Editor Brian Harrod Provides Comprehensive up-to-date news coverage, with aggregated news from sources all over the world from the Roundup Newswires Network
Recommendation signals formal FDA approval for Pfizer/BioNTech vaccine in the US could be imminent
An advisory panel to the US Food and Drug Administration has recommended the emergency approval of a Covid-19 vaccine developed by Pfizer and BioNTech.
The recommendation is expected to signal that the first approval of a Covid-19 vaccine for use in the US is imminent. That would mark a major milestone in a pandemic that has killed more than 285,000 Americans and 1.5 million people globally.
It could be too late for any kind of fair distribution of coronavirus vaccines because of the deals already made by rich countries, according to Mark Suzman, chief executive of the Bill & Melinda Gates Foundation.
Despite the unprecedented pace of scientific progress on the development of vaccines, he said it remains “really, really complicated” to ensure they are produced and distributed fairly.
A 91-year-old man whose interview with CNN after he was vaccinated for coronavirus became an internet hit said he was bemused by the commotion he caused by talking about the jab, and described anti-vaxxers as “very silly”.
Martin Kenyon, 91, was outside Guy’s hospital in London after receiving the Pfizer Covid vaccine when he encountered the CNN correspondent Cyril Vanier. Asked how it felt to be one of the first people in the world to receive the jab, he said: “I don’t think I feel much at all, except that I hope that I’m not going to have the bloody bug now.”
The United Arab Emirates said a Chinese coronavirus vaccine tested in the federation of sheikhdoms has 86% efficacy, in a statement that provided few details but marked the first public release of information on the performance of the shot.
The announcement brought yet another contender into the worldwide race for a vaccine to end the pandemic, a scientific effort in which China and Russia are competing with western firms to develop an effective inoculation.
Scotland came close to eliminating Covid during the first nationwide lockdown, according to genomic sequencing for Sage of 5,000 samples of the virus, the Scottish government believes.
Jason Leitch, the Scottish government’s national clinical director, said analysis by scientists in Edinburgh, Glasgow and St Andrews on the COG-UK consortium found that around 300 different strains of the virus were circulating in Scotland during the first wave.
That allows us to say this did get us incredibly close to eliminating the virus in our communities, but as we opened up, inevitably people began to travel across the UK [and] travel abroad. New strains were imported again into Scotland.
[This] indicates that, while lockdown in Scotland is directly linked with the first wave case numbers being brought under control, travel-associated imports (mostly from Europe or other parts of the UK) following the easing of lockdown are responsible for seeding the current epidemic population.
This demonstrates that the impact of stringent public health measures can be compromised if, following this, movements from regions of high to low prevalence are not minimised.
Public Health Wales has recorded 2,238 further coronavirus cases. That is a new record daily high for recorded cases. The previous daily record was 2,021, on Monday. A week ago today the figure was 1,480.
There have also been 31 further deaths. A week ago today the figure was 51.
The rapid COVID-19 surveillance dashboard has been updated.
People with a history of significant allergic reactions should not receive the Covid vaccine, the medicines regulator has said, after two NHS workers experienced symptoms on Wednesday.
Both of the NHS staff carry adrenaline autoinjectors, suggesting they have suffered reactions in the past. These kind of devices, of which the best-known brand is the EpiPen, administer a swift adrenaline boost to counter allergic reactions that occur when some people, for instance, eat nuts.
Martin Kenyon, 91, was outside Guy’s Hospital in London after getting the Pfizer Covid vaccine when he was chanced upon by CNN correspondent Cyril Vanier. Asked how it felt to be one of the first people in the world to receive the jab, Kenyon said:’ I don’t think I feel much at all, except that I hope that I’m not going to have the bloody bug now.’
During the interview, which went viral after being shared by CNN’s Oliver Darcy on Twitter, Kenyon added that he intended to hug his family for Christmas. ‘I’m going home to tell them now. Nobody knows. You’re the first to know,’ he told Vanier.
The Oxford/AstraZeneca Covid vaccine has efficacy of 90% in a small group who got a half-dose first, but only 62% in the majority, full trial data newly published in the Lancet has confirmed.
The results may create a quandary for regulatory bodies, which will have to decide on how the vaccine should be used if they approve it.
Margaret Keenan, 90, became the first patient in the world to receive the Pfizer Covid-19 jab following its clinical approval as the NHS launched its biggest ever vaccine campaign on Tuesday.
Keenan received the jab at about 6.45am in Coventry, marking the start of a historic mass vaccination programme.
A trial is likely to go ahead in January to find out whether mixing and matching Covid vaccines gives better protection than two doses of the same one, the head of the British government’s taskforce has said.
