Astronomers spot ‘overweight’ planet that appears too big for tiny host star

Fact that planet 13 times bigger than Earth is orbiting star nine times smaller than sun shows ‘how little we know about the universe’

Astronomers have spotted an “overweight” planet that appears to be far too massive for its petite host star.

The planet, which is 13 times bigger than Earth, is orbiting a star called LHS 3154, which is nine times smaller than the sun. The planet’s heft is unremarkable in its own right, but its pairing with an ultracool dwarf star, the smallest and coldest stars in the universe, has puzzled scientists.

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Matt Hancock ‘was not told about eat out to help out scheme until day it was announced’ – as it happened

This live blog is now closed, you can read more on this story here

Hancock is now deploying the defence previewed in the Observer on Sunday. (See 9.58am.)

He says from the middle of January the DHSC was “trying to effectively raise the alarm”. He says:

We were trying to wake up Whitehall to the scale of the problem and this wasn’t a problem that couldn’t be addressed only from the health department. Non-pharmaceutical interventions cannot be put in place by a health department. A health department can’t shut schools. It should have been grasped and led from the centre of government earlier. And you’ve seen evidence that repeatedly the department and I tried to make this happen.

And we were on occasions blocked, and at other times our concerns were not taken as seriously as they should have been until the very end of February.

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Genetic data on 500,000 volunteers in UK to be released for scientific study

UK BioBank offers up biggest ever cache of whole-genome sequences for medical research

A new era of medical discoveries, treatments and cures is on the horizon, researchers say, following the announcement that an unprecedented trove of genetic information is to be made available to scientists.

Health researchers from around the world can now apply to study the whole genomes of half a million people enrolled in UK Biobank, a biomedical research project that has compiled detailed health and lifestyle records on individuals since it began 20 years ago.

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UK Biobank and the masses of medical data that became key to genetic research

The resource, which is on the move to Manchester, now ranks as the world’s most important health database

The origins of the UK Biobank can be traced back to a pilot study in a building in Stockport bordered by the Cheadle Heath police station on one side and the local recreation ground on the other. It was the early 2000s and scientists had realised the potential for genomics and big data to transform health research.

With diabetes, cancer, dementia and other ailments on the rise, scientists pushed for a database devoted to genetics, health and lifestyle to help them tease apart who was most at risk and how diseases could be prevented.

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‘A biodiversity catastrophe’: how the world could look in 2050 – unless we act now

The climate crisis, invasive species, overexploitation of resources and pollution could break down crucial ecosystems. We asked experts to lay out the risks and offer some solutions

The continued destruction of nature across the planet will result in major shocks to food supplies and safe water, the disappearance of unique species and the loss of landscapes central to human culture and leisure by the middle of this century, experts have warned.

By 2050, if humanity does not follow through on commitments to tackle the five main drivers of nature loss critical natural systems could break down just as the human population is projected to peak.

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‘They thought I had cancer’: painkiller banned in UK linked to Britons’ deaths in Spain

Patients’ group says reactions to metamizole can cause sepsis and organ failure – and British and Irish people are at higher risk

A patients group representing several British victims has launched legal action against the Spanish government over claims it failed to safeguard people against the potentially fatal side effects of one of the country’s most popular painkillers, involved in a series of serious illnesses and deaths.

The drug metamizole, commonly sold in Spain under the brand name Nolotil, is banned in several countries, including Britain, the US, India and Australia. It can cause a condition known as agranulocytosis, which reduces white blood cells, increasing the risk of potentially fatal infection.

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Bone cows bred in Australia provide base material for dental grafts

Use of cattle from country free of mad cow disease means product is safe, experts say, and patients can still donate blood

Bone cows, specially bred in mad cow-free Australia, are being used instead of human donors for dental and medical bone grafts.

While bovine grafts have been tested for spinal fusion, foot reconstructions and to fix skull traumas, the Australian versions are predominantly used in dental work to strengthen degraded jaws before tooth implants.

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China supplies data to WHO about clusters of respiratory illness

Epidemiologists say wave in north, particularly among children, may be partly caused by ‘immunity debt’

Chinese health authorities have provided the requested data on an increase in respiratory illnesses and reported clusters of pneumonia in children, and have not detected any unusual or novel pathogens, the World Health Organization (WHO) said on Thursday.

The WHO had asked China for more information on Wednesday after groups including the Program for Monitoring Emerging Diseases reported clusters of undiagnosed pneumonia in children in north China.

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OpenAI ‘was working on advanced model so powerful it alarmed staff’

Reports say new model Q* fuelled safety fears, with workers airing their concerns to the board before CEO Sam Altman’s sacking

OpenAI was reportedly working on an advanced system before Sam Altman’s sacking that was so powerful it caused safety concerns among staff at the company.

The artificial intelligence model triggered such alarm with some OpenAI researchers that they wrote to the board of directors before Altman’s dismissal warning it could threaten humanity, Reuters reported.

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Cheap over-the-counter nail drug found to work on crippling flesh-eating disease

‘Momentous’ breakthrough as trial finds treatment for nail infections to be highly effective for neglected tropical disease

A cheap and easily taken drug used to treat fungal nail infections has been found to work against a devastating flesh and bone-eating disease found across Africa, Asia and the Americas.

