Delta variant doubles risk of hospitalisation, new study finds

Outbreak of Delta Covid cases likely to put strain on health services in areas with low vaccination rates, experts say

The Delta variant doubles the risk of Covid hospitalisation compared with the previously dominant Alpha variant, a new study focused largely on unvaccinated or partially vaccinated people has found.

The analysis – based on data collected in England – suggests that outbreaks of the Delta variant are likely to put an additional strain on health services, particularly in places with low rates of vaccination.

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Covid abnormal: why is Australia so far behind on making its own mRNA vaccines?

Annual coronavirus vaccines could be a reality – but Australia is at least 18 months away from manufacturing its own

From September – more than nine months after it was approved for emergency use in the United States – the first doses of the Moderna Covid-19 vaccine will arrive on Australian shores. The second mRNA (messenger ribonucleic acid) vaccine against the coronavirus is a welcome boon amid a period of rolling lockdowns and record case numbers.

But Australia’s notoriously sluggish vaccine rollout has been marred by the failure of a locally developed vaccine candidate, as well as changes to age-group recommendations for the AstraZeneca vaccine as a result of its link to rare but blood clots.

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Air pollution linked to more severe mental illness – study

Exclusive: research finds small rise in exposure to air pollution leads to higher risk of needing treatment

Exposure to air pollution is linked to an increased severity of mental illness, according to the most comprehensive study of its kind.

The research, involving 13,000 people in London, found that a relatively small increase in exposure to nitrogen dioxide led to a 32% increase in the risk of needing community-based treatment and an 18% increase in the risk of being admitted to hospital.

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Are Covid booster shots necessary? – video explainer

Many countries with already high vaccination rates are considering offering people an additional coronavirus vaccine dose. But are booster shots necessary? And what about the issue of vaccine equity? The Guardian's Natalie Grover examines the costs and benefits of possibly introducing a third jab

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All theories on origins of Covid-19 outbreak still ‘on the table’, says WHO

Remarks follow reports US intelligence study unable to conclude if virus came from animals or a Wuhan lab

The World Health Organization has said all theories on the origins of the Covid-19 outbreak, including the possibility of laboratory leak, are “on the table” and urged Chinese scientists to carry out their own investigations.

WHO officials were answering questions from the press after a classified US intelligence report delivered to the White House on Tuesday was reported to be inconclusive on the question of the origins of the pandemic, in part due to a lack of information from China.

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Does Covid immunity wane and will vaccine booster jabs be needed?

Multiple studies seem to suggest immunity declines over time, though what this means is unclear

With plans for the UK’s Covid vaccine booster programme this autumn soon to be revealed, we take a look at what we do – and don’t – know about waning immunity after vaccination.

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UK scientists look at reducing boosters to save vaccine for rest of the world

JCVI considers lower third jab dosage to release stocks for poorer nations

Scientists in Britain are examining whether smaller doses of Covid vaccine could be used as part of booster programmes, amid hopes that the approach could also increase the supply of jabs across the world.

The use of so-called “fractional doses” has been proposed as a way of ensuring that precious supplies can immunise as many people as possible in parts of the world where there are shortages, while still providing high levels of protection from the virus.

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The Wuhan lab leak theory is more about politics than science

Whatever this week’s Biden review finds, the cause of the pandemic lies in the destruction of animal habitats

If Joe Biden’s security staff are up to the mark, a new report on the origins of the Covid-19 pandemic will be placed on the president’s desk this week. His team was given 90 days in May to review the virus’s origins after several US scientists indicated they were no longer certain about the source of Sars-CoV-2.

It will be intriguing to learn how Biden’s team answers the critically important questions that still surround the origins of Sars-CoV-2, the virus that causes Covid-19. Did it emerge because of natural viral spillovers from bats to another animal and then into humans? Or did it leak from the Wuhan Institute of Virology? And, if so, had it been enhanced to make it especially virulent?

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Australia anti-lockdown rallies: protesters violently clash with police in Melbourne

Thousands march through streets of Melbourne and Brisbane, as police try to prevent Sydney rally

Anti-lockdown protesters clashed violently with police as thousands of unmasked people marched through the streets of Melbourne on Saturday.

Victoria police said they had made 218 arrests and that six officers were hospitalised during a series of altercations. Police said in a statement the majority of the estimated 4,000 demonstrators “came with violence in mind”.

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UK regulator approves ‘first of its kind’ Covid antibody treatment

Sajid Javid says green light for Ronapreve – which was used to treat Donald Trump – is ‘fantastic news’

The antibody cocktail used to treat Donald Trump for Covid has been approved by the UK’s medicines regulator, becoming the first treatment in Britain using artificial antibodies to tackle the virus.

The drug, developed by the US biotech company Regeneron, has received the backing of the Medicines and Healthcare products Regulatory Agency (MHRA). Clinical trials showed it helped to prevent Covid infection as well as to reduce the risk of hospitalisation or symptoms in severe cases, when given soon after exposure.

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Jabbed adults infected with Delta ‘can match virus levels of unvaccinated’

Researchers say implications for transmission remain unclear but reaching herd immunity even more challenging

Fully vaccinated adults can harbour virus levels as high as unvaccinated people if infected with the Delta variant, according to a sweeping analysis of UK data, which supports the idea that hitting the threshold for herd immunity is unlikely.

There is abundant evidence that Covid vaccines in the UK continue to offer significant protection against hospitalisations and death. But this new analysis shows that although being fully vaccinated means the risk of getting infected is lower, once infected by Delta a person can carry similar virus levels as unvaccinated people.

