Category Archives: Biology

Scientists’ egos are key barrier to progress, says Covid vaccine pioneer

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Prof Katalin Karikó of BioNTech says she endured decades of scepticism over her work on mRNA vaccines

Scientists would make swifter progress in solving the world’s problems if they learned to put their egos aside and collaborate better, according to the leading researcher behind the Pfizer/BioNTech Covid vaccine.

Prof Katalin Karikó, the senior vice-president for RNA protein replacement therapies at BioNTech in Germany, endured decades of scepticism over her work and was demoted and finally kicked out of her lab while developing the technology that made the Pfizer and Moderna vaccines possible.

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WHO monitoring new coronavirus variant named Mu

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Health body says Mu, or B.1.621, first identified in Colombia, has been designated as a variant of interest

The World Health Organization has added another version of coronavirus to its list of “variants of interest” amid concerns that it may partially evade the immunity people have developed from past infection or vaccination.

The Mu variant, also known as B.1.621, was added to the WHO’s watchlist on 30 August after it was detected in 39 countries and found to possess a cluster of mutations that may make it less susceptible to the immune protection many have acquired.

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Being a Human review – two go mad in the stone age

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Charles Foster’s search for the meaning of human life leads him and his son to become hedgehog-eating hunter-gatherers in a Derbyshire wood

Charles Foster’s previous book, Being a Beast, is one of the oddest things I’ve read. In it, the author, a barrister, professor of law, part-time judge and former vet, attempts to live as a series of animals, often in the company of his charming and heavily dyslexic eight-year-old son, Tom. We see Foster eating worms and burrowing into the earth as a badger, swimming naked as an otter, foraging in bins as a fox. Now Foster is back with a follow-up, Being a Human, which acknowledges the charges of eccentricity and even insanity that were levelled at the last book.

Foster’s new work continues the project of its predecessor, although this time, rather than seeking to understand the brains and bodies of animals, his question is closer to home: what does it mean to be human? He begins with a contentious argument: far from being a story of progress, the history of humanity is one of disenchantment and loss, one where we have severed our links with other species and the natural world more broadly and in which we live meagre, circumscribed lives. “Few of us have any idea what sort of creatures we are,” he says and embarks on a quest to find out.

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An oral history of Oxford/AstraZeneca: ‘Making a vaccine in a year is like landing a human on the moon’

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It has shipped more than a billion doses, saved countless lives – and faced controversy over its safety and supply. Here, some of those who created the vaccine tell the story of their epic race against the virus

In December 2019, hospitals in Wuhan, China, reported that they were dealing with dozens of cases of pneumonia of an unknown cause. They soon identified the disease as being caused by a novel coronavirus.

Teresa Lambe, associate professor, Jenner Institute My brother lived in China, so whenever there was an emerging or break pathogen there, I used to follow it. I remember thinking very early on that this was probably another influenza strain.

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UK scientists look at reducing boosters to save vaccine for rest of the world

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JCVI considers lower third jab dosage to release stocks for poorer nations

Scientists in Britain are examining whether smaller doses of Covid vaccine could be used as part of booster programmes, amid hopes that the approach could also increase the supply of jabs across the world.

The use of so-called “fractional doses” has been proposed as a way of ensuring that precious supplies can immunise as many people as possible in parts of the world where there are shortages, while still providing high levels of protection from the virus.

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The Wuhan lab leak theory is more about politics than science

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Whatever this week’s Biden review finds, the cause of the pandemic lies in the destruction of animal habitats

If Joe Biden’s security staff are up to the mark, a new report on the origins of the Covid-19 pandemic will be placed on the president’s desk this week. His team was given 90 days in May to review the virus’s origins after several US scientists indicated they were no longer certain about the source of Sars-CoV-2.

It will be intriguing to learn how Biden’s team answers the critically important questions that still surround the origins of Sars-CoV-2, the virus that causes Covid-19. Did it emerge because of natural viral spillovers from bats to another animal and then into humans? Or did it leak from the Wuhan Institute of Virology? And, if so, had it been enhanced to make it especially virulent?

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New Covid variants ‘will set us back a year’, experts warn UK government

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Vaccine-beating variant is ‘realistic possibility’, say scientists, amid calls for contingency plans to be revealed

Ministers are being pressed to reveal what contingency plans are in place to deal with a future Covid variant that evades current vaccines, amid warnings from scientific advisers that such an outcome could set the battle against the pandemic back a year or more.

