Inside Oxford’s coronavirus vaccine development

From a small discovery to producing at scale, photojournalist David Levene documents the groundbreaking work of the scientists of Oxford University during the development of a vaccine which is now poised for approval by medicines regulators

From the moment the coronavirus spilled out of China and spread around the world, the great hope for the return of normal life lay with safe and effective vaccines. While wearing masks and washing hands helped to reduce the flood of infections, they would never be enough to hold back the tide. Social distancing – a phrase that does nothing to convey the hardship of the act – suppresses the virus, no doubt. But what kind of life is a life lived apart?

Continue reading...

Moderna vaccine shipments begin as US reels under Covid surge

Workers began processing shipments of the second US Covid-19 vaccine on Sunday, but across the country the situation remained severe.

Related: Two authorized vaccines – here's what you need to know.

Continue reading...

Belgian minister tweets EU’s Covid vaccine price list to anger of manufacturers

Pharmaceutical companies complain of breach of confidentiality after amount EU has agreed to pay for leading vaccines goes public

A Belgian minister has blown the lid off a sensitive and commercial secret – the price that the EU has agreed to pay for the leading Covid vaccines.

Belgium’s budget state secretary, Eva De Bleeker, posted the price list on Twitter, with the amounts of each vaccine that her country intends to buy from the EU. The tweet was quickly deleted, but not soon enough to prevent interested parties taking screenshots, which have now made it public knowledge.

Continue reading...

‘Important and symbolic’: US vice-president Mike Pence vaccinated for Covid – video

The US vice-president, Mike Pence, received his Covid-19 vaccine on Friday morning. Dr Anthony Fauci, who was present for the 'symbolic' inoculation, said it should serve as an example for all Americans called to do so to get vaccinated. 

US deaths from coronavirus topped 3,000 for a third straight day and the country reported a record number of new infections

Continue reading...

Covid is a chance to build a world where everyone has access to basic vaccines | David Miliband and Anuradha Gupta

Preventable diseases still plague those missing out on vaccines. Efforts to halt coronavirus could help crack this issue

The massive public, private and foundation investments in a coronavirus vaccine are producing results at a record pace. And countries are reacting accordingly. A recent global assessment of purchasing agreements for Covid-19 vaccines reveals that high-income countries, as well as a few middle-income countries with high manufacturing capacity, have already bought enough doses for their populations.

But delivery of the vaccine needs a new level of focus. This is especially the case for populations in poor and war-torn countries, where the health system is weak or nonexistent. Even before the pandemic, approximately 20 million infants a year, often some of the most vulnerable in the world, were missing out on basic vaccines. For example, there are estimated to be more than 10.6 million children in the world’s poorest countries who in 2019 did not receive even a first dose of a diphtheria-pertussis-tetanus vaccine (DPT).

Continue reading...

Ardern unveils New Zealand Covid vaccine deals as economy rebounds

Prime minister says 15m courses secured from four providers as part of country’s largest ever immunisation programme

New Zealand has ordered 15m courses of Covid-19 vaccine from four providers as the country approaches the end of 2020 on a promising note, with a recovering economy and plans to open numerous travel corridors in the new year.

On Thursday, the prime minister, Jacinda Ardern, confirmed the treatment would be free for everyone, with health workers and border officials prioritised. The vaccine will be made available in the second quarter of next year.

Continue reading...

US Covid vaccine shipments face delay as storm expected to pummel east coast

Treacherous storm set to hit states from Virginia to Massachusetts today as 3,019 people die in the last 24 hours

Continued shipments of the vital coronavirus vaccine around the US face delay as a monster winter storm is set to pummel states from Virginia to Massachusetts later Wednesday, even as the US suffered its third deadliest day of the pandemic.

A total of 3,019 people died because of coronavirus in the last 24 hours, the third highest total since the first cases were recorded in the US as far back as January.

Continue reading...

The great project: how Covid changed science for ever

The emergence of a novel coronavirus prompted a wave of global collaboration that has led to vaccines, treatments and the promise of new discoveries

For scientists, 5 January was a turning point in the fight against the coronavirus. That day, a team led by Prof Yong-Zhen Zhang at Fudan University in Shanghai sequenced the genetic code of the virus behind Wuhan’s month-long pneumonia outbreak. The process took about 40 hours. Having analysed the code, Zhang reported back to the Ministry of Health. The pathogen was a novel coronavirus similar to Sars, the deadly virus that sparked an epidemic in 2003. People should take precautions, he warned.

The Chinese government had imposed an embargo on information about the outbreak and Zhang and his co-workers were under pressure not to publish the code. The blackout couldn’t hold. On 8 January, news broke about the nature of the pathogen and was confirmed a day later by Chinese authorities. To sit on the code now seemed ridiculous.

Continue reading...

Coronavirus: key moments – timeline

From December 2019, when an unknown virus was found in China, to the release of vaccines for Covid-19 – here are the points where momentum shifted

From December 2019, when an unknown virus was found in China, to the release of vaccines for Covid-19, it has been an extraordinary year. Here’s how the momentum shifted

Continue reading...

Bolsonaro branded ‘homicidally negligent’ over Brazil’s vaccine planning

President accused of ignoring China-produced Covid vaccine because of political expediency

Jair Bolsonaro is facing a furious backlash over what critics are calling his “homicidally negligent” failure to prepare a coherent coronavirus vaccination programme as Brazil’s death toll again soars.

More than 181,000 Brazilians have died from the disease the president calls “a little flu”, with Latin America’s biggest economy now careering into a painful second wave.

Continue reading...

