Indian schoolboy invents affordable smart spoon for trembling hands

A 17-year-old with a passion for robotics has produced a cheaper utensil that uses sensors to cancel out hand tremors

The motivation for his invention came to Aarrav Anil last year when he saw his uncle Arjun, who has Parkinson’s disease, struggle to eat. Some food spilled out of his mouth, the rest splattered on his clothes. Arjun attempted to keep his dignity but the frustration forced the retired civil servant, who is in his 70s, to give up and call his helper to feed him.

The sight of his uncle’s tremors shaking the spoon so violently inspired Aarrav, 17, from Bengaluru, south India, to turn to robotics. He locked himself in his room with microcontrollers, sensors, motors, and a 3D printer. What emerged was a prototype of a smart spoon that is now undergoing trials at the RV College of Physiotherapy in Bengaluru.

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Jesse Jackson to step down as head of civil rights organisation

Retirement from Rainbow PUSH Coalition follows several health problems in recent years

The US civil rights leader Jesse Jackson is to step down down as head of the Chicago-based Rainbow PUSH Coalition he founded.

The organisation announced on Friday that the civil rights leader and two-time presidential candidate would be celebrated this weekend at the coalition’s annual convention.

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Jeremy Paxman bows out as host of University Challenge

Former Newsnight presenter, 73, will end stint as longest serving current quizmaster on British television

Jeremy Paxman’s stint as the longest serving current quizmaster on British television will come to an end on Monday night when he presents his final edition of University Challenge.

The 73-year-old former Newsnight presenter is bowing out from the show after revealing he has been diagnosed with Parkinson’s disease.

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‘I won’t be 80’: Michael J Fox describes struggles with Parkinson’s

The actor, who was diagnosed aged 29, said advancing disease had caused him a string of injuries but he was still able to remain optimistic

Back to the Future star Michael J Fox described Parkinson’s as a “gift that keeps on taking” in an interview on CBS Sunday Morning, in which he described his struggles with the illness.

The 61-year-old activist and former Hollywood actor was diagnosed with young-onset Parkinson’s disease a year after Back to the Future Part III was released in 1990.

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Exposure to environmental toxins may be root of rise in neurological disorders

Doctors warn exposure to omnipresent yet poorly understood chemicals such as microplastics could play a role in dementia

The mystery behind the astronomical rise in neurological disorders like Parkinson’s disease and Alzheimer’s could be caused by exposure to environmental toxins that are omnipresent yet poorly understood, leading doctors warn.

At a conference on Sunday, the country’s leading neurologists and neuroscientists will highlight recent research efforts to fill the gaping scientific hole in understanding of the role environmental toxins – air pollution, pesticides, microplastics, forever chemicals and more – play in increasingly common diseases like dementias and childhood developmental disorders.

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Lars von Trier diagnosed with Parkinson’s disease

Danish director, who won Palme d’Or for Dancer in the Dark, said to be ‘in good spirits’

Lars von Trier, the acclaimed and controversial Danish director, has been diagnosed with Parkinson’s disease, his production company has announced.

In a statement released on Monday, Zentropa – which von Trier co-founded in 1992 with producer Peter Aalbæk Jensen – said the director is in “good spirits and is being treated for his symptoms” while he completes the upcoming final season of his TV trilogy series.

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‘Deeply honoured’: Billy Connolly to receive Bafta fellowship

Comedian says he does not let Parkinson’s disease dictate who he is, as he speaks of delight at accolade

Sir Billy Connolly said he does not let his Parkinson’s disease dictate who he is as he spoke of his honour at receiving this year’s Bafta fellowship.

The 79-year-old comedian, known as the Big Yin, will be celebrated for a career spanning more than five decades at the awards ceremony on 8 May. The fellowship is the highest Bafta accolade given to recognise outstanding and exceptional contribution in film, games or television.

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How biodiversity loss is jeopardising the drugs of the future

From willow bark to mosquitoes, nature has been a source of vital medications for centuries. But species die-off caused by human activity is putting this at risk

What will biodiversity loss mean for drug discovery?
Traditionally used as a painkiller for headaches, snowdrops are now known to slow the onset of dementia. In the 1950s, a natural alkaloid called galantamine was extracted from the bulbs. Today, a synthesised version of this is used to treat Alzheimer’s disease and scientists are investigating further to see if snowdrops might also be effective in the treatment of HIV.

