Nasa’s Parker Solar Probe beams back first insights from sun’s edge

Flying closer than any other mission, spacecraft set to unravel the sun’s mysteries

Nasa’s Parker Solar Probe, which has flown closer to the sun than any spacecraft, has beamed back its first observations from the edge of the sun’s scorching atmosphere.

The first tranche of data offers clues to long-standing mysteries, including why the sun’s atmosphere, known as the corona, is hundreds of times hotter than its surface, as well as the precise origins of the solar wind.

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China gene-edited baby experiment ‘may have created unintended mutations’

He Jiankui’s original research, published for the first time, could have failed, scientists say

The gene editing performed on Chinese twins to immunise them against HIV may have failed and created unintended mutations, scientists have said after the original research was made public for the first time.

Excerpts from the manuscript were released by the MIT Technology Review to show how Chinese biophysicist He Jiankui ignored ethical and scientific norms in creating the twins Lula and Nana, whose birth in late 2018 sent shockwaves through the scientific world.

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Mosquitoes bring ‘mystery illness’ to the mountain villages of Nepal

Rising temperatures linked to outbreaks of dengue fever high in the Kathmandu Valley, experts say

Global heating behind record number of cases of the disease

Lilawati Awasthi is used to the risks that come from living in a remote mountainous district in the far west of Nepal. Floods, landslides and treacherous roads are a part of daily life. But this year she faced a new hazard: mosquitoes carrying a mystery illness.

When she began to feel sick in September she was not overly concerned at first. “I thought it was a simple fever, but it wouldn’t go away,” says the 50-year-old. “We went to the hospital and it turned out I was suffering from dengue.”

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India’s crashed Vikram moon lander spotted on lunar surface

Nasa satellite sends back images showing wreckage of Chandrayaan-2 mission, with debris found scattered nearly a kilometre away

A Nasa satellite orbiting the moon has found India’s Vikram lander, which crashed on the lunar surface in September, the US space agency said on Monday.

Nasa released an image taken by its Lunar Reconnaissance Orbiter (LRO) that showed the site of the spacecraft’s impact and associated debris field, with parts scattered over almost two dozen locations spanning several kilometres.

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Half of all homeless people may have had traumatic brain injury

Experts say TBI could be consequence or cause of homelessness

Half of all homeless people may have suffered a traumatic brain injury at some point in their life, according to new research – which experts say could be either a consequence or even the cause of their homelessness.

Traumatic brain injury is sudden damage caused by a blow or jolt to the head, which can be caused by a motor accident, a fall or an assault. Sometimes it can cause long-term damage to the brain, leading to neurological and psychiatric disorders.

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Boris Johnson urged to challenge Trump on climate denial

350 experts call on PM to address president’s ‘dangerous’ and ‘irresponsible’ claims

Boris Johnson is being urged by 350 leading climate researchers to robustly challenge Donald Trump on his “dangerous” and “irresponsible” denial of the risks of climate change during the US president’s visit to the UK this week.

Putting the prime minister under more pressure over his stance on global heating, leading academics involved in climate research said he must try to persuade Trump to take strong domestic and international action.

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COP25: Island states want ‘decisive’ climate action to prevent inundation

The impact of rising seas prompts plea ahead of the UN climate change conference that begins on Monday in Madrid

The countries most at risk of deluge from climate chaos have issued an impassioned plea to the industrialised world ahead of crucial negotiations on the Paris agreement that start on Monday in Madrid.

“We see [these talks] as the last opportunity to take decisive action,” Janine Felson, deputy chair of the Alliance of Small Island States (AOSIS) told the Guardian.

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‘Pilates-changed-my-life’ stories are annoying… but it did

Over three years the exercise regime took Rachel Cooke from terrible back pain to new levels of fitness. But it was a lot harder than she expected

One morning almost five years ago, I awoke from uneasy dreams and, like Gregor Samsa in Franz Kafka’s story, The Metamorphosis, found myself to be… well, not precisely an insect, but the effect was similar. Trying to get out of bed, I realised I could barely move. So excruciating was the pain in my back, my only option seemed to be to roll myself – thunk! – on to the floor.

Lying there on my stomach for a few moments, I took in the view (beneath the bed were old shoes and dust balls the size of planets) and then, screwing up my courage, I crawled on to the landing – which is where I stayed for the rest of the day, sobbing quietly and wondering how I would get to the loo; when, exactly, the NHS emergency doctor would arrive.

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Bad luck may have caused Neanderthals’ extinction – study

Homo sapien invasion may not have prompted Neanderthals’ demise 40,000 years ago

Perhaps it wasn’t our fault after all: research into the demise of the Neanderthals has found that rather than being outsmarted by Homo sapiens, our burly, thick-browed cousins may have gone extinct through bad luck alone.

The Neanderthal population was so small at the time modern humans arrived in Europe and the Near East that inbreeding and natural fluctuations in birth rates death rates and sex ratios could have finished them off, the scientists claim.

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Climate emergency: world ‘may have crossed tipping points’

Warning of ‘existential threat to civilisation’ as impacts lead to cascade of unstoppable events

The world may already have crossed a series of climate tipping points, according to a stark warning from scientists. This risk is “an existential threat to civilisation”, they say, meaning “we are in a state of planetary emergency”.

