US could loosen some restrictions on prescribing opioids

CDC considers rolling back limits on which doses can be prescribed and for how many days in cases of acute pain

The US could see loosened guidance around prescribing opioids, as the US Centers for Disease Control and Prevention (CDC) considers relaxing some of its guidelines in a move that could signal a new direction for managing chronic pain.

The CDC last Thursday released proposed changes to its guidance on prescribing opioids, rolling back limits on which doses can be prescribed and for how many days in cases of acute pain.

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The big idea: is it time to stop worrying about stress?

Our beliefs about difficult feelings may do more damage than the feelings themselves

In the late 19th-century America, a somewhat bizarre form of abstinence emerged. The vice was not alcohol but anxiety. Citizens of New York began to attend regular “Don’t Worry Clubs” in which they encouraged each other to look on the bright side of life. Their founder, Theodore Seward, argued that Americans were “slaves to the worrying habit”, which was the “enemy which destroys happiness”. It needed to be “attacked” with “resolute and persevering effort”.

By the early 20th century, the psychologist William James described how people had developed a kind of “religion of healthy-mindedness” with the aim of turning the mind away from all negative thoughts and feelings.

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Caesareans or vaginal births: should mothers or medics have the final say?

More babies are born by C-section than ever, causing alarm at the WHO. But some believe the option should always be offered. So what are the risks and benefits?

When Elizabeth Chloe Romanis first considered the ethics of chosen caesarean sections, she was listening to a radio programme her husband had sent her. The programme was about how some NHS trusts refused to give medically unnecessary C-sections to people who wanted them. “He sent it to me like: ‘Have you heard this?’ and obviously I got very annoyed,” says the biolaw researcher at Durham University.

Someone phoned in and asked, why should the NHS offer the choice when childbirth is natural and surgery costs money? Irritated, Romanis thought someone from her field ought to argue for the right to choose. “So that’s what I did,” she says.

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‘Don’t take the damn thing’: how Spotify playlists push dangerous anti-vaccine tunes

Conspiracy theory songs claiming Covid-19 is fake and calling vaccine ‘poison’ are being actively promoted in Spotify playlists

Songs that claim Covid-19 is fake and describe the vaccines as “poison” are being actively promoted to Spotify users in playlists generated by its content recommendation engine.

Tracks found on the world’s largest music streaming service explicitly encourage people not to get vaccinated and say those who do are “slaves”, “sheep”, and victims of Satan. Others call for an uprising, urging listeners to “fight for your life”.

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How DNA link could unlock mystery of cancer patients ‘wasting away’

New research into sudden weight loss finds a possible cause of cachexia in cancer patients and Cockayne syndrome in children

One of the most serious impacts of cancer is the sudden loss of weight, appetite, and muscle that can hit some patients in the later stages of the disease. This wasting syndrome is known as cachexia and it can be triggered in other serious conditions, including heart disease and HIV.

In addition, an inherited version of extreme wasting syndromes can affect children. Known as Cockayne syndrome, it causes them to suffer severe malnutrition and wasting that parallels the effect of cachexia.

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‘Relentless calls and constant abuse’: why Britain’s vets are in crisis

Vets are no strangers to pressure, but Covid and the huge boom in pets means they have never been busier – or experienced so much stress

By the summer of 2020, veterinary practices were beginning to feel the effects of the pandemic pet boom. That was the time that Melanie, a small-animal vet from the southeast of England, realised she no longer wanted to be in the profession. The feeling left her at a loss. All she’d ever done was eat, breathe and sleep veterinary medicine. Like many vets she had been inspired since she was a child: religiously watching TV shows such as Animal Hospital and Vets in Practice, mucking out stables to embellish her university application and completing a five-year degree before finding work at a busy practice. It was a vocation, not a job: she simply loved animals. “Ever since I knew what a vet was, I wanted to be one,” she says. “I don’t remember a time when I didn’t want to do that – until now.”

But for Melanie, the pressure of lockdown was just the start. During the initial mayhem, practices were forced to work within strict Covid restrictions. Many team members were off sick, isolating or furloughed. Melanie worked three shifts on, three shifts off with a skeleton staff, clocking two hours’ overtime every evening out of a sense of duty. The busiest day in the practice calendar was usually Boxing Day. But between March and July 2020, says Melanie, every day felt as if it was Boxing Day “if the toilet was flooded and the lab was on fire”. Staff bounced from the reception to operations, from remote appointments to emergencies, shepherding animals in for treatment from the street while brushing off abuse from stressed-out owners who were unhappy about wearing masks, didn’t want to wait outside or refused to accept that they couldn’t receive a home visit to have their cat’s claws clipped.

