Venice is dry, and Italians are feeling something unfamiliar: hope| Gianmarco Raddi

The Mose flood-defence system’s success will boost a centre-left government enjoying a reputation for quiet competence

Venice’s flood sirens sing, piercing through the early morning fog. Metal bulkheads are in position, securing shops and grocery stores. Wooden walkways sneak through calli and salizade – our streets. Locals sport emergency rubber boots. These are routine acqua alta (high water) preparations. But on 3 October, for the first time in our city’s history, all of it was superfluous. The Adriatic waters that have been both curse and lifeblood to the city were held back. As Tommaso, a Venetian gondolier, exclaimed in dialect familiar to me from childhood (I grew up nearby): “Xe un miracoo!” – It is a miracle.

But far from being proof of divine providence, this modern parting of the waters is the work of Mose, or Experimental Electromechanical Module, an integrated system of coastal barriers and mobile dykes designed to protect the Venice lagoon from exceptional acque alte up to 3 metres above normal sea levels. It has been long in the making: construction – and controversy – started back in 2003, after decades of deliberations and tests following the destructive tide of 4 November 1966, to date the highest on record.

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Greater Manchester lockdown delay ‘could lead to overwhelmed hospitals’

Stretford and Urmston MP urges government to strike deal with local leaders over tier 3 financial aid

Downing Street must urgently strike a deal with Greater Manchester leaders to introduce tougher Covid restrictions before hospitals are overwhelmed, the shadow education secretary, Kate Green, has said.

Deputy mayors and other civic leaders in the metropolitan region said in a joint statement on Friday they were “ready to meet at any time” with the prime minister to agree a way forward over the introduction of a tier 3 lockdown. They say the government’s initial proposals did not provide adequate financial support.

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Covid reinfections ‘to be expected’ as virus spreads, say government scientists

Reports suggest timeframe between recovery and reinfection ‘relatively short’ for those who contracted virus twice

Government science advisers have warned that reinfections with Covid-19 are “to be expected” as the virus spreads, based on what is known about people’s immunity to other coronaviruses that cause the common cold.

Researchers on the Covid-19 Genomics UK Consortium said it was unclear at what point people who had recovered from the virus became vulnerable to reinfection, but cited emerging reports of second infections that suggested the timeframe was “relatively short”.

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Most US home health aides ‘can’t afford not to work’ – even without PPE

Home health caregivers have been key to the Covid response – but they often work for low wages and without overtime, hazard pay, sick leave or insurance

In March, Sue Williams-Ward took a new job, with a $1-an-hour raise.

The employer, a home healthcare agency called Together We Can, was paying a premium – $13 an hour – after it started losing aides when Covid-19 safety concerns mounted.

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US passes 8m coronavirus cases as death toll approaches 220,000

Trump claims virus will ‘peter out’ in country with most cases and highest death toll

The US passed 8m recorded coronavirus cases on Friday, another unwelcome mark for the country with the most cases and the worst death toll from the global pandemic, approaching 220,000.

Despite there being no sign that the pandemic is under control in the US, on Thursday Donald Trump said that the virus would “peter out”.

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Boris Johnson wrongly suggests new Covid rules will stop some parents seeing children – video

Responding to a question at a televised Downing Street press conference, the prime minister wrongly suggested that new coronavirus restrictions meant separated parents might not be able to see their children. This is not only incorrect, but has been so throughout Covid restrictions, with children allowed to move between the homes of separated parents even during the peak of lockdown in March

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Brexit: No 10 says ‘trade talks over’ and tells Barnier to cancel London trip unless he’ll compromise – live

PM says there will be no deal with EU unless there is ‘fundamental change’ in Brussels

From my colleagues Pamela Duncan and Niamh McIntyre

From tonight over half the population of England will be living in areas classed as “high risk” or “very high risk” under the government’s three-tier system, equivalent to 28.4m people.

All of Lancashire county (Lancashire, Blackburn with Darwen and Blackpool council areas) are to move from tier 2 to the higher tier 3 category from midnight, meaning more than 3m people are now living in the highest-risk areas.

Trade negotiations often involve threats to walk away, and dire forecasts, before both side agree to compromise, and Brexit-watchers have been waiting for the UK-EU trade talks to this moment. It came this morning, when Boris Johnson used a TV statement (see 12.29pm) to say that there would no deal without a “fundamental change” in the EU’s approach.