Recent papers produced by the government’s Scientific Advisory Group for Emergencies (Sage) have suggested that the arrival of a variant that evades vaccines is a “realistic possibility”. Sage backed continued work on new vaccines that reduce infection and transmission more than current jabs, the creation of more vaccine-production facilities in the UK and lab-based studies to predict evolution of variants.

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Well-preserved 28,000-year-old lion cub found in Siberian permafrost

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Female cave lion cub named Sparta in Russia’s Yakutia region may even have traces of mother’s milk in it

Scientists have said that an astonishingly well-preserved cave lion cub found in Siberia’s permafrost lived 28,000 years ago and may even have traces of its mother’s milk in it.

The female cub, named Sparta, was found at the Semyuelyakh River in Russia’s Yakutia region in 2018 and a second lion cub called Boris was found the year before, according to a study published in the Quaternary journal.

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UK children aged 16 and 17 expected to be offered Covid vaccine

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Minister says JCVI experts to update advice ‘imminently’ on widening access to vaccine to more teenagers

Covid vaccines are expected to be offered to children in the UK aged 16 and 17, in line with many other countries, after a minister confirmed government experts will update their advice “imminently”.

Michelle Donelan, the universities minister, said the government was expecting an announcement from the Joint Committee on Vaccination and Immunisation (JCVI) on widening access to the coronavirus vaccine to more teenagers.

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The insect apocalypse: ‘Our world will grind to a halt without them’

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Insects have declined by 75% in the past 50 years – and the consequences may soon be catastrophic. Biologist Dave Goulson reveals the vital services they perform

I have been fascinated by insects all my life. One of my earliest memories is of finding, at the age of five or six, some stripy yellow-and-black caterpillars feeding on weeds in the school playground. I put them in my empty lunchbox, and took them home. Eventually they transformed into handsome magenta and black moths. This seemed like magic to me – and still does. I was hooked.

In pursuit of insects I have travelled the world, from the deserts of Patagonia to the icy peaks of Fjordland in New Zealand and the forested mountains of Bhutan. I have watched clouds of birdwing butterflies sipping minerals from the banks of a river in Borneo, and thousands of fireflies flashing in synchrony at night in the swamps of Thailand. At home in my garden in Sussex I have spent countless hours watching grasshoppers court a mate and see off rivals, earwigs tend their young, ants milk honeydew from aphids, and leaf-cutter bees snip leaves to line their nests.

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China refuses further inquiry into Covid-19 origins in Wuhan lab

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WHO proposal to audit Chinese laboratories is ‘arrogance towards science’, says health minister

China’s government has refused to cooperate with the second stage of an international investigation into the origins of Covid-19, labelling a proposal to audit Chinese labs as “arrogance towards science”.

Chinese health officials held a press conference on Thursday to respond to last week’s proposal by the World Health Organization that the second phase of its investigation into the origins of the pandemic include “audits of relevant laboratories and research institutions operating in the area of the initial human cases identified in December 2019”, meaning the city of Wuhan.

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Reasons to be fearful of China’s data-gathering | Letters

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We should be suspicious of the role of the Chinese Communist party in the harvesting of genetic data from unborn babies, argues William Matthews

In her column (What does the Chinese military want with your unborn baby’s genetic data?, 10 July), Arwa Mahdawi suggested that the alleged involvement of the People’s Liberation Army (which is directly answerable to the Chinese Communist party) with BGI’s data-gathering (likewise answerable as a China-based company) is essentially equivalent to data-gathering by western companies. To suggest that the former case is worse, she argued, “smacks of Sinophobia”.

As a scholar of China, I cannot agree. While the harvesting of genetic data by any company is frightening and fraught with ethical issues, it should be obvious that this is a false equivalence. It is undoubtedly worse if genetic data is gathered by a company which must also comply with the rule of the Chinese Communist party (CCP) and its military-industrial complex, a regime which harvests and aggregates data on its citizens on a massive scale and uses it directly to implement the most repressive system of social control on earth in Xinjiang.

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Health campaigners call for an end to the use of the word leper

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Derogatory use of the “L-word” has increased during Covid and is said to be further marginalising people with the curable disease

Health campaigners are calling for an end to the use of the word leper, saying the language frequently used by politicians and others during the pandemic has made people with leprosy even more marginalised.

