Shanghai’s full Covid lockdown ends after two months

City of 25 million people emerges from prolonged isolation under ruthlessly enforced restrictions

Shanghai has lifted a painful two-month lockdown, to the relief of the city’s 25 million residents, with authorities dismantling fences around housing compounds and ripping police tape off public squares and buildings.

Most residents have spent the past two months under a ruthlessly enforced lockdown that has caused income losses, stress and despair for millions struggling to access food or emergency healthcare.

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Medical research stalled as NHS focuses on small number of trials, experts say

Report outlines ‘research waste’ that occurred during the pandemic, with weakly designed trials exposing millions to unproven treatments

Government efforts to focus NHS resources on a smaller number of well-designed clinical trials could inadvertently be contributing to a backlog of stalled medical research, and result in some important trials being scrapped, researchers say.

Their warning comes as a report outlines the scale of “research waste” that has occurred during the pandemic, with rampant duplication of scientific efforts and weakly designed clinical trials exposing millions of patients to unproven treatments, with little scientific benefit.

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New Commons partygate inquiry poised to derail Tory conference

Privileges committee looks set to report in October, when Boris Johnson will be aiming to win back members’ trust

A House of Commons inquiry over whether Boris Johnson misled MPs over Partygate is on course to coincide with a Tory party conference already seen as crucial in resetting his leadership.

The prime minister appeared to have survived any immediate threat to his leadership in the wake of last week’s Sue Gray report on Downing Street parties, which revealed damning details of rule-breaking, drunkenness and abuse of No 10 staff during Covid lockdowns.

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Why are monkeypox cases suddenly emerging across the world and could the virus have mutated?

Data prior to current outbreaks suggested resurgence of the disease, with waning immunity from smallpox vaccination contributing to spread

The sudden emergence of monkeypox in several countries has raised questions about how the virus, which is most common in central and west Africa, has managed to spread.

Many health experts have said the monkeypox cases in 12 countries are not cause for panic, given the virus is much less infectious than illnesses like Covid and rarely fatal, but it is highly unusual.

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UN denounces ‘homophobic and racist’ reporting on monkeypox spread

Some media portrayals of cases among African and LGBTI people fueling blame, agency says, as infections reported in Europe, US and Australia

The United Nations’ Aids agency has called some reporting on the monkeypox virus racist and homophobic, warning of exacerbating stigma and undermining the response to the growing outbreak.

UNAIDS said “a significant proportion” of recent monkeypox cases have been identified among gay, bisexual and other men who have sex with men.

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More monkeypox cases detected in UK ‘on daily basis’, says scientist

Twenty cases confirmed in UK amid reports of child being admitted to intensive care in London hospital

More monkeypox cases are being detected in Britain “on a daily basis”, a senior doctor has warned, amid reports that a child has been admitted to intensive care with the disease.

Dr Susan Hopkins, a chief medical adviser to the UK Health Security Agency (UKHSA), said an update on confirmed cases would be released on Monday as efforts continue to contain the outbreak using contact tracing, testing and vaccination.

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WHO official warns monkeypox could accelerate as cases spread across Europe

The virus has been found in an ‘atypical’ spread in several countries as well as in the United States, Canada and Australia

A top European health official has warned that cases of the rare monkeypox virus could accelerate in the coming months, as the virus spread across Europe.

Hans Kluge, WHO regional director for Europe, said that “as we enter the summer season … with mass gatherings, festivals and parties, I am concerned that transmission could accelerate”.

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Two types of Omicron classified as Covid variants of concern in UK

Small number of BA.4 and BA.5 cases identified but data suggests ‘growth advantage’ over dominant BA.2

Two types of the Omicron variant of Covid-19 have been newly classified as variants of concern in the UK.

Only a small number of cases of Omicron BA.4 and BA.5 have been identified so far in the country, but analysis of the available data suggests they are likely to have a “growth advantage” over Omicron BA.2, currently the dominant variant, according to the UK Health Security Agency (UKHSA).

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Respiratory syncytial virus kills 100,000 under-fives every year

The acute lower respiratory infection has surged after Covid restrictions eased, experts say

Respiratory syncytial virus is killing 100,000 children under the age of five every year worldwide, new figures reveal as experts say the global easing of coronavirus restrictions is causing a surge in cases.

RSV is the most common cause of acute lower respiratory infection in young children. It spreads easily via coughing and sneezing. There is no vaccine or specific treatment.

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Mozambique confirms first wild poliovirus case in 30 years

Case in child in Tete province follows detection of similar strain in Malawi in February, officials say

Mozambique has identified its first case of wild polio in three decades following the genetic sequencing of a similar strain of the childhood disease in Malawi earlier this year.

Dr Matshidiso Moeti, the World Health Organization’s regional director for Africa, said the detection of the new case was “greatly concerning” and that it demonstrated “how dangerous this virus is and how quickly it can spread”.

