Global report: AstraZeneca chief believes Covid vaccine will work on variant strain

Pascal Soirot says firm has ‘winning formula’ to improve Oxford jab’s efficacy, as countries across Europe roll out vaccination programs

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The head of the firm behind the Oxford Covid vaccine has said researchers believe the jab will be effective against the variant strain of the virus that was first found in the UK.

AstraZeneca chief executive, Pascal Soriot, told the Sunday Times more tests were needed to be sure, but hailed the discovery of what he called a “winning formula” to improve the vaccine’s efficacy.

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Ten reasons why we got Covid-19 vaccines so quickly without ‘cutting corners’ | Adam Finn

The speedy rollout is thanks to a combination of foresight, hard work and lucky breaks

The speed at which effective Covid-19 vaccines have come through to authorisation has caused surprise. Compared with previous vaccines, the process has been very fast and so, naturally, people are asking how can it have happened without some kind of compromise on standards and care. Explaining it all as simply a result of the wonders of the latest scientific advances seems vague. So how has it actually come about? In reality, there are at least 10 reasons: some are about good planning, some good science and some just good luck.

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More data needed before giving just one vaccine dose, says Covid adviser

Tony Blair and others make argument for giving more people a single jab rather than two

A senior scientific adviser has said more data is needed before the government can adopt a proposal to give as many people as possible a single dose of a Covid vaccine rather than preserving stocks so there is enough for a second jab.

The former prime minister Tony Blair and Prof David Salisbury, a former director of immunisation at the Department of Health, backed the idea on Wednesday, saying second shots should be given only when more stock is available.

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NHS leaders raise concerns over pace of Covid vaccine rollout

Exclusive: more than half of hospital trusts in England yet to receive supplies as variant spreads

NHS leaders have raised concerns about the rollout of the coronavirus vaccine, with more than half of hospital trusts and two-thirds of GPs yet to receive supplies amid growing alarm over the new fast-spreading variant.

Dr Richard Vautrey, the chair of the British Medical Association’s GP committee, urged the government to speed up delivery of the Pfizer/BioNTech vaccine in order to save lives. Experts also demanded greater transparency from ministers on how many doses are available.

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Dr Fauci feels ‘extreme confidence’ in Covid vaccine as he gets jab – video

Dr Anthony Fauci was injected with his first dose of the Moderna Covid-19 vaccine and he said he hoped it would encourage millions of other Americans to do the same.

The top US infectious diseases expert said he felt 'extreme confidence of the safety and efficacy of this vaccine'

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Inside Oxford’s coronavirus vaccine development

From a small discovery to producing at scale, photojournalist David Levene documents the groundbreaking work of the scientists of Oxford University during the development of a vaccine which is now poised for approval by medicines regulators

From the moment the coronavirus spilled out of China and spread around the world, the great hope for the return of normal life lay with safe and effective vaccines. While wearing masks and washing hands helped to reduce the flood of infections, they would never be enough to hold back the tide. Social distancing – a phrase that does nothing to convey the hardship of the act – suppresses the virus, no doubt. But what kind of life is a life lived apart?

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Moderna vaccine shipments begin as US reels under Covid surge

Workers began processing shipments of the second US Covid-19 vaccine on Sunday, but across the country the situation remained severe.

Related: Two authorized vaccines – here's what you need to know.

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Belgian minister tweets EU’s Covid vaccine price list to anger of manufacturers

Pharmaceutical companies complain of breach of confidentiality after amount EU has agreed to pay for leading vaccines goes public

A Belgian minister has blown the lid off a sensitive and commercial secret – the price that the EU has agreed to pay for the leading Covid vaccines.

Belgium’s budget state secretary, Eva De Bleeker, posted the price list on Twitter, with the amounts of each vaccine that her country intends to buy from the EU. The tweet was quickly deleted, but not soon enough to prevent interested parties taking screenshots, which have now made it public knowledge.

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‘Important and symbolic’: US vice-president Mike Pence vaccinated for Covid – video

The US vice-president, Mike Pence, received his Covid-19 vaccine on Friday morning. Dr Anthony Fauci, who was present for the 'symbolic' inoculation, said it should serve as an example for all Americans called to do so to get vaccinated. 

US deaths from coronavirus topped 3,000 for a third straight day and the country reported a record number of new infections

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Covid is a chance to build a world where everyone has access to basic vaccines | David Miliband and Anuradha Gupta

Preventable diseases still plague those missing out on vaccines. Efforts to halt coronavirus could help crack this issue

The massive public, private and foundation investments in a coronavirus vaccine are producing results at a record pace. And countries are reacting accordingly. A recent global assessment of purchasing agreements for Covid-19 vaccines reveals that high-income countries, as well as a few middle-income countries with high manufacturing capacity, have already bought enough doses for their populations.

