Scientists find ‘stealth’ version of Omicron not identifiable with PCR test

Researchers fear new Covid variant could spread unnoticed because rough means of flagging up cases does not work

Scientists have identified a “stealth” version of the Omicron variant which cannot be detected with the routine tests that public health officials are using to track its spread around the world.

The stealth variant has many mutations in common with standard Omicron, but it lacks a particular genetic change that allows lab-based PCR tests to be used as a rough and ready means of flagging up probable cases.

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As many as 6 million eligible Britons may not have had a Covid jab. Who are they?

The Omicron variant has refocused attention on vaccination rates as data shows disparities in uptake across age, region and ethnicity

Hundreds of cases of the new Omicron Covid-19 variant have now been confirmed in the UK and experts have called for a renewed focus on vaccination rates.

As of 4 December, just over eight in 10 people aged 12 or older UK-wide had received two doses of a coronavirus vaccine, according to data from the UK Health Security Agency, while 89% had received a first dose. This means about 6 million eligible people may still be unvaccinated, based on ONS population figures as opposed to counts of GP records. So who are they?

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Michele Brown was vaccinated – but had a suppressed immune system. Would better health advice have saved her?

The mother-of-two carefully shielded until the government said it was safe to see friends and family. She had no idea how her existing conditions could affect her

The feeling of relief was immense as 58-year-old Michele Brown returned home from the vaccine centre. Her husband, Terry, 61, had taken time off from his job as a supervisor at a heavy machinery factory to drive her to her second Covid-19 vaccination at a Gateshead community centre. In the car, Michele told her partner of 40 years that she felt like a weight had been lifted off her shoulders. “She said: ‘At least we’ve got that done,’” Terry remembers. “‘We’ll be OK.’”

It was 28 April 2021. Michele, who had rheumatoid arthritis, an underactive thyroid and diabetes, had spent the last year and a half shielding indoors, on government advice. She was careful. She had a Covid station set up on the breakfast counter: lateral flow tests, bottles of antibacterial gel and disposable face masks. When family came to visit, a mask-wearing Michele would banish them to the furthest corner of the living room. “We couldn’t kiss her,” remembers her daughter, Kim Brown, 41, who lives in Durham. “She would say: ‘You might have the coronies! I don’t want no coronies. You’re not giving me that crap.’”

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Australia live news update: NSW teachers’ strike closes nearly 400 public schools; Victoria pandemic bill becomes law

David Littleproud says ‘conversations are happening’ about Olympics boycott; NSW teachers’ strike closes nearly 400 public schools; three new Omicron cases detected in ACT, six Covid-19 infections overall; Victoria pandemic bill becomes law; ; Victoria records 1,185 cases and seven deaths; NSW records 260 cases and two deaths – follow all the day’s news

A suspected shark attack on Victoria’s Bellarine Peninsula has left two teens in hospital and shut a beach, reports Callum Godde from AAP.

Emergency services were called to Ocean Grove, south east of Geelong, just after 7pm on Monday.

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Covid live: early signs Omicron more transmissible, UK PM says; Scottish firms urged to let staff work from home

Early indications Omicron more transmissible than Delta, says Boris Johnson; Nicola Sturgeon says staff should work from home until mid-January

All international arrivals to the UK are now required to take a pre-departure Covid-19 test to tackle the new Omicron variant.

The tightened requirements have just come into force from 4am (GMT) on Tuesday 7 December.

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Viagra could be used to treat Alzheimer’s disease, study finds

US scientists say users of sildenafil – the generic name for Viagra – are 69% less likely to develop the form of dementia than non-users

Viagra could be a useful treatment against Alzheimer’s disease, according to a US study.

Alzheimer’s disease, the most common form of age-related dementia, affects hundreds of millions of people worldwide. Despite mounting numbers of cases, however, there is currently no effective treatment.

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Malaria kills 180,000 more people annually than previously thought, says WHO

UN agency says world must support urgent rollout of new vaccine as it reveals new figures for malaria deaths

The World Health Organization has called for a “massive, urgent” effort to get the new malaria vaccine into the arms of African children, as it warned that about 180,000 more people were dying annually from the disease than had previously been thought.

Dr Pedro Alonso, director of the WHO’s global malaria programme, said the RTS,S vaccine, recommended for widespread rollout in October, represented a historic opportunity to save tens of thousands of lives, mostly those of under-fives in sub-Saharan Africa.

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Coroners in England issue rare warnings over avoidable deaths in pandemic

Exclusive: at least 16 notices issued to prevent future deaths after inquests highlight care failures

Coroners in England have said lessons must be learned from failings made by overstretched services that struggled to adapt during the Covid pandemic, as details of inquests into deaths only now emerge.

At the height of the pandemic, everything from mental health and coastguard services to care homes had to quickly change how they operated, and coroners across England are highlighting failures made during this time through reports that identify avoidable deaths.

