Omicron is sneaky. It could be fatal for us – or for our faith in government | Francois Balloux

The week ahead will be pivotal as we track the spread of the new variant and discover its potential legacy

The emergence and rapid spread of the Omicron Sars-CoV-2 variant feels like a flashback to last year’s grim festive season when much of the world went into lockdown to avert the worst of the Alpha variant wave. But though the sense of eerie, impending doom feels familiar, the epidemiological and political situations are different from one year ago.

The Omicron wave represents a key turning point in the pandemic. But no plausible outcome looks particularly auspicious – it feels largely like a lose-lose deal. If if turns out to be roughly as severe as previous pandemic waves, it might normalise harsh mitigation measures and render the prospect of a return to post-pandemic normality fairly remote. If it turned out to be milder than feared, this could spell the end of lockdowns with Covid-19 on its way into endemicity. The cost would be a loss of trust in political and public health authorities, which may make it difficult to deal with future threats.

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Will Omicron kill Christmas? How science stacks up in boosters v Covid variant battle

Analysis: UK faces grim winter if vaccines offer poor overall protection, but if the virus has weak powers to evade immunity, hospital cases can be contained

Two competing forces will determine Omicron’s impact on the nation over the next few weeks. The power of booster jabs to give last-minute protection against Covid-19 will be pitted against the new variant’s ability to elude existing immunity. The outcome will decide whether our festive season is going to be muted or miserable.

If enough arms are jabbed with booster vaccines, while Omicron turns out to have poor powers to evade immunity, then there is hope hospital cases will be contained and the NHS will be protected. Severe restrictions in the new year – including the prospect of lockdowns – could be avoided.

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Omicron patient hospitalised in NSW as Queensland prepares for thousands of cars to cross border

Covid vaccine booster shots also fast-tracked on day of large protests in capital cities to oppose mandates

A person in New South Wales has been admitted to hospital infected with the Omicron variant of Covid-19, the first Omicron patient to be hospitalised since it arrived in Australia last month.

It comes as thousands of protesters marched through capital cities on Sunday to oppose vaccine mandates, and Western Australia and Queensland prepared to reopen their borders.

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Scientists fear falling trust in Boris Johnson could harm bid to curb Omicron surge

Researchers say new rules may be needed to cut deaths, but there are concerns that ‘fed-up’ people will ignore government

Ministers announced a huge expansion of the booster vaccine campaign on Saturday night, amid warnings that further restrictions will be needed imminently to prevent tens of thousands of deaths.

With new Covid measures being discussed in Whitehall and claims of people being turned away from booster walk-in centres, third jabs will be opened up to those in their 30s from Monday in England. Those who had their second jab three months ago or more will be eligible.

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Confusion over booster eligibility in England as people in 30s book Covid jabs

Apparent glitch allows younger people to book vaccinations before they were expected to qualify

There was confusion on Saturday about which age groups in England are now eligible to book a booster jab with the NHS, after an apparent glitch allowed younger people to book before they were expected to qualify.

People aged 30 and over in England were expected to be able to book a Covid-19 booster from Monday as long as it has been three months since their second vaccine dose, but many 30-somethings reported on social media on Saturday that they had been able to book their appointments already.

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Covid live: 633 new Omicron cases detected in UK with overall daily infections at 54,073

UK health officials urge those eligible to get third vaccine dose; Taiwan and Mauritius detect first cases of new variant

What’s the truth about lockdown-busting parties at No 10? Don’t ask Shagatha Christie, writes Marina Hyde in her column this week.

Here are some extracts:

There was simply no other place a Johnson government would ever end up but mired in rampant lies, chaos, negligence, financial sponging and the live evisceration of public service. To the Conservatives and media outriders somehow only now discovering this about their guy, I think we have to say: you ordered this. Now eat it.

Regrettably, though, space constraints must end our recap of the week here. But on it all goes, as Omicron closes in. We’ll play out with a reminder that in a pandemic that has so far killed 146,000 of the Britons who these people are supposed to be in politics to serve, the absolutely vital public health message has now TWICE been most fatally undermined by people who worked at the very heart of No 10 with Boris Johnson. That is absolutely a disgrace, and absolutely not a coincidence.

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Tens of thousands protest against compulsory Covid jabs in Austria

Crowds in Vienna demonstrate against mandatory vaccines and confinement orders for unvaccinated

Tens of thousands of people have gathered in Austria’s capital Vienna to protest against mandatory Covid vaccines and home confinement orders for those who have not yet received the jabs.

