Category Archives: Global health

‘A gamechanger’: new meningitis vaccine hailed as major step

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Successful trials in Africa of NmCV-5 vaccine open the door to affordable treatment for disease that kills 250,000 people a year

An effective, affordable meningitis vaccine has been successfully tested in Africa, raising hopes for the elimination of a disease that kills 250,000 people a year.

The NmCV-5 vaccine, developed by the Serum Institute of India and global health organisation Path, will protect against the five main meningococcal strains found in Africa, including the emerging X strain, for which there is currently no licensed injection.

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Injectable HIV-prevention drug to be made in South Africa for the first time

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Indian drug company to make cheaper generic version of CAB-LA, potentially protecting millions of people in Africa from the virus

An affordable version of a groundbreaking HIV-prevention drug will be made in South Africa for the first time, potentially giving millions of people at risk of HIV infection in Africa access to a two-monthly jab that can almost eliminate their chances of contracting the virus.

The Indian drug company Cipla confirmed that a generic version of the prophylaxis, long-acting cabotegravir (CAB-LA), would be manufactured at its plants in Benoni, near Johannesburg, or Durban.

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Pneumonia vaccine delays kill thousands needlessly in Africa

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Access to PCV jabs in South Sudan, Somalia, Guinea and Chad ‘could save 40,000 children a year’

Delays in rolling out a vaccine against childhood pneumonia in four of the world’s poorest countries have been blamed for thousands of unnecessary deaths.

South Sudan, Somalia, Guinea and Chad are four of the last African nations without the pneumococcal conjugate vaccine (PCV), one of the most powerful tools against pneumonia in children.

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Supplies running out at Sudan’s remaining hospitals as healthcare disaster looms

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In El Fasher, in North Darfur, only one hospital remains functional, with bomb damage, power cuts and only weeks until lifesaving equipment and drugs run out

Until gunfire broke out on the streets of El Fasher this month, the state capital of North Darfur had several main hospitals. There was the big teaching hospital, the Saudi hospital, a paediatric hospital and the South hospital, a modest 35-bed facility with big ambitions and a specific remit: to help bring down the high numbers of local women dying in pregnancy and childbirth.

Now, almost two weeks into the conflict between the Sudanese army and the paramilitary Rapid Support Forces (RSF), two weeks of bloodshed that has seen terror return to a region once synonymous with human suffering, those options have narrowed.

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Indian study reveals about 3% of drugs ‘substandard’ amid official crackdown

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In wake of children’s cough syrup scandal, an expert says regulatory system is ‘grossly understaffed and underfunctional’

About 3% of drugs routinely taken by Indians for ailments such as hypertension, bacterial infections and allergies are “substandard”, according to a study of samples taken from factories by government inspectors.

Officials have been carrying out random checks on factories after a scandal over Indian-made cough syrups linked to the deaths of children, mostly in countries in Africa.

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Ghana is first country to approve Oxford malaria vaccine

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Breakthrough hailed as highly effective R21 vaccine is cleared by west African country but questions remain over funding

Ghana has become the first country to approve a highly effective malaria vaccine developed at Oxford university in the UK.

The R21/Matrix-M vaccine, the first to exceed the World Health Organization’s target of 75% efficacy, has been cleared for use by Ghana’s Food and Drugs Authority in children aged 5-36 months, the group at highest risk of death from malaria.

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Victory over big pharma opens door to cheaper tuberculosis drugs

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India’s patent office turns down bedaquiline extension to Johnson & Johnson, clearing the way for generic versions

People with drug-resistant tuberculosis in India could soon have access to critical medication at a far lower cost after the authorities rejected US pharmaceutical giant Johnson & Johnson’s application to extend a patent.

The firm wanted to extend its patent on bedaquiline, which expires in July, until 2027, which would have prevented cheaper generic versions reaching the market.

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Virus outbreak in West Bengal leaves 19 children dead and thousands in hospital

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Indian state in crisis after adenovirus hits 12,000 people this year and families with sick children camp outside Kolkata hospital

Nineteen children have died of acute respiratory infections in West Bengal this year, and thousands more are in hospital as India grapples with an adenovirus outbreak.

More than 12,000 cases of adenovirus have been recorded in the state since January. More than 3,000 children have been admitted to hospital with severe flu-like symptoms.

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Children face acute risk amid Malawi’s deadliest cholera outbreak

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The disease, which has killed 1,500 people since last March, has been aggravated by heavy rains and an overburdened health system

Malawi’s cholera outbreak is the country’s deadliest on record, claiming more than 1,500 lives, according to the UN.

More than 50,000 cases have been detected in the landlocked country in south-east Africa since an outbreak was declared in March last year, triggered by two devastating tropical storms that hit the region. Almost 200 children have died.

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Guinea worm disease could be second ever human illness to be eradicated

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As cases fall, the condition that once affected millions of people in Africa and Asia could also be the first to be wiped out without medicines

The number of cases of a painful and debilitating tropical illness fell last year to a record low, fuelling hopes that it will soon become the second human disease in history to be eradicated.

