Smart jab can shrink head and neck cancer tumours within six weeks, trial finds

Triple-action therapy drug amivantamab could be given as an injection to help treat recurrent or metastatic cancers

Doctors have hailed “incredibly encouraging” trial results that show a triple-action smart jab can shrink tumours in head and neck cancer patients within six weeks.

Head and neck cancer is the world’s sixth most common form of the disease. If it spreads or comes back after standard treatment, patients may be offered immunotherapy and platinum chemotherapy. But if this fails, there is often little else doctors can do.

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Ed Davey calls for UK to import US cancer researchers hit by Trump cuts

Lib Dem leader to use conference speech to urge extra funding for mRNA research and accuse Nigel Farage of cheering US funding reductions

The UK should import US scientists whose cancer research projects have been cut by Donald Trump, Ed Davey will argue at a Liberal Democrat conference that has focused heavily on how the party can respond to hard-right populism.

In his closing speech, Davey will also criticise Nigel Farage, saying the Reform UK conference applauded the Trump administration’s decision to slash funding for mRNA vaccines, which are being trialled as a way to offer personalised immunotherapy treatment for some cancers.

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Brain tumour diagnosis could be made within hours, say researchers

New testing method means treatments could start sooner, possibly before patient leaves the operating table

A new method for diagnosing brain tumours could cut the time patients wait for treatments by weeks to hours and raise the possibility of novel types of therapy, researchers have said.

According to the Brain Tumour Charity, about 740,000 people around the world are diagnosed with a brain tumour each year, around half of which are non-cancerous. Once a brain tumour is found, a sample is taken during surgery and cells are immediately studied under a microscope by pathologists, who can often identify the type of tumour. However, genetic testing helps to make or confirm the diagnosis.

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Top cancer experts ‘being put off UK by politicians’ messaging on immigration’

Exclusive: Leaked report says high visa costs also derailing clinical trials and research, denying NHS life-saving drugs

The world’s best cancer doctors, scientists and researchers are being put off moving to or staying in the UK by politicians’ rhetoric on immigration, a leaked report reveals.

Recruiting and retaining “global talent” to treat NHS patients and find new ways to cure cancer is vital, amid an acute British workforce crisis and rising numbers being diagnosed with the disease.

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NHS cancer patients denied life-saving drugs due to Brexit costs, report finds

Exclusive: Britons found to have ‘lost out’ while rest of Europe benefits from golden age of research and treatments

British cancer patients are being denied life-saving drugs and trials of revolutionary treatments are being derailed by the red tape and extra costs brought on by Brexit, a damning report warns.

Soaring numbers are being diagnosed with the disease amid a growing and ageing population, improved diagnosis initiatives and wider public awareness – making global collaborations to find new medicines essential.

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Prostate cancer surgery breakthrough offers hope for erectile function

Neurosafe procedure allows doctors to remove prostate while preserving as much nerve tissue around it as possible

A more precise form of prostate cancer surgery nearly doubles the chances of men retaining erectile function afterwards compared with standard surgery, according to the first comprehensive trial of the procedure.

Doctors in five UK hospitals assessed the surgical approach that aims to preserve crucial nerves that run through the outer layer of the prostate and are thought to be responsible for producing erections.

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Exposure to combination of pesticides increases childhood cancer risk – study

Study on cancer data in US agricultural heartland finds children more at risk than if exposed to just one pesticide

Exposure to multiple pesticides significantly increases the risk of childhood cancers compared to exposures to just one pesticide, first-of-its-kind research finds, raising new fears that children are more at risk to the substances’ harmful effects than previously thought.

The study’s authors say they are the first to look at the link between exposures to multiple widely used pesticides and the most common childhood cancers. Most research considers pesticides’ toxicity on an individual basis, and the substances are regulated as if exposures occur in isolation from one another.

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UK trial to assess if red grape chemical can prevent bowel cancer

Resveratrol, which is also found in blueberries and peanuts, has been found to slow tumour growth in mice

Red wine was once heralded as a boon for health that could protect the heart and even extend life expectancy. But while scientists have debunked this claim, they believe that at least one red wine ingredient – a compound called resveratrol – may hold genuine health benefits.

A trial launched this week will assess whether a low dose of the chemical, also found in red grapes, blueberries and peanuts, could help keep bowel cancer at bay. The study, one of the largest to date testing drugs for cancer prevention, will recruit patients who are at risk of the disease.

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Researchers study treatment for chronic pain in childhood cancer survivors

Team at Nottingham Trent University is investigating how chemotherapy in early life could damage nerve cells

Treatments that could help alleviate the chronic pain experienced by thousands of childhood cancer survivors are being investigated by scientists and researchers in the UK.

About eight out of 10 children survive their cancer for 10 years or more but more than half of them report delayed and ongoing pain in adulthood.

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Study of new personalised cancer therapies could ‘transform’ how the disease is treated

Large-scale clinical project could give real-time view of how well treatments are working and lead to earlier diagnoses

Scientists are embarking on a large-scale clinical study of new personalised cancer therapies which could give clinicians are real-time view of how well treatments are working.

The £9m partnership between the Francis Crick Institute, five NHS trusts, charities and bioscience companies will spend four years examining the effectiveness of new immunotherapy treatments and exploring new ways to detect cancer.

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Scientists develop glowing dye that sticks to cancer cells in breakthrough study

Experts say fluorescent dye, which spotlights tiny cancerous tissue invisible to naked eye, could reduce risk of cancer returning

Scientists have developed a glowing dye that sticks to cancer cells and gives surgeons a “second pair of eyes” to remove them in real time and permanently eradicate the disease. Experts say the breakthrough could reduce the risk of cancer coming back and prevent debilitating side-effects.

