Malaria trial shows ‘striking’ 70% reduction in severe illness in children

A study in Burkina Faso and Mali suggests combining anti-malarial drugs and vaccination could reduce deaths and hospitalisations

A trial combining vaccinations and prevention drugs has substantially lowered the number of children dying of malaria in two African countries, according to researchers.

The results of the study, published in the New England Journal of Medicine, have been hailed as “very striking”, especially at a time when decades-long progress on combating malaria has stalled in some countries.

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Are Covid booster shots necessary? – video explainer

Many countries with already high vaccination rates are considering offering people an additional coronavirus vaccine dose. But are booster shots necessary? And what about the issue of vaccine equity? The Guardian's Natalie Grover examines the costs and benefits of possibly introducing a third jab

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NHS planning Covid vaccines for children from age 12, reports say

UK health officials say no decision has been made yet as new school year in England looms

NHS England has been told to prepare to administer Covid vaccinations to all children aged 12 and above, as vaccine advisers continue to consider whether to extend the programme, according to reports.

The planned extension to the vaccination programme would coincide with the start of the new school year. NHS trusts have been told to have plans prepared by 4pm on Friday, the Daily Telegraph reported.

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The Guardian view on global vaccine inequality: unwise as well as unethical | Editorial

Richer countries must wake up and see the bigger Covid picture

The statistics are stark and shaming. During an exasperated intervention earlier this week, the World Health Organization’s director general, Tedros Adhanom Ghebreyesus, pointed out that of 4.8bn Covid vaccine doses delivered around the world to date, around 75% have gone to just 10 countries. The level of vaccine donations from richer countries, he added with some understatement, has been “really disappointing”. In Africa, where a third wave of the virus has been on the march since May, less than 2% of the continent’s population has received a first dose. While high-income countries across the globe have administered around 100 doses for every 100 citizens, the equivalent figure for low-income countries is 1.5.

As a consequence, while the United States, Britain and other richer nations begin to roll out programmes for booster shots in the autumn, a pandemic of the unvaccinated continues unabated elsewhere. The WHO’s target of reaching 10% of the population of every country with a first shot by the end of September is unlikely to be met. This grotesque inequity, as Mr Ghebreyesus and others have repeatedly pointed out, is ultimately in no one’s interest. Allowing much of the planet to operate as a variant factory, and the more transmissible Delta variant to run riot, stores up trouble for the future. “Vaccinating the world” should therefore be seen as sound strategy as well as an ethical obligation. But, in Europe and North America, early good intentions have so far come a distant second to domestic priorities.

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Does Covid immunity wane and will vaccine booster jabs be needed?

Multiple studies seem to suggest immunity declines over time, though what this means is unclear

With plans for the UK’s Covid vaccine booster programme this autumn soon to be revealed, we take a look at what we do – and don’t – know about waning immunity after vaccination.

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Taiwan hits zero Covid cases for first time since outbreak in May

Acceleration of vaccine rollout and test-and-trace improvements credited for turnaround

Taiwan has reported zero community cases of Covid-19 for the first time since its biggest outbreak began in May, killing more than 800 people.

“The local confirmed case today is zero, it was not easy,” the head of the Central Epidemic Command Centre, Chen Shih-chung, said on Wednesday.

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Fauci says US could be back to normal by spring 2022 – if vaccinations take off

‘It’s up to us,’ Fauci says as infectious Delta variant feeds surge in cases, with a majority of hospitalisations and deaths are among unvaccinated people

The US could have the Covid pandemic under control and achieve a return to “normality” by next spring, Dr Anthony Fauci said, if the “overwhelming majority” of the population is vaccinated.

Related: Biden hails announcement as FDA gives full approval to Pfizer’s Covid vaccine

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Does Covid-19 follow a similar seasonal pattern to flu?

Anticipating the seasonality of coronavirus is a key factor in fighting its spread, say scientists

It is well known that influenza is seasonal, peaking in the winter in temperate regions and during the wet season in tropical locations. So does Covid-19 follow a similar seasonal pattern?

To answer this question scientists compared coronavirus rates between March 2020 and March 2021 from five countries – Canada, Germany, India, Ethiopia and Chile – with daily mean temperature, humidity, ultraviolet radiation and air-drying capacity (a measure of how quickly droplets evaporate).

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‘Get it today’: Biden urges Americans to get Pfizer vaccine after FDA approval – video

President Biden urged Americans to come forward to receive the Pfizer vaccine after it received FDA approval. The US Food and Drug Administration (FDA) is trying to finish its licensing process for the drug as soon as Monday.

The president spoke directly to Americans who have said they would wait to get vaccinated until one of the vaccines received full FDA approval. 'It has now happened,' Biden said. 'The moment you’ve been waiting for is here. It’s time for you to go get your vaccination – and get it today'

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Anti-vaccine protesters occupy ITV and Channel 4 News headquarters – video

Anti-vaccine protesters occupied the headquarters of ITV News and Channel 4 News in London on Monday afternoon, in the latest of a series of actions aimed at the media.

After marching from King’s Cross station to ITN’s headquarters on Gray's Inn Road, protesters were met by two uniformed police officers guarding the building’s revolving doors. However, they were immediately let in through an emergency exit, apparently by a supporter who was already inside the building.

