Quantum leap for medical research as microscope zooms in on tiny structures

Australian scientists develop a microscope that works with 35% more clarity, raising hope for improvements in medical imaging

Australian researchers have developed a microscope that can image tiny biological structures that were previously not visible in what has been described as a significant step for quantum technology.

It is believed to be the first time that quantum technology has improved on existing light microscopes, which in future may lead to improvements in medical imaging and navigation systems.

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Leading biologist dampens his ‘smoking gun’ Covid lab leak theory

Nobel laureate David Baltimore says he overstated case, and the origins of the virus are still unknown

A Nobel prize-winning US biologist, who has been widely quoted describing a “smoking gun” to support the thesis that Covid-19 was genetically modified and escaped from a Wuhan lab, has said he overstated the case.

David Baltimore, a distinguished biology professor, had become one of the most prominent figures cited by proponents of the so-called lab leak theory.

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24,000-year-old organisms found frozen in Siberia can still reproduce

Russian scientists find bdelloid rotifers deep in remote permafrost

A microscopic worm-like creature, labelled an “evolutionary scandal” by biologists for having thrived for millions of years without having sex, has now been shown to persist for at least 24,000 years in Siberian permafrost and then reproduce, researchers have found.

Multicellular invertebrates that are solely female, bdelloid rotifers are already renowned for their resistance to radiation and ability to withstand rather inhospitable environments: drying, starvation and low oxygen. They’ve also existed for at least 35m years – and can be found today in freshwater lakes, ponds, streams and moist terrestrial habitats such as moss, lichen, tree bark and soil.

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Human challenge: the people volunteering to be infected with Covid

Amid claims PM wanted to be infected with Covid on TV, volunteers tell of taking part in a human challenge trial

If Dominic Cummings is to be believed, Boris Johnson was so sceptical that Covid-19 was a threat early last year that he was willing to inject himself with the virus that causes the disease on television. But there are actual volunteers – young and healthy people – who elected to be infected with the virus, all in the name of science.

These volunteers lined up to participate in “human challenge trials”, which have long been successfully employed to develop vaccines for diseases from typhoid to cholera.

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Coronavirus news: UK records another 3,398 cases and seven deaths; Italy reports fall in daily fatalities

Health experts urge caution on giving Covid vaccines to UK children; Victoria records five new cases of Covid-19 taking Melbourne outbreak to 35

Anti-vaccine protest in London descends into clashes between protesters and police.

Boris Johnson and the UK government are too busy “covering their own backs” to properly counter the threat posed by the Indian coronavirus variant, Labour leader Sir Keir Starmer claimed.

Following Dominic Cummings’ explosive evidence about the prime minister’s handling of the pandemic, Sir Keir said “mistakes are being repeated” as the government considers whether to further ease restrictions.

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Vietnam discovers new hybrid Covid variant, state media reports

Strain is a combination of UK and India variants and is said to spread quickly

Vietnam has discovered a new Covid-19 variant which spreads quickly by air and is a combination of variants first identified in India and the UK, state media has reported.

The country is struggling to deal with fresh outbreaks across more than half of its territory including industrial zones and big cities such as Hanoi and Ho Chi Minh City.

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Monkeys adopt ‘accent’ of other species when in shared territory – study

Brazilian Amazon primates found to adapt their calls to get along better with their neighbours

Monkeys will use the “accent” of another species when they enter its territory to enhance communication, much like a British person living in the US might forgo their ‘tomahto’ for ‘tomayto, researchers have found.

Researchers investigated the behaviour of 15 groups of two roughly squirrel-sized primate species in the Brazilian Amazon: pied tamarins (Saguinus bicolor) and red-handed tamarins (Saguinus midas).

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Coronavirus live news: Britain records 2,694 new Covid cases; Dominic Cummings criticises government over lockdowns

Germany to bar visitors from UK over Covid variants of concern; sewage samples being tested across England to monitor Covid variants

Australia has now administered more than 3.5m doses of a Covid-19 vaccine, with a further 89,000 jabs delivered around the country.

New South Wales delivered 12,485 doses in the past 24 hours, becoming another one-day record for the state. Around 5000 of them were administered at its Olympic Park mass vaccination hub alone, AAP reports.

Malaysia has reported a further 6,320 coronavirus cases amid a recent surge in infections, as well as 50 new deaths. Saturday’s figures compare with 4,140 cases and 44 deaths a week today.