Researchers say the breakthrough offers hope to thousands of patients who have suffered decades of neglect and can face amputations if the disease is left untreated.

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Scientists raise hopes of cure for eczema itchiness with study of skin bacteria

Researchers say they have discovered a common type of bacteria can trigger irritation

Whether it’s a tickle of the nose, or an irritation in one’s hair, itches can be excruciating. Now scientists say they have found a common type of skin bacteria can trigger the sensation.

Crucially, as such bacteria are commonly found on the skin of patients with eczema – or atopic dermatitis – the work helps explain why such conditions can be accompanied by the urge to scratch.

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Chris Whitty says No 10 decision-making ‘chaotic’ under Boris Johnson but other countries were similar – UK Covid inquiry live

Chief medical officer for England and chief UK medical adviser says civil servants did good job but PM took ‘unique’ decisions

Q: Was there no aspect on the pandemic on which you did not advise?

Whitty says he would not put it like that. He says he felt it important to advise on issues where advice from a scientist or doctor would be useful.

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Boris Johnson ‘bamboozled’ by science and Matt Hancock had habit of saying things that were untrue, UK Covid inquiry hears – live

Former chief scientific adviser Patrick Vallance revealed there was ‘complete lack of leadership’ at times in crisis

Vallance says that some of what he was doing during Covid would have been done by anyone else in the post of government chief scientific adviser (GCSA).

But he says because of his medical training, and his knowledge of vaccines (he had worked for GlaxoSmithKline before taking the GCSA job), he was probably more involved than another GCSA might have been.

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Patrick Vallance contradicts Rishi Sunak’s evidence to Covid inquiry

PM would almost certainly have known concerns over ‘eat out to help out’ scheme, says former chief scientific adviser

Rishi Sunak would almost certainly have known scientists were worried about his “eat out to help out” scheme during the pandemic, Sir Patrick Vallance has said, directly contradicting the prime minister’s evidence to the Covid inquiry.

In potentially damaging testimony, Vallance, the UK government’s chief scientific adviser during the pandemic, said he would be “very surprised” if Sunak had not learned about objections to his plan to help the hospitality industry.

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UK needs more lab space if it wants to be science superpower, ministers told

Leading property firms also call for more tax breaks and improved transport links to hubs ahead of autumn statement

The UK needs to build more laboratory space, improve transport links and offer more tax breaks to achieve Rishi Sunak’s ambition of becoming a science superpower, two leading property firms have argued ahead of the autumn statement.

Demand for laboratories in the UK is growing fast, with lab vacancy rates of just 1% in Cambridge and London, and 7% in Oxford, according to a report by British Land, one of Britain’s biggest property developers, and the upmarket estate agency and advisory firm Savills.

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Nasa’s hunt for signs of life on Mars divides experts as mission costs rocket

The soaring price-tag of a plan to fly rock samples back to Earth is jeopardising other space projects, say critics

It is one of the most complex space missions ever contemplated. A flotilla of unmanned probes and robot rovers will be flown to Mars to gather rock samples which will then be blasted back to Earth for study for signs of life.

This is Nasa’s Mars Sample Return and it would involve the first-ever space launch from another planet, as well as the first-ever rendezvous in orbit around another planet.

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Tongue-twisters could be used to gauge alcohol-intoxication levels, study finds

Method could be used to stop people from unlocking cars or to support bartenders serving alcohol

Whether it is the story of Peter Piper and his pickled peppers or a woman selling sea shells on the seashore, tongue-twisters tackled when sober can sound rather different after a drink.

Now researchers believe such changes, in particular those relating to pitch and frequency, could be used to alert people to their level of intoxication.

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Simple blood tests for dementia to be trialled in NHS

£5m project launched with aim of having reliable tests within five years to provide quick diagnosis

Scientists are to begin piloting simple blood tests for dementia that could revolutionise detection of the disease and within five years lead to people being diagnosed in seconds by the NHS.

Currently, getting a formal diagnosis in the UK relies on mental ability tests, brain scans or invasive and painful lumbar punctures, where a sample of cerebrospinal fluid is drawn from the lower back.

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Drug that can halve breast cancer risk offered to 289,000 women in England

Anastrozole to be made available to women who have been through the menopause and have family history of breast cancer

Almost 300,000 women at higher risk of developing breast cancer are being given access to a drug that can halve their risk in a “major step forward” in the fight against the disease.

An estimated 289,000 women in England who are at moderate or high risk of breast cancer will from Tuesday be able to take the tablet to try to prevent it from developing, NHS bosses said.

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Large-scale warfare occurred in Europe ‘1,000 years earlier than previously thought’

Reanalysis of skeletal remains in Spain suggests conflicts took place about 5,000 years ago in neolithic period, say researchers

The earliest period of warfare in Europe might have occurred more than 1,000 years before what was previously thought to be the first large-scale conflict in the region, researchers have suggested.

Reanalysis of more than 300 sets of skeletal remains uncovered in Spain – radiocarbon dated to between 5,400 and 5,000 years ago – indicates that conflicts took place long before powerful states formed in the region.

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