I have a 50/50 chance of inheriting Huntington’s disease – should I take a test to find out? | Lillian Hanly

A coin toss could give me two completely different lives. But once I know the result there’s no going back

I’ve spent most of my life knowing I may have inherited a faulty gene that would cause Huntington’s disease, a neurodegenerative disease that can be fatal. My grandad had the disease, my mum has it, and I am yet to take the test to find out if I have it too. It’s a 50/50 chance of inheritance. Right now, I am happily ignorant of whether I carry the mutation or not. A coin toss could give me two completely different lives. Once I know the results, there’s no going back. So far, everyone who has been tested in my family has tested positive. It seems the odds are against me. I’m 27 years old, and I’m starting to think seriously about my future, whether that is moving overseas or contemplating having children. Whatever big decisions I am facing now, I can’t help but wonder, could this disease overshadow them? I explore this tension in a newly released short documentary, Fifty Percent.

Related: After the Nobel, what next for Crispr gene-editing therapies?

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Coronavirus live news: WHO expects 236,000 more Covid deaths in Europe by December; Philippines reports record high for new infections

Europe has registered around 1.3 million Covid deaths to date; Philippines sees 22,366 new cases; New Zealand’s largest city sees curbs extended by two weeks

With the return to school in the UK imminent, the Welsh education ministry said on Monday that all schools, universities and colleges in Wales would be supplied with ozone disinfecting machines.

Once a room has been disinfected, the machine, each the size of a suitcase, converts the ozone back to oxygen. But ozone is so toxic that no one will be allowed inside the room when the machine is operating.

It is like the use of chlorine, you don’t want to be in an environment where chlorine is dispersed at high concentration. Ozone smells but people are not allowed to smell it. That is extremely important from a safety point of view.”

Related: Concerns over plan to disinfect classrooms in Wales with ozone

Britain has reported 26,476 new cases of Covid-19 between 24 August and 30 August, 1.8% increase on the previous seven days.

A further 48 people were reported as having died within 28 days of a positive test for Covid-19, taking the seven-day increase to 14.8%.

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Covid booster jabs ‘not a luxury’ and protect the vulnerable, says WHO

Health body previously stated that boosters in Europe are unnecessary and will increase vaccine inequality

A booster jab of Covid-19 vaccine for vulnerable people is not a luxury but a good way to protect them, the World Health Organization has said, as surging infection rates and a pan-European vaccination slowdown produced a “deeply worrying” situation.

“A third dose of vaccine is not a luxury booster taken away from someone who is still waiting for a first jab,” Dr Hans Kluge, the WHO’s regional director for Europe, said on Monday. “It’s basically a way to keep the most vulnerable safe.”

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What personality are you? How the Myers-Briggs test took over the world

Deemed ‘astrology for businessmen’ for some, lauded as life-saving by others, the personality tests are a ‘springboard’ for people to think about who they are

I am a born executive. I am obsessed with efficiency and detached from my emotions. I share similarities with Margaret Thatcher and Harrison Ford. I am among 2% of the general population, and 1% of women.

People like us are highly motivated by personal growth, and occasionally ruthless in the pursuit. We make difficult partners and parents, but good landscape architects. We are ENTJs: extroverted, intuitive, thinking, judging – also known as the executive type or, sometimes, “the Commander”.

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Kidnapped, raped and wed against their will: Kyrgyz women’s fight against a brutal tradition

At least 12,000 women are still abducted and forced into marriage every year in Kyrgyzstan. But pressure is growing to finally end the medieval custom

Aisuluu was returning home after spending the afternoon with her aunt in the village of At-Bashy, not far from the Torugart crossing into China. “It was 5 o’clock in the afternoon on Saturday. I had a paper bag full of samsa [a dough dumpling stuffed with lamb, parsley and onion]. My aunt always prepared them on weekends,” she said.