The nation reported a record high of 6,806 new cases on Thursday when it also saw its highest daily toll of 59 deaths. Taking the total number of cases since the onset of the pandemic to 505,115, Reuters reports.

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Pfizer and AstraZeneca ‘highly effective’ against India Covid variant

A Public Health England study has revealed the vaccines can be up to 88% effective after a second dose

Both the Pfizer and AstraZeneca jabs are highly effective at protecting people from the strain of the Covid-19 virus first found in India, a study by Public Health England (PHE) has found.

The analysis, carried out between 5 April and 16 May, found the Pfizer vaccine was 88% effective against symptomatic disease from the India variant two weeks after a second dose, compared with 93% effectiveness against the Kent strain. For its part, the AstraZeneca jab was 60% effective, compared with 66% against the Kent variant over the same period.

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India variant could lead to serious third wave of Covid in UK

Analysis: If B.1.617.2 proves highly transmissible, hospitalisations could peak again, models show

It was all looking so good. After a brutal second wave in the winter, the lockdown combined with the swift rollout of vaccines forced infections, hospitalisations and deaths down to levels not seen since last summer. The vaccines performed better than expected, not only in preventing deaths, but in hampering the spread of the virus. Scientific advisers were confident about England’s cautious roadmap back to a life more normal: the worst, it seemed, was over.

Now, those same advisers are deeply worried that the new variant of concern from India, B.1.617.2, could undermine the hard-won achievement. The government strategy has been to ease restrictions as vaccines reach more people, aiming for a delicate balance that opens up society while preventing another wave that overwhelms the NHS.

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Indian Covid variant: which countries have highest infection rates?

Some data suggests variant has ‘increased transmissibility’ compared with other strains

The World Health Organization said on Tuesday the Indian Covid-19 variant was a global concern, with some data suggesting the variant has “increased transmissibility” compared with other strains.

Outside India, the UK has recorded the highest number of cases of the Indian variant, at 1,587 cases to date. The US, Singapore and Germany are the only other countries to have sequenced more than 100 cases of the B.1.617+ variant, according to the Gisaid Initiative.

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Scientists launch search for genetic test to spot killer prostate cancer

Gene-screening, as is used to detect some breast cancer risks, could save thousands of lives

Scientists have begun work to create a prostate cancer screening service for the UK. In a few years, middle-aged men could be tested to reveal their genetic susceptibility to the condition, with those deemed to be under significant threat of developing it being offered treatment or surgery.

The service would tackle a disease that has become the nation’s most commonly diagnosed cancer and would parallel Britain’s breast cancer screening programme. Every year, more than 47,500 men are diagnosed with prostate cancer: 129 a day on average. More than 11,500 deaths from the disease occur each year, with one in eight men being diagnosed with prostate cancer at some time in their lives.

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Workers at Indonesian pharma firm arrested over ‘reused’ Covid swabs

Nasal swabs allegedly washed, repackaged and sold to passengers required to take test at Medan airport

Staff at an Indonesian pharmaceutical company have been accused of washing and repackaging used Covid nasal swabs, which were then sold to thousands of unsuspecting travellers.

Five employees from the state-owned Kimia Farma have been arrested, while the company may also face a civil lawsuit over the claims.

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As UK nears zero Covid deaths, there’s good reason for optimism

Analysis: the vaccine strategy and staggered easing of restrictions have worked well. The next step is crucial

The handling of the coronavirus crisis in the UK has provided few moments to celebrate, but the day we reach zero deaths from the disease will clearly be one to toast. That day may not be far off. On Tuesday, the UK reported four Covid deaths within 28 days of a positive test. On Monday it was only one. Months of painful lockdown, in the face of more transmissible variants, and the rapid rollout of effective vaccines, have proven their worth. We have good reason to feel optimistic for the months ahead.

No one will have forgotten the brutal winter. In January alone, the UK reported nearly 32,000 Covid deaths, an appalling tally directly linked to locking down too late. In April, the death toll fell to 753. This month, scientists advising the government expect deaths to fall further. It is worth remembering that it’s been more than nine months since the UK last reported zero Covid deaths. We may see more in May, though people will continue to die of Covid, and the numbers might well rise again when restrictions are lifted on indoor mixing.