Azra Hussain, 41, who died in secure accommodation in Birmingham on 6 May 2020. Two months before her death, she had been due to begin electroconvulsive therapy, but because of an administrative error the treatment was cancelled and was then no longer possible because of Covid restrictions. The inquest jury concluded that had she been given this treatment, she would probably have lived.

Ruth Jones, a frail older woman thought to have caught Covid, who died in a care home after a fall in self-isolation. A coroner said the care home was not equipped to watch Jones during her isolation but she needed to be monitored because of her risk of injury if left alone.

Anthony Williamson, an experienced sea kayaker who died on his 54th birthday after getting into difficulty. The coroner said he was concerned there was a reduced level of coastguard cover around the Cornish coastline owing to the pandemic.

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Qld border to reopen 13 December, Palaszczuk says; SA premier advised to close border with NSW over Omicron – As it happened

Annastacia Palaszczuk brings forward Qld border reopening; Steven Marshall ‘very concerned’ by Omicron as SA records four Covid cases; Perth stripped of Ashes series finale; Victoria records 1,073 new cases and six deaths, NSW records 208 cases, ACT six; Katherine lockdown extended as NT records one case; Australia could be renewables ‘superpower’ but has wasted time, Chris Bowen says.

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A New South Wales government plan to control feral horses in Kosciuszko national park will allow horses to remain in the only known habitat of one of Australia’s most imperilled freshwater fishes and risks pushing the species closer to extinction.

Conservationists say allowing horses to continue to roam around some sections of the park will put vulnerable wildlife and ecosystems at risk.

There are lot of reasons even though they don’t get as sick as adults, they have a pretty strong role in spreading it back to family members and of course that can include parents and also, of greater concern, the grandparents. The older you are, the impacts of getting seriously ill or worse with Covid is greater.

The other reason is just so kids can do what kids are meant to do – go to school, play with their friends, do sport, do exercise, do social things.

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The case of the confident dog that developed PTSD | Gill Straker and Jacqui Winship

Helping Darling to relax has been vital – but unlike a human, she isn’t dealing with the ethical and cognitive issues often involved in post-traumatic stress

  • The modern mind is a column where experts discuss mental health issues they are seeing in their work

The word trauma has been so overused that it can sound meaningless.

Yet there are profound effects on the body and mind following exposure to traumatic events. Our capacity to cope becomes overwhelmed and we feel helpless as the limbic system, which is the part of the brain associated with fight flight and freeze, goes into overdrive.

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Scott Morrison repeats that Australians have ‘had a gutful of governments in their lives’; Peter Cundall dies at 94 – As it happened

Gardening legend Peter Cundall dies aged 94 as PM repeats that Australians have had a ‘gutful of governments in their lives’. This blog is now closed

Hunt is asked whether states, like Queensland, will hold off opening state borders until at least 80% of kids aged five to 11 are vaccinated given today’s announcement.

Hunt:

There is no reason for that. The Doherty modelling was set out very clearly on the 80% rates for double dosed across the country for 16 plus, and what we have seen now is that in terms of the 12 to 15-year-olds, we have now had an extra 1.8 million vaccinations over and above the Doherty modelling. The Doherty modelling was based on an 80% national rate for double dosed and didn’t include 12 to 15-year-olds.

A bit over a fifth of all cases of Covid are actually in the under 12s. Indeed, some of the early data with Omicron suggests it may actually be higher for the Omicron variant ... While most kids to get fairly mild infection and only a limited number end up in ICU, is great, there are bigger impacts.

Unfortunately about one in 3,000 of the kids who get Covid actually end up with this funny immunological condition called multi-system inflammatory condition. Those kids can end up being very sick for months. It is not the same as long Covid but it has some things in common, and it has a whole range of symptoms where the kid is just not well. That is one of the things we are protecting against by vaccinating children...

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‘Wall of secrecy’ in Pfizer contracts as company accused of profiteering

US company faces scrutiny over Covid profits after UK agrees to secrecy clause

Ministers have agreed a secrecy clause in any dispute with the drugs manufacturer Pfizer over Britain’s Covid vaccine supply. Large portions of the government’s contracts with the company over the supply of 189m vaccine doses have been redacted and any arbitration proceedings will be kept secret.

The revelation comes as Pfizer is accused by a former senior US health official of “war profiteering’’ during the pandemic. In a Channel 4 Dispatches investigation to be broadcast this week, Tom Frieden, who was director of the US Centers for Disease Control and Prevention under Barack Obama, said: “If you’re just focusing on maximising your profits and you’re a vaccine manufacturer … you are war profiteering.”

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UK’s progress on Covid now squandered, warns top scientist

Sir Jeremy Farrar, director of Wellcome Trust, suggests emergence of Omicron variant means pandemic is far from over

The emergence of the Omicron variant shows that the world is “closer to the start of the pandemic than the end”, one of Britain’s most senior scientific figures has warned, as he lamented a lack of political leadership over Covid.