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WHO condemns rush by wealthy nations to give Covid vaccine booster

Move likened to handing out life jackets to those who already have them while letting others drown

The World Health Organization has condemned the rush by wealthy countries to provide Covid-19 vaccine booster shots, while millions of people around the world have yet to receive a single dose.

Speaking before US authorities announced all vaccinated Americans would soon be eligible to receive booster doses, WHO experts insisted there was not enough scientific evidence to support the additional shot.

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Covid news: all 16- and 17-year-olds in England to be offered first jab by 23 August – as it happened

UK department of health says the date will give teenagers change to build up immunity before school starts

We’re wrapping up the Covid live blog for today, here’s a quick summary of the latest developments:

France’s pass sanitaire health permit system will be extended to more than 120 major department stores and shopping centres on Monday in areas where levels of Covid infection are causing concern, including Paris and the Mediterranean coast.

The decision to extend the measure restricting entry to customers who can prove they have been vaccinated, have had a negative Covid test or have recovered from coronavirus was made by local officials.

The pass will now be required for shoppers entering Paris department stores such as Galeries Lafayette, Printemps, BHV, Le Mon Marché and La Samaritaine, and others mainly in the south of the country.

Related: French Covid permit scheme extended to Paris department stores

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New Covid variants ‘will set us back a year’, experts warn UK government

Vaccine-beating variant is ‘realistic possibility’, say scientists, amid calls for contingency plans to be revealed

Ministers are being pressed to reveal what contingency plans are in place to deal with a future Covid variant that evades current vaccines, amid warnings from scientific advisers that such an outcome could set the battle against the pandemic back a year or more.

Recent papers produced by the government’s Scientific Advisory Group for Emergencies (Sage) have suggested that the arrival of a variant that evades vaccines is a “realistic possibility”. Sage backed continued work on new vaccines that reduce infection and transmission more than current jabs, the creation of more vaccine-production facilities in the UK and lab-based studies to predict evolution of variants.

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‘No concept of how awful it was’: the forgotten world of pre-vaccine childhood in Australia

Until relatively recently, lethal infectious diseases stalked the lives of Australian children – including my father, Tom Keneally. Vaccines have saved millions

It’s 1940, and a five-year-old boy lies in an oxygen tent. He struggles for breath and hallucinates that his leaden toy soldiers are alive and marching around the room, monstering him with their bayonets.

He has diphtheria, a disease also known as The Strangling Angel. There is a vaccine, but not every child has been inoculated. The bacterial infection creates a membrane across the back of the throat, cutting off air supply.

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UK orders extra Covid vaccines for autumn 2022 booster campaign

Pfizer reportedly asked to supply 35m more doses, with final go-ahead for this year’s programme still awaited

Ministers have started ordering vaccines for a booster campaign in autumn 2022, with Pfizer reportedly being asked to supply the UK with a further 35m doses.

The government has still not give the final go-ahead for the vaccine booster programme expected this autumn, but it is understood to have placed the order with Pfizer despite the company raising its prices.

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Australia Covid live update: NSW on edge as cases spread in regions; Melbourne waits for news on lockdown

Melbourne faces the possibility of a lockdown extension as shopping centre workers ordered into quarantine; new cases emerge across regional NSW. Follow all the day’s news

Queensland LNP MP George Christensen has spoken to Sydney radio 2GB about being censured through a parliamentary motion yesterday.

The whole House, including the government, voted to support Labor’s motion disassociating the parliament with Christensen’s anti-lockdown and anti-public health measure comments yesterday (although Scott Morrison couldn’t bring himself to name or reference Christensen in his speech and just a hour or so later, cabinet minister Paul Fletcher declined five times on national TV to say he disagreed with Christensen’s views)

Happy Wednesday!

It’s not just hump day; we’re also halfway through the parliamentary sitting. At this stage, there’s a week break and then it’s back into it, but you have to wonder whether any of the east coast MPs will risk going home, given how quickly Covid is changing the landscape. Although, it doesn’t seem like anyone is missing the deputy prime minister, who has been in lockdown in Armidale, and apparently, unable to zoom in for the sitting (he has answered no questions in QT and offered no contributions to debate).

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Study links women’s middle-age height loss with greater risk of death

Research suggests those with higher loss are more likely to die early, even when exercise is taken into account

Women who experience greater height loss during middle age may be at higher risk of death, research suggests.

Scientists have previously found that shorter people may have an increased risk of heart disease, with researchers saying the two appear to be linked not just by lifestyle but by genes.

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Think it’s all over? Why the Covid experts are not so sure about that

Analysis: the end of restrictions in the UK has not led to a surge in cases, but coronavirus remains unpredictable

They are questions lurking in many people’s minds: just how upbeat or pessimistic should we be about the pandemic now? How does the UK compare with other countries? And is the worst of the crisis really over?

Two weeks after “freedom day” in England and with case numbers across the UK remaining lower than some modellers had feared, the worst seems to have eased. Future lockdowns, according to experts, seem unlikely unless new variants emerge.

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Prof Francois Balloux: ‘The pandemic has created a market for gloom and doom’

The UCL scientist and ‘militant corona centrist’ on the risk of new variants, psychosomatic long Covid and when he expects the crisis to end

Prof Francois Balloux is director of the University College London Genetics Institute. His work focuses on the reconstruction of disease outbreaks and epidemics. With his colleague Dr Lucy van Dorp, he led the first large-scale sequencing project of the Sars-CoV2 genome. During the pandemic, he has become a prominent scientist on Twitter, where he describes himself as a “militant corona centrist”.

Would you say a new variant of concern is still the major threat to our way out of this pandemic?
We haven’t had one in a while. The four variants of concern all emerged in the second half of 2020, and it’s important to keep in mind that viruses evolve all the time at a fairly regular pace.

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