Cancer signs could be spotted years before symptoms, says new research institute

Tests that can identify early changes in cells would give doctors more time to offer treatment, say Cambridge researchers

Scientists at a recently opened cancer institute at Cambridge University have begun work that is pinpointing changes in cells many years before they develop into tumours. The research should help design radically new ways to treat cancer, they say.

The Early Cancer Institute – which has just received £11m from an anonymous donor – is focused on finding ways to tackle tumours before they produce symptoms. The research will exploit recent discoveries which have shown that many people develop precancerous conditions that lie in abeyance for long periods.

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UK needs more lab space if it wants to be science superpower, ministers told

Leading property firms also call for more tax breaks and improved transport links to hubs ahead of autumn statement

The UK needs to build more laboratory space, improve transport links and offer more tax breaks to achieve Rishi Sunak’s ambition of becoming a science superpower, two leading property firms have argued ahead of the autumn statement.

Demand for laboratories in the UK is growing fast, with lab vacancy rates of just 1% in Cambridge and London, and 7% in Oxford, according to a report by British Land, one of Britain’s biggest property developers, and the upmarket estate agency and advisory firm Savills.

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Death of baby after UK hospital missed vitamin jab ‘beyond cruel’, parents say

Addenbrooke’s hospital in Cambridge failed to give William Moris-Patto a routine vitamin K injection

The parents of a baby boy who died at seven weeks old after a hospital did not give him a routine injection have described the failure as “beyond cruel”.

William Moris-Patto was born in July 2020 at Addenbrooke’s hospital in Cambridge, where it was recorded in error that he had received a vitamin K injection – which is needed for blood clotting. The shot is routinely given to newborns to prevent a deficiency that can lead to bleeding.

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Police name woman and two children killed in fire in Cambridge

Gemma Germeney, 31, died at scene of flat fire in King’s Hedges, while Lilly and Oliver Peden, eight and four, died later in hospital

Police have named a woman and two young children who were killed in a fire in a flat in Cambridge.

Gemma Germeney, 31, died at the scene of the fire in Sackville Close, King’s Hedges, on Friday morning, according to Cambridgeshire police, while Lilly Peden, eight, and Oliver Peden, four, were taken to hospital where they later died.

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Fitzwilliam Museum in Cambridge explores founder’s slavery links

Historic and contemporary pieces interrogate city and university’s connections to colonialism

An exhibition by the Fitzwilliam Museum will explore Cambridge’s connections to enslavement and exploitation for the first time, both in the university and the city.

Black Atlantic: Power, People, Resistance features works made in west Africa, the Caribbean, South America and Europe, and interrogates the ways Atlantic enslavement and the Black Atlantic shaped the University of Cambridge’s collections.

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Warnings over NHS data privacy after ‘stalker’ doctor shares woman’s records

Exclusive: Victim speaks of feeling violated by hospital doctor incident that expert says is evidence of ‘systemic’ flaw in England

The confidentiality of NHS medical records has been thrown into doubt after a “stalker” hospital doctor accessed and shared highly sensitive information about a woman who had started dating her ex-boyfriend, despite not being involved in her care.

The victim was left in “fear, shock and horror” when she learned that the doctor had used her hospital’s medical records system to look at the woman’s GP records and read – and share – intimate details, known only to a few people, about her and her children.

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UK chip designer Arm chooses US-only listing in blow to Rishi Sunak

PM had held talks with firm’s owner SoftBank in effort to make London first choice for tech flotations

The Cambridge-based chip designer Arm is to pursue a US-only listing this year, dealing a major blow to Rishi Sunak’s ambitions to make London the first choice for tech company flotations.

The company, which is owned by the Japanese conglomerate SoftBank, confirmed its preferred plan of seeking a US-only main listing later this year, spurning the UK despite heavy lobbying by successive prime ministers.

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Town vs gown and car vs bike: row erupts over Cambridge congestion plan

Residents rally over scheme they believe will benefit only bicycling students and dons

In 1381, a mob sacked university buildings and burned books in the town square, shouting: “Away with the learning of clerks!” More recently, battle lines have been drawn over plans to build homes on green belt land and attempts to ban wild swimming in the river Cam.

Now, tensions between town and gown are rising again in Cambridge. This time, it’s over proposals to introduce a £5 congestion charge on weekday car journeys to the city, with a protest march to Parker’s Piece common planned for 27 November.

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Amazon to create more than 4,000 jobs in UK

US company says recruitment drive will take permanent workforce in Britain to 75,000

Amazon is creating more than 4,000 permanent jobs across the UK this year, the online company has announced.

The US firm said the recruitment drive would bring its permanent workforce in the UK to 75,000, having created 40,000 new jobs in the past three years.

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Loss of EU funding clips wings of vital crow study in Cambridge

Laboratory chief blames Brexit for closure as money for corvid brain power research dries up

One of Britain’s most important, and unusual, centres for studying cognition is facing imminent closure as a result of Brexit. Set up 22 years ago to study the minds of crows, rooks and other birds noted for their intelligence, the Cambridge Comparative Cognition Laboratory is set to cease operations in July.

Its director, Professor Nicola Clayton, told the Observer she was devastated by the prospect of ending her research there. Nor was she in any doubt about the prime reason for the centre’s closure.