Tipping points are reached when particular impacts of global heating become unstoppable, such as the runaway loss of ice sheets or forests. In the past, extreme heating of 5C was thought necessary to pass tipping points, but the latest evidence suggests this could happen between 1C and 2C.

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Mystery sounds from storms could help predict tornadoes

Scientists narrow down causes of low-frequency rumbles emitted before twisters form

Mysterious rumbles that herald tornadoes could one day be used to predict when and where they will strike, according to researchers.

Storms emit sounds before tornadoes form, but the signals at less than 20Hz are below the limit for human hearing. What causes these rumbles has also been a conundrum.

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Daring Mars mission to send rocks back to Earth in hunt for past life

Europe poised to join US in complex plan to find evidence of fossil microbes on red planet

Engineers plan to collect rocks on Mars and bring samples to Earth, in one of the most complex robot space projects envisaged. The scheme, being developed by Nasa and the European Space Agency (Esa), will involve robot rovers finding rocks that might contain evidence of past life.

The samples would be blasted into space, intercepted by an unmanned spacecraft, and dropped by parachute in the Utah desert, with the 500g of Martian soil and rock shared with researchers round the world.

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Humans put into suspended animation for first time

Groundbreaking trial in US rapidly cools trauma victims with catastrophic injury to buy more time for surgery

Doctors have put humans into a state of suspended animation for the first time in a groundbreaking trial that aims to buy more time for surgeons to save seriously injured patients.

The process involves rapidly cooling the brain to less than 10C by replacing the patient’s blood with ice-cold saline solution. Typically the solution is pumped directly into the aorta, the main artery that carries blood away from the heart to the rest of the body.

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Global heating supercharging Indian Ocean climate system

Indian Ocean dipole events, linked to bushfires and floods, are becoming stronger and more frequent, scientists say

Global heating is “supercharging” an increasingly dangerous climate mechanism in the Indian Ocean that has played a role in disasters this year including bushfires in Australia and floods in Africa.

Scientists and humanitarian officials say this year’s record Indian Ocean dipole, as the phenomenon is known, threatens to reappear more regularly and in a more extreme form as sea surface temperatures rise.

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Scientists develop slippery toilet coating to stop poo sticking

Spray-on surface could prevent bacteria building up and reduce household water use

The toilet brush need never leave its holder again. Scientists have created a super-slippery coating that helps usher excrement on its way without leaving traces behind.

The spray-on coating, which is slipperier than Teflon, reduces adhesion of even tenacious faeces by up to 90%, tests suggest, so far less water is needed to flush them away and leave the toilet clean.

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A psychedelic retreat proves a healing trip

Exploring the therapeutic benefits of magic mushrooms at a ceremony in Amsterdam

I’m at a weekend retreat in a converted church near Amsterdam. There is soft, celestial music playing and I’m sipping fresh herbal tea while discussing my hopes and fears for tomorrow’s “ceremony”, which is retreat parlance for a psychedelic trip. Consuming the truffle parts of magic mushrooms is permitted in the Netherlands and my nine fellow guests and I will be eating a variety called Dragon’s Dynamite. We’re not taking recreational drugs, but rather using psychedelics as self-exploratory and therapeutic “plant medicine”. Welcome to the age of the psychedelic retreat.

Synthesis opened its doors in April 2018. It was co-founded by Martijn Schirp, a former poker player who found salvation through psychedelics. “I had my first mushroom trip nine years ago and that changed my life,” he says. “I was walking through this forest and it was so peaceful, it was like a fairy tale. I felt this huge self-critical voice lift off me.” He believes he’d still be estranged from his father if it wasn’t for the perspective psychedelics have given him. His entrepreneurial mind saw that what was missing was a retreat with “medical supervision, private one-to-one coaching and professional standards in a modern context”.

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Rabies breakthrough offers fresh hope in battle against deadly virus

New research raises hopes of oral vaccine for dogs, the chief source of transmission to humans

Researchers have discovered a way to stop rabies from shutting down critical responses in the immune system, a breakthrough that could pave the way for new tools to fight the deadly disease.

Rabies kills almost 60,000 people each year, mostly affecting poor and rural communities.

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Who’s the daddy? Paternity mixed up in cities, study finds

Illegitimacy more likely over past 500 years among urban poor, say geneticists

The Romans had a phrase that summed it up nicely: mater semper certa est, pater semper incertus est. The mother is always certain, the father is always uncertain.

Now, researchers have found that some people have more reason to doubt their fathers than others, or at least have had over the past half millennium.

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Climate change may be behind fall of ancient empire, say researchers

Dramatic shift from wet to dry climate could have caused crop failure in Neo-Assyrian empire

The Neo-Assyrian empire was a mighty superpower that dominated the near east for 300 years before its dramatic collapse. Now researchers say they have a novel theory for what was behind its rise and fall: climate change.

The empire emerged in about 912BC and grew to stretch from the Mediterranean down to Egypt and out to the Persian Gulf.

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Two people diagnosed with pneumonic plague in China

Authorities working to contain outbreak of disease that is worse than bubonic plague

Two people in China have been diagnosed with plague, the latest cases of a disease more commonly associated with historical catastrophe.

Plague is caused by the bacterium Yersinia pestis and can arise in three forms – a lung infection, known as pneumonic plague; a blood infection, known as septicemic plague; and a form that affects the lymph nodes, called bubonic plague.

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