Category Archives: Pfizer

AstraZeneca overtakes Pfizer as crunch week for UK pharma looms

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Driven by a revamped drug portfolio, AstraZeneca is expected to report revenues of $10.7bn in its latest quarterly results

Nearly a decade after AstraZeneca fended off a hostile takeover approach from US rival Pfizer, the British drug firm has overtaken the Viagra maker in terms of market value, marking a significant moment in its turnaround – and for UK plc.

In a week when AstraZeneca and Britain’s second-biggest pharma firm GSK release their latest quarterly results and the main industry body, the Association of the British Pharmaceutical Industry holds its annual conference, all eyes will be on what pharma executives say about the UK as a place to operate and invest in.

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Biden will announce end of national and public health Covid emergencies in May

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The move to end the declarations comes as House Republicans are set to pass a resolution to demand their immediate scrapping

Joe Biden informed Congress on Monday that he will end the twin national emergencies for addressing Covid-19 on 11 May, as most of the world has returned closer to normalcy nearly three years after they were first declared.

The move to end the national emergency and public health emergency declarations would formally restructure the federal coronavirus response to treat the virus as an endemic threat to public health that can be managed through agencies’ normal authorities.

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US moves to simplify Covid vaccines into yearly dose to target variants

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The FDA asked its scientific advisers on Thursday to help chalk out plan to move to a flu shot-like schedule for coronavirus

The US is poised to make Covid-19 vaccinations more like a yearly flu shot, a major shift in strategy despite a long list of questions about how to best protect against a still rapidly mutating virus.

The Food and Drug Administration asked its scientific advisers on Thursday to help lay the groundwork for switching to once-a-year boosters for most Americans – and how and when to periodically update the shots’ recipe.

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Moderna sues Pfizer and BioNTech over coronavirus vaccine

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Company is suing pharmaceutical rival and its German partner for patent infringement

Moderna is suing its US pharmaceutical rival Pfizer and its German partner BioNTech for patent infringement in the development of the first Covid-19 vaccine approved in the United States, alleging they copied technology that Moderna developed years before the pandemic.

The lawsuit, which seeks undetermined monetary damages, was being filed in US district court in Massachusetts and the regional court of Düsseldorf in Germany, Moderna said in a news release on Friday.

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Pfizer vaccines that target Omicron variant pass first step to approval in Australia

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The TGA’s ‘provisional determination’ for two vaccines comes as BA.4 and BA.5 subvariants drive new wave of Covid cases

Two vaccines that specifically target the Omicron variant have been granted “provisional determination” by Australia’s drugs regulator, the first step in a process for getting the vaccines approved for use.

It comes as the BA.4 and BA.5 subvariants of Omicron drive a new wave of cases, prompting premiers to warn of increasing hospitalisations and deaths, and renewed calls to the public to wear masks in crowded indoor spaces.

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Pfizer to offer all its drugs not-for-profit to 45 lower-income countries

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Company launches ‘healthier world’ accord in Davos and speaks to other pharma firms about similar steps

Pfizer has announced it is to supply all its current and future patent-protected medicines and vaccines on a not-for-profit basis to 45 lower-income countries and is talking to other big drugmakers about similar steps.

Announcing an “accord for a healthier world” at the World Economic Forum (WEF) annual meeting in Davos, the New York-based pharma firm pledged to provide all its products that are available in the US and Europe on a cost basis to 1.2 billion people in all 27 low-income countries such as Afghanistan and Ethiopia, plus 18 lower-middle-income countries including Ghana.

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Pfizer seeks US authorization of Covid vaccine for children under five

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FDA decision could come within weeks but big obstacles remain to getting all children inoculated

Children under five, the last group of Americans still ineligible for vaccines against Covid-19, may soon receive emergency authorization for the shots, but getting all children vaccinated remains a serious challenge in the US.

Pfizer and its German pharmaceutical partner BioNTech announced on Tuesday that they were requesting emergency-use authorization of their vaccine for children aged six months to four years.