Sir Jeremy Farrar, the director of the Wellcome Trust who stepped down as a government scientific adviser last month, said the progress in combatting Covid-19 since its emergence was “being squandered”.

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Omicron proves we’re not in control of Covid – only global action can stop this pandemic

If we keep allowing this virus to spread through unvaccinated populations, the next variant could be even more deadly

It’s almost two years since we first heard of Covid-19, and a year since the first Covid vaccines were rolled out. Yet this staggering progress is being squandered. We have drifted for months now, with richer countries, taking a very blinkered domestic focus, lulled into thinking that the worst of the pandemic was behind us. This variant reminds us all that we remain closer to the start of the pandemic than the end.

There is a lot we need to learn about the Omicron variant. Whether or not this is a pandemic-changing variant – one that really evades our vaccines and treatments – remains to be seen. Research will tell us more in the coming days and weeks, and we must watch and follow the data closely while giving the brilliant scientific teams time to get the answers. Although I am very worried about countries with limited access to vaccines, I am cautiously hopeful that our current vaccines will continue to protect us against severe sickness and death, if we are fully vaccinated.

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Are you dreaming of a booze-free Christmas? Join the (soda) club

The market in no- and low-alcohol drinks is booming in the UK as more people swap the festive hangover for mindful drinking

The concept of a Christmas without champagne, wine or whisky is counterintuitive to many. But this festive season, growing numbers of Britons are eschewing alcohol and gearing up for a teetotal – or at least partially so – celebration, according to retailers.

Sales in the no- and low-alcohol category, also known as “NoLo”, are expected to grow by 17% in the UK this year, reports IWSR Drinks Market Analysis, and will hit almost 19 million cases and a value of $741m (£558m). Meanwhile, Sainsbury’s, Waitrose and Tesco all report that sales of NoLo drinks have seen huge rises year on year, a trend they expect to continue in the run-up to Christmas, amid a rise in “mindful drinking”.

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‘I dread Christmas. My husband won’t get jabbed’: The families split over Covid vaccines as they plan holiday gatherings

We talk to three people faced with moral crises over reconciling family festivities with the risks posed by coronavirus

Christmas is meant to be a time filled with joy, but for many families it can underline divisions between parents, children or siblings and bring unresolved tensions to the surface. This year adds a particular issue to that dynamic – whether or not individual family members are vaccinated.

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I was told the 12 steps would cure my addiction. Why did I end up feeling more broken?

In this quasi-religious programme, ‘working the steps’ is the remedy for any problem, but for me the cracks soon started to show

Eight of us sat together in a circle in a wooden shed, an outbuilding at a large country house, somewhere in the south of England. The door was ajar, and spring light flooded the room. “Can anyone name any treatment methods for addiction, other than the 12 steps?” asked a counsellor.

Cognitive behavioural therapy?” offered a patient.

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Abuse, intimidation, death threats: the vicious backlash facing former vegans

Going vegan has never been more popular – but some people who try it and then decide to reintroduce animal products face shocking treatment

In 2015, Freya Robinson decided to go vegan. For more than a year, the 28-year-old from East Sussex did not consume a single animal product. Then, in 2016, on a family holiday in Bulgaria, she passed a steak restaurant and something inside her switched. “I walked in and ordered the biggest steak I could have and completely inhaled it,” she says. After finishing it, she ordered another.

For the previous year, Robinson had been suffering from various health problems – low energy levels, brain fog, painful periods and dull skin – which she now believes were the result of her diet. She says her decline was gradual and almost went unnoticed. “Because it’s not an instant depletion, you don’t suddenly feel bad the next day, it’s months down the line. It’s very, very slow.” In just over a year, the balanced plant-based food she cooked daily from scratch, using organic vegetables from the farm she works on, and legumes and nuts vital for protein, had, she felt, taken a toll on her body.

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WHO says no deaths reported from Omicron yet as Covid variant spreads

US and Australia become latest countries to confirm locally transmitted cases

The Omicron variant has been detected in at least 38 countries but no deaths have yet been reported, the World Health Organization has said, amid warnings that it could damage the global economic recovery.

The United States and Australia became the latest countries to confirm locally transmitted cases of the variant, as Omicron infections pushed South Africa’s total cases past 3 million.

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Labour MPs report Boris Johnson to police over 2020 Christmas parties

Met asked to investigate reports of alleged breaches of Covid lockdown rules at No 10

The prime minister has been reported to the police by Labour MPs over allegations there were at least two parties in Downing Street during lockdown restrictions last year.

Neil Coyle, Labour MP for Bermondsey and Old Southwark, wrote to the Met police commissioner, Cressida Dick, asking her to investigate reports that the prime minister spoke at a leaving do in November and also allowed a staff Christmas party to go ahead in December.

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