Northern Ireland and Wales to bring in tough Omicron restrictions

Devolved nations to reintroduce rule of six for hospitality venues and other measures from Boxing Day

Wales and Northern Ireland have announced stringent restrictions that will come into force from Boxing Day, including the return of the rule of six for hospitality venues, in an effort to curb the spread of the Omicron variant.

The first minister of Wales, Mark Drakeford, accused Boris Johnson of being in a “state of paralysis,” over Omicron as he set out a package of strict measures he said would put his country at “alert level two”.

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Data appears to support claims that Omicron is less severe in South Africa

Scientists warn, however, that lower severity of cases is not fully understood and may not occur elsewhere

South Africa has reported data on Covid cases driven by the Omicron variant that appears to give added impetus to claims the country is experiencing a lower severity of disease.

“In South Africa, this is the epidemiology: Omicron is behaving in a way that is less severe,” said Prof Cheryl Cohen of the country’s National Institute for Communicable Diseases (NICD), one of the authors of the study.

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Microplastics may be linked to inflammatory bowel disease, study finds

People with IBD have 50% more microplastics in their faeces but more research needed to confirm connection

People with inflammatory bowel disease have 50% more microplastics in their faeces, a study has revealed.

Previous research has shown that microplastics can cause intestinal inflammation and other gut problems in laboratory animals, but the research is the first to investigate potential effects on humans. The scientists found 42 microplastic pieces per gram in dried samples from people with IBD and 28 pieces in those from healthy people.

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Omicron is exploding – but scientists are better prepared than for any past variant | Manon Ragonnet-Cronin

We’re making progress in the arms race against the virus, but work in the lab must be supported by public health measures

It’s beginning to feel a lot like last Christmas. Case numbers of a new Covid variant are exploding across the UK, and the prime minister is cautioning that restrictions may be called for. But while the threat of Omicron likely surpasses that of previous variants, our tools to track and combat the virus have also advanced since last year.

The world was alerted to Omicron by the Botswanan and South African scientists who first sequenced the novel variant on 24 November, and it was designated as a variant of concern by the World Health Organization two days later. It was immediately obvious to them that they had something alarming on their hands when they saw the large number of mutations in the Omicron genome.

Dr Manon Ragonnet-Cronin is an MRC Fellow at Imperial College London and a member of the Imperial College Covid-19 response team

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Covid: how has the pandemic changed in the UK in 2021?

The year has been marked by the success of the vaccination drive – yet thousands have still died

This time last year, Covid-19 cases were soaring in the UK, hospitalisations were steadily increasing, and the government had tightened restrictions to try to get a handle on a concerning new variant.

Twelve months on, there is a sense of deja vu. A weary public is worried about its festive plans being cancelled, an outcome that would be all the more painful in light of the Christmas party scandal that has enveloped Downing Street in recent weeks.

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Covid live news update: Australia Covid live news update: national cabinet to meet as testing centres overwhelmed; NSW records 3,763 new cases, Victoria 1,503 cases

PM says mask guidelines up to states; NSW records 3,763 new cases and two deaths; Victoria records 1,503 cases and six deaths; ACT records 58 cases; Tasmania records 12 cases; national cabinet to meet as confidence in interstate travel plummets. Follow all the day’s news

More than 300 doctors around the world have written to deputy prime minister Barnaby Joyce today urging him to seek Julian Assange’s immediate release from prison in the UK on medical grounds.

The letter cites concern over Assange’s apparent mini stroke, warning it may be “the tip of a medical iceberg”:

Indeed his symptoms suggest as much. It is therefore imperative that Mr Assange be released from prison, where his health will otherwise continue to deteriorate and where his complex medical needs cannot be met.

Perhaps our concerns were previously dismissed by your colleagues as hyperbolic. They are not. On the issue of cardiovascular pathology, we have been proven right. We do not wish to be proven right on the issue of Mr Assange’s survival.

We implore you, as Deputy Prime Minister, to intervene with the UK Government to seek Mr Assange’s immediate release on urgent medical grounds. We reiterate that he is an Australian citizen innocent in the eyes of the law, and guilty of and charged with nothing in the UK.

