey of people coming out of a shopping centre in a south coast town centre last week, only around one in 25 were wearing a mask and overwhelmingly they tended to be older people – the most vulnerable social group. “When everyone else stopped, I stopped,” says Holly. Her friend Chantelle works in a supermarket and also hasn’t worn a mask since July. Does she mind customers not wearing masks? “Not really,” she says, “because I’m not wearing one. Doing an eight-hour shift in it was horrible.” Would they go back to wearing masks? “If we had to, then yeah, I would,” says Holly, but neither would by choice.

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Why people believe Covid conspiracy theories: could folklore hold the answer?

Researchers use AI – and witchcraft folklore – to map the coronavirus conspiracy theories that have sprung up

Researchers have mapped the web of connections underpinning coronavirus conspiracy theories, opening a new way of understanding and challenging them.

Using Danish witchcraft folklore as a model, the researchers from UCLA and Berkeley analysed thousands of social media posts with an artificial intelligence tool and extracted the key people, things and relationships.

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The world was woefully unprepared for a pandemic. Let’s be ready for the next one | Elhadj As Sy

The Global Preparedness Monitoring Board is calling for a coherent action plan to counter future health emergencies

Two years ago, three months before coronavirus erupted, the Global Preparedness Monitoring Board (GPMB) issued a warning to the international community that a pandemic was only a matter of time, and that the world was not prepared. Tragically, we were proved right.

After 20 months of Covid-19, with nearly five million directly attributed deaths and economic devastation, we say again that the world is not prepared. It has neither the capacity to end the current pandemic in the near future, nor to prevent the next one.

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David Frost says EU close to breaching Brexit deal over science programme

Minister ‘quite concerned’ about delay to finalising UK’s participation in €80bn Horizon Europe scheme

A fresh Brexit row has been blown open with Brussels after David Frost accused the EU of being close to breaching the trade deal struck last Christmas.

He said the UK was “getting quite concerned” about Brussels delaying ratification of the UK’s participation in the €80bn (£67bn) Horizon Europe research programme, costing British scientists their place in pan-European research programmes.

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The last great mystery of the mind: meet the people who have unusual – or non-existent – inner voices

Does your internal monologue play out on a television, in an attic, as a bickering Italian couple – or is it entirely, blissfully silent?

Claudia*, a sailor from Lichfield in her late 30s, is not Italian. She has never been to Italy. She has no Italian family or friends. And she has no idea why a belligerent Italian couple have taken over her inner voice, duking it out in Claudia’s brain while she sits back and listens.

“I have no idea where this has come from,” says Claudia, apologetically. “It’s probably offensive to Italians.” The couple are like the family in the Dolmio pasta sauce adverts: flamboyant, portly, prone to waving their hands and shouting. If Claudia has a big decision to make in her life, the Italians take over.

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