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I’ll fight to overturn US ban on my ‘Queer Bible’, says British author

Former model Jack Guinness caught up in furore over Mississippi mayor’s attempt to withhold funding for library until ‘homosexual materials’ are withdrawn

A British writer, presenter and former model says he is shocked to find himself at the centre of an unprecedented wave of book banning in the US.

A Mississippi mayor has told the Madison County Library to remove LGBTQ+ books from its shelves or lose funding. One of the books singled out as an example was The Queer Bible, a collection of LGBTQ+ history essays edited by Jack Guinness. Ridgeland’s Republican mayor, Gene McGee, has refused to release funds to the library until “homosexual materials” are withdrawn.

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Sadiq Khan pledges to end toxic culture at Met police and signals showdown with Priti Patel

The London mayor vows to oppose anyone who fails to understand deep problems at beleagured force, in wake of Cressida Dick resignation

Sadiq Khan, the mayor of London, today sets the stage for a dramatic showdown with the home secretary, Priti Patel, over who should be the next Metropolitan police commissioner as he vows to oppose anyone who does not understand the deep “cultural problems” within the beleaguered force.

Writing in the Observer, three days after his intervention forced Cressida Dick to abruptly resign, Khan says recent revelations of officers bragging about violence towards women and exchanging racist and Islamophobic messages rekindled personal memories of the “bad old days of the Met” during his own childhood.

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Next Covid strain could kill many more, warn scientists ahead of England restrictions ending

Demands grow for government science chiefs to reveal evidence backing move to lift last protective measures

A future variant of Covid-19 could be much more dangerous and cause far higher numbers of deaths and cases of serious illness than Omicron, leading UK scientists have warned.

As a result, many of them say that caution needs to be taken in lifting the last Covid restrictions in England, as Boris Johnson plans to do next week.

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Boris Johnson should be ashamed of Savile slur, says bishop

Paul Bayes, retiring bishop of Liverpool, calls for an end to ‘rancid and dangerous’ political culture in Britain

Today’s political culture is “rancid and dangerous” and Boris Johnson should be ashamed of telling a lie that led to street violence, a senior Church of England bishop has said.

Paul Bayes, the bishop of Liverpool, said the UK was facing a “struggle between those in whose interest it is to fragment society and those who want to sustain the common good”.

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What gambling firms don’t want you to know – and how they keep you hooked

From brain hacks to dark nudges and near misses – betting companies employ an arsenal of clever tricks to tempt punters into spending more money. Here’s how …

Each year, British punters lose more than £11bn to the gambling industry, equivalent to nearly £164 for every man, woman and child in the UK. This money-spinning national love affair with betting owes much to the liberalisation of gambling laws under Tony Blair’s Labour government in 2005. The growth of the UK betting sector since then has created billionaires, such as Bet365’s Denise Coates and Betfred’s Done brothers. At the other end of the scale, what starts out as a harmless flutter has driven countless customers into financial ruin, family breakups, and worse.

The betting industry promotes its wares predominantly through advertising on TV, social media or via wall-to-wall sponsorship of football clubs. But gambling has always been different from other consumer products. Coca-Cola advertises in the knowledge that you probably already know how it tastes. The occasional memory jog will remind you why you like it, and might lead you to buy more and to choose Coke over Pepsi when you do. Convincing a customer to choose your brand – and remain loyal – is only half the battle with gambling. Betting firms also need to persuade punters that they have a decent shot at winning some money, even though – in the long term at least – they don’t.

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‘Welcome to England. How are you doing?’: the artist who holds out a hand to refugees

Marie Gracie helps families arriving from Afghanistan. The Guardian angel sends a party entertainer to help the children adjust to their first English winter

Marie Gracie never met the boy, but his fate changed her life. On 2 September 2015, three-year-old Alan Kurdi washed up, drowned, on a Turkish beach. His family were Syrian refugees, trying to reach Europe. Journalist Nilüfer Demir took a photo. Alan lies face down, in a T-shirt and shorts. His feet are so tiny. His hands are upturned, facing the sky.