The metaphor of the socially outcast “leper” has been used often, whether in media reports on stigma against early Covid-19 patients or by politicians in Italy and Brazil complaining about being seen as “leper colonies”. Campaigners now want an end to the use of what they call the “L-word”.

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Covid live: public in England expected to wear masks when measures lift; Indonesia reports 1,007 daily deaths

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UK minister says mask guidance indoors is set to stay in England; Indonesian death toll rises to total of 66,464 after deadly day

The Press Association have written up warnings expressed by Sir David Spiegelhalter on the BBC’s Andrew Marr Show today that life is likely to be “massively disrupted” by people being told to self-isolate as the number of coronavirus cases rises over the summer.

The statistician said it would make sense to get the rules “in proportion” today as vaccines minister Nadhim Zahawi confirmed the Government was looking at ways to tweak the NHS Covid app.

Few people told to self-isolate actually have an infection, and especially if they’re vaxxed, and so I do think it makes sense to get this in proportion to actually ‘what are the benefits of this massive disruption

The team are looking at how we use that app in terms of alerting people to those around them who test positive.

It’s important to look at that in a new context of this massive vaccination programme and make sure that it is fit for purpose for this new world including, for example, being able to take maybe five days, as we have piloted, of lateral flow tests and upload them to the system rather than having to self-isolate.

In Libya, Al-Wasat news is reporting that the country has recorded a record number of coronavirus cases.

The National Center for Disease Control announced the registration of 2,854 new cases of the “emerging corona virus”, in addition to 376 cases of recovery, and 8 deaths, in the highest number of infections since March 2020.

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Climate crisis causing male dragonflies to lose wing ‘bling’, study finds

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Black patterns used to attract mates can cause the insects to overheat in hotter climates

Male dragonflies are losing the “bling” wing decorations that they use to entice the females as climates get hotter, according to new research.

The results have led to the scientists calling for more work on whether this disparate evolution might lead to females no longer recognising males of their own species in the long run.

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‘Real’ T rex goes on show in England for first time in over a century

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The skeleton of Titus, discovered in the US in 2018, makes its world debut at Nottingham museum

The first ‘real’ Tyrannosaurus rex to be exhibited in England for more than a century will go on show in Nottingham on Sunday.

The skeleton of Titus, discovered in the US state of Montana in 2018, will make its world debut at the Wollaton Hall Natural History Museum as part of a new exhibition on the dinosaur’s life and environment.

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Covid: Sage scientist fears England could repeat ‘mistakes of last summer’

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Prof Stephen Reicher says restrictions may have to be reimposed if reopening leads to surge in infections

A scientific adviser to the government’s Covid-19 response has expressed fears England could be in danger of repeating “the mistakes of last summer”.

Prof Stephen Reicher, from the University of St Andrews and a member of the Scientific Advisory Group for Emergencies (Sage) subcommittee on behavioural science, said the government may have to reimpose restrictions if the reopening leads to a surge in infections.

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Mixing Covid vaccines offers strong immune protection – study

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Oxford researchers say having AstraZeneca then Pfizer jabs is almost as potent as two shots of Pfizer

Having different Covid vaccines for first and second shots produces a strong immune response to the virus, according to research that will help improve the resilience of vaccine programmes around the world.

Scientists in Oxford looked at the impact of a mix-and-match approach to vaccinations where people were given either the standard two shots of Oxford/AstraZeneca or Pfizer/BioNTech vaccine, or a combination of the two.

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Vaccine inequality: how rich countries cut Covid deaths as poorer fall behind

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Developed countries are seeing the benefits of quickly vaccinating their populations, but concerns remain about the unequal share of global vaccine supplies

New analysis by the Guardian has confirmed that a speedy Covid vaccination campaign pays off when it comes to escaping the worst of the pandemic.

As the chart below shows, countries such as Israel, the UK and the US have all seen deaths decline as vaccination coverage extended to the most vulnerable in their societies.

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Fossilised bones found in Israel could belong to mystery extinct humans

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Remains with combination of Neanderthal and early human features date back 100,000 years

Fossilised bones recovered from an ancient sinkhole in Israel may belong to a previously unknown group of extinct humans that lived in the Levant more than 100,000 years ago.

Researchers unearthed the bones alongside stone tools and the remains of horses, fallow deer and wild ox during excavations at the Nesher Ramla prehistoric site near the city of Ramla in central Israel.

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