Category Archives: Pharmaceuticals industry

Global report: leaders urge free vaccines as France allows staycations

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French drugmaker criticised for giving US priority; Gordon Brown says Covid-19 solution is global

More than 140 world leaders and experts have called for future Covid-19 vaccines to be made available to everyone free of charge, amid growing tensions between drug companies and governments and a boycott of vaccine summits by the US.

Vaccines and treatments for the virus should not be patented, say the signatories to an open letter published in the run-up to next week’s meeting of the World Health Assembly, the policy-setting body of the UN’s World Health Organization. Instead, scientific breakthroughs must be shared across borders, they urge.

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Covid-19 could mark a deadly turn in Ghana’s fight against fake drugs

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With substandard medicines already in wide circulation, fears are growing that coronavirus could create a lethal ‘parallel crisis’

When Joana Opoku-Darko’s daughter Anna was 18 months old, she came down with malaria, a disease common in Ghana and especially deadly for children.

She bought medication from a pharmacy in Ghana’s capital, Accra; when Anna’s fever didn’t subside she took her to a hospital, where they ran some tests.

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World’s stock markets soar on coronavirus treatment hopes

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Investors shrug off US growth gloom after promising data from remdesivir drug trial

Shares have soared on the world’s stock markets after investors shrugged off a deep slump in the US economy and pinned their hopes on a possible breakthrough in treatment for Covid-19.

Despite news that the longest expansion in US history came to an abrupt end in the first three months of 2020, financial markets were buoyed by an update from the American biopharma company Gilead Sciences on its experimental drug remdesivir.

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Paracetamol cannot treat coronavirus, NSW chief health officer says, only its symptoms – video

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New South Wales chief health officer Dr Kerry Chant addresses a misconception around paracetamol and the coronavirus crisis. With pharmacies and stores running low on supplies of the painkiller due to hoarding, Chant explained paracetamol only treats symptoms of Covid-19, not the virus itself

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Brexit threatens UK’s ability to respond to a future pandemic

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The coronavirus should remind us of just why international cooperation is so important in reducing the threat of infectious disease
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Brexit threatens the UK’s ability to respond to the novel coronavirus and future pandemics

The coronavirus pandemic could not have come at a worse time for the UK and its citizens. Just as UK government ministers are digging in for the really difficult part of Brexit, the negotiations on future relationships with the EU and the rest of the world, a new virus comes out of China that reminds us of just why international co-operation is so important.

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Revealed: Monsanto’s secret funding for weedkiller studies

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The research, used to help avoid a ban, claimed ‘severe impacts’ on farming if glyphosate was outlawed

Monsanto secretly funded academic studies indicating “very severe impacts” on farming and the environment if its controversial glyphosate weedkiller were banned, an investigation has found.

The research was used by the National Farmers’ Union and others to successfully lobby against a European ban in 2017. As a result of the revelations, the NFU has now amended its glyphosate information to declare the source of the research.

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Purdue payments to Sackler family surged after OxyContin fine

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Family started taking far more money out of firm after it was fined for misleading marketing of drug

The wealthy owners of OxyContin maker Purdue Pharma started taking far more money out of the company after it was fined for misleading marketing of the powerful prescription painkiller.

Purdue made payments for the benefit of members of the Sackler family totalling $10.7bn (£8bn) from 2008 through to 2017, a court filing made by the company on Monday evening shows.

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Zantac in global recall over ‘unacceptable’ levels of potential carcinogen

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Heartburn medicine pulled by GlaxoSmithKline while it investigates source of impurity

GlaxoSmithKline is recalling the popular heartburn medicine Zantac in all markets, days after the US Food and Drug Administration (FDA) found “unacceptable” levels of probable cancer-causing impurity in the drug.

Zantac, also sold generically as ranitidine, is the latest drug in which cancer-causing impurities have been found. Regulators have been recalling some blood pressure and heart failure medicines since last year.

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US attack on WHO ‘hindering morphine drive in poor countries’

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Claims have hurt efforts to help people around world in acute pain, say palliative care experts

An attack on the World Health Organization (WHO) by US politicians accusing it of being corrupted by drug companies is making it even more difficult to get morphine to millions of people dying in acute pain in poor countries, say experts in the field.

Representatives of the hospice and palliative care community said they were stunned by the Congress members’ report, which they said made false accusations and would affect people suffering in countries where almost no opioids were available.

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OxyContin maker Purdue Pharma files for bankruptcy

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Move is partly aimed at halting more than 2,000 lawsuits filed against drug firm

US drug-maker Purdue Pharma has filed for bankruptcy and announced a $10bn (£8bn) plan to settle thousands of lawsuits that accuse the company’s prescription painkiller, OxyContin, of fuelling the deadly opioids crisis.

The company, owned by the billionaire Sackler family, faces more than 2,000 lawsuits, including actions from nearly all US states and many local governments, which allege Purdue falsely promoted OxyContin by downplaying the risk of addiction. The public health crisis claimed the lives of nearly 400,000 people between 1999 and 2017, according to the latest US data.

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The science of senolytics: how a new pill could spell the end of ageing

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A simple treatment to stave off the health problems of old age could be available in five to 12 years. Here’s how it would work

The science of extending life is a subject of morbid fascination, conjuring the image of old billionaires being cryogenically frozen. But imagine if, instead of a pill you could take to live for ever, there was a pill that could push back the ageing process – a medicine that could stave off the fragility, osteoarthritis, memory loss, macular degeneration and cancers that plague old age.