“I’m a mother,” says Gracie, an artist from Milton Keynes. “Can you imagine anything worse than your child being in the news like that?” She reached out to her local chapter of Refugees Welcome, set up in the wake of the Syrian war.

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‘Anything to stop the massacres’: peace still eludes DRC as armed groups proliferate

After years of conflict between the DR Congo’s ineffective army, rebel forces and local militias, can Uganda’s entry into the war bring peace?

For the past three months, Ugandan forces have been bombarding Islamist rebels in its border region with the Democratic Republic of the Congo. The offensive, in the Rwenzori mountain range that straddles both countries, has forced many Congolese to leave their homes and move to the cities for shelter.

Sarah Kasanga* is one. The Allied Democratic Force (ADF) militia stormed Kalingathe, her village north of Beni, in December 2019. People were made to lie on the floor while rebels searched homes for food, pots, money or clothes.

DRC soldiers overlook Virunga national park at a military base on the outskirts of Beni

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Living in a woman’s body: I was mutilated – and I swore I would stop this happening to another girl

I was told I was a coward if I resisted female genital mutilation. For decades since then, I have worked, and risked everything, to protect other girls

I was 14 when my mother and grandmother announced that I was going to have my clitoris, my labia majora and my labia minora cut out. They said that if I resisted I was a coward. In my culture, the worst thing you can be called is a coward.

I was never naive. I grew up as a Maasai girl in Kenya in the 60s and 70s. At some point in my childhood, I became aware that there was a rite of passage into womanhood. I was to have my vulva mutilated by an elderly woman using a blunt instrument. But I was also part of the first generation of Maasai girls to be sent to school, where I met girls from communities who didn’t practise female genital mutilation (FGM). I learned from them that you can grow to be an adult with your vulva intact. That was what I wanted.

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‘They’ll have to carry me out in a box’: inside the apartments of the luckiest renters

They scored beautiful New York City homes for far below market rate – and no, they’re never leaving

For most, finding an apartment with the right balance of square footage, amenities, neighborhood, and monthly rent is akin to a competitive sport. These New Yorkers – who lucked into the housing lottery, moved in decades ago, or inherited – placed on the podium and are staying put.

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Covid rules are to be axed in England, but is pandemic’s end really in sight?

Analysis: Plans to end isolation rules have been gleefully announced, but questions about infection control remain

As the threat of the Omicron wave has receded in England, the government has been quick to move the conversation on to “living with Covid”.

It was inevitable that this would mean the eventual lifting of legal restrictions, including the need to self-isolate. But even given the optimistic tone in recent weeks, Boris Johnson’s announcement on Wednesday came sooner than many expected.

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Living in a woman’s body: this body is a genetic mistake – but it is sex, laughter and beauty too

It is radical to love a body that the world says is wrong – and I love mine completely

This body is a genetic mistake, a pitiable stare, the scan on a mundane Tuesday lunchtime with a doctor speaking in hushed tones by the bed.

It is glorious too, thanks. It is deep-in-the-bones laughter at 2am with people who love you; only strangers care that it is sitting in a wheelchair while doing so (“Have you got a licence for that thing, sweetheart?”). It is straight-As, promotions and beating expectations as much as the odds. It is being buckled over from the pain, clutching a public toilet bowl, pills and dignity rattling at the bottom of a handbag. It is sex, fevered goosebumps and kisses to the skin like magic. It is warm summers with friends, sunshine on bare legs and 90s dance music ricocheting through the air. It is fucking knackered.

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Living in a woman’s body: the Taliban fear our beauty, strength – and resistance

Growing up in Afghanistan I was taught to hide my body. Now I see it as a symbol of rebellion against those who would try to control me

As a child, I never rode bicycles or played sports such as gymnastics and karate because it was “not good for girls”. I later understood it was to avoid the risk of breaking my hymen and “losing” my virginity, but I only understood the magnitude of this “loss” when my cousin and best friend got married. She had been abused by a mullah – a religious cleric – as a baby. Her mother was less worried about the trauma caused to her daughter by the abuse than she was about her daughter’s hymen having been broken as a result.

These fears were not misplaced. When my cousin did not bleed on her wedding night, she was sent back to her mother’s home the next morning beaten black and blue. Nobody questioned or blamed the husband.

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