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Australia Covid live update: AMA calls for mask mandate and density limits for Christmas; NSW reports record 3,057 cases, Victoria 1,245

AMA calls for mask mandate and density limits for Christmas; South Australia records 154 new Covid cases, Queensland 86; RACP calls on state and territory governments to reintroduce restrictions as PM says ‘we’re not going back to lockdowns’; Victoria records 1,245 cases; NSW records 3,057 cases; national cabinet to discuss vaccination timeframes and mask mandates – follow all the day’s news live

According to Seven News Scott Morrison is supportive of an indoor mask mandate in light of the Omicron variant spreading throughout Australia, but not further lockdowns.

Thousands of customers are still without power on Sydney’s northern beaches after the brief but cyclonic weekend storm that felled power lines, leaving a trail of destruction, reports AAP.

It’s a very difficult time of year to be without power, and we apologise for the delays. We are doing everything we can to turn the lights back on as soon as possible. Where we can, we are progressively turning power back on, and as always the safety of our customers and staff remains our number one priority.

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Israel announces fourth jab for over-60s; hospital bosses in England brace for ‘dangerous situation’

Portugal tells people to work from home from 26 December; Sweden announces working from home and tighter social distancing rules

Singapore has detected a cluster of three Covid-19 cases linked to a gym, its ministry of health said late on Monday.

The variant was found in two men, aged 24 and 21, and an 18-year-old woman.

On Monday morning, a mid-level staff member, who does not regularly have contact with the President, received a positive result for a Covid-19 test.

Three days earlier, on Friday, that staff member had spent approximately 30 minutes in proximity to the President on Air Force One, on the way from Orangeburg, South Carolina to Philadelphia, Pennsylvania.

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Global Covid vaccination failure will harm Britain, Gordon Brown warns

Exclusive: Ex-PM says virus will have ‘free rein to mutate’ unless richer countries fund $23bn vaccine drive

The failure to vaccinate the world against coronavirus will come back to haunt even fully vaccinated Britons in 2022, Gordon Brown has warned.

The former prime minister said the emergence of Omicron was “not Africa’s fault”, and added that new variants would continue to wreak havoc because richer countries such as the UK had “stockpiled” hundreds of millions of vaccines.

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Moderna says booster produces strong antibody response to Omicron

Pharmaceuticals firm says third dose of its Covid vaccine increases antibodies against variant by 37-fold

The pharmaceuticals company Moderna has said a booster dose of its Covid vaccine appeared to protect against the fast-spreading Omicron variant in laboratory testing and that the current version will continue to beits “first line of defence against Omicron”.

The decision to focus on the current vaccine, mRNA-1273, was driven in part by how quickly the variant is spreading. The company plans to develop a vaccine specifically to protect against Omicron, which it hopes to advance into clinical trials early next year.

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Contact with nature in cities reduces loneliness, study shows

Loneliness is significant mental health concern and can raise risk of death by 45%, say scientists

Contact with nature in cities significantly reduces feelings of loneliness, according to a team of scientists.

Loneliness is a major public health concern, their research shows, and can raise a person’s risk of death by 45% – more than air pollution, obesity or alcohol abuse.

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Christmas curbs could be brought in within days, says Sajid Javid

Health secretary expected to announce whether social mixing will be curtailed over festive period

Sajid Javid has made clear that fresh Covid restrictions could be imposed before Christmas to slow the spread of the Omicron variant, with ministers set to make a decision in days.

Government insiders expect an announcement to be made early next week about whether social mixing will be curtailed before the festive period – potentially including a cap on the number of families that can meet, or even hospitality closures.

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Life in the ward: how do you care for Covid patients in prison?

‘You can only build a net, it’s never a wall,’ says Dr Michael Novy, who cared for 160 inmates through a flap in a locked door

  • Read more in our series Inside Covid

From prisoners to the homeless and people living with disabilities – these are some of the at-risk communities hidden from public view during the pandemic. Now the health workers working with them share their stories.

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The science is clear: the case for more Covid restrictions is overwhelming

Analysis: Omicron studies so far have been rapid first takes, but the message for England is loud and clear

For a variant that came to light less than a month ago, the evidence for Omicron’s potential to wreak havoc has mounted at breakneck speed. What studies have emerged are rapid first takes, but the message they convey is now loud and clear: the scientific case for more restrictions is overwhelming. Without hard and swift action to curb transmission, the NHS faces a battering.