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Iranian government urged to accept western vaccines amid deadly Covid wave

Vaccine supplies close to exhausted in many areas as country gripped by fifth wave and daily death toll rises

The newly elected Iranian government led by President Ebrahim Raisi is facing demands to broaden its sources of vaccines as the country becomes engulfed by its fifth and most deadly wave of Covid-19.

The supply of vaccines is said to be close to exhausted in Isfahan and Tabriz, as well as provinces including Gilan, Khuzestan and Mazandaran.

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UK Covid deaths average 100 a day with fears of rise when schools return

Seven-day average now highest since March as children in Scotland return to the classroom

Deaths from Covid-19 are now averaging 100 a day across the UK, according to official data, and scientists have warned that case rates will jump again when millions of pupils return to schools next week.

The seven-day average for deaths within 28 days of a positive test now stands at 100, figures released by Public Health England on Monday show, a number that was last exceeded on 18 March.

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FDA gives full approval to Pfizer vaccine for Covid-19

Decision is likely to trigger a wave of formal vaccine requirements from government departments, businesses and schools

The US Food and Drug Administration (FDA) has given full approval to the Pfizer vaccine for Covid-19. The vaccine and others have been in use for months under emergency use authorisation.

Related: ‘You are not a horse’: FDA tells Americans stop taking dewormer for Covid

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Trump booed after telling supporters to get Covid vaccine

Former president held rally in Cullman, Alabama, a city struggling to cope with cases and hospitalisations

At his rally in Alabama on Saturday night, Donald Trump heard the unusual sound of booing and jeering aimed his way, after he told supporters: “I recommend taking the vaccines.”

Related: Tennessee radio host who criticised vaccine efforts dies of Covid-19

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Full FDA approval of Pfizer Covid shot will enable vaccine requirements

Full federal approval of Pfizer’s Covid-19 vaccine will empower businesses and universities to require vaccinations and tip hesitant Americans toward getting the jab, the surgeon general, Vivek Murthy, said on Sunday.

Related: Breakthrough infections and booster shots: what you need to know

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UK scientists look at reducing boosters to save vaccine for rest of the world

JCVI considers lower third jab dosage to release stocks for poorer nations

Scientists in Britain are examining whether smaller doses of Covid vaccine could be used as part of booster programmes, amid hopes that the approach could also increase the supply of jabs across the world.

The use of so-called “fractional doses” has been proposed as a way of ensuring that precious supplies can immunise as many people as possible in parts of the world where there are shortages, while still providing high levels of protection from the virus.

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Cuba’s health system buckles under strain of overwhelming Covid surge

A lack of medical supplies is crippling the Covid response, amid an economic crisis sparked by the pandemic and US sanctions

Julia, a community doctor in Havana, was drafted to the intensive care unit soon after Covid-19 first reached Cuba.

Last week, her cousin died from the virus. This week, she also tested positive amid a surge in cases which has pushed the island’s vaunted health service to its limits and prompted rare public criticism from Cuban doctors.

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Springsteen and LL Cool J to play New York comeback concert – as Covid surges

Thousands will show proof of vaccination to attend star-studded Central Park extravaganza as city averages nearly 1,900 cases a day

As coronavirus cases continued to rise across the US, thousands were expected nonetheless to attend a concert in Central Park on Saturday night, staged to celebrate New York City’s recovery amid the pandemic.

Bruce Springsteen, Paul Simon, Jennifer Hudson, Carlos Santana, LL Cool J and Andrea Bocelli were included in the lineup for We Love NYC: The Homecoming Concert. Most tickets distributed by the city were free, with attendees required to show proof of vaccination.

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Breakthrough infections and booster shots: what you need to know

Vaccine efficacy against infection is waning slightly with time – but efficacy against severe symptoms remains strong

Federal health authorities have recommended booster shots for all adults who are fully vaccinated against Covid-19 with either the the Pfizer or Moderna vaccines, citing evidence that suggests breakthrough infections could become more common over time.

The plan has faced scrutiny. Some US scientists have said data was insufficient to support the decision, and vaccines remain highly effective against severe disease requiring hospitalization and death. The World Health Organization harshly criticized US leaders for using vaccines to provide a third shot to people, even as most around the world haven’t had one.

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Covid Australia live news update: greater Sydney lockdown extended until end of September; NSW announces 642 cases, four deaths; Victoria records 55 cases

ACT chief minister Andrew Barr calls on colleagues to stop presenting 70% or 80% vaccination targets as ‘freedom day’ ahead of meeting. Follow latest updates

Berejiklian:

I also want to stress that from Monday midnight, unless you’re exercising masks should be worn outdoors everywhere across New South Wales.

Our concern is that when people are walking past a group of people or accidentally bumping into people that, that can cause that fleeting contact can cause transmission, and even when you’re exercising, you need to have the mask unless you’re doing some strenuous exercise.

Berejiklian:

So from Monday at midnight, the greater Sydney lockdown will extend until the end of September... but I also want to state that the Central Coast and Shell Harbour will be defined as regional.

So Greater Sydney includes all those areas that are currently in lockdown in Greater Sydney but for the Central Coast and Shellharbour which will be defined as rural and regional as we announced yesterday.

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