Police said an estimated 44,000 people attended the demonstration on Saturday, the latest in a string of huge weekend protests since Austria last month became the first EU country to say it would make Covid vaccinations mandatory.

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As Covid mutates, the vaccine makers are adapting too

Focus on the exciting potential of T-cell immunity is spurring the sector on to create a new generation of jabs

The speed at which scientists worked to develop the first Covid jabs was unprecedented. Just nine months after the UK went into lockdown, 90-year-old Margaret Keenan officially became the first person in the world outside a trial to receive the Pfizer/BioNTech vaccine. But the virus is mutating, and the emergence of the Omicron variant last month is already focusing attention on the next generation of jabs.

So what do we know about the new Covid-19 vaccines? One change is with delivery mechanisms, such as San Francisco firm Vaxart’s vaccine-in-a-pill, and Scancell’s spring-powered injectors that pierce the skin without a needle. But the biggest development is in T-cell technology. Produced by the bone marrow, T-cells are white blood cells that form a key part of the immune system. While current vaccines mainly generate antibodies that stick to the virus and stop it infecting the body, the new vaccines prime T-cells to find and destroy infected cells, thus preventing viral replication and disease. (The current vaccines also produce a T-cell response, but to a lesser extent.)

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From hippos to hamsters: how Covid is affecting creatures great and small

Scientists are racing to assess the spread of the virus in wild and domestic animals, and the threat it could pose to us

A year ago humanity embarked on a project to vaccinate every person against Covid-19. But in recent months a shadow vaccination campaign has also been taking place. From giraffes to snow leopards, gorillas to sea lions, zoos around the world have been inoculating their animals with an experimental Covid vaccine as an insurance policy against what they fear could be a similarly fatal illness for certain mammals.

Meanwhile, veterinary scientists have been scrambling to understand the scale of Covid-19 infection in our furry household companions, and what the consequences could be for their health – and our own.

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Why uncontrolled HIV may be behind the emergence of Omicron

Analysis: experts say weakened immune systems may give rise to new Covid variants – so HIV prevention could be key to stopping coronavirus

Where did Omicron come from? By all accounts it is a weird variant. Though highly mutated, it descended not from one of the other variants of concern, such as Alpha, Beta or Delta, but from coronavirus that was circulating maybe 18 months ago. So where has it been all this time? And why is it only wreaking havoc now?

Researchers are exploring a number of hunches. One is that Omicron arose in a remote region of southern Africa but failed to spread until now. Another is that it evolved in infected animals, such as rats, and then crossed back into humans. But a third explanation is gaining ground as more data come to light, that Omicron arose in a person with a weakened immune system: someone having cancer treatment perhaps, an organ transplant patient or someone with uncontrolled HIV.

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Victoria records 13 deaths and NSW three; Qld changes quarantine rules – as it happened

Sydney pub and club at centre of scare. Bushfire rages in Margaret River in Western Australia. This blog is now closed

Two of the government’s biggest departments were found to have broken freedom of information law within a month of each other, prompting the watchdog to demand urgent explanations and reforms from both, documents show.

The Office of the Australian Information Commissioner (OAIC) last month found the Department of Foreign Affairs and Trade breached the law by dragging out and eventually refusing a request by lawyer and FoI specialist Peter Timmins, documents seen by Guardian Australia show.

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Javid advised to take ‘stringent’ Covid measures within a week, leak reveals

Exclusive: Health officials say urgent action needed to avoid mass hospitalisations and overwhelming the NHS

Britain’s top public health officials have advised ministers that “stringent national measures” need to be imposed by 18 December to avoid Covid hospitalisations surpassing last winter’s peak, according to documents leaked to the Guardian.

Sajid Javid, the health secretary, received a presentation from the UK Health and Security Agency (UKHSA) on Tuesday warning that even if the new Omicron variant leads to less serious disease than Delta, it risks overwhelming the NHS with 5,000 people admitted to hospital a day.

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Arrival of 1bn vaccine doses won’t solve Africa’s Covid crisis, experts say

Concerns over equipment shortages, bottlenecks and hesitancy on continent with 7.5% vaccine coverage

With 1bn doses of Covid vaccines expected to arrive in Africa in the coming months, concern has shifted to a global shortage of equipment required to deliver them, such as syringes, as well as insufficient planning in some countries that could create bottlenecks in the rollout.

After a troubled start to vaccination programmes on the continent, health officials are examining ways to encourage take-up as some countries have had to throw away doses.

