Hopes of Covid vaccine for more than 1bn people by end of 2021

Moderna becomes second firm to reveal positive results with nearly 95% protection in trials

More than 1 billion people could be immunised against coronavirus by the end of next year with shots from the first two companies to reveal positive results, after the latest vaccine was shown to be nearly 95% effective in trials.

With the US’s top infectious diseases official, Anthony Fauci, hailing “the light at the end of the tunnel”, the US biotech firm Moderna announced impressive results for its mRNA vaccine on Monday, a week after interim results for a Pfizer/BioNTech vaccine showed 90% effectiveness.

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Moderna vaccine’s effectiveness bodes well for Oxford/AstraZeneca jab

Phase 3 success rate of 95% for US firm’s treatment is promising for UK vaccine trial

Hopes are rising for the Covid jab being developed by Oxford University, after Moderna became the second company to reveal impressive results from its vaccine trials.

Interim results from phase 3 clinical trials of the Covid vaccine from US company Moderna has revealed it to be almost 95% effective at preventing the disease. The news followed an announcement last week from Germany-based Pfizer and BioNTech that their vaccine was more than 90% effective.

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Latest vaccine success is good news but high price may restrict access

Moderna results show Pfizer success was not flash in the pan, but poorer countries may have to look elsewhere

The success of Moderna’s vaccine against Covid-19 is reason for the whole world to cheer. The results from an interim analysis of the trial data are remarkably similar to those of Pfizer/BioNTech a week ago. Most people – Moderna says 94.5% in its trial, Pfizer said more than 90% – were protected from illness.

It’s fantastic news. It means the concept works. Pfizer’s results were not a flash in the pan. Both vaccines have been developed using a new technology that has never produced a licensed vaccine before, called messenger RNA (mRNA), which some hail as the future of all vaccines. It has the potential to deliver vaccines for all sorts of diseases cheaply and safely, enthusiasts say. And, crucially for the time being, they are likely to help us out of the Covid pandemic.

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What does the Moderna vaccine mean for the fight against Covid?

How does it work and how is it different from the Pfizer/BioNTech jab?

As promising results are released from a second vaccine trial, we take a look at what this could mean in the battle against Covid-19.

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Coronavirus live news: Japan may reimpose state of emergency; Sweden limits public gatherings to eight people

Moderna is latest to reveal impressive vaccine results; Sweden cuts public gatherings limit from 300 as it blames fall in adherence to rules

South Africa has recorded 1,245 new coronavirus cases and 73 further deaths.

The caseload stands at 752,269 , while 20,314 people have died.

#COVID19 Statistics in SA as at 16 November.

Use the COVID Alert SA app to protect yourself, your loved ones and your community. Start using this privacy preserving app today. Add your phone to the fight! Download the Covid Alert SA app now! https://t.co/8YKEqaiiRF pic.twitter.com/MwMJovMXA9

The Australian state of Victoria has recorded its 18th day without a new coronavirus case or death.

Yesterday there were 0 new cases, 0 lives lost. Three active cases remain, 0 with an unknown source. #EveryTestHelps and thanks to all who were tested, there were 17,412 results received. https://t.co/pcll7ySEgz#StaySafeStayOpen #COVID19Vic pic.twitter.com/k0HwjYcBrE

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Coronavirus live news: Russia and Iran report worst daily increase; Merkel to push for tougher curbs in Germany

Russia confirms over 22,000 new cases; Iran sees 13,053 new cases; German chancellor wants masks in all schools and more contact restrictions

We have more from Reuters on the tough new measures expected to be agreed in Germany, in a meeting between state leaders and the chancellor, Angela Merkel, later on Monday.

Earlier we reported how they would include compulsory mask-wearing at schools and drastic restrictions on household gatherings. A draft document of the measures, seen by Reuters, also said people would be urged to avoid private parties completely in coming weeks.

Hullo! This is Damien Gayle taking the reins on the live blog now for the rest of the working day here in the UK.

If you have any interesting coronavirus-related news, suggestions or comments from your part of the world, that you think is worth our including on the blog, please drop me a line, either via email to damien.gayle@theguardian.com, or via Twitter DM to @damiengayle.

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Covid: Boris Johnson and Tory MPs forced to self-isolate after No 10 event

PM says he is in good health and has no coronavirus symptoms ahead of crucial week

A string of Conservative MPs are self-isolating following a meeting inside Downing Street that has forced Boris Johnson to spend a potentially crucial political week holed up inside No 10.