The Pfizer/BioNTech Covid jab is an mRNA vaccine. Essentially, mRNA is a molecule used by living cells to turn the gene sequences in DNA into the proteins that are the building blocks of all their fundamental structures. A segment of DNA gets copied (“transcribed”) into a piece of mRNA, which in turn gets “read” by the cell’s tools for synthesising proteins.
The arrival of the Pfizer/BioNTech Covid vaccine marks the ‘beginning of the end’ of the pandemic, the health secretary said, as hospitals across the country prepare to begin vaccinating the public on 8 December.
About 800,000 doses are expected to be available within the first week, with care home residents and carers, the over-80s and some health workers first to receive the shots
The World Health Organization is holding discussions on Monday about the feasibility of trials in which healthy young volunteers are deliberately infected with coronavirus to hasten vaccine development – amid questions over whether they should go ahead given the promising data from the frontrunner vaccine candidates.
Some scientists have reservations about exposing volunteers to a virus for which there is no cure, although there are treatments that can help patients. However, proponents argue that the risks of Covid-19 to the young and healthy are minimal, and the benefits to society are high.
Batches of the Covid vaccine have begun to arrive in hospitals around the UK, ready for the first jabs on Tuesday in what NHS England’s medical director warned would be the largest and most complex vaccination campaign in the country’s history.
The UK’s record-breaking approval of the vaccine and the rapid start of immunisation against Covid-19 did not mean the end of the pandemic was in sight, said Prof Stephen Powis. It would be a marathon and not a sprint, he said.
In the early afternoon of 3 January this year, a small metal box was delivered to the Shanghai Public Health Clinical Centre addressed to virus expert Prof Zhang Yongzhen. Inside, packed in dry ice, were swabs from a patient who was suffering from a novel, occasionally fatal respiratory illness that was sweeping the city of Wuhan. Exactly what was causing terrifying rises in case numbers, medical authorities wanted to know? And how was the disease being spread?
Tens of millions of doses of the Covid-19 vaccine manufactured in Belgium will be flown to Britain by military aircraft to avoid delays at ports caused by Brexit, under contingency plans being developed by the government.
Both the Department of Health and Social Care (DHSC) and senior sources at the Ministry of Defence (MoD) confirmed to the Observer on Saturday that large consignments would be brought in from 1 January by air if road, rail and sea routes were subject to widely expected delays after that date.
Vaccine could be in use by 2024 if next year’s human trials are successful
The Oxford team that has produced a successful coronavirus vaccine is about to enter the final stage of human trials in its quest for an inoculation against malaria.
The Jenner Institute director, Prof Adrian Hill, said the malaria vaccine would be tested on 4,800 children in Africa next year after early trials yielded promising results.
Moscow’s coronavirus taskforce said on Saturday that it was distributing the Sputnik V vaccine to 70 clinics, marking Russia’s first mass Covid-19 immunisation.
The taskforce said the Russian-made vaccine would be made available first to doctors and other medical workers, teachers and social workers because they ran the highest risk of exposure to the disease.
World Health Organization leaders have warned vaccines do not mean the end of the coronavirus pandemic, and renewed their advice to follow guidelines during the Christmas and new year period
The Medicines and Healthcare Products Regulatory Authority (MHRA) in the UK has not had a round of applause from anyone other than the UK’s politicians and the vaccine companies. It gave temporary authorisation to the Pfizer/BioNTech vaccine on Wednesday and within hours, the European Medicines Agency (EMA) put out a stiff statement implying more work was needed than the UK regulator had done. Its own decision could come as late as 29 December. It may well have been needled by the crowing of the health secretary, Matt Hancock, who claimed the fast approval as a Brexit triumph. He had to backtrack. The MHRA’s chief executive, June Raine, pointed out that the agency had simply taken advantage of a provision that any country in Europe could use, to fast-track approval in a pandemic.
Analysis: Vaccine hesitancy is growing, thanks in part to social media misinformation. Time for the Elvis approach?
The statement by the US president-elect, Joe Biden, that he would be happy to be publicly vaccinated against coronavirus to encourage people to follow suit – following similar pledges from Barack Obama, George W Bush and Bill Clinton – highlights a fundamental concern in global health circles.
Vaccine hesitancy – as well as anti-vaccination activism, sometimes promoted by celebrities – is growing. Countries that were once measles-free are seeing new cases due to suspicion over vaccination. Vaccine hesitancy was listed a year ago as one of the World Health Organization’s 10 global health threats to watch, alongside Ebola and the threat of a global influenza pandemic. Coronavirus came instead.