However, over-harvesting has resulted in many snowdrop species becoming threatened. The snowdrop isn’t alone – plants are an abundant source of potential new medicines, often providing us with chemical templates for the design of novel drugs. Yet scientists across the globe say unsustainable use of wild medicinal plants is contributing to biodiversity loss and could limit opportunities to source medicines from nature in the future.

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People with chronic conditions among most at risk from Covid even after jabs

Research finds those with Down’s syndrome, Parkinson’s and other conditions may benefit from booster dose

People living with chronic conditions such as Down’s syndrome and dementia remain among the most vulnerable to Covid-19 even after vaccination, research has found.

The study, based on data from more than 6.9 million vaccinated adults, 5.2 million of whom had received both doses, found that being vaccinated offers powerful protection against hospitalisation for almost all groups. However, a risk calculator based on the data shows that some groups remain at particular risk and may benefit from booster vaccine doses and treatments such as monoclonal antibodies.

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Michael J Fox: ‘Every step now is a frigging math problem, so I take it slow’

After living with Parkinson’s for 30 years, the actor still counts himself a lucky man. He reflects on what his diagnosis has taught him about hope, acting, family and medical breakthroughs

The last time I spoke to Michael J Fox, in 2013, in his office in New York, he was 90% optimistic and 10% pragmatic. The former I expected; the latter was a shock. Ever since 1998, when Fox went public with his diagnosis of early-onset Parkinson’s disease, he has made optimism his defining public characteristic, because of, rather than despite, his illness. He called his 2002 memoir Lucky Man, and he told interviewers that Parkinson’s is a gift, “albeit one that keeps on taking”.

During our interview, surrounded by the memorabilia (guitars, Golden Globes) he has accrued over the course of his career, he talked about how it had all been for the best. Parkinson’s, he said, had made him quit drinking, which in turn had probably saved his marriage. Being diagnosed at the heartbreakingly young age of 29 had also knocked the ego out of his career ambitions, so he could do smaller things he was proud of – Stuart Little, the TV sitcom Spin City – as opposed to the big 90s comedies, such as Doc Hollywood, that were too often a waste of his talents. To be honest, I didn’t entirely buy his tidy silver linings, but who was I to cast doubt on whatever perspective Fox had developed to make a monstrously unjust situation more bearable? So the sudden dose of pragmatism astonished me. Finding a cure for Parkinson’s, he said, “is not something that I view will happen in my lifetime”. Previously, he had talked about finding “a cure within a decade”. No more. “That’s just the way it goes,” he said quietly. It was like a dark cloud had partly obscured the sun.

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Air pollution particles in young brains linked to Alzheimer’s damage

Exclusive: if discovery is confirmed it will have global implications as 90% of people breathe dirty air

Tiny air pollution particles have been revealed in the brain stems of young people and are intimately associated with molecular damage linked to Alzheimer’s and Parkinson’s disease.

If the groundbreaking discovery is confirmed by future research, it would have worldwide implications because 90% of the global population live with unsafe air. Medical experts are cautious about the findings and said that while the nanoparticles are a likely cause of the damage, whether this leads to disease later in life remains to be seen.

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Growing evidence suggests Parkinson’s disease starts in gut

Research shows key proteins in disease can spread from gastrointestinal tract to brain

Evidence that Parkinson’s disease may start off in the gut is mounting, according to new research showing proteins thought to play a key role in the disease can spread from the gastrointestinal tract to the brain.

The human body naturally forms a protein called alpha-synuclein which is found, among other places, in the brain in the endings of nerve cells. However, misfolded forms of this protein that clump together are linked to damage to nerve cells, a deterioration of the dopamine system and the development of problems with movement and speech – hallmarks of Parkinson’s disease.

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Jilly Cooper hasn’t taken a holiday in 22 years because she can’t…

Mark Sanford LOSES his primary after Trump alluded to his extramarital affair and endorsed his opponent hours before polls closed in the Republican congressman's district I haven't had a holiday for 22 years because I can't bear leaving my beloved greyhound, reveals Jilly Cooper But Jilly Cooper is so reluctant to be parted from hers she hasn't taken a holiday abroad in more than 20 years. The 81-year-old has had the dog since 2010 and has described her as her 'dearest companion' since the death of her husband from Parkinson's disease five years ago.