The fluorescent dye spotlights tiny cancerous tissue that cannot be seen by the naked eye, enabling surgeons to remove every last cancer cell while preserving healthy tissue. That could mean fewer life-changing side effects after surgery.

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Scientists make potential breast cancer breakthrough after preserving tissue in gel

Ability to preserve tissue in a special gel solution for at least a week will help doctors identify most effective drug treatments

Scientists say they have a made a potentially “gamechanging” breakthrough in breast cancer research after discovering how to preserve breast tissue outside the body for at least a week.

The study, which was funded by the Prevent Breast Cancer charity, found tissue could be preserved in a special gel solution, which will help scientists identify the most effective drug treatments for patients.

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Cancer signs could be spotted years before symptoms, says new research institute

Tests that can identify early changes in cells would give doctors more time to offer treatment, say Cambridge researchers

Scientists at a recently opened cancer institute at Cambridge University have begun work that is pinpointing changes in cells many years before they develop into tumours. The research should help design radically new ways to treat cancer, they say.

The Early Cancer Institute – which has just received £11m from an anonymous donor – is focused on finding ways to tackle tumours before they produce symptoms. The research will exploit recent discoveries which have shown that many people develop precancerous conditions that lie in abeyance for long periods.

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Cancer charities praise ‘brave’ Princess of Wales for speaking about her diagnosis

Cancer Research UK’s chief executive says high-profile cancer cases such as Catherine’s can help others to seek help early

Cancer charities have praised the Princess of Wales for her “brave” decision to speak out about her cancer diagnosis as a way to encourage others to get their symptoms checked.

In a video message released on Friday, Catherine, 42, spoke of how her condition was discovered after she underwent abdominal surgery in January. In the weeks that followed her procedure, wild rumours flew around her absence and silence – but she said she and her husband, Prince William, had needed time to explain the situation to their three children, George, 10, Charlotte, eight, and Louis, five.

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She beat a rare liver cancer – and now works with her father to find more cures

Cancer scientist decides to study the tumour that once afflicted his small daughter – and now her work is adding to his project’s success

Elana Simon was 10 years old when she started to experience severe pains in her abdomen. For two years, puzzled doctors put forward diagnoses including lactose intolerance, Crohn’s disease and stress. It was not until 2008 that they pinpointed the real cause. Elana was suffering from fibrolamellar carcinoma (FLC), a rare, usually lethal, form of liver cancer.

“In a way, it was comforting to have a word for what was wrong with me after so much confusion about my condition,” Elana told the Observer. “Pre-diagnosis, my life was a mixture of discomfort and fear. Now I had something to focus on.”

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Australia’s sun safety guidelines updated to take account of diverse skin types

New Australian guidelines balance the risk of getting too much sun exposure with the benefits of vitamin D

Growing evidence about the health importance of sun exposure and genetic differences in the population have prompted Australia to adopt new sun safety guidelines.

The research informing the update was published in the Australian and New Zealand Journal of Public Health on Tuesday, and led by Prof Rachel Neale from the QIMR Berghofer medical research institute in Brisbane.

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Oesophageal cancer test ‘should be made more available in UK’

Charities say deaths will be prevented if ‘sponge on a string’ test is widely adopted

A test that can detect oesophageal cancer at an earlier stage than current methods should be made more widely available to prevent deaths, charities have said.

The capsule sponge test, previously known as Cytosponge, involves a patient swallowing a dissolvable pill on a string. The pill then releases a sponge which collects cells from the oesophagus as it is retrieved.

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Thousands rally in solidarity on Invasion Day in Melbourne, Sydney; AFL clubs call for 26 January date change – as it happened

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Australian and Aboriginal flags raised during Canberra ceremony

Following the welcome to country, the flag-raising ceremony has begun, with six flags raised including two Australian flags, two Aboriginal flags and two Torres Strait Islander flags.

Australia is home to the oldest continuous culture on Earth, 65,000 years of uninterrupted heritage, demonstrated by the unique archeological evidence found in the very ground that you may are sitting on, found in the rocks and stones of this very place. That makes this continent unique in the whole world.

Ngunnawal’s view of heritage transcends time, it is our way of being with nature, best expressed in the Ngunnawal language through the concepts of respect and deep honour, coming together in the wellbeing for all.

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DNA test can detect 18 early stage cancers, scientists say

US biotech firm designs cheaper, less invasive multi-cancer screening test it says could be ‘gamechanger’

Scientists have developed a simple DNA test that can identify 18 early-stage cancers that experts say could represent a medical “gamechanger”.

Cancer accounts for one in every six deaths worldwide, but early detection can significantly improve outcomes. Existing screening tests have drawbacks, including invasiveness, cost and low levels of accuracy for early stage disease.

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AstraZeneca buys Chinese cancer therapy firm Gracell for $1.2bn

Gracell Biotechnologies acquisition marks China’s growing importance to the Anglo-Swedish drugmaker

AstraZeneca has struck a deal to buy a Chinese cancer therapy company for up to $1.2bn (£950m), as Britain’s biggest drugmaker expands its footprint in its second-largest market.

The Anglo-Swedish pharmaceutical firm announced on Tuesday it would acquire Gracell Biotechnologies, which is focused on a type of cancer therapy known as CAR-T that modifies a patient’s cells to fight the disease.

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