Covid vaccines roll out of Pfizer plant in US but Trump says he is not taking it yet

President says he is not scheduled to take vaccine as the most complex distribution project ever in the US gets underway

Trucks hauling trailers loaded with suitcase–sized containers of Covid-19 vaccine rolled out of Pfizer’s manufacturing facility in Kalamazoo, Michigan, on Sunday – launching the largest and most complex vaccine distribution project in the US.

However, public confidence in the vaccine risked being eroded after President Donald Trump – who has had Covid – said he was “not scheduled to take the vaccine” but would do so “at the appropriate time”.

Continue reading...

‘There are many roadblocks’: Fears grow over US Covid-19 vaccine rollout

States will soon begin distributing a vaccine with plans that vary widely, lack federal funding and are often opaque

Eleven hospitals in Kentucky will receive doses of a Covid-19 vaccine developed by Pfizer, perhaps as soon as Monday. Dr Nichelle Jadhav’s hospital is not one of them and she is confused. And she is not alone.

Continue reading...

Oxford Covid vaccine to be combined with Sputnik jab for trial

UK and Russian scientists to explore whether vaccines given together improves efficacy

UK and Russian scientists are to test whether combining shots of the Oxford/AstraZeneca and Sputnik V coronavirus vaccines could result in better protection than two doses of the same one.

Trials will start by the end of the year, the Russian Direct Investment Fund (RDIF), which funded the development of the Sputnik V vaccine by Russia’s Gamaleya Institute, said on Friday. AstraZeneca confirmed that it was considering how it could assess combinations of different vaccines, and would soon begin exploring with the Gamaleya Institute whether their two vaccines could be successfully combined.

Continue reading...

South Africa’s chief justice unrepentant for linking Covid vaccines to satanism

Concerns surface that people might avoid having jabs as result of comments by Mogoeng Mogoeng

South Africa’s chief justice has dismissed concerns that he may be endangering people’s health by linking coronavirus vaccines to a “satanic agenda”.

The comment by Mogoeng Mogoeng marked the first time since the outbreak of the pandemic that a senior judge had aired such preoccupations.

Continue reading...

FDA advisory panel recommends approval of Pfizer Covid vaccine for emergency use

Recommendation signals formal FDA approval for Pfizer/BioNTech vaccine in the US could be imminent

An advisory panel to the US Food and Drug Administration has recommended the emergency approval of a Covid-19 vaccine developed by Pfizer and BioNTech.

The recommendation is expected to signal that the first approval of a Covid-19 vaccine for use in the US is imminent. That would mark a major milestone in a pandemic that has killed more than 285,000 Americans and 1.5 million people globally.

Continue reading...

Rich countries leaving rest of the world behind on Covid vaccines, warns Gates Foundation

Deals struck by wealthy nations to secure treatments could leave the world’s poorest people unvaccinated without urgent action

It could be too late for any kind of fair distribution of coronavirus vaccines because of the deals already made by rich countries, according to Mark Suzman, chief executive of the Bill & Melinda Gates Foundation.

Despite the unprecedented pace of scientific progress on the development of vaccines, he said it remains “really, really complicated” to ensure they are produced and distributed fairly.

Continue reading...

‘Deeply boring’: Martin Kenyon puzzled by vaccine video fame

TV interview outside hospital after getting jab makes 91-year-old an internet hit

A 91-year-old man whose interview with CNN after he was vaccinated for coronavirus became an internet hit said he was bemused by the commotion he caused by talking about the jab, and described anti-vaxxers as “very silly”.

Martin Kenyon, 91, was outside Guy’s hospital in London after receiving the Pfizer Covid vaccine when he encountered the CNN correspondent Cyril Vanier. Asked how it felt to be one of the first people in the world to receive the jab, he said: “I don’t think I feel much at all, except that I hope that I’m not going to have the bloody bug now.”

Continue reading...

Chinese Covid-19 vaccine has 86% efficacy, UAE says

First results released from trial of Sinopharm shot involving 31,000 people

The United Arab Emirates said a Chinese coronavirus vaccine tested in the federation of sheikhdoms has 86% efficacy, in a statement that provided few details but marked the first public release of information on the performance of the shot.

The announcement brought yet another contender into the worldwide race for a vaccine to end the pandemic, a scientific effort in which China and Russia are competing with western firms to develop an effective inoculation.

Continue reading...

Brexit: Johnson claims Brussels wants power to ‘punish’ UK if it does not implement future EU laws – live

Prime minister tells Commons conditions for trade deal are unacceptable before later heading to Brussels for last-ditch talks

Scotland came close to eliminating Covid during the first nationwide lockdown, according to genomic sequencing for Sage of 5,000 samples of the virus, the Scottish government believes.

Jason Leitch, the Scottish government’s national clinical director, said analysis by scientists in Edinburgh, Glasgow and St Andrews on the COG-UK consortium found that around 300 different strains of the virus were circulating in Scotland during the first wave.

That allows us to say this did get us incredibly close to eliminating the virus in our communities, but as we opened up, inevitably people began to travel across the UK [and] travel abroad. New strains were imported again into Scotland.

[This] indicates that, while lockdown in Scotland is directly linked with the first wave case numbers being brought under control, travel-associated imports (mostly from Europe or other parts of the UK) following the easing of lockdown are responsible for seeding the current epidemic population.

This demonstrates that the impact of stringent public health measures can be compromised if, following this, movements from regions of high to low prevalence are not minimised.

Public Health Wales has recorded 2,238 further coronavirus cases. That is a new record daily high for recorded cases. The previous daily record was 2,021, on Monday. A week ago today the figure was 1,480.

There have also been 31 further deaths. A week ago today the figure was 51.

The rapid COVID-19 surveillance dashboard has been updated.

https://t.co/zpWRYSUbfh
https://t.co/HSclxpZjBh

Read our daily statement here: https://t.co/u6SKHz0zsG pic.twitter.com/sAk8sFy5NQ

Continue reading...