It could happen, with the science of senolytics: an emerging – and highly anticipated – area of anti-ageing medicine. Many of the world’s top gerontologists have already demonstrated the possibilities in animals and are now beginning human clinical trials, with promising results. If the studies continue to be as successful as hoped, those who are currently middle-aged could become the first generation of oldies who are youthful for longer – with a little medical help.

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Opioids addiction rising in India as US drugmakers push painkillers

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As the Indian government loosens its prescription opioid laws after decades of lobbying by palliative care advocates, the cash-fed healthcare system is ripe for misuse

In the crowded waiting room of Dr Sunil Sagar’s clinic, in the working-class neighborhood of Bhagwanpur Khera, a toddler breathes from a nebulizer. The patients sit, motionless, but there is somehow tremendous noise. The clinic is a squat cement building draped in wires, a red cross on the door. Sagar sits behind a desk in a small, open room, as a squad of assistants escort patients to him.

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Johnson & Johnson responsible for fueling opioid crisis in Oklahoma, judge rules

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In landmark case, Oklahoma is first state to sue an opioid manufacturer all the way to trial as judge orders orders company to pay $572m

An Oklahoma judge has found Johnson & Johnson liable in a lawsuit claiming the giant drug maker helped fuel the deadly opioid epidemic in the state.

Oklahoma is the first state to sue an opioid manufacturer in court all the way to trial.

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Ebola now curable after trials of drugs in DRC, say scientists

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Congo results show good survival rates for patients treated quickly with antibodies

Ebola can no longer be called an incurable disease, scientists have said, after two of four drugs being trialled in the major outbreak in the Democratic Republic of the Congo were found to have significantly reduced the death rate.

ZMapp, used during the massive Ebola epidemic in Sierra Leone, Liberia and Guinea, has been dropped along with Remdesivir after two monoclonal antibodies, which block the virus, had substantially more effect, said the World Health Organization and the US National Institute of Allergy and Infectious Diseases, which was a co-sponsor of the trial.

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Canada announces regulations to cut price of prescription drugs

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  • Move hailed as ‘crucial step to lower prescription drug costs’
  • New rules were resisted by pharmaceutical companies

The Canadian government has announced regulations to reduce patented drug prices it said would save Canadians C$13.2bn (US$10bn) over a decade, overriding heavy opposition from pharmaceutical companies.

The changes are the biggest reform to Canada’s drug price regime since 1987. They will save money for patients, employers and insurers including the government at the expense of drug company profits. They also could eventually cut the earnings of drugmakers in the United States, the world’s largest pharmaceutical market.

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Capitalism gone wrong: how big pharma created America’s opioid carnage

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A web of firms ramped up narcotic painkiller sales, creating the biggest drug epidemic in American history as profits surged

As Oklahoma’s attorney general, Mike Hunter laid out his indictment against one of the biggest corporations in America, he made a point of saying that he was not hostile to big business.

“The fact that I am a Republican, a conservative and a believer in capitalism and the marketplace does not require me to turn a blind eye when corporations hurt people,” Hunter told a state court.

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Drug makers flooded US with billions of opioid pills as epidemic surged, data shows

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Statistics are a blow to country’s biggest pharmaceuticals that paid millions of dollars in out of court settlements

Drug makers and distributors flooded the US with more than 75bn opioid pills in the crucial years when the country’s epidemic of painkiller addiction and deaths surged to record levels, according to previously secret data released by an American court.

The publication of the Drug Enforcement Administration statistics is a blow to some of the country’s biggest pharmaceutical firms that have paid hundreds of millions of dollars in out of court settlements in part to keep sealed evidence that they profiteered from escalating demand for opioids even as public health officials were declaring an epidemic.

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‘There’s no opposition now’: how a quiet Canada town became a world leader in growing weed

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In an abandoned chocolate factory in Ontario, Canopy Growth is nurturing global ambitions. But could it thrive in Britain?

The musky aroma hits you from the car park at the headquarters of Canopy Growth, the world’s largest cannabis company.

Inside this nondescript warehouse – an abandoned Hershey’s chocolate factory in Smiths Falls, Canada – awaits the stuff of a stoner’s wildest dreams. Myriad rooms teem with row upon row of bushy marijuana plants at various stages of maturity, under intense lamplight, swaying in the breeze of dozens of fans.

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Vyleesi: latest attempt at ‘female Viagra’ approved by US regulators

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Pharmaceutical known chemically as bremelanotide is aimed at women with low sexual desire disorder or HSDD

Drug regulators in the United States have approved Vyleesi, the latest attempt to come up with a “female Viagra” for women with low sexual desire.

Vyleesi, chemically known as bremelanotide, is said to activate pathways in the brain involved in sexual desire, helping premenopausal women with hypoactive sexual desire disorder (HSDD). It has been developed by Palatin Technologies and licensed to Amag Pharmaceuticals, and is expected to be available from September through select pharmacies.

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Fight the fakes: how to beat the $200bn medicine counterfeiters | Helen Lock

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Armed with blockchain and AI, health workers and campaigners are battling the bogus business that kills thousands

By the time the teenage boy was standing in front of Bernice Bornmai, feverish and delirious, it was already too late.

It wasn’t just the malaria that was killing the 17-year-old, it was the time he’d wasted taking fake medicine. The antimalarials did nothing to stop the disease marching through the young Ghanaian’s body: his organs were already shutting down.

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