Only 13 cases of guinea worm disease were reported worldwide in 2022, a provisional figure that if confirmed would be the smallest ever documented, the US-based Carter Center has said.

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Health workers in Zimbabwe dismayed as law curbing strikes is passed

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Controversial bill to stop industrial action criticised as an already struggling sector fears losing more staff in a damaging brain drain

Zimbabwe’s health workers have criticised the government for passing contested legislation that outlaws any industrial action, saying it will worsen the sector’s already damaging brain drain.

The new Health Services Bill, which came into force on Tuesday, forbids health workers who are classified as an “essential” service from striking for more than three days. Those who do not comply face a fine or imprisonment of up to six months.

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‘A great day for the country’: Uganda declares an end to Ebola outbreak

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Control measures including lockdowns have halted the spread of the virus after less than four months

The Ugandan government has declared an end to its Ebola outbreak, less than four months after cases were first reported.

Since 20 September, 56 people have died from the virus, which is spread through body fluids, and there have been 142 confirmed infections.

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Five million children worldwide die before fifth birthday, says UN

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Almost half of deaths occur in babies’ first month and most could be prevented with better healthcare according to campaigners

Five million children worldwide died before their fifth birthday in 2021, with almost half (47%) dying during their first month, according to new UN figures.

Most of the deaths could have been prevented with better healthcare, say campaigners, adding that deaths among newborn babies haven’t reduced significantly since 2017.

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Haiti receives its first batch of cholera vaccines to tackle deadly outbreak

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Campaign to stem the spread of the disease takes place against a backdrop of political chaos, gang violence and fuel shortages

Haiti has received its first shipment of cholera vaccines since an outbreak was declared more than two months ago.

The first of the 1.1m doses, delivered last week, will be distributed in the capital, Port-au-Prince, and surrounding areas in the hope of stemming the spread of the disease, which has been aided by political instability and lawlessness.

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‘Bring your own syringe’: Malawi’s medical supplies shortage at crisis point

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A lack of essential drugs and equipment is causing health centres to close, while critics accuse the government of complacency

Health workers in Malawi claim the government is “ignoring” acute shortages of drugs and equipment that are crippling the country’s hospitals.

Patients have been asked to bring in their own syringes while the theatre and labour ward at the main Bwaila maternity hospital in the capital, Lilongwe – has faced temporary closures because “we don’t have equipment/supplies to work with”, according to a notice pasted to a wall. Regular power cuts are also impacting.

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Sudan experiences worst dengue fever outbreak for more than a decade

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Floods caused by warming temperatures and a lack of preventive care are driving the spread of the disease in a country racked with political and economic upheaval

More than 1,400 people in Sudan have been diagnosed with dengue fever this year in the worst outbreak in the country for more than a decade.

Half of the country’s 18 states have registered cases and nine deaths recorded, including one child, according to the World Health Organization (WHO) who suspect the true number to be far higher.

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UN warns against alarmism as world’s population reaches 8bn milestone

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UNFPA head urges countries to focus on helping women, children and marginalised people most vulnerable to demographic change

The world must not engage in “population alarmism” as the number of people living on Earth nears 8 billion, a senior UN official has said.

The global population is projected to reach that milestone on 15 November, with some commentators expressing worries about the impact of the growing number on a world already struggling with huge inequality, the climate crisis, and conflict-fuelled displacement and migration.

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Dismay as key cholera vaccine is discontinued

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Exclusive: halt to production of Shanchol vaccine alarms WHO amid ‘unprecedented’ global outbreaks

The manufacturer of one of only two cholera vaccines for use in humanitarian emergencies is to halt production at the end of this year, just as the world faces an “unprecedented” series of deadly outbreaks, the Guardian has learned.

Shantha Biotechnics, a wholly owned Indian subsidiary of the French pharmaceutical company Sanofi, will stop production of its Shanchol vaccine within months and cease supply by the end of 2023, causing alarm among health officials.

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Health workers among dead in Ugandan Ebola outbreak

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MSF calls situation ‘very serious’ as east African country grapples with outbreak of Sudan strain of virus, for which no vaccine exists

It seems like a normal day in Mubende, central Uganda. Shops remain open, children are at school and public gatherings are allowed, provided people remain socially distant.

The ambulances that whisk past every few hours and the health workers who wash themselves meticulously before they return home are the only indications that it is not business as usual in the densely populated mining district, which is struggling to contain an outbreak of Ebola.

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UK under pressure to increase aid to Global Fund after US pledge

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Initiative to fight malaria, TB and Aids has asked for 30% increase after Covid crisis, but UK yet to announce pledge

Britain’s new government is facing the first test of its commitment to the global south as it decides whether to follow Joe Biden’s lead and pledge an extra £1.8bn to the Global Fund, the highly successful 20-year-old initiative that fights malaria, tuberculosis and Aids.

A replenishment event to cover funding for the next three years is taking place in New York, and Liz Truss’s administration has been delaying an announcement, partly owing to the death of the Queen.

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