The prime minister, who was seriously ill with coronavirus in April, has insisted he is fine and that his body “is bursting with antibodies” after being ordered to self-isolate following a meeting with northern Tory MPs on Thursday.

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Video gaming can benefit mental health, find Oxford academics

Research based on playing time data showed gamers reported greater wellbeing

Playing video games can be good for your mental health, a study from Oxford University has suggested, following a breakthrough collaboration in which academics at the university worked with actual gameplay data for the first time.

The study, which focused on players of Nintendo’s springtime craze Animal Crossing, as well as EA’s shooter Plants vs. Zombies: Battle for Neighborville, found that people who played more games tended to report greater “wellbeing”, casting further doubt on reports that video gaming can harm mental health.

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SpaceX Nasa launch: astronauts head to International Space Station onboard Dragon capsule

Mike Hopkins, Shannon Walker, Victor Glover and Japan’s Soichi Noguchi successfully lifted off for the 27-hour flight on Sunday

SpaceX has launched four astronauts to the International Space Station on the first full-fledged taxi flight for Nasa by a private company.

The Falcon rocket thundered into the night from Kennedy Space Center in Florida with three Americans and one Japanese onboard, the second crew to be launched by SpaceX. The Dragon capsule on top – named Resilience by its crew in light of this year’s many challenges, most notably Covid-19 – is due to reach the space station after 27-and-a-half hours and remain there until spring.

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Damage to multiple organs recorded in ‘long Covid’ cases

Exclusive: study of low-risk individuals finds impairments four months after infection

Young and previously healthy people with ongoing symptoms of Covid-19 are showing signs of damage to multiple organs four months after the initial infection, a study suggests.

The findings are a step towards unpicking the physical underpinnings and developing treatments for some of the strange and extensive symptoms experienced by people with “long Covid”, which is thought to affect more than 60,000 people in the UK. Fatigue, brain fog, breathlessness and pain are among the most frequently reported effects.

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Sage expert:’flip-flopping’ on Covid restrictions unwise

Prof John Edmunds calls for consistent UK government strategy and warns against relaxing measures

Encouraging the public to visit bars and restaurants and then closing down such venues when Covid-19 cases spike is not a “sensible way to run the epidemic”, a government scientific adviser has said.

Prof John Edmunds, a member of the Scientific Advisory Group for Emergencies (Sage), urged a long-term strategy when it comes to balancing the economy and the pandemic.

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Coronavirus live news: UK records 26,860 more cases and 462 deaths; US sees record 184,000 new daily cases

Italy has registered 37,255 new coronavirus infections over the past 24 hours, the health ministry announced on Saturday, down from 40,902 on Friday.

The ministry also recorded 544 Covid-related deaths, down from 550 the day before, Reuters reports.

Sixteen people have been arrested after hundreds of protestors attended an anti-lockdown demonstration in Liverpool city centre.

ARRESTS | 25 people have now been arrested in #Liverpool city centre for public order offences and breaches of Coronavirus regulations. A further male has been arrested after a police officer was assaulted. Please read our statement about why it's so important people stay home: pic.twitter.com/XcLXXLpuPH

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When rearranging a drawer is restful: the magic of ‘pottering’

How small tasks can benefit our state of mind

For Anna McGovern there is a satisfying, sensory pleasure to be had in rinsing milk bottles: “The very best thing about getting your milk delivered is ‘rinsing and returning’. Don’t cheat by putting your bottles in the dishwasher. Wash them, by hand. Put a small amount of water in the bottle, slosh the water around, put your hand over the top, shake it up and down, upturn the bottle, glugging the water out, then head for your doorstep and put out the bottle with a ‘plink’”.

This is one of many meandering, seemingly mundane tasks that McGovern delights in describing in her new book. Another is pegging out the washing (“Pull it out of the basket in a long, sweet-smelling, damp lump.”) In fact, when we speak about pottering, McGovern tells me she has done just that to “help order her thoughts”.

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New museum in Nigeria raises hopes of resolution to Benin bronzes dispute

Artefacts held by British Museum and other western institutions were looted by British forces in 1897

A new museum designed by Sir David Adjaye is to be built following the most extensive archaeological excavation ever undertaken in Benin City, Nigeria, raising hopes of a resolution to one of the world’s most controversial debates over looted museum artefacts.

