Spain is first western European country to pass milestone; Rome among latest to bring in curfew; German health minister has Covid-19

• Spain is first western European country to pass 1m cases
• Lombardy cases more than double in a day
• 300,000 excess US deaths recorded as Cathay Pacific cuts 5,900 jobs
• New Zealand records 25 Covid cases amid arrival of foreign fishing crews
  

10.35pm BST

Four US states reported a record one-day increase in Covid-19 deaths on Wednesday including Wisconsin, a hotly contested state in the 3 November election, as infections keep rising across the Midwest and beyond.

Coronavirus deaths hit daily records in Iowa, Minnesota, Montana and Wisconsin, according to a Reuters analysis. Wisconsin also reported a record daily increase in new cases together with Illinois and Ohio, the analysis showed.

10.01pm BST

The US is likely to have enough safe and effective Covid-19 vaccines available to inoculate the most vulnerable Americans by the end of 2020, health and human services secretary Alex Azar said.

The US government is “cautiously optimistic” that one or two vaccines, likely from Pfizer or Moderna, will be available by the end of the year and can begin to be distributed to Americans, officials said during a news conference.

Johns Hopkins figures show new landmark tally; Italy introduces new restrictions; Dr Fauci not surprised that Trump caught coronavirus

• Global report: Fauci ‘absolutely not’ surprised Trump got Covid
• China becomes first major economy to recover from Covid-19 pandemic
• US coronavirus cases surge in most states
• See all our coronavirus coverage

10.45am BST

Malaysian health authorities reported 865 new coronavirus cases on Monday, raising the country’s total to 21,363. The Southeast Asian country, which imposed targeted lockdowns this month as infections surged, also recorded three new deaths, bringing its total number of fatalities to 190

10.19am BST

In the UK, the government is still facing resistance over its attempt to move Greater Manchester into a tier 3 lockdown.

The mayor, Andy Burnham, has said he is willing to resolve the impasse but won’t “just roll over” at the sight of a cheque.

Related: UK coronavirus live: Burnham says Greater Manchester resisting tier 3 as he won't 'roll over' for money

Berlin bar curfew suspended after court considers move ‘disproportionate’; Czech Republic records 9,721 new infections, Switzerland sees 3,105 cases

• ‘On the brink of disaster’: Europe’s Covid fight takes a turn for the worse
  
• Remdesivir has very little effect on Covid-19 mortality, WHO finds
• Fauci warns Americans to rethink Thanksgiving
  
• Italian critics aghast at comedy that makes light of pandemic
• UK coronavirus updates – live
  

3.19pm BST

Bosnia’s new Covid-19 infections hit a record high for the third day in a row, with 621 cases on Friday, and authorities warned the healthcare system could collapse if the trend continues.

The country of around 3.3 million people has so far recorded 32,845 cases of the coronavirus with 980 deaths. Currently there are 7,262 active cases, or 1,512 more than a week ago.

3.08pm BST

“It’s not a word I’ve heard in a long, long time,” an elderly Paris resident said, leaving her apartment in mask and gloves for an early expedition to the shops. “A curfew. That’s for wartime, isn’t it? But in a way I suppose that’s what this is.”

Europe’s second wave took a dramatic turn for the worse this week, forcing governments across the continent to make tough choices as more than a dozen countries reported their highest ever number of new infections.

Related: 'On the brink of disaster': Europe's Covid fight takes a turn for the worse