“A car with four men inside comes in the opposite direction to mine. And all of a sudden it … turns around and, within a few seconds, comes up beside me. One of the guys in the back gets out, yanks me and pushes me inside the car. I drop all the samsa on the pavement. I scream, I squirm, I cry, but there is nothing I can do.”

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Being a Human review – two go mad in the stone age

Charles Foster’s search for the meaning of human life leads him and his son to become hedgehog-eating hunter-gatherers in a Derbyshire wood

Charles Foster’s previous book, Being a Beast, is one of the oddest things I’ve read. In it, the author, a barrister, professor of law, part-time judge and former vet, attempts to live as a series of animals, often in the company of his charming and heavily dyslexic eight-year-old son, Tom. We see Foster eating worms and burrowing into the earth as a badger, swimming naked as an otter, foraging in bins as a fox. Now Foster is back with a follow-up, Being a Human, which acknowledges the charges of eccentricity and even insanity that were levelled at the last book.

Foster’s new work continues the project of its predecessor, although this time, rather than seeking to understand the brains and bodies of animals, his question is closer to home: what does it mean to be human? He begins with a contentious argument: far from being a story of progress, the history of humanity is one of disenchantment and loss, one where we have severed our links with other species and the natural world more broadly and in which we live meagre, circumscribed lives. “Few of us have any idea what sort of creatures we are,” he says and embarks on a quest to find out.

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Passing the ‘chimp test’: how Neanderthals and women helped create language

How did humans learn to talk and why haven’t chimpanzees followed suit? Linguistics expert Sverker Johansson busts some chauvinist myths

How and when did human language evolve? Did a “grammar module” just pop into our ancestors’ brains one day thanks to a random change in our DNA? Or did language come from grooming, or tool use, or cooking meat with fire? These and other hypotheses exist, but there seems little way to rationally choose between them. It was all so very long ago, so any theory must be essentially speculation.

Or must it? This is the question presented as an elegant intellectual thriller by The Dawn of Language: Axes, Lies, Midwifery and How We Came to Talk. Its author is Sverker Johansson, a serene and amiable 60-year-old Swede who speaks to me over Zoom from his book-crammed home study in the city of Falun, where he works as a senior adviser at Dalarna University.

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An oral history of Oxford/AstraZeneca: ‘Making a vaccine in a year is like landing a human on the moon’

It has shipped more than a billion doses, saved countless lives – and faced controversy over its safety and supply. Here, some of those who created the vaccine tell the story of their epic race against the virus

In December 2019, hospitals in Wuhan, China, reported that they were dealing with dozens of cases of pneumonia of an unknown cause. They soon identified the disease as being caused by a novel coronavirus.

Teresa Lambe, associate professor, Jenner Institute My brother lived in China, so whenever there was an emerging or break pathogen there, I used to follow it. I remember thinking very early on that this was probably another influenza strain.

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NSW to lift ban on weddings; Victoria records 64 infections and ACT 26 – as it happened

Western Australia releases sites visited by Covid-positive NSW truck drivers. This blog is now closed

It’s time to wrap things up for another day. Here are today’s main events:

It has shipped more than a billion doses, saved countless lives – and faced controversy over its safety and supply.

In this piece by Oliver Franklin-Wallis, some of the people involved in the creation of the AstraZenca vaccine tell their story of the race against Covid-19.

Related: An oral history of Oxford/AstraZeneca: ‘Making a vaccine in a year is like landing a human on the moon’

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Delta variant doubles risk of hospitalisation, new study finds

Outbreak of Delta Covid cases likely to put strain on health services in areas with low vaccination rates, experts say

The Delta variant doubles the risk of Covid hospitalisation compared with the previously dominant Alpha variant, a new study focused largely on unvaccinated or partially vaccinated people has found.

The analysis – based on data collected in England – suggests that outbreaks of the Delta variant are likely to put an additional strain on health services, particularly in places with low rates of vaccination.

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Covid abnormal: why is Australia so far behind on making its own mRNA vaccines?