But delivery of the vaccine needs a new level of focus. This is especially the case for populations in poor and war-torn countries, where the health system is weak or nonexistent. Even before the pandemic, approximately 20 million infants a year, often some of the most vulnerable in the world, were missing out on basic vaccines. For example, there are estimated to be more than 10.6 million children in the world’s poorest countries who in 2019 did not receive even a first dose of a diphtheria-pertussis-tetanus vaccine (DPT).

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Ardern unveils New Zealand Covid vaccine deals as economy rebounds

Prime minister says 15m courses secured from four providers as part of country’s largest ever immunisation programme

New Zealand has ordered 15m courses of Covid-19 vaccine from four providers as the country approaches the end of 2020 on a promising note, with a recovering economy and plans to open numerous travel corridors in the new year.

On Thursday, the prime minister, Jacinda Ardern, confirmed the treatment would be free for everyone, with health workers and border officials prioritised. The vaccine will be made available in the second quarter of next year.

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US Covid vaccine shipments face delay as storm expected to pummel east coast

Treacherous storm set to hit states from Virginia to Massachusetts today as 3,019 people die in the last 24 hours

Continued shipments of the vital coronavirus vaccine around the US face delay as a monster winter storm is set to pummel states from Virginia to Massachusetts later Wednesday, even as the US suffered its third deadliest day of the pandemic.

A total of 3,019 people died because of coronavirus in the last 24 hours, the third highest total since the first cases were recorded in the US as far back as January.

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The great project: how Covid changed science for ever

The emergence of a novel coronavirus prompted a wave of global collaboration that has led to vaccines, treatments and the promise of new discoveries

For scientists, 5 January was a turning point in the fight against the coronavirus. That day, a team led by Prof Yong-Zhen Zhang at Fudan University in Shanghai sequenced the genetic code of the virus behind Wuhan’s month-long pneumonia outbreak. The process took about 40 hours. Having analysed the code, Zhang reported back to the Ministry of Health. The pathogen was a novel coronavirus similar to Sars, the deadly virus that sparked an epidemic in 2003. People should take precautions, he warned.

The Chinese government had imposed an embargo on information about the outbreak and Zhang and his co-workers were under pressure not to publish the code. The blackout couldn’t hold. On 8 January, news broke about the nature of the pathogen and was confirmed a day later by Chinese authorities. To sit on the code now seemed ridiculous.

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Coronavirus: key moments – timeline

From December 2019, when an unknown virus was found in China, to the release of vaccines for Covid-19 – here are the points where momentum shifted

From December 2019, when an unknown virus was found in China, to the release of vaccines for Covid-19, it has been an extraordinary year. Here’s how the momentum shifted

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Bolsonaro branded ‘homicidally negligent’ over Brazil’s vaccine planning

President accused of ignoring China-produced Covid vaccine because of political expediency

Jair Bolsonaro is facing a furious backlash over what critics are calling his “homicidally negligent” failure to prepare a coherent coronavirus vaccination programme as Brazil’s death toll again soars.

More than 181,000 Brazilians have died from the disease the president calls “a little flu”, with Latin America’s biggest economy now careering into a painful second wave.

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Covid vaccines roll out of Pfizer plant in US but Trump says he is not taking it yet

President says he is not scheduled to take vaccine as the most complex distribution project ever in the US gets underway

Trucks hauling trailers loaded with suitcase–sized containers of Covid-19 vaccine rolled out of Pfizer’s manufacturing facility in Kalamazoo, Michigan, on Sunday – launching the largest and most complex vaccine distribution project in the US.

However, public confidence in the vaccine risked being eroded after President Donald Trump – who has had Covid – said he was “not scheduled to take the vaccine” but would do so “at the appropriate time”.

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‘There are many roadblocks’: Fears grow over US Covid-19 vaccine rollout

States will soon begin distributing a vaccine with plans that vary widely, lack federal funding and are often opaque

Eleven hospitals in Kentucky will receive doses of a Covid-19 vaccine developed by Pfizer, perhaps as soon as Monday. Dr Nichelle Jadhav’s hospital is not one of them and she is confused. And she is not alone.

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Oxford Covid vaccine to be combined with Sputnik jab for trial

UK and Russian scientists to explore whether vaccines given together improves efficacy

UK and Russian scientists are to test whether combining shots of the Oxford/AstraZeneca and Sputnik V coronavirus vaccines could result in better protection than two doses of the same one.

Trials will start by the end of the year, the Russian Direct Investment Fund (RDIF), which funded the development of the Sputnik V vaccine by Russia’s Gamaleya Institute, said on Friday. AstraZeneca confirmed that it was considering how it could assess combinations of different vaccines, and would soon begin exploring with the Gamaleya Institute whether their two vaccines could be successfully combined.

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South Africa’s chief justice unrepentant for linking Covid vaccines to satanism

Concerns surface that people might avoid having jabs as result of comments by Mogoeng Mogoeng

South Africa’s chief justice has dismissed concerns that he may be endangering people’s health by linking coronavirus vaccines to a “satanic agenda”.

The comment by Mogoeng Mogoeng marked the first time since the outbreak of the pandemic that a senior judge had aired such preoccupations.

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