But threats only work if people take them seriously and Johnson’s comments do not seem to have been taken as a sincere statement of intent to talk away. It was telling that, despite being asked twice if he was saying the talks were over, he would not use those words. (See 12.41pm.) If the foreign exchange markets thought Johnson was abandoning hopes of a deal, the pound would have fallen (as it has repeatedly in key moments in the Brexit drama since 2016). But it didn’t. “Market participants see comments from Boris Johnson as mainly political posturing at this stage,” an analyst told Bloomberg.

The pound fluctuates between gains and losses after Boris Johnson says the nation is preparing for a thin, Australia-style trade deal with the EU https://t.co/lzBTCqlY8F pic.twitter.com/YbntZLyFca

There’s no point in trade talks if the EU doesn’t change its position. The EU effectively ended the trade talks yesterday.

Only if the EU fundamentally changes its position will it be worth talking.

What I would say to that is there is only any point in Michel Barnier coming to London next week if he’s prepared to discuss all of the issues on the basis of legal text in an accelerated way without the UK being required to make all of the moves, or if he’s willing to discuss practicalities of areas such as travel and haulage which the PM mentioned in his statement.

Our position is a clear one. Only if the EU fundamentally changes position will it be worthwhile talking.

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Trump v Biden at TV town halls: a president kept in check – latest reaction live

Joe Biden said at a town hall event Thursday night that he would announce before election day whether he favors expanding the supreme court.

Biden has repeatedly declined to lay out a stance on the issue amid an ongoing Republican sprint to install a third justice nominated by Donald Trump before the election, in what critics have called a naked power grab.

Related: Biden says he'll lay out stance on expanding supreme court before election

In a new interactive elections timeline, Alvin Chang has explained how various 2020 US election scenarios, including the case of Trump losing but refusing to concede, could play out.

Americans are used to a certain routine with presidential elections – but this year might be different, Alvin writes. If you’re not current on such concepts as the safe harbor deadline and wonder how states select electors, read about it here:

Related: Timeline: how 2020 US election scenarios could play out

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Wales facing ‘circuit breaker’ lockdown of two or three weeks

First minister says countrywide restrictions are top option being considered

Wales is facing a “circuit breaker” lockdown of two or three weeks to stop hospitals being overwhelmed, as the country reaches what the government described as a “critical point”.

Ministers will spend the weekend coming to a final decision on their next steps, but the Welsh first minister, Mark Drakeford, said on Friday a “fire-break” or circuit breaker for the whole country was the option most actively being considered.

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‘On the brink of disaster’: Europe’s Covid fight takes a turn for the worse

As France imposes curfews, even countries that previously managed well are struggling badly

“It’s not a word I’ve heard in a long, long time,” an elderly Paris resident said, leaving her apartment in mask and gloves for an early expedition to the shops. “A curfew. That’s for wartime, isn’t it? But in a way I suppose that’s what this is.”

Europe’s second coronavirus wave took a dramatic turn for the worse this week, forcing governments across the continent to make tough choices as more than a dozen countries reported their highest ever number of new infections.

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BAME people more likely to die from Covid than white people – study

ONS update also shows that males have higher death rate than females

People of black and South Asian ethnic background have a greater risk of death from Covid than white people, figures have confirmed, revealing such differences are not driven by pre-existing health conditions, but largely down to factors such as living arrangements and jobs.

Since the pandemic began, it has been clear that people of some ethnic backgrounds are at greater risk from the coronavirus than others, with previous data from the Office for National Statistics (ONS) suggesting black people have a four-fold higher risk of dying from Covid than white people.

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Remdesivir has very little effect on Covid-19 mortality, WHO finds

Results of major trial described as sobering, with drug found not to improve survival rates

Remdesivir, one of the big treatment hopes for Covid-19, has very little effect on preventing deaths, according to a large and comprehensive trial run by the World Health Organization.

The drug, made by the US biotech firm Gilead, has been talked up as a potential cure and was taken by Donald Trump. A trial in the US had previously showed it reduced the length of stay in hospital. But the gold-standard Solidarity WHO trial, which was based on a far larger sample – 3,000 people on the drug, compared with as many who were not – showed remdesivir had little effect on deaths over 28 days.