Annual coronavirus vaccines could be a reality – but Australia is at least 18 months away from manufacturing its own

From September – more than nine months after it was approved for emergency use in the United States – the first doses of the Moderna Covid-19 vaccine will arrive on Australian shores. The second mRNA (messenger ribonucleic acid) vaccine against the coronavirus is a welcome boon amid a period of rolling lockdowns and record case numbers.

But Australia’s notoriously sluggish vaccine rollout has been marred by the failure of a locally developed vaccine candidate, as well as changes to age-group recommendations for the AstraZeneca vaccine as a result of its link to rare but blood clots.

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Weight loss via exercise harder for obese people, data suggests

Research finds that when humans exercise, our bodies limit the energy used on basic metabolic functions

Losing weight through exercise appears to be more difficult for obese people, research suggests.

Initially, researchers thought that the total energy we spend in a day is the sum of energy expended due to activity (ranging from light gardening to running a marathon) and energy used for basic functioning (what keeps us ticking even when we are doing nothing, such as immune function and wound healing).

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Air pollution linked to more severe mental illness – study

Exclusive: research finds small rise in exposure to air pollution leads to higher risk of needing treatment

Exposure to air pollution is linked to an increased severity of mental illness, according to the most comprehensive study of its kind.

The research, involving 13,000 people in London, found that a relatively small increase in exposure to nitrogen dioxide led to a 32% increase in the risk of needing community-based treatment and an 18% increase in the risk of being admitted to hospital.

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Female hummingbirds look like males to avoid attacks, study suggests

Some females found to have evolved with bright plumage, which seems to protect against male aggression

They may zip around looking cute and sociable, but the world of hummingbirds is rife with aggression. Now it looks like some female hummingbirds have evolved to avoid this – by adopting the bright plumage of their male counterparts.

US researchers captured more than 400 white-necked Jacobin hummingbirds in Panama.

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Are Covid booster shots necessary? – video explainer

Many countries with already high vaccination rates are considering offering people an additional coronavirus vaccine dose. But are booster shots necessary? And what about the issue of vaccine equity? The Guardian's Natalie Grover examines the costs and benefits of possibly introducing a third jab

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LED streetlights decimating moth numbers in England

‘Eco-friendly’ lights found to be worse than sodium ones – but both contribute to insect decline, says study

“Eco-friendly” LED streetlights produce even worse light pollution for insects than the traditional sodium bulbs they are replacing, a study has found.

The abundance of moth caterpillars in hedgerows by rural roads in England was 52% lower under LED lights and 41% lower under sodium lights when compared with nearby unlit areas.

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Does Covid immunity wane and will vaccine booster jabs be needed?

Multiple studies seem to suggest immunity declines over time, though what this means is unclear

With plans for the UK’s Covid vaccine booster programme this autumn soon to be revealed, we take a look at what we do – and don’t – know about waning immunity after vaccination.

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Oxygen firms accused of intimidating Mexican hospitals during pandemic

Hospitals received letters threatening large fines after they installed their own onsite O2 plants in response to shortages

In March 2020, Benjamin Espinoza Zavala saw an entire floor of his small hospital in Guanajuato, central Mexico, converted into Covid-19 wards. The hospital’s need for oxygen soared.

Deliveries from CryoInfra, part of the Grupo Infra group, occasionally slowed to once every couple of days, and he had to buy in extra to cover the sudden gaps in supply. Prices increased.

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New Zealand won’t ‘throw in towel’ on Covid-zero strategy despite rising infections

Covid response minister says it would be a waste to stop aiming for elimination after plan was questioned by foreign media

New Zealand’s Covid response minister says the country will not “throw in the towel” with its elimination strategy, as cases continue to rise.

New Zealand announced 63 new cases of Covid-19 on Wednesday, bringing the total to 210 cases. It is the largest single-day jump since the outbreak began last week, and 12 people are hospitalised with the virus.

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