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‘We are so tired’: US parents and doctors say kids under five left behind in Covid vaccine race

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Child Covid cases have increased dramatically due to Omicron, yet no vaccine seems on the horizon for this age group

Four-year-old Joanna Gillikin likes to watch Ada Twist, Scientist, a Netflix children’s show about a young girl with a giant interest in science.

So when Matthew Gillikin and his wife, Shannon, enrolled Joanna in a trial in Charlottesville, Virginia, for the Pfizer vaccine against Covid-19, they described it to her as a science experiment, like the ones Ada does.

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Covid live: China locks down city of 5 million; enough vaccines for Canadians to get fourth dose, says Trudeau

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China locks down city of Anyang, bringing total under stay-at-home orders to 20m; Canada will give eligible people a fourth dose ‘if necessary’

Five million residents in the central Chinese city of Anyang have started home confinement today in a new lockdown to curb the spread of Omicron variant, according to state media and as reported by Agence France-Presse.

Two Omicron cases were detected in the city in Henan province, prompting authorities to announce a lockdown late Monday, issuing a notice ordering residents not to leave their homes or drive cars on the roads, state news agency Xinhua reported.

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Covid pills are ‘very promising’ – but what are the challenges in using them?

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Paxlovid and molnupiravir were authorized by the US FDA last week, but supplies of Paxlovid are limited while molnupiravir is less effective than hoped

An effective and widely available treatment for Covid would be a significant breakthrough for managing the pandemic, but two antivirals recently authorized in the US come with some significant caveats, including low supply and use only among those at high risk for severe illness and death.

Paxlovid from Pfizer and molnupiravir from Merck and Ridgeback Biotherapeutics were authorized by the US Food and Drug Administration (FDA) last week. The pills could be a game-changer for the most vulnerable, because they can be taken at home twice a day for five days to prevent hospitalization and death. For those considered at high risk of serious illness, Paxlovid was found to be 89% effective when taken within the first three days of symptoms and 88% effective in the first five days.

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Pfizer/BioNTech tax windfall brings Mainz an early Christmas present

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German city where early Covid vaccine was developed uses its new-found wealth to slash debt and attract other biotech firms

The Pfizer/BioNTech jab is having an unexpected side-effect on the German municipality where scientists first developed it: for the first time in three decades the city of Mainz expects to become debt-free thanks to the tax revenues generated by the company’s global success.

Mainz’s decision to use its financial windfall to also slash corporate tax rates in the hope of attracting industry, especially biotech companies, however, is drawing criticism from neighbouring cities and economists.

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More options for Covid treatments in January as FDA approves two antiviral pills

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The approval comes as reports of shortages in monoclonal antibody treatment arise and cases spike

People at greater risk of becoming seriously ill from Covid-19 will likely have more treatment options in January.

That’s the forecast in the wake of the US Food and Drug Administration’s approval this week of the first two antiviral pills used to treat Covid-19 and reports of shortages of a monoclonal antibody treatment used against the Omicron variant.

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Covid live: Israel extends travel ban over Omicron; German parliament debates healthcare vaccine mandate

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Ten day extension to restrictions announced as Israel detects 21 cases; lawmakers debate first of two German vaccine mandate laws

Fury over the release of a video showing Downing Street staffers joking about alleged lockdown breaches in the UK are only the latest scandal to rock British prime minister Boris Johnson’s premiership.

For days, a succession of government ministers batted away questions about whether an illegal party had been held in Downing Street last December during Covid restrictions that banned gatherings of more than 30 people. But on Tuesday night that all changed: a video emerged of Downing Street staffers appearing to joke about a party alleged to have been held inside No 10 just days earlier.

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Covid live: people in Scotland urged to cancel Christmas parties; UK reports another 50,867 cases and 148 deaths

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People and businesses in Scotland been urged not to go ahead with parties; UK daily case tally remains above 50,000

Cuba has detected its first case of the Omicron Covid variant, according to Cuban state media agency ACN.

The case was identified in a person who had travelled from Mozambique.

