Coronavirus live news: Global death toll passes 1.5m

World passes grim tally with a death reported every nine seconds on average; Italy registers 993 new deaths and 23,255 new cases; Iran goes past 1m cases

More than 1.5 million people have lost their lives due to Covid-19 with one death reported every nine seconds on a weekly average, as vaccinations are set to begin in December in a handful of developed nations.

Reuters reports that half a million deaths occurred in just the last two months, indicating that the severity of the pandemic is far from over. Nearly 65 million people globally have been infected by the disease and the worst affected country, United States, is currently battling a third wave of coronavirus infections.

I actually believe they’re going to be the most difficult time in the public health history of this nation.

A partial lockdown will begin this weekend in the Gaza Strip after Covid-19 infections surged in the densely populated territory, Gaza’s interior ministry declared on Thursday.

Mosques, schools, universities and kindergartens - excluding high schools and nurseries - will be closed during the day, although many businesses will be allowed to remain open until a night-time curfew from 6pm to 8am forces Gazans to stay at home. There will be a full closure at weekends.

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‘The scientists have done it’: Boris Johnson hails Covid vaccine

PM says news brings ‘sure and certain knowledge’ that people can reclaim their lives

Boris Johnson has declared that the nation is no longer resting on the hope of a return to normality by spring but instead has the “certain knowledge” that people can reclaim their lives, as he hailed the arrival of the newly approved Covid-19 vaccine.

The prime minister told a Downing Street press conference on Wednesday that “the scientists have done it”, although he stressed that people should not get carried away with “over-optimism”, insisting that they continue to abide by the rules.

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UK coronavirus live: Boris Johnson leads Downing Street briefing after vaccine approved for use

Latest updates: PM holds press conference after earlier warning people not to ‘get hopes up too soon’ about early vaccination

Stevens is talking about the vaccination guidelines. (See 11.23am.)

The roll-out will be phased, he says.

Johnson urges people in tier 3 areas to take part in community testing.

And people should follow the restrictions, he says.

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France will carry out border checks to stop skiers from spreading Covid

Coronavirus clusters in Alpine resorts played key role in early spread of virus in Europe

France will carry out random border checks over the holiday season targeting French skiers on their way to and from foreign resorts – particularly Switzerland and Spain – where slopes stay open, the prime minister, Jean Castex, has said.

“The goal is to avoid French citizens getting contaminated. That will be done by performing random checks at the borders,” Castex told French television, adding that returning holidaymakers would be ordered to quarantine for seven days.

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UK approves Pfizer/BioNTech Covid vaccine for rollout next week

‘Historic moment’ allows mass immunisation, with 800,000 doses expected to be available next week

The UK has become the first western country to license a vaccine against Covid, opening the way for mass immunisation with the Pfizer/BioNTech vaccine to begin next week for those most at risk.

The vaccine has been authorised for emergency use by the Medicines and Healthcare products Regulatory Authority (MHRA), before decisions by the US and Europe. The MHRA was given power to approve the vaccine by the government under special regulations before 1 January, when it will become fully responsible for medicines authorisation in the UK after Brexit.

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Coronavirus live news: CDC suggests first vaccines to US healthcare workers; England enters tier system

US hospitalisations surge; New tier system replaces lockdown; BioNTech/Pfizer and Moderna file for EU approval of Covid-19 vaccine

The national accounts, released by the Australian Bureau of Statistics just now, shows that rise in seasonally adjusted chain volume measures, after a 7% fall in the June quarter.

In the US, a government panel on Tuesday formally recommended early doses of Covid-19 vaccines be given first to healthcare workers and long-term care facility residents in the US, generally seen as people who live in nursing homes and assisted living facilities.

Together, that group would represent roughly 23 million Americans, disproportionately including women, people of color and low-wage workers who makeup the healthcare labor force.

Related: CDC panel recommends giving Covid-19 vaccines to healthcare workers first

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Coronavirus live news: WHO says vaccines won’t prevent short-term surge; Putin orders start of mass inoculation

Health body says there won’t be enough doses to prevent new wave in cases in next six months; Russian president says programme should start next week

Morocco hopes to launch an ambitious vaccination campaign against the coronavirus by year-end, but its efforts have sparked suspicion and rumours in the country, hard-hit by the pandemic.

The North African kingdom is hoping to immunise 20 million adults against Covid-19 within three months, using vaccinations from China’s Sinopharm and a UK-sourced shot developed by AstraZeneca and Oxford University.

Boris Johnson might be persuaded to take a Covid-19 vaccination on television to show it is safe but he would not have one before those in greater need, his press secretary has said.

Johnson, 56, who spent time in intensive care earlier this year after contracting Covid-19, has hailed the UK approval of Pfizer’s vaccine as a global win and ray of hope.