The kingdom of Benin, in what is now southern Nigeria and not to be confused with the modern-day country of Benin, was one of the most important and powerful pre-colonial states of west Africa.

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SpaceX delays Crew Dragon launch due to poor weather

Forecasts of gusty, onshore winds over Florida force reschedule to Sunday of first full mission carrying four astronauts

Nasa and SpaceX have announced a 24-hour weather delay of their planned launch of four astronauts into orbit for America’s first fully fledged human mission using a privately owned spacecraft.

The liftoff time slipped from Saturday to Sunday evening due to forecasts of gusty, onshore winds over Florida – remnants of storm Eta – that would have jeopardised a return landing for the Falcon 9 rocket’s reusable booster stage, Nasa officials said.

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Leaders at a loss as coronavirus catches up with central Europe

Politicians struggle to explain why a region so much less affected in spring is so badly hit now

In the countries of central Europe, which during spring seemed to provide a best-practice model for keeping coronavirus at bay, case numbers have risen sharply, and governments in the region fear that their health systems are close to capacity and may struggle to cope. Central Europe is now just as badly hit as countries further west, and by some parameters is doing worse.

The Visegrad Four group of nations – Czech Republic, Poland, Hungary and Slovakia – were all notable for their success in keeping case numbers low earlier in the year, even as gruesome statistics of deaths and hospitalisations came out of western Europe on a daily basis.

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Coronavirus live news: Italy registers 550 more deaths; record daily cases in Germany, Sweden and Russia

Italy also registers 40,000 new infections; Germany records 23,542 new cases; Russia reports its worst day for new infections; Sweden’s hits daily record

Health authorities in the Australian state of NSW have released a list of three key “venues of concern” in Auckland as they check arrivals from New Zealand since 5 November.

•A-Z Collection, Auckland CBD: 10.30am-6.30pm on 8 November, 10.30am-6.30pm on 9 November, or 10.30am-6.30pm 11 November
•The Vincent Residences, Auckland Central: 12am on 7 November to 12pm 12 November
•Red Pig Restaurant, Auckland CBD: 6-8.30pm on 7 November

NSW Health is contacting 455 people who have arrived from New Zealand since 5 November following a locally acquired case of COVID 19 in Auckland. These passengers have been sent a message alerting them to a number of venues of concern in Auckland. pic.twitter.com/Gpd6avauBJ

News agency Reuters is reporting the latest case numbers from Brazil, one of the world’s worst-hit countries.

The country’s health ministry has reported 29,070 new Covid-19 cases and a further 456 deaths from the disease.

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Covid test for mass UK screening could miss up to half of cases, say scientists

Some trials of lateral flow test from US firm Innova found it was much less accurate than the government said it was

The lateral flow test bought by the UK government for mass testing in Liverpool, and potentially the whole country, could miss up to half of those who have Covid-19, according to experts.

The government has great expectations of the Innova test, having signed two contracts with the California-based company behind it. Innova told the Guardian it was now shipping more than one million tests a day to the UK.

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Coronavirus live news: Italy deaths highest since 6 April; France lockdown to last at least two more weeks

Italy registers 636 daily deaths; French PM says no easing of restrictions as cases remain high; Germany seeing tentative signs of flattening curve

Greece reported 3,316 new coronavirus cases on Thursday, its highest daily tally since its first infection surfaced in February, according to health authorities data.

The latest jump in infections brings the total number of cases in the country to 66,637.

Donald Trump’s adviser Corey Lewandowski has become the latest member of the outgoing president’s staff to test positive for coronavirus.

Lewandowski recently traveled to Pennsylvania to assist Trump’s efforts to contest the state’s election results. He said today he believes he was infected in Philadelphia and is not experiencing any symptoms.

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Scientist behind BioNTech/Pfizer vaccine says it can end pandemic

Exclusive: BioNTech’s CEO Uğur Şahin says he is confident vaccine can ‘bash the virus over the head’

The scientist behind the first Covid-19 vaccine to clear interim clinical trials says he is confident his product can “bash the virus over the head” and put an end to the pandemic that has held the world hostage in 2020.

The German company BioNTech and the US pharmaceutical giant Pfizer announced via a press release on Monday that their jointly developed vaccine candidate had outperformed expectations in the crucial phase 3 trials, proving 90% effective in stopping people from falling ill.

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