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Coronavirus: what has changed about what we know? – video explainer

Covid-19 has spread around the world, sending millions of people into lockdown as health services struggle to cope. From symptoms and long Covid to vaccines and treatments, the Guardian's health editor, Sarah Boseley, explains what we now know about the virus that we did not at the beginning of the crisis

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Coronavirus live news: Berlin court overturns government curfew on bars and restaurants; record Swiss cases

Berlin bar curfew suspended after court considers move ‘disproportionate’; Czech Republic records 9,721 new infections, Switzerland sees 3,105 cases

Bosnia’s new Covid-19 infections hit a record high for the third day in a row, with 621 cases on Friday, and authorities warned the healthcare system could collapse if the trend continues.

The country of around 3.3 million people has so far recorded 32,845 cases of the coronavirus with 980 deaths. Currently there are 7,262 active cases, or 1,512 more than a week ago.

“It’s not a word I’ve heard in a long, long time,” an elderly Paris resident said, leaving her apartment in mask and gloves for an early expedition to the shops. “A curfew. That’s for wartime, isn’t it? But in a way I suppose that’s what this is.”

Europe’s second wave took a dramatic turn for the worse this week, forcing governments across the continent to make tough choices as more than a dozen countries reported their highest ever number of new infections.

Related: 'On the brink of disaster': Europe's Covid fight takes a turn for the worse

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Queen and Prince William criticised for maskless visit

Palace says medical advice was sought before engagement at Porton Down defence lab

The Queen has carried out her first public engagement outside a royal residence since lockdown but there was criticism over her decision not to wear a mask.

She visited the Defence Science and Technology Laboratory (Dstl) at Porton Down near Salisbury with her grandson the Duke of Cambridge.

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Europe’s daily Covid deaths could reach five times April peak, says WHO

Hans Kluge says epidemic could worsen drastically, but latest controls could save lives

Daily coronavirus deaths in Europe could reach four or five times their April peak within months without effective countermeasures, the World Health Organization has said, as nine more countries reported record numbers of new infections.

Dr Hans Kluge, the WHO’s regional director for Europe, said on Thursday that Europe had recorded its highest weekly number of new Covid-19 cases as the virus again spread rapidly across the continent.

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French police search politicians’ homes in coronavirus inquiry

Health minister and former PM among those targeted after complaints over virus response

French police have searched the homes and offices of French officials including the former prime minister as part of an investigation into the government’s handling of the coronavirus crisis.

Current and former ministers have been targeted by at least 90 formal legal complaints from civic groups and members of the public over their response to the health emergency.

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Matt Hancock raises Covid alert level for parts of England including London – video

The health secretary told the Commons that several areas of England were being moved to the tier 2 level of coronavirus restrictions designed for high-risk areas. The new rules will come into force at one minute past midnight on Saturday, for an undetermined amount of time, in areas including London, Essex, York and north-east Derbyshire

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UK coronavirus live: London, Essex, York and north-east Derbyshire among areas put into tier 2 restrictions

Barrow-in-Furness, York, north-east Derbyshire, Erewash and Chesterfield move into tier 2 alongside London, Essex and Elmbridge; no decision yet on moving Greater Manchester and Lancashire into tier 3

In his response to Matt Hancock, Jonathan Ashworth, the shadow health secretary, asked why some contractors were being paid more than £6,000 a day to work on the much-criticised NHS Test and Trace. He said:

Today, new figures show just 62% of contacts reached, that’s the equivalent to 81,000 people not reached circulating in society - even though they’ve been exposed to the virus. This is another record low.

And yesterday we learnt that consultants working on test and trace are being paid over £6,000 a day to run this failing service. In a single week this government is paying these senior consultants more than they pay an experienced nurse in a year.

In the Commons the Manchester MP Lucy Powell said there were was “unanimous fury” from local MPs earlier when they were being briefed on the situation by one of Matt Hancock’s ministerial colleagues.

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13,300 new infections in Spain – as it happened

This blog is now closed. We’ve launched a new blog at the link below:

Hi, Helen Sullivan here. We’ve launched a new blog at the link below – head there for the latest:

Related: Coronavirus live news: France reports record new cases as WHO warns Europe's case surge is 'of great concern'

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