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Surge in NSW flu cases sparks concern over hospital capacity with Covid numbers high

State’s chief health officer, Dr Kerry Chant, urges people to get flu vaccinations as 2,000 cases reported in last week

Surging cases of the flu are putting extra demand on emergency departments around New South Wales, with major outbreaks in boarding houses contributing to a doubling in cases in a week.

According to NSW Health, 2,000 flu cases were reported in the week to 7 May – up from 1,024 the week before.

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North Korea admits to Covid outbreak for first time and declares ‘severe national emergency’

Omicron infections create ‘biggest emergency incident in the country’, according to state media, as Kim Jong-un chairs response meeting

North Korea has declared a “severe national emergency” after confirming its first outbreak of Covid-19, prompting its leader, Kim Jong-un, to vow to quickly eliminate the virus.

State media reported on Thursday that a sub-variant of the highly transmissible Omicron virus, known as BA.2, had been detected in the capital, Pyongyang.

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‘No end in sight’: Shanghai residents chafe at harsh Covid measures

Tensions rise again as lockdowns grind on and the city’s population tire of strict zero-Covid policy

Tensions between Shanghai residents and China’s Covid enforcers are on the rise again, amid a new push to end infections outside quarantine zones to meet President Xi Jinping’s demand for achieving “dynamic zero-Covid”.

Videos shared on China’s social media platforms showed suspected Covid-positive patients forcibly quarantined in central facilities. In some neighbourhoods a single positive case could lead to residents in the entire apartment building be sent for quarantine.

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Beijing reopens mass isolation centre in fight against Covid

Chinese capital ramps up efforts to control Omicron outbreak and avoid lockdowns

Beijing has reopened a mass isolation centre as authorities seek to contain an outbreak of Covid-19 in the city.

The Xiaotangshan Fangcai hospital, which holds at least 1,200 beds and testing facilities, was first opened during the 2003 Sars epidemic, and used again in early 2020 to treat Covid patients. Its reopening signals a ramp up in efforts by China’s capital to manage the rising number of cases without going into a city-wide lockdown.

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Australian researchers uncover clue to rare and severe response to Covid in children

Breakthrough could improve diagnosis and lead to development of treatment for condition that has baffled doctors for two years

In the first months after Covid emerged, doctors were baffled by rare and severe responses to the virus in some children, whose symptoms included lung disease, blood clotting and heart damage.

Two years later and researchers led by the Murdoch Children’s Research Institute [MCRI] in Melbourne have uncovered the proteins involved in these acute inflammatory responses in children.

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Songs, tears and reunions: New Zealand welcomes back visitors as border reopens after two years

Vaccinated people from about 60 visa-waiver countries now able to enter as part of pandemic reopening plan

Māori songs, tearful embraces and a beloved New Zealand chocolate bar awaited international visitors arriving in New Zealand on Monday – the first foreign guests, other than Australians, to set foot in Aotearoa in more than two years.

Since March 2020, the arrival terminals at New Zealand’s international airports have been desolate as the country swiftly closed the border to prevent the arrival of Covid-19.

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Boris Johnson’s defence on Covid risk to care homes hit by new revelation

Prime minister had broached issue of asymptomatic transmission publicly with advisers long before testing rules were introduced

Boris Johnson’s claim that a lack of knowledge about the asymptomatic transmission of Covid-19 put care homes at risk has been further undermined after it emerged he openly discussed the potential scale of symptom-free transmission.

The prime minister has already been accused of misleading parliament over the claim. He made it last week after the high court ruled that the government had acted unlawfully in ordering the discharge of patients to care homes without testing in the spring of 2020. Johnson told the House of Commons: “What we didn’t know in particular was that Covid could be transmitted asymptomatically.”

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Number of UK children suffering from hepatitis rises to 145

Concerns rise about surge as scientists say lack of exposure to viruses during Covid restrictions could be factor

The number of children in the UK suffering from severe hepatitis has risen to 145 as concerns mount about the mysterious surge in cases.

The UK Health Security Agency (UKHSA) announced an increase of 34 cases but said most children have recovered and no children have died. There has been no increase from the 10 children who have required a liver transplant, reported on Monday.

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More than half of Americans have had Covid, including three of four children

A CDC report showed a striking increase in those with coronavirus antibodies between December and February

More than half of Americans show signs of a previous Covid-19 infection, including three out of every four children, according to a new report released on Tuesday.

The findings from the Centers for Disease Control and Prevention (CDC) come after researchers examined blood samples from more than 200,000 Americans and looked for virus-fighting antibodies made from infections, not vaccines. They found that signs of past infection rose dramatically between December and February, when the more contagious Omicron variant surged through the US.

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Only 29% of UK Covid hospital patients recover within a year

Of the 750,000 hospitalised, many still report fatigue, muscle pain, insomnia and breathlessness, with women worst affected

Fewer than one in three people who have been hospitalised with Covid-19 have fully recovered a year after they succumbed to infection.

That is the shock finding of a survey into the impact of long Covid in the UK. The team of scientists and doctors at Leicester University also found that women had poorer recovery rates than men after hospitalisation, while obesity was also likely to hinder a person’s prospects of health improvements.

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