I don’t think it would be something he would rule out.

But I think we also know that he wouldn’t want to take a jab that should be for someone who is extremely vulnerable, clinically vulnerable, and who should be getting it before him.

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China to collect first moon rocks since 1970s after successful probe landing

Chang’e-5 spacecraft completes 112-hour journey from Earth, according to Beijing’s space agency

A Chinese probe sent to the moon to bring back the first lunar samples in four decades has successfully landed, according to Beijing’s space agency.

China has poured billions into its military-run space programme, with hopes of having a crewed space station by 2022 and eventually sending humans to the moon.

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Coronavirus live news: US may begin vaccinations before Christmas; Vietnam sees first case in three months

WHO ‘will do everything’ to find Covid origin; Mexico and Brazil seeing ‘alarming’ case surge; Scott Atlas resigns as special adviser to Trump on coronavirus

Russia has reported a record 569 deaths linked to Covid-19 today, bringing the official death toll to 40,464.

Authorities also reported 26,402 new coronavirus infections in the last 24 hours, including 6,524 in the capital Moscow, bringing the national cumulative tally to 2,322,056.

Thanks to regular reader Scott Lafferty, who has been in touch to remind us that the Netherlands has today finally made face masks mandatory in indoor public spaces.

Face masks will be compulsory in all public buildings, shops, and stations from tomorrow as the coronavirus law comes into effect, and people who refuse to wear one face a fine of €95, reports Dutch News.

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DeepMind AI cracks 50-year-old problem of protein folding

Program solves scientific problem in ‘stunning advance’ for understanding machinery of life

Having risen to fame on its superhuman performance at playing games, the artificial intelligence group DeepMind has cracked a serious scientific problem that has stumped researchers for half a century.

With its latest AI program, AlphaFold, the company and research laboratory showed it can predict how proteins fold into 3D shapes, a fiendishly complex process that is fundamental to understanding the biological machinery of life.

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Coronavirus live news: Moderna to seek US and EU approval for vaccine; Italy records 672 new Covid-related deaths

Moderna reports a 100% success rate in preventing severe cases; Italy reports 672 new Covid-related deaths, a rise on Sunday’s figure

Turkey’s daily Covid-19 death toll hit a record high for an eighth consecutive day on Monday, with 188 fatalities in the last 24 hours.

The number of new coronavirus cases, including asymptomatic ones, over the past 24 hours also reached a record high of 31,219.

The state of Sao Paulo, home to Brazil’s biggest city, has imposed stricter social distancing measures as it wrestles to contain a fresh rise in Covid-19 cases.

Opening hours and capacities for bars, restaurants and shopping malls will be restricted in Brazil’s most populous state which has been the centre of the country’s coronavirus outbreak.

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Long Covid: ‘Is this now me forever?’

Months after coming down with the virus, Eleanor Morgan is still struggling with ‘long Covid’. What is it and how can the burden be eased?

One night in early March, I had a fever that reminded me of being a child. My pyjama top stuck to me with sweat, my joints ached and, at some point, the walls looked like they were breathing. The next morning I started coughing and didn’t stop. It was pre-lockdown and, taking pity on me (I live alone in London), a friend in the countryside offered to be nurse. En route, in Paddington Station, I longed to curl up like a cat beside the warmth of the Upper Crust stall. One morning, my friend told me she’d poked her head round the door throughout the night to check I hadn’t coughed my aorta up into the bed.

Back in London, as lockdown began, unpredictable spells of fatigue started to hit me. Was it Covid? I had no idea; only NHS staff were being tested then. But it didn’t feel like chest infections I’d known. There was a crushing feeling in my chest for weeks, as if my ribs were a pair of bellows being squeezed. Adding to the fun, I’m asthmatic. On two occasions, things felt hairy and I called 111. Each time I was summoned to A&E and given a nebuliser and steroids, which helped dramatically. But March became April, became May and the fatigue remained. Some days, it felt like a possession. I’d walk the dog in the morning then fall asleep on the sofa until 3pm. Eight months on, I still have mild, irregular breathlessness and chest tightness. I have been upgraded to a steroid inhaler that, generously, keeps giving me oral thrush. My GP thinks I may have long Covid.

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Life after Covid: will our world ever be the same?

From cities, to science, to politics, six Observer writers assess how a post-pandemic world will emerge into a new normal

Here are some things that the pandemic changed. It accustomed some people – those whose jobs allowed it – to remote working. It highlighted the importance of adequate living space and access to the outdoors. It renewed, through their absence, an appreciation of social contact and large gatherings. It showed up mass daily commuting for the dehumanising drain on energy and resources that it is.