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My family has a vaccine refusenik – should we still get together at Christmas? | Ask Annalisa Barbieri

You can’t force him to get vaccinated – but equally, he can’t force you to spend time with him. Face this head on and explain how you feel

I’m sure I’m not the only one who’s faced this difficulty this year. One of my family members, who’s in his 40s, has consistently refused to be vaccinated against Covid and will not be moved from his position. He will not explain his reasons for rejecting the vaccine, whether it is ideological or simply rebellion against the so-called “nanny state”.

He has already been (politely but firmly) excluded from one family get-together as a result of his intransigence. We have explained that he is not being rejected personally, but there are concerns within the family about his vulnerability to catching the virus and transmitting the infection to the children and their grandparents.

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Digested week: when is a party not a party? You could ask Dilyn the Dog | John Crace

The stories about Downing Street happenings that never happened are becoming increasingly surreal

Last Christmas was probably the worst my wife and I had spent together in all the years we have been together. We had long since accepted there was no chance of our daughter coming over from the US but the final straw was when the Covid guidelines were changed and we were unable even to see our son and his girlfriend for the day. So we glumly ate a small chicken and watched TV before sneaking off to bed round about 9pm. Now it’s looking as if we were mugs for sticking to the rules as those inside No 10 were ignoring them by holding a series of after-work parties. So far the government has not tried to deny that these gatherings took place – other than to say whatever happened was not a party – and its lines of defence have become increasingly ropey. First we have had Boris Johnson saying no one cared what happened a year ago and that an investigation wasn’t in the public interest. This was a line pursued by Dominic Raab, the justice secretary, on the Marr programme when he said the police didn’t bother to investigate crimes that had happened in the past – news for watchers of Silent Witness and Unforgotten. Though possibly Raab is under the impression the only crimes worth solving are those that have yet to be committed. Then on today’s media round, we had Kit Malthouse, the policing minister, saying he had been assured that even if a party had taken place – which he couldn’t confirm as he hadn’t been there – it definitely took place within the guidelines because the music had been very quiet and someone had opened the windows. Or something. Despite the fact that any gatherings were banned. No 10 just doesn’t seem to get how angry everyone is about this. Nor how many will think twice about breaking the rules if they are changed again before Xmas.

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Covid live: Israel extends travel ban over Omicron; German parliament debates healthcare vaccine mandate

Ten day extension to restrictions announced as Israel detects 21 cases; lawmakers debate first of two German vaccine mandate laws

Fury over the release of a video showing Downing Street staffers joking about alleged lockdown breaches in the UK are only the latest scandal to rock British prime minister Boris Johnson’s premiership.

For days, a succession of government ministers batted away questions about whether an illegal party had been held in Downing Street last December during Covid restrictions that banned gatherings of more than 30 people. But on Tuesday night that all changed: a video emerged of Downing Street staffers appearing to joke about a party alleged to have been held inside No 10 just days earlier.

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Staff shortages are hobbling vaccination campaigns as demand runs high

Most Covid doses are now dispensed at pharmacies and some are struggling to manage the workload

Officials in the US are encouraging eligible adults to get boosters amid a new surge of the Covid-19 pandemic and the discovery of the Omicron variant, but some areas are facing shortages – not of the vaccines, but of pharmacy staff to administer them.

More than two in three Covid vaccines are now given at pharmacies, the White House has said, but pharmacies are facing a double bind of increased workloads and staffing shortages and are struggling to keep up with demand for vaccination appointments.

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Mouse bite may have infected Taiwan lab worker with Covid

Employee at high-security facility tests positive in island’s first local infection in weeks

Health officials in Taiwan are investigating whether a mouse bite may have been responsible for a laboratory worker testing positive for Covid, the island’s first local infection in weeks.

The authorities are scrambling to work out how the employee at Academia Sinica, the country’s top research institute, contracted the virus last month.

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Scientists use ostrich cells to make glowing Covid detection masks

Japanese researchers use bird antibodies to detect virus under ultraviolet light

Japanese researchers have developed masks that use ostrich antibodies to detect Covid-19 by glowing under ultraviolet light.

The discovery, by Yasuhiro Tsukamoto and his team at Kyoto Prefectural University in western Japan, could provide for low-cost testing of the virus at home.

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Biden faces vaccine mandate pushback from own party despite support of scientists

Two Democratic senators push back against president’s rules for large businesses as cases continue to rise in the US

Two Democratic senators have resisted Joe Biden’s vaccine-or-test mandate for large businesses, illustrating problems the US president faces even within a faction of his own party, despite having the support of scientists and public health experts.

The US Senate on Wednesday evening voted to overturn the mandate as new cases and hospitalizations continue rising in the country.

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