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Omicron spreads to 57 countries but too early to tell if variant more infectious, WHO says

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World Health Organization says new Covid variant spreading rapidly in South Africa, with cases doubling in the past week

The Omicron variant of Covid-19 has now been reported in 57 countries and continues to spread rapidly in South Africa, the World Health Organization (WHO) says.

But the latest epidemiological report from WHO says given the Delta variant remains dominant, particularly in Europe and the US, it is still too early to draw any conclusions about the global impact of Omicron.

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‘Wall of secrecy’ in Pfizer contracts as company accused of profiteering

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US company faces scrutiny over Covid profits after UK agrees to secrecy clause

Ministers have agreed a secrecy clause in any dispute with the drugs manufacturer Pfizer over Britain’s Covid vaccine supply. Large portions of the government’s contracts with the company over the supply of 189m vaccine doses have been redacted and any arbitration proceedings will be kept secret.

The revelation comes as Pfizer is accused by a former senior US health official of “war profiteering’’ during the pandemic. In a Channel 4 Dispatches investigation to be broadcast this week, Tom Frieden, who was director of the US Centers for Disease Control and Prevention under Barack Obama, said: “If you’re just focusing on maximising your profits and you’re a vaccine manufacturer … you are war profiteering.”

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UK Covid live: PM says people should not cancel Christmas events after highest cases since 17 July recorded

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Latest updates: Boris Johnson says ‘no need’ to cancel Christmas events as UK reports 53,945 daily coronavirus cases

Jeremy Corbyn posted a tweet this morning promoting a virtual Stop the War fundraiser this Christmas, not an in-person one. So my earlier post (now removed) about this being an example of a party going ahead that might not meet with George Freeman’s approval was completely wrong. I apologise for the mistake.

The Cabinet Office has been fined £500,000 for accidentally disclosing the postal addresses of the 2020 new year honours list recipients online, in breach of data protection laws.

On 27 December 2019 the Cabinet Office published a file on GOV.UK containing the names and unredacted addresses of more than 1,000 people announced in the new year honours list. People from a wide range of professions across the UK were affected, including individuals with a high public profile.

After becoming aware of the data breach, the Cabinet Office removed the weblink to the file. However, the file was still cached and accessible online to people who had the exact webpage address.

When data breaches happen, they have real-life consequences. In this case, more than 1,000 people were affected. At a time when they should have been celebrating and enjoying the announcement of their honour, they were faced with the distress of their personal details being exposed.

The Cabinet Office’s complacency and failure to mitigate the risk of a data breach meant that hundreds of people were potentially exposed to the risk of identity fraud and threats to their personal safety.

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South African scientists explore vaccines’ effectiveness against Omicron

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Crucial work will study how well current jabs work and whether they need to be updated to tackle new variant

Scientists in South Africa have begun crucial work to assess how well Covid vaccines hold up against the Omicron variant that has been detected in more than a dozen countries since it was formally reported last week.

The variant carries dozens of mutations that are expected to change how the virus behaves, including its ability to cause infection and how well it can hide from immune defences primed by vaccines or previous infection with an older variant.

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BioNTech says it could tweak Covid vaccine in 100 days if needed

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Company says it will know in two weeks whether current Pfizer jab is effective against Omicron variant

BioNTech says it could produce and ship an updated version of its vaccine within 100 days if the new Covid variant detected in southern Africa is found to evade existing immunity.

The German biotechnology company is already investigating whether the vaccine it developed with US drugmaker Pfizer works well against the variant, named Omicron, which has caused concern due to its high number of mutations and initial suggestions that it could be transmitting more quickly.

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Covid live news: fourth wave hitting Germany with ‘full force’, Merkel warns; Belgium mandates working from home

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Angela Merkel calls for an extra push on vaccinations; Belgium tightens restrictions as cases rise in fourth wave

Agence France-Presse is reporting that delivery and logistics firm FedEx have announced it is closing its operations base in Hong Kong over the city’s quarantine requirements.

“As the global business environment continues to evolve and with the pandemic requirements in Hong Kong, FedEx has made the decision to close its Hong Kong crew base and relocate its pilots,” FedEx said in a statement to Hong Kong’s public broadcaster RTHK.

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