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‘Follow the science’: AstraZeneca unveils £1bn R&D centre

Anglo-Swedish pharmaceutical company has come a long way since it fought off a takeover bid in 2014

Little expense has been spared at the giant glass and steel structure that sprouts from a once-vacant plot of land on the outskirts of Cambridge.

AstraZeneca’s £1bn new research and development centre houses 16 labs and 2,200 scientists, making it the biggest science lab in Britain along with the Francis Crick Institute in London, and the pharmaceutical company’s biggest single site investment to date.

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Sniffing out a bargain: how dog-friendly are Britain’s shops?

With more retailers welcoming pets, our reporter ventures out with her puppy Calisto to see if we really are a nation of animal lovers

It’s a Saturday morning and I’m crammed into a small changing room, attempting to try on a new pair of trousers. It’s always a struggle with the multiple layers of autumnal clothing, and I’m even more flustered than usual. Because also crammed into the tiny space is a large dog, giving me a quizzical look and clearly wondering if this is the start of a new game. She quickly decides, yes, yes it is.

Dog ownership is booming. According to the Pet Food Manufacturers’ Association, there are 12.5m dogs in the UK this year, with 33% of households having a canine companion, while the Kennel Club is among the charities and organisations that have reported a surge in puppy ownership during the Covid pandemic.

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Golden history of Kazakhstan’s Saka warrior people revealed

Exhibition at Fitzwilliam Museum in Cambridge to tell story of little known civilization that flourished from eighth to third century BC

Wisdom, as Bob Marley put it, is better than gold. From next month however, the precious metal is central to a major new historical exhibition in Cambridge using loaned artefacts telling the story of an ancient civilization little known beyond Kazakhstan.

Golden objects unearthed from ancient burial mounds built by the Saka warrior people of central Asia – a culture which flourished from around the eighth century BC to the third century BC – will go on display at the Fitzwilliam Museum.

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Giulio Regeni’s last messages before his death in Egypt counter spy claims

Facebook messages from the Italian student killed in Cairo in 2016 show his concerns about studying in the country

The Facebook messages written by the Cambridge student Giulio Regeni in the weeks leading up to his murder give the lie to any notion he was a spy or political agitator.

Even before he left England, Regeni was concerned about the risks he might face doing his thesis on trade unions in Egypt, a sensitive subject in the country.

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Friar crushed by cart: bone analysis hints at causes of medieval deaths

Research from three Cambridge grave sites suggests poor people were at greatest risk of injury

A friar crushed by a cart, another the victim of an attack by bandits: it sounds like the plot of a medieval mystery. But according to new research these are some of the possible misfortunes to have befallen those in centuries gone by.

An analysis of bones from 314 individuals aged 12 or older, dating from around 1100 to the 1530s, and found in three different sites across Cambridge, reveals that bone fractures were common among those buried in a parish cemetery – where many ordinary workers would have been laid to rest. But the team also found evidence of horrific injuries among those buried in an Augustinian friary, suggesting the clergy were not protected against violent events.

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‘Vigilantes’ on a mission to reunite owners with their stolen bikes

Britain’s cyclists take matters into their own hands as criminals cash in on post-lockdown popularity of cycling

It’s the buzz he gets from reuniting the cyclists of Cambridge with their stolen bikes that has turned Omar Terywall into a self-proclaimed “vigilante”. He said: “You get really hooked on it when you start seeing major progress – and, well, it’s just nice helping people really, isn’t it?”

Like others across the country, from Portsmouth to Glasgow, Terywall runs a local Facebook group where Cambridge cyclists share details of their stolen bikes in the hope they will be spotted. Well-regarded by local police, Terywall happily spends hours each day hunting down stolen bikes via online advertisements and local tip-offs.

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Elite Cambridge club asks members for £50,000 to keep it open

Pitt Club, founded in 1835, faces financial crisis after losing rental income from Pizza Express

It has survived a wartime recruitment crisis, a disastrous fire and a “horrible scarcity of whisky”. Now a Cambridge University members’ club is facing a surprising new challenge to its survival: the lockdown misfortunes of Pizza Express.

One hundred and eighty-five years after it was founded, the university’s Pitt Club – whose alumni include John Maynard Keynes, John Cleese and the Prince of Wales – is so close to financial catastrophe that it has been forced to make a desperate appeal to its lifetime members.

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Toppling Edward Colston’s statue is unlikely to be enough to stop public anger

Few imperial icons, including Churchill, will escape the need to reappraise Britain’s past

The toppling of slaver Edward Colston’s statue has electrified a longer term – and already deeply polarised – debate among British historians and academics, with some celebrating a “moment of history” as others warned of dark consequences for society.

Inaction over figures such as Colston had bred anger that would be felt “all over Britain”, said Andrea Livesey, a historian specialising in the study of slavery and its legacies and who described the events in Bristol as “wholly justified”.

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Sheikh’s daughter called UK police after kidnap, lawyer claims

Revelation fuels calls for investigations into Cambridgeshire force and Foreign Office after high court bombshell

There are demands for independent inquiries into the roles of the Foreign Office and Cambridgeshire police after an investigation into the abduction of a princess on a British street was allowed to lapse.

Princess Shamsa Al Maktoum of Dubai was snatched two decades ago by men working for her father, Sheikh Mohammed Al Maktoum, the billionaire ruler of Dubai, who is a friend of the Queen.

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