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Covering India’s Covid crisis: ‘Hundreds of journalists have lost their lives’

Our South Asia correspondent reflects on a catastrophe that is now affecting the lives of almost everyone in the country


You recently lost a close colleague, Kakoli Bhattacharya, to Covid-19. Can you tell us about her
and the important work that she did?

Kakoli was the Guardian’s news assistant over here and had worked for us since 2009. She could find any number or contact I needed and smoothed over any and all of the bureaucratic challenges that working in India can present. She made reporting here a huge joy, when it could be a huge challenge, and she was hugely well thought of by journalists for other organisations too. More than that, though, she was the person who welcomed me to Delhi. She knew the region inside out. She was incredibly warm and was someone I could always call on. The Guardian’s India coverage won’t be the same without her.

Related: ‘Warm, kind, wise and brilliant’: Guardian writers remember Kakoli Bhattacharya

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Scientists find way to remove polluting microplastics with bacteria

Sticky property of bacteria used to create microbe nets that can capture microplastics in water to form a recyclable blob

Microbiologists have devised a sustainable way to remove polluting microplastics from the environment – and they want to use bacteria to do the job.

Bacteria naturally tend to group together and stick to surfaces, and this creates an adhesive substance called “biofilm” – we see it every morning when brushing our teeth and getting rid of dental plaque, for example. Researchers at the Hong Kong Polytechnic University (PolyU) want to use this sticky bacteria property and create tape-like microbe nets that can capture microplastics in polluted water to form an easily disposable and recyclable blob.

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Q&A: Covid vaccines offered to people 42 and over in England – what happens next?

Younger people invited to get jab at more than 1,600 sites across country

The Covid-19 vaccine rollout has been extended in England for the second time in two days. Adults aged 42 and over are now able to book their jab.

Here are your questions answered as the NHS in England takes another step forward in the biggest vaccination programme in its history.

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Covid ‘vaccination persuasion’ teams reap rewards in Turkey

Door-to-door initiative targeting elderly people reluctant to have jab to be rolled out after local success

A coronavirus “vaccination persuasion” initiative targeting elderly people who have declined invitations to get vaccinated is gearing up to be rolled out across Turkey after proving a resounding success in a district in the country’s south-east.

Since February, doctors and healthcare workers in the mainly Kurdish city of Adıyaman, or Semsûr‎, have been calling people in age groups already eligible for the vaccine to ask why they have not come to clinics for appointments.

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Mutations, politics, vaccines: the factors behind India’s Covid crisis

Analysis: experts believe a number of things coalesced to cause the world’s worst coronavirus outbreak

India is now identifying more than 1 million coronavirus cases every three days, with many times more thought to be going unregistered in a vast country where public health surveillance is often poor. Daily deaths exceeded 2,800 on Sunday, but these too are thought to be many times higher.

Epidemiologists and other experts are speculating that several factors have coalesced over the past months to bring India to the point of the world’s worst Covid-19 outbreak.

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Secrets of a tree whisperer: ‘They get along, they listen – they’re attuned’

Suzanne Simard revolutionised the way we think about plants and fungi with the discovery of the woodwide web. The ecologist’s new book shares the wisdom of a life of listening to the forest

When Suzanne Simard made her extraordinary discovery – that trees could communicate and cooperate through subterranean networks of fungi – the scientific establishment underreacted. Even though her doctoral research was published in the Nature journal in 1997 – a coup for any scientist – the finding that trees are more altruistic than competitive was dismissed by many as if it were the delusion of an anthropomorphising hippy.

Today, at 60, she is professor of forest ecology at the University of British Columbia and her research of more than three decades as a “forest detective” is recognised worldwide. In her new book, Finding the Mother Tree – a scientific memoir as gripping as any HBO drama series – she wants it understood that her work has been no brief encounter: “I want people to know that what I’ve discovered has been about my whole life.” Her moment has come: research into forest ecosystems and mycorrhizal networks (those built of connections between plants and fungi) is now mainstream and there is a hunger for books related to the subject: Peter Wohlleben’s The Hidden Life of Trees and Merlin Sheldrake’s Entangled Life – about the hidden life of fungi – extend her thinking about the “woodwide web”, while the heroine of Richard Powers’s Pulitzer prize-winning 2018 novel The Overstory is said to have been inspired by Simard.

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