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Camilla Pang: ‘You have to acknowledge the hilarity of what it is to be human’

Prize-winning author Camilla Pang talks about her autism and ADHD diagnoses and her desire to challenge myths about neurodiversity

This month Camilla Pang won the Royal Society book prize for her debut, Explaining Humans: What Science Can Teach Us about Life, Love and Relationships. She has a PhD in bioinformatics from UCL and works as a postdoctoral researcher. Dr Pang was diagnosed with autism spectrum disorder at the age of eight and attention deficit hyperactivity disorder at 26.

Why did you decide to write this book?
I inadvertently wrote the book in my PhD thesis on bioinformatics, and my supervisor, bless her, said this is great, but it doesn’t belong here. One of the things people on the autistic spectrum do is organise our world in a way that makes sense to us using objects and sequences. For me, those sequences involved looking at the fundamentals of matter, and what that meant in terms of science. Even if I was just kicking a pile of leaves, I would do it repetitively in order to find the laws about how things react, and how they can be predicted. So from kicking leaves to Post-it notes to eventually reading about science, I constructed a map to navigate the world. Over time, it became bigger and notebooks piled up, so I ended up with a piece of work that I thought might be useful to someone else. And that’s the ultimate goal, isn’t it? You want to connect with people.

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Coronavirus live news: hospitals in England could be overwhelmed without new tiers, says Gove; social gathering banned in Los Angeles

The chief executive of NHS Providers has urged the government to “take precautions now” to ensure hospitals are not overwhelmed in January, which is the busiest time of the year for the healthcare service.

Chris Hopson said that “winter emergencies” like slipping on ice and breaking bones caused massive demand on the NHS in January, and that if there is “a cold snap, there will be a danger that the NHS gets overwhelmed.”

Every hospital in England could be overwhelmed with coronavirus cases if new tier restrictions are not introduced, cabinet minister Michael Gove has warned.

Gove said the decision to impose the restrictions was necessary to “pull the handbrake” and avoid the “disaster” of NHS hospitals reaching capacity with coronavirus patients.

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Extremely vulnerable in UK given high priority for coronavirus vaccine

Those with conditions such as blood, bone or lung cancer put in same category on interim guidance list as over-70s

People at very high risk of contracting coronavirus due to health problems, who were made to shield during the pandemic, have been given the same priority as the over-70s to receive a Covid-19 vaccine.

People aged 18 or older deemed “clinically extremely vulnerable” are in the same priority group as those aged 70 and over, according to the provisional vaccine priority list published by Public Health England.

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Denmark could dig up and cremate mink killed in Covid cull

Fears nitrogen and phosphorus could be released in large quantities into soil at grave sites

Denmark’s government is considering exhuming and cremating the remains of millions of culled mink after decaying carcasses started to emerge from a hastily dug grave.

After a mutated version of Covid-19 was found in the animals, the prime minister, Mette Frederiksen, announced a cull in early November of the estimated 15-17 million mink in Denmark, the world’s biggest exporter of mink fur.

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Coronavirus live news: North Korea ‘tried to hack’ South’s vaccine; Germany cases pass 1m

South Korea claims to have foiled North Korean hack attempt; Germany records 22,806 new cases to go past 1m in total; Russia reports new record cases high

Russia will ship some doses of its Sputnik V trial vaccine to Hungary next week, after a visit by a team of Hungarian doctors to see the manufacturing process, Reuters reports, citing a statement by the Russian health minister, Mikhail Murashko.

Hungary’s foreign minister, Peter Szijjarto, said talks were also underway on how the Russian vaccine could be potentially produced in Hungary.

Concerns around the efficacy of the Oxford University/AstraZeneca coronavirus jab in older people could lead to different age groups being given different vaccines, writes Nicola Davis, the Guardian’s science correspondent.

The partners announced last week that the vaccine had a 70% efficacy overall. For most trial participants – given two full doses, spaced a month apart – the efficacy was 62%, but for 3,000 participants mistakenly given half a dose for their first jab, the efficacy was 90%. No participants, regardless of dosing, developed severe Covid or were hospitalised with the disease.

Related: Different age groups may get different Covid vaccines, experts say

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Different age groups may get different Covid vaccines, experts say

Oxford/AstraZeneca planning new trial of lower-dose jab to see how well it works in older people

Concerns around the efficacy of the Oxford University/AstraZeneca coronavirus jab in older people could lead to different age groups being given different vaccines, experts have said.

The partners announced last week that the vaccine had a 70% efficacy overall. For most trial participants – given two full doses, spaced a month apart – the efficacy was 62%, but for 3,000 participants mistakenly given half a dose for their first jab, the efficacy was 90%. No participants, regardless of dosing, developed severe Covid or were hospitalised with the disease.

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