The first red flag came in late November when scientists in southern Africa shared early genomes of what became known as Omicron. Soon after they landed, Tom Peacock, a virologist at Imperial College London, highlighted the “awful” mutations that marked it out as a fast-spreading, vaccine-dodging variant. On receiving a text about Peacock’s tweet, Dr Susan Hopkins, the chief medical adviser to the UK Health Security Agency (UKHSA), conceded it filled her with gloom.

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London hospital staff speak out: ‘We’re not here to judge, but please get your Covid vaccines’

Health workers at King’s College hospital fear a surge in admissions as the Omicron wave gathers force, but are cautiously optimistic

On the third floor of one of the country’s biggest hospital trusts, a team of intensive care specialists in masks and visors huddle around a screened bay where a critically ill patient lies unconscious surrounded by cables and tubes.

The elderly man’s breathing is supported by a ventilator and he is connected to an arterial line to measure blood pressure. He is fed by a gastric tube, and a nearby stack of six monitors provide updates on his condition, from oxygen levels to heart rate.

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Is there any good news at all on Omicron? Yes, there are small signs of hope

Analysis: scientists are only starting to understand new Covid mutation but there is encouraging news from the laboratory, South Africa and on antiviral drugs

It’s hard to find much good news among the waves of grim statistics that have washed over the nation since the emergence of Omicron.

Once again, the NHS is threatened and again, the prospect of a new year lockdown looms. We seem to have gained nothing in the battle against Covid-19 during the past 12 months.

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It’s beginning to look a lot like last Christmas: why the UK has Covid deja vu

Omicron cases are soaring, experts want curbs and Boris Johnson is dithering. Sound familiar?

That old adage of Marx insists that historical events occur first as tragedy, then as farce. The government’s handling of the pandemic in the UK long ago undermined that progression: tragedy and farce have, since the very beginning of the crisis, always been a double act.

The clashing tone of current events feels like a dispiriting festive repeat of all-too-familiar dramas. A week that began with the exposed scandal of Downing Street lockdown parties, and ended with chief civil servant Simon Case stepping down as investigator of those scandals, because of a party in his own office, was also yet another week in which the alarming progress of the virus outpaced government rhetoric and claimed another thousand lives.

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‘A wave of joy’: babies born from world’s first HIV positive sperm bank

Sperm Positive launched in New Zealand in 2019 in an effort to reduce the stigma faced by HIV-positive people

Olivia and Amy are sitting outside in the shade, trying to escape from New Zealand’s early-summer humidity. Amy, 10 months old, burbles happily in the background as her mother talks. She is healthy, happy, and oblivious to her status as a world first: one of a handful of babies born from the first sperm bank for HIV-positive donors.

The bank, Sperm Positive, launched in New Zealand in 2019, in an effort to reduce the stigma faced by HIV-positive people – and raise awareness that with treatment, the virus was undetectable and untransmissible. It grabbed international headlines when it was launched, but has been more than a publicity gimmick. Two years on, the bank is bearing fruit.

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T-cells in Pfizer Covid jab recipients stay robust against severe illness

Research in South Africa raises hopes that similar responses may be present with other vaccines

South African researchers examining how the body’s immune system responds to the Omicron variant have identified that T-cells in people who have had the Pfizer vaccine continue to be robust in potentially protecting against severe illness despite Omicron’s ability to evade other defences.

The research raises hopes that similar responses may be present with other vaccines and within unvaccinated individuals who have been infected with coronavirus.

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Why a UK Omicron wave is dangerous – even if we see mostly mild cases

Analysis: If the spread continues at this rate, a small proportion of Covid hospitalisations is a serious matter

With the booster programme at full tilt across the UK, immunity against Covid is rising – so it is perhaps not surprising that the concern shown by experts over the steep rise in Omicron infections has left some bemused.

For while the new variant is believed to dodge Covid vaccines to some degree, it is thought the jabs still offer good protection against severe disease – particularly after a booster. And greater levels of immunity mean a lower ratio of hospitalisations to cases – something we have seen before in the UK, where about 22% of cases in those aged 65 and older ended up in hospital in early 2021, when Alpha was dominant but few had received a vaccine, compared with